• Analytical Science and Technology
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• v.26 no.1
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• pp.80-85
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• 2013

The sixty nine accident preparedness substances (APS) having high probability of chemical accident are controlled under the Toxic Chemicals Control Act (TCCA). Around the world, there has been a growing interest in the analysis of chemical warfare agent (CWAs). When a chemical accident occurs, it is generally required to detect and identify APS. However, the quantitative analytical data remain limited in Korea. In this study, an analytical method using GC/MS for volatile organic chemicals was established and a quantitative analysis method was studied. The calibration curve for 25 chemicals were obtained and 21 chemicals showed higher coefficient of determination ($r^2$ >0.998).

• Korean Journal of Environmental Agriculture
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• v.30 no.1
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• pp.82-88
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• 2011

BACKGROUND: Tetracyclines (TCs) are mainly regulated as parent compounds by bioactivity-based screening methods in food. Especially with respect to antimicrobial residues, their metabolites/epimers are also highly concerning chemicals and traditionally applied microbial detection methods are needed to improve with validation for regulatory control. METHODS AND RESULTS: Detection capability and biological activity of tetracycline (TC), chlortetracycline (CTC), oxytetracycline (OTC) and their epimers; anhydrotetracycline (ATC), epianhydrotetracycline (EATC), epitetracycline (ETC), 4-epi-chlortetracycline (ECTC), 4-epianydrochlotetra-cycline (EACTC), 4-epioxychlortetracycline (EOTC), were measured by microbial growth inhibition screening method of Korea Food Code. CONCLUSION(S): Limited detection capabilities were found, B. megarerium and B. subtilis showed for TC and CTC, and B. subtilis for OTC. Biological potency of each epimer was also presented against various microorganisms, at the level from 50% to 96%, comparing with parent TCs. It is recommended that more advanced microbial screening methods with validation are needed, and biologically active epimers are to be considered as marker residues for MRL setting of regulatory control purpose.

• Journal of the Korean Institute of Gas
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• v.17 no.6
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• pp.73-82
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• 2013

With remarkable development of industry and technology, various chemical articles are developed to improve the quality of human life, yet some of chemicals are hazardous to human and the environment. However, safety control of chemical articles such as transportation, storage, and handling is emerging as a major issue lately. The road transportation needs well-organized safety management system, especially it has high probability of accidents. In this research, we point out problems in current state and related regulation of transportation of dangerous goods to compare the regulation in UN-RTDG. In addition, we suggest the enhancement law, the plan for standardization of classification in road transportation of dangerous goods and harmonization of labeling in transportation of dangerous goods to contribute to human health and environment protection.

• Journal of the Korean Institute of Gas
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• v.3 no.1
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• pp.8-13
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• 1999

The article 49-2 of Industrial Safety Law requires that all the owners of industrial plants which contains dangerous facilities perform the process safety management. That is, this law requires the owners of industrial plants to take necessary measures to prevent fire, harmful gas leaking, explosion, and other serious accidents that could cause demage and injuries to the employees. So far, domestic chemical plants have tried to invest money and time in safety management. But, such efforts have been made only in chemical plants that were subsidiaries of large business groups. Moreover, since the economic crisis of Korea which is symbolized by the IMF bailout, small and medium size companies could not afford to invest in safety management. Their major concern is to increase productivity and thereby, survive in this crisis. The goal of this research is to develop the process safety management system that can help small and medium size companies to positively secure the process safety management. So, in developing the process safety management system, the financial and practical difficulties of such companies are fully taken into consideration.

• Clean Technology
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• v.17 no.4
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• pp.285-299
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• 2011

As one of the REACH obligations, the extended safety data sheet (eSDS) should be communicated within the supply chain under the REACH Regulation. Based on technical guidance documents published on the ECHAs website and survey of EU's recent REACH-related informations, this paper includes a study on details of how to develop exposure scenarios (ES) such as structure of ES, process of ES develpoment, standard workflows and key input data to develop ES with an introduction of eSDS concept. This paper also contains an overview on operational conditions (OCs) and risk management measures (RMMs) that are what to consider when building an ES. The structure of Chesar (Chemical Safety Assessment and Report tool) developed by European Chemicals Agency (ECHA) is studied with a review of the available exposure estimation tools for workers, environment and consumers. Case example of generic exposure scenario (GES) for organic solvent is presented. To guide Korean EU-exporting companies, their participating roles in three steps of preparing ES are addressed.

