Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
권호 표지
DOI QR코드

DOI QR Code

Weight Gain and Alcohol Drinking Associations with Breast Cancer Risk in Japanese Postmenopausal Women - Results from the Japan Collaborative Cohort (JACC) Study

  • Nitta, Junichi (Department of Public Health, School of Medicine, Sapporo Medical University) ;
  • Nojima, Masanori (Center for Translational Research, The Institute of Medical Science Hospital, the University of Tokyo) ;
  • Ohnishi, Hirofumi (Department of Public Health, School of Medicine, Sapporo Medical University) ;
  • Mori, Mitsuru (Department of Public Health, School of Medicine, Sapporo Medical University) ;
  • Wakai, Kenji (Department of Preventive Medicine/Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine) ;
  • Suzuki, Sadao (Department of Public Health, Nagoya City University Graduate School of Medical Science) ;
  • Fujino, Yoshihisa (Department of Preventive Medicine and Community Health, University of Occupational and Environmental Health) ;
  • Lin, Yingsong (Department of Public Health, Aichi Medical University School of Medicine) ;
  • Tamakoshi, Koji (Department of Nursing, Nagoya University Graduate School of Medicine) ;
  • Tamakoshi, Akiko (Department of Public Health, Hokkaido University Graduate School of Medicine)
  • Published : 2016.04.11
Download PDF
⟨ Previous Next ⟩

Abstract

Background: We investigated four factors, height, weight gain since age 20, physical activity, and alcohol drinking, for associations with risk of breast cancer (BC) according to menopausal status, using the latest data of the Japan Collaborative Cohort Study (JACC Study). Materials and Methods: We confined the analysis to 24 areas available of cancer incidence information, excluding women with a previous diagnosis of BC. Baseline data were collected from 38,610 (9,367 premenopausal, and 29,243 postmenopausal) women during 1988 and 1990. The study subjects were followed-up at the end of 2009, and 273 (84 premenopausal, and 189 postmenopausal) cases of BC were newly diagnosed in 501,907 person-years. The Cox model was used to estimate a hazards ratio (HR) and its 95% confidence interval (CI) of BC risk. Results: As a result of the multivariate analysis adjusting for age at baseline survey, age at menarche, number of live births, and, age at first delivery, weight gain since age 20 of 6.7 kg-9.9 kg, and ${\geq}10.0kg$ were significantly associated with increased risk for postmenopausal BC (HR=2.48, 95% CI 1.40-4.41, and, HR=2.94, 95% CI 1.84-4.70, respectively). Significantly increased trend of BC risk was also observed in weight gain since age 20 (p for trend, p<0.001). Amount of ethanol intake per day${\geq}15.0g$ was significantly associated with increased risk for postmenopausal BC in the multivariable-adjusted analysis (HR=2.74, 95% CI 1.32-5.70). Conclusions: Higher weight gain in adulthood and larger amounts of ethanol intake were significantly associated with increased risk of BC in Japanese postmenopausal women. None of the investigated factors were significantly associated with BC risk in Japanese premenopausal women.

