• JSTS:Journal of Semiconductor Technology and Science
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• 제2권1호
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• pp.41-48
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• 2002

This paper presents a 18-mW, 2.5-㎓ fractional-N frequency synthesizer with l-bit $4^{th}$-order interpolative delta-sigma ($\Delta{\;}$\sum$)modulator to suppress fractional spurious tones while reducing in-band phase noise. A fractional-N frequency synthesizer with a quadruple prescaler has been designed and implemented in a $0.5-\mu\textrm{m}$ 15-GHz $f_t$ BiCMOS. Synthesizing 2.1 GHzwith less than 200 Hz resolution, it exhibits an in-band phase noise of less than -85 dBc/Hz at 1 KHz offset frequency with a reference spur of -85 dBc and no fractional spurs. The synthesizer also shows phase noise of -139 dBc/Hz at an offset frequency of 1.2 MHz from a 2.1GHz center frequency.

• 한국식품위생안전성학회지
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• 제32권4호
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• pp.249-253
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• 2017

본 연구는 자동화 MPN 분석 장비인 TEMPO (TEMPO BC)와 MYP 배지법을 이용한 바실러스 정량 시험 결과에 대한 상관관계와 유의성을 연구하였다. 자연적으로 오염되어 있는 B. cereus 다빈도 검출 식품을 선별하여(N = 384) 두 시험법으로 정량 시험한 결과값의 차가 1 log CFU/g 미만이 95.3%였으며, B. cereus가 검출된 시료에서는 92.5%였다. 통계학적으로 TEMPO BC 시험법과 MYP 배지법은 유의적 차이가 없었다(p < 0.05). 국내 정량 규격이 있는 식품에 인위적으로 B. cereus를 접종하고 두 시험법을 비교하였다. $R^2$값은 소스류(0.98), 조림식품류(0.98), 젓갈류(0.96)에서 유의적인 차이가 없었으나, 생식류(0.94), 청국장류(0.86), 된장류(0.71)는 시험법 간의 유의적인 차이가 있었다. 콩, 메밀 등의 곡류 제품은 TEMPO BC 결과값의 오류가 날 수 있는 재료로 명시되어 있으므로 선식류와 청국장류, 된장류는 자동화 시험법인 TEMPO BC로 사용하기 위해서는 시험법을 추가적으로 검증 할 필요성이 있다고 생각된다. 자연적으로 오염되어 있는 식품 시료와 인위적으로 접종한 시료에 대한 선형 방정식은 $log(TEMPO\;BC)=0.8453{\times}log$ (MYP배지) + 0.1642이며 paired t-test를 이용하여 검증한 결과 유의적인 차이가 없었다. 최근 식품의 안전성에 대한 소비자의 관심이 증가하여 식품공전 및 국제 기준에 정량기준이 강화되고 있는 추세이므로 TEMPO BC의 수요증가가 예상된다. 따라서 본 연구는 이에 대비하여 식품의 안전성 평가에 사용되는 기존의 실험법과의 비교 및 타당성 연구 기초 자료로 쓰일 것이라 생각된다.

• JSTS:Journal of Semiconductor Technology and Science
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• 제9권3호
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• pp.153-159
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• 2009

A CMOS frequency synthesizer for $5{\sim}6$ GHz UNII-band sub-harmonic direct-conversion receiver has been developed. For quadrature down-conversion with sub-harmonic mixing, octa-phase local oscillator (LO) signals are generated by an integer-N type phase-locked loop (PLL) frequency synthesizer. The complex timing issue of feedback divider of the PLL with large division ratio is solved by using multimodulus prescaler. Phase noise of the local oscillator signal is improved by employing the ring-type LC-tank oscillator and switching its tail current source. Implemented in a $0.18{\mu}m$ CMOS technology, the phase noise of the LO signal is lower than -80 dBc/Hz and -113 dBc/Hz at 100 kHz and 1MHz offset, respect-tively. The measured reference spur is lower than -70 dBc and the power consumption is 40 m W from a 1.8 V supply voltage.

