• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.6
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• pp.1284-1290
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• 2002

Scrophularia buergeriana Miquel (Scrophulariaceae) has been used as an anti-inflammatory drug in the folk medicine recipe and been proved its anti-inflammatory effect in the oriental medicine. Since nitric oxide (NO) and superoxide anion (O/sub 2//sup -/) are ones of the major inflammatory parameters, we studied the effect of aqueous extracts of Scrophularia buergeriana (SB) on NO and O/sub 2//sup -/ production in lipopolysaccharide (LPS)-stimulated mouse peritoneal macrophages. NO, O/sub 2//sup -/production and inducible NO synthase (iNOS) level were significantly reduced in LPS-activated macrophages by SB compared to those without. Electrophoretic mobility shift assay (EMSA) indicated that SB blocked the activation of NF-kB, which was considered to be a potential transcription factor for the iNOS expression. SB also blocked degradation of IkBα. Furthermore, IkB kinase alpha (IKKα), which phosphorylates serine residues of IkB directly, is inhibited by SB. These results suggest that SB could exert its anti-inflammatory actions by suppressing the activation of NF-kB through inhibition of IKK activity.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.4
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• pp.1281-1284
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• 2012

Background: Platinum-hased chemotherapy for advanced non-small cell lung cancer (NSCLC) is still considered the first choice, presenting a modest survival advantage. However, the patients eventually experience disease progression and require second-line therapy. While there are reliable predictors to identify patients receiving first-line chemotherapy, very little knowledge is available about the prognostic factors in patients who receive second-line treatments. The present study was therefore performed. Methods: We retrospectively reviewed 107 patients receiving second-line treatments from August 2002 to March 2012 in the Dicle University, School of Medicine, Department of Medical Oncology. Fourteen potential prognostic variables were chosen for analysis in this study. Univariate and multivariate analyses were conducted to identify prognostic factors associated with survival. Result: The results of univariate analysis for overall survival (OS) were identified to have prognostic significance: performance status (PS), stage, response to first-line chemotherapy response to second-line chemotherapy and number of metastasis. PS, diabetes mellitus (DM), response to first-line chemotherapy and response to second-line chemotherapy were identified to have prognostic significance for progression-free survival (PFS). Multivariate analysis showed that PS, response to first-line chemotherapy and response to second-line chemotherapy were considered independent prognostic factors for OS. Furthermore, PS and response to second-line chemotherapy were considered independent prognostic factors for PFS. Conclusion: In conclusion, PS, response to first and second-line chemotherapy were identified as important prognostic factors for OS in advanced NSCLC patients who were undergoing second-line palliative treatment. Furthermore, PS and response to second-line chemotherapy were considered independent prognostic factors for PFS. It may be concluded that these findings may facilitate pretreatment prediction of survival and can be used for selecting patients for the correct choice of treatment.

• Korean Journal of Food Science and Technology
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• v.30 no.6
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• pp.1279-1284
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• 1998

This study was designed to investigate the reasonable roasting condition of chicory. Extraction and surface color development of roasted chicory were significantly influenced by roasting temperature and time, and they were increased with increasing time, and roasting at $170^{\circ}C$ showed the highest browning color development. Soluble solid contents was not affected by roasting temperature and time. Roasting for 10min at $150^{\circ}C$ exhibited the highest sensory score, at which the free sugar composition of the extract was 0.87% xylose, 0.62% fructose and 0.84% sucrose. A total of 17 volatile components were identified by GC/MSD from the dried and roasted chicories. Aldehyde, ketone and pyrazine compounds were found to be major volatile flavor components in chicory roots. It was concluded that the results of this work will be useful to determine the optimum conditions for roasting of chicory roots.

