• Title/Summary/Keyword: 항산화효소

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Effect of Aerobic Exercise with Resistance Exercise Programs on