• International Journal of Industrial Entomology and Biomaterials
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• 제3권2호
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• pp.187-190
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• 2001

Inheritance pattern of resistance to Bombyx mori nuclear polyhedrosis virus (BmNPV) was studied in an Indian silkworm stock TX by single back-cross test method. The resistant parent ［TX］, susceptible parent ［HM］, their Fl, F2, and Fl progeny back-crossed to TX [BC(R)] and HM [BC(S)] were inoculated per os with a fixed concentration of BmNPV($0.5{\times}10^{th} PIB/ml$) on the first day of second stadium. The cumulative mortality was recorded until day $10^{\times}$ post-inoculation. The results show that the resistance to BmNPV in TX fellow mono Mendelian inheritance pattern. The resistance dominated over the susceptibility at Fl. At F2, the resistant and susceptible offspring segregated in 3:1 ratio whereas at BC(S), the resistant and susceptible offspring segregated in 1:1 ratio. The response of BC(R) was more or less like the resistant parent TX which confirms the involvement of a major dominant gene conferring resistance to BmNPV in TX. The possible mechanism of inheritance of resistance in TX is discussed.

• 한국환경과학회지
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• 제28권1호
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• pp.107-123
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• 2019

The aerosol chemical components in $PM_{2.5}$ in several regions (Seoul, Busan, Daejeon, and Jeju Island) were investigated with regard to their concentration characteristics and optical properties. The optical properties of the various aerosol components (e.g., water-soluble, insoluble, Black Carbon (BC), and sea-salt) were estimated using hourly and daily aerosol sampling data from the study area via a modeling approach. Overall, the water-soluble component was predominant over all other components in terms of concentration and impact on optical properties (except for the absorption coefficient of BC). The annual mean concentration and Aerosol Optical Ddepth (AOD) of the water-soluble component were highest in Seoul (at the Gwangjin site) ($26{\mu}g/m^3$ and 0.29 in 2013, respectively). Further, despite relatively moderate BC concentrations, the annual mean absorption coefficient of BC ($21.7Mm^{-1}$) was highest in Busan (at the Yeonsan site) in 2013, due to the strong light absorbing ability of BC. In addition, high AODs for the water-soluble component were observed most frequently in spring and/or winter at most of the study sites, while low values were noted in summer and/or early fall. The diurnal variation in the AOD of each component in Seoul (at the Gwangjin site) was slightly high in the morning and low in the afternoon during the study period; however, such distinctions were not apparent in Jeju Island (at the Aweol site), except for a slightly high AOD of the water-soluble component in the morning (08:00 LST). The monthly and diurnal differences in the AOD values for each component could be attributed to the differences in their mass concentrations and Relative Humidities (RH). In a sensitivity test, the AODs estimated under RH conditions of 80 and 90% were factors of 1.2 and 1.7 higher, respectively, than the values estimated using the observed RH.

• 한국전자파학회논문지
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• 제24권10호
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• pp.971-978
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• 2013

본 논문에서는 65 nm RF CMOS 공정을 이용하여 26 GHz 위상 고정 루프(PLL)를 설계하고, 주파수 3체배기(tripler)를 이용하여 W 밴드 주파수 합성기를 설계하였다. 26 GHz VCO는 22.8~26.8 GHz, 3체배기의 출력은 74~75.6 GHz의 주파수 조정 범위를 갖는다. 제작한 주파수 합성기는 총 75.6 mW의 전력을 소모하며, 3체배기의 최종 출력은 1 MHz 오프셋에서 -75 dBc/Hz, 10 MHz 오프셋에서 -101 dBc/Hz의 위상 잡음 특성을 갖는다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권1호
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• pp.43-45
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• 2013

Background: The aim of this epidemiological study was to establish the laterality of breast cancer (BC) and its association with size, receptor status of the primary tumor and bone metastasis (BM) in a local population. Materials and Methods: This retrospective study included cases of BC from Jan-2009 to Dec-2011 who were referred for metastatic work up or follow up survey with Technetium-99m MDP bone scan (BS) to the Nuclear Medicine Department of Karachi Institute of Radiotherapy and Nuclear Medicine (KIRAN). A total of 384 patients out of 521 were included and all reviewed for age, primary tumor size (PTS), laterality, receptor status like estrogen receptor (ER) progesterone receptor (PR) and Her-2-Neu receptor, presence or absence of BM with sites of involvement and time interval between diagnosis of BC and appearance of BM. Results: The left to right sided BC proportion was significantly higher than unity (59%:41%; p<0.001). The right sided BC was observed in younger age group (46:52 years; p<0.0001) and with a smaller PTS than the left sided (3.43:4.15 cm; p<0.0001). The patients with BM had relatively higher negative receptor status with a significant predominance of right sided BC. The overall incidence of BM on BS was 28% and relatively higher in right than left breast (33%:24% p=0.068). The average number of BM sites was also significantly greater for the right side (6:4, P<0.0001). The % cumulative risk of BM in right breast was noted at significantly smaller PTS than left side with log rank value of 5.579; p<0.05. The Kaplan Meier survival plot for event free survival of BM in left sided BC was significantly higher than for the right side (log rank value=4.155, p<0.05), with an earlier appearance of BM in right BC. Conclusions: 1) A left sided predominance of BC was seen in local population; 2) right sided BC had a more aggressive behavior with extensive and earlier appearance of BM at relatively younger age, smaller PTS and receptor (s) negativity.