Keywords

References

  1. Chan M-F, Dowsett M, Folkerd E, et al (2007) Usual physical activity and endogenous sex hormones in postmenopausal women: the European prospective investigation into cancer-norfolk population study. Cancer Epidemiol Biomarkers Prev, 16, 900-5. https://doi.org/10.1158/1055-9965.EPI-06-0745
  2. Colditz GA, Baer HJ, Tamimi RA (2006) 51. Breast Cancer. schottenfeld d, fraumeni jf eds. cancer epidemiology and prevention. third ed. oxford univ press, oxford, 995-1012.
  3. Emaus MJ, van Gills CH, Bakker MF, et al (2014). Weight change in middle adulthood and breast cancer risk in the EPIC-PANACEA study. Int J Cancer, 135, 2887-99. https://doi.org/10.1002/ijc.28926
  4. Fagherazzi G, Viller A, Boutron-Ruault MC, et al (2012). Height, sitting height, and leg length in relation with breast cancer risk in the E3N Cohort. Cancer Epidemiol Biomarkers Prev, 21, 1171-5. https://doi.org/10.1158/1055-9965.EPI-12-0130
  5. Hastert TA, Beresford SAA, Patterson RE, et al (2013). Adherence to WCRF/AICR cancer prevention recommendation and risk of postmenopausal breast cancer. Cancer Epidemiol Biomarkers Prev, 22, 1498-1508. https://doi.org/10.1158/1055-9965.EPI-13-0210
  6. Henderson BE, Feigelson HS (2000). Hormonal carcinogenesis. Carcinogenesis, 21, 427-33. https://doi.org/10.1093/carcin/21.3.427
  7. Hirose K, Tajima K, Hamajima N, et al (2001). Association of family history and other risk factors with breast cancer risk among Japanese premenopausal and postmenopausal women. Cancer Causes Control, 12, 349-58. https://doi.org/10.1023/A:1011232602348
  8. Iwasaki M, Otani T, Inoue M, et al (2007). Body size and risk for breast cancer in relation to estrogen and progesterone receptor status in Japan. Ann Epidemiol, 17, 304-12. https://doi.org/10.1016/j.annepidem.2006.09.003
  9. Kabat GC, Heo M, Kamensky V, et al (2013). Adult height in relation to risk of cancer in a cohort of Canadian women. Int J Cancer, 132, 1125-32. https://doi.org/10.1002/ijc.27704
  10. Kanda Y (2013). Investigation of the freely-available easy-to-use software "EZR" (Easy R) for medical statistics. Bone Marrow Transplant, 48, 452-8. https://doi.org/10.1038/bmt.2012.244
  11. Kawai M, Kakugawa Y, Nishino Y, et al (2013). Anthropometric factors, physical activity, and breast cancer risk in relation to hormone receptor and menopausal status in Japanese women: a case-control study. Cancer Causes Control, 24, 1033-44. https://doi.org/10.1007/s10552-013-0181-5
  12. Lin Y, Kikuchi S, Tamakoshi K, et al (2005). Prospective study of alcohol consumption and breast cancer risk in Japanese women. Int J Cancer, 116, 779-83. https://doi.org/10.1002/ijc.20980
  13. Matsuda A, Matsuda T, Shibata A, et al (2013). Cancer incidence and incidence rates in Japan in 2008: A Study of 25 population-based cancer registries for the Monitoring of Cancer Incidence in Japan (MCIJ) Project. Jpn J Clin Oncol, 44, 388-96.
  14. Maruti SS, Willett WC, Feskanich D, et al (2008). A prospective study of age-specific physical activity and premenopausal breast cancer. J Natl Cancer Inst, 100, 728-37. https://doi.org/10.1093/jnci/djn135
  15. Muti P, Quattrin T, Grant BJB, et al (2002). Fasting glucose is a risk factor for breast cancer: a prospective study. Cancer Epidemiol Biomarkers Prev, 11, 1361-8.
  16. Ohno Y, Tamakoshi A (2001). Japan collaborative cohort study for evaluation of cancer risk sponsored by monbusho (JACC Study). J Epidemiol, 11, 144-50. https://doi.org/10.2188/jea.11.144
  17. Peters TM, Schatzkin A, Gierach GL, et al (2009). Physical activity and postmenopausal breast cancer risk in the NIH-AARP Diet and Health Study. Cancer Epidemiol Biomarkers Prev, 18, 289-96. https://doi.org/10.1158/1055-9965.EPI-08-0768
  18. Petri AL, Tjonneland A, Gamborg M, et al (2004). Alcohol intake, type of beverage, and risk of breast cancer in pre- and postmenopausal women. Alcohol Clin Exp Res, 28, 1084-90. https://doi.org/10.1097/01.ALC.0000130812.85638.E1
  19. Seitz HK, Pelucchi C, Bagnardi V, et al (2012) Epidemiology and pathophysiology of alcohol and breast cancer: update 2012. Alcohol Alcohol, 47, 204-12. https://doi.org/10.1093/alcalc/ags011
  20. Stenndof K, Ritte R, Eomios PP, et al (2013). Physical activity and risk of breast cancer overall and by hormone receptor status: the European Prospective Investigation into Cancer and Nutrition. Int J Cancer, 132, 1667-78. https://doi.org/10.1002/ijc.27778
  21. Suzuki R, Iwasaki M, Inoue M, et al (2009). Alcohol consumption-associated breast cancer incidence and potential effect modifiers: the Japan public health center-based Prospective Study. Int J Cancer, 127, 685-95.
  22. Suzuki S, Kojima M, Tokudome S, et al (2008). Effect of physical activity on breast cancer risk: findings of the japan collaborative cohort study. Cancer Epidemiol Biomarkers Prev, 17, 3396-401. https://doi.org/10.1158/1055-9965.EPI-08-0497
  23. Suzuki S, Kojima M, Tokudome S, et al (2013). Obesity/weight gain and breast cancer risk: findings from the japan collaborative cohort study for the evaluation of cancer risk. J Epidemiol, 23, 139-45. https://doi.org/10.2188/jea.JE20120102
  24. Tamakoshi A, Ozasa K, Fujino Y, et al (2013). Cohort profile of the japan collaborative cohort study at final follow-up. J Epidemiol, 23, 227-32. https://doi.org/10.2188/jea.JE20120161
  25. Tjonneland A, Christensen J, Thomsen BL, et al (2004). Lifetime alcohol consumption and postmenopausal breast cancer rate in Denmark: a prospective cohort study. J Nutr, 134, 173-8. https://doi.org/10.1093/jn/134.1.173
  26. Statistics and Information Department, Minister's Secretariat, Ministry of Health, Labour and Welfare (2015). Vital Statistics of Japan 2013. Vol 3. Tokyo: Health Labour and Welfare Statistics Association, Tokyo, 146-7.
  27. Vrieling A, Buck K, Kaaks R, et al (2010). Adult weight gain in relation to breast cancer risk by estrogen and progesterone receptor status. Breast Cancer Res Treat, 123, 641-9. https://doi.org/10.1007/s10549-010-1116-4
  28. Wada K, Nagata C, Tamakoshi A, et al (2014). Body mass index and breast cancer risk in Japan: a pooled analysis of eight population-based cohort studies. Ann Oncol, 25, 519-24. https://doi.org/10.1093/annonc/mdt542
  29. World Cancer Research Fund/American Institute for Cancer Research (2007). Food, nutrition, physical activity, and the prevention of cancer: a global perspective. washington DC, 289-95.
  30. Zhu S, Toyoshima H, Kondo T, et al (2002). Short-term and long-term reliability on previous illness and family history as compared with that on smoking and drinking habits in questionnaire survey. J Epidemiol, 12, 120-5. https://doi.org/10.2188/jea.12.120

Cited by

  1. Modifiable Risk Factors for the Development of Breast Cancer in Young Women vol.24, pp.6, 2018, https://doi.org/10.1097/PPO.0000000000000340
  2. Weight change since age 20 and incident risk of obesity-related cancer in Japan: a pooled analysis of the Miyagi Cohort Study and the Ohsaki Cohort Study pp.00207136, 2019, https://doi.org/10.1002/ijc.31743
  3. Light Alcohol Drinking and Risk of Cancer: A Meta-Analysis of Cohort Studies vol.50, pp.2, 2018, https://doi.org/10.4143/crt.2017.094