• The Journal of the Korea institute of electronic communication sciences
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• v.10 no.11
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• pp.1277-1284
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• 2015

In this paper, 1-axis tracking mechanism of solar-cell panel, which is able to rotate from -90 degree to +90 degree for maintaining always perpendicular between solar-cell panel and sun, was analyzed. This paper propose the non-linear shaped guidance and analyze mathematical formulation of non-linear shape. This analysis shows that it is able to identify the non-linear shaped guidance. Especially, even though the length of rotating link have changed, the non-linear shaped guidance could be confirm with proper size. As effectiveness of this result, 10% efficiency rising is estimated compared to the conventional 1-axis tracking mechanism and also optimal non-linear shaped guidance can be suggested for various size of solar-cell panel. Therefore the flexible mass-production is possible for various size of non-linear shaped guidance.

• Journal of the Korean Applied Science and Technology
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• v.37 no.5
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• pp.1268-1284
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• 2020

The purpose of this study was to examine mediating effect of emotional intelligence on relationship between nursing students' learning engagement and academic resilience, find whether self-regulation would moderating the relationship between learning engagement and emotional intelligence. The data were collected from 277 nursing students from three colleges in J province and were analyzed with a regression analysis and bootstrapping. As a result of the study, first, the fit of the causal model between learning engagement, emotional intelligence, academic resilience and self-regulation of nursing students was found to be good, and the causal relationship between variables was predicted appropriately. Second, partially mediating effect of emotional intelligence on the path of nursing students' learning engagement affecting academic resilience. Third, self-regulation had moderating effect on learning engagement affecting emotional intelligence. Finally, the significance of this study is that the influence of various variables that can affect the academic resilience of nursing college students was verified, and in order to improve academic resilience, a strategy that considers the subjects' learning engagement, emotional intelligence, and self-regulation.

• Journal of Korean Academy of Nursing
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• v.29 no.6
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• pp.1284-1293
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• 1999

This study was designed to investigate the effect of aromatherapy on skin xerosis and pruritus in patients undergoing maintenance hemodialysis. Twenty one subjects of this study were selected from St. Paul's Hosipital in Seoul. All the subjects were received the mineral oil massage at the arm without fistular three timesper week for 4 weeks. After 2 weeks period of wash-out, the subjects were received the aromatherapy of lavender and tea tree essence oil in the same way. This study was carried out from March 20 to June 13, 1998. Pruritus score, skin pH and stratum corneum hydration were measured before and after each treatment. But, biochemical parameters were measured before the treatment of the mineral oil massage, after the treatment of the mineral oil massage and the aromatherapy. Data of this study were analyzed by paired t-test, repeated measures ANOVA, Bonferroni multiple comparisons and Pearson correlation coefficient. The results were as follows ; 1. Pruritus score was significantly decreased after the aromatherapy, while no significant change after the treatment of the mineral oil massage. Therefore, there was a significant difference in the priritus score between the two treatments. 2. Stratum corneum hydration was significantly increased after the aromatherapy, while no significant change after the treatment of the mineral oil massage. Therefore, there was a significant difference in the stratum corneum hydration between the two treatments. 3. Skin pH was significantly increased after the treatment of the mineral oil massage, while no significant change after the aromatherapy. Therefore, there was no significant difference in the skin pH between the two treatments.4. After the aromatherapy, the serum calcium was significantly increased. Whereas the serum parathyroid hormone intact was significantly decreased compared with the treatment of the mineral oil massage. But the level of the serum Ca and PTH-intact were within the normal range. 5. Stratum corneum hydration was decreased corresponding to the duration of hemodialysis, while pruritus score and skin pH showed no change corresponding to the duration of hemodialysis and the age of the subjects. The correlation of pruritus score on skin pH, stratum corneum hydration and biochemical parameters was not significant. In conclusion, this findings indicate that aromatherapy may be effective in decreasing skin xerosis and pruritus score in uremic pruritus patients undergoing maintenance hemodialysis.