• Journal of the Society of Disaster Information
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• v.14 no.3
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• pp.360-366
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• 2018

Purpose: This study operation of Joint inter-agency Chemical Emergency Preparedness Center and contribute to the reduction of chemical accidents that occur continuously. Method: The Joint inter-agency Chemical Emergency Preparedness Center functions and Chemical accident statistics data of the ('13~'17) were utilized. Results: The number of chemical accidents is decreasing from 113 in '15, 78 in '16, 87 in '17(latest five years 469 chemical accidents). The Joint inter-agency Chemical Emergency Preparedness Center is located in the industrial complex that handling a large amount of chemical, and performs functions such as prompt response, probation & investigation, accident prevention training, safety patrol. It is believed that it contributes to the decreasing of chemical accident by local control accident prevention function. Conclusion: Decreasing the safety management according to the Chemicals control act('15.1.1). The Joint inter-agency Chemical Emergency Preparedness Center('14.1 set up manage organization), which is operated as a mission to prepare respond to chemical accidents, plays a role.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.13 no.2
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• pp.156-163
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• 2008

Luminescent bacterial toxicity test was first introduced in the early 1980s, registered as international standard method in 1998 and now widely used as a common toxicity test method. This toxicity test uses luminescent bacterium, Vibrio fischeri, originated from marine environment as a test organism. The degree of toxicity can be evaluated from the comparison of luminescent emission intensity between control and treatment groups to toxicants and materials from various environmental matrix for 30 min. This test can be carried out by using commercial products and its results are sensitive and precise. This research is on the feasibility of adopting luminescent bacterial test as a domestic standard test protocol. Using commercial products, a series of experiments were conducted to identify the precision and accuracy of injection volume and light emission, and to evaluate concentration-response relationship between chemical concentrations and light emissions. Also, the feasibility of the application to environmental media and quality assurance/quality control were checked. The results of serial toxicity tests revealed that the preliminary luminescent bacterial toxicity test was robust and suitable as a standard method.

• Journal of the Society of Disaster Information
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• v.15 no.4
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• pp.634-647
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• 2019

Purpose: Currently, many chemicals are used in industrial and real life, and many substances are used in the form of a single substance, but most of them are used in the form of a mixture, and there is a need for a criterion for judging the danger of these substances. Method: Therefore, this study aims to confirm the risk criteria of the mixture through experimental studies on flammable mixtures in order to secure the effectiveness of the details of the existing Dangerous Goods Safety Management Act angerous Goods Judgment Criteria and to ensure the reliability and reproducibility of the dangerous goods judgment. Result: Experimental results show that alcohol flash point is mixed with water, which is a non-flammable liquid. Similar flash point trends occurred around 60% on an alcohol basis. In addition, in the case of flammable-combustible mixtures, there was little change in flash point if the flash point difference of the two materials was not large, and if the flash point difference of the two materials was low, the flash point tended to increase with the increase of the high flash point material. Conclusion: In the future, the test results may provide reference data on the experimental criteria for the flammable liquids that are cracked at the fire site.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.33 no.1 s.60
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• pp.11-15
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• 2007

Oxidation/reduction titrations are important quantitative procedures for many chemicals. Several widely used analytical methods for cosmetic ingredients are based on the redox reactions. In this article, we summarized basic theories of redox titration and applications. Determination of unsaturation properties based on iodine or bromine number, quantitation of hydrogen peroxide or peroxide materials in several cosmetic ingredients and measurement of titanium dioxide, widely used sunscreen agent, in cosmetics are discussed here.

• Fire Science and Engineering
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• v.21 no.3
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• pp.84-90
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• 2007

The UN recommends to the member of OECD to implement the GHS (Globally Harmonized System of Classification and Labelling of Chemicals) that harmonized the flammable materials for classification, labelling, production, transport, storage, handling, usage and discard. There are no significant differences between UN and GHS because GHS is based on physico-chemical hazard and acute toxity of classification and labelling of UN regulation for the classification and transportation of flammable materials. In this paper it was analyzed that the classification, labelling and test method of flammable materials for GHS and the national law of safety management of flammable materials.