• 대한전자공학회논문지TC
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• 제41권10호
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• pp.79-86
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• 2004

본 논문은 0.35㎛ CMOS 공정을 이용하여 1.070GHz와 2.07GHz의 주파수를 생성해내는 이중 대역 전압 제어 발진기를 제안한다. 50% 듀티 싸이클 회로와 반가산기를 가진 제안된 전압 제어 발진기는 일반적인 전압 제어 발진기의 주파수보다 두 배 높은 주파수를 생성해낼 수 있다 제안된 전압 제어 발진기의 측정 결과는 전압 제어 발진기 이득과 전력 소모가 각각 561MHz/V, 14.6mW로 나타났다. 이중 대역 전압 제어 발진기의 위상 잡음은 각각 1.07GHz와 2.07GHz로부터 2MHz 옵셋 주파수에서 -102.55dBc/Hz와 -95.88dBc/Hz로 측정되었다.

• 한국산학기술학회논문지
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• 제9권5호
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• pp.1193-1200
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• 2008

본 논문은 질화갈륨 전력 소자를 이용한 이동통신 시스템용 전력증폭기 모듈에 대하여 기술하고 있다. 전치증폭단, 구동증폭단, 그리고 전력증폭단을 각각 설계, 제작하여 그 성능을 측정하고, 이를 바탕으로 통합 모듈을 설계하여 5Watt급 GaN 전력증폭기 모듈을 완성하였다. 하모닉 차단과 ACP를 개선하기 위하여 출력측에 결함접지구조를 삽입하였다. 개발된 질화갈륨 전력증폭기의 성능을 측정한 결과, 2.1GHz대역에서 58dB 이상의 이득, 37bBm 이상의 출력, 50dBc 이상의 하모닉 차단, 2-tone 입력시 35dBc 이상의 IMD3 특성, 그리고 35dBc 이상의 ACP 특성을 얻었다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권3호
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• pp.1437-1443
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• 2016

Background: We investigated four factors, height, weight gain since age 20, physical activity, and alcohol drinking, for associations with risk of breast cancer (BC) according to menopausal status, using the latest data of the Japan Collaborative Cohort Study (JACC Study). Materials and Methods: We confined the analysis to 24 areas available of cancer incidence information, excluding women with a previous diagnosis of BC. Baseline data were collected from 38,610 (9,367 premenopausal, and 29,243 postmenopausal) women during 1988 and 1990. The study subjects were followed-up at the end of 2009, and 273 (84 premenopausal, and 189 postmenopausal) cases of BC were newly diagnosed in 501,907 person-years. The Cox model was used to estimate a hazards ratio (HR) and its 95% confidence interval (CI) of BC risk. Results: As a result of the multivariate analysis adjusting for age at baseline survey, age at menarche, number of live births, and, age at first delivery, weight gain since age 20 of 6.7 kg-9.9 kg, and ${\geq}10.0kg$ were significantly associated with increased risk for postmenopausal BC (HR=2.48, 95% CI 1.40-4.41, and, HR=2.94, 95% CI 1.84-4.70, respectively). Significantly increased trend of BC risk was also observed in weight gain since age 20 (p for trend, p<0.001). Amount of ethanol intake per day${\geq}15.0g$ was significantly associated with increased risk for postmenopausal BC in the multivariable-adjusted analysis (HR=2.74, 95% CI 1.32-5.70). Conclusions: Higher weight gain in adulthood and larger amounts of ethanol intake were significantly associated with increased risk of BC in Japanese postmenopausal women. None of the investigated factors were significantly associated with BC risk in Japanese premenopausal women.