• The Journal of Pediatrics of Korean Medicine
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• v.25 no.2
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• pp.55-72
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• 2011

Objectives: The purpose of this study is to investigate clinical features of children and adolescents patients admitted to the oriental medical hospital. Methods: The study composed of 1284 inpatients aging from 0 to 19 who had been admitted in 4 oriental medical hospitals located in Daejeon and Chungcheong. Results: 1. In this study, 688 boys and 715 girls were examined, giving the ratio of 0.96:1. Average age of the children and adolescents was 11.5, and the number of inpatients has increased as getting older. 2. The percentage of children and adolescents inpatients has increased every year : 9.1% in 2005, 13.0% in 2006, 13.8% in 2007, 16.3% in 2008, 18.0% in 2009, with 22.2% in 2010, 7.8% until May 2011. The month scored the highest admittance was December and the lowest was March. 3. In systemic division, the musculoskeletal system was the most common, followed by neuromuscular system, respiratory system, digestive system, psychological system, and nervous system. 4. Most patients have admitted in acupuncture & moxibustion department, followed by oriental pediatrics, oriental rehabilitation medicine. 5. In Pediatrics, 196 boys and 166 girls were admitted. The age distribution showed that 6.4% were in infancy, 43.6% in preschool period, 30.1% in prepuberal period, 18.8% in early puberty and 1.1% in late puberty. The percentage of pediatrics inpatients has increased every year. Conclusions: More data of patients should be collated for further study. More detailed study with different kinds of diseases are expected based on this study.

• Journal of The Korean Association For Science Education
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• v.33 no.7
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• pp.1273-1284
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• 2013

The purpose of this study was to analyze the examples represented in school science textbooks by the function types for students' scientific conceptions. According to the framework of analysis, we selected lacking examples in the textbooks, and developed a questionnaire for students. The questionnaire was applied to 157 third grade students to survey their conceptions related to matter states and change of states. The ratio of students' scientific conceptions related to solid the state was high because distinct examples were represented in the textbook. However, the ratios of students' scientific conceptions related to the liquid and gas states were low because there were no distinct examples in the science textbook. Contrast examples and expansive examples of liquid and gas such as fog and steam need to be represented in science textbooks in order to help students construct scientific conceptions of matter states and change of states.

• Journal of the Korean Dietetic Association
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• v.12 no.1
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• pp.44-54
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• 2006

The study was conducted to assess the energy expenditure of 102 elementary school children. Body weight and height were measured and one-day activity diaries were collected by interviewing with children. The children spent about 9 hours 14 minutes sleeping ; 3 hours 40 minutes resting. They spent 86.4% of 24 hours (one day) in 'very light activities' and 13.3% in 'light activities'. Activity coefficient (1.41$\pm$0.11) of boys was significantly higher than that of girls(1.35$\pm$0.07). Activity coefficient (1.41$\pm$0.11) of 4th grade elementary school children was higher than those of 2nd and 6th grade school children(p<0.05). Resting energy expenditure estimated by Harris-Benedict formula, formula based on body surface area and DRI formula for Koreans were 1240.9$\pm$147.4kcal/day, 1386.5$\pm$206.9kcal/day and 1284.5$\pm$199.8 kcal/day. And daily energy expenditure by using Harris-Benedict formula, body surface area formula and DRI formula were 1708.4$\pm$258.8kcal, 1909.8$\pm$341.8kcal and 1771.1$\pm$341.9kcal/day. These results suggested that nutrition and exercise program to increase the energy expenditures of primary school children should be developed.

• Journal of Korea Technology Innovation Society
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• v.14 no.spc
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• pp.1256-1284
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• 2011

Although a existing consumer market have been studied in depth in the new technology product market, the market research on the overall level of value chain to consist of consumers, distributors, and manufacturers is weak. Therefore, in this paper consumers' purchase of new technology products were simulated and analyzed by a consumer selection model and a multi-agent model, which consist of consumers, distributors and manufacturers. Our research was focused on customer preference study in new technology product market by using conjoint analysis and discrete choice model. And changes in consumer behavior based on adoption of new technologies and offering of incentives were analyzed by ABM (Agent-based Model). In conclusion, the market share of technology products was risen when provision of incentives corresponding to inventory level and demand for new technology products occurred at the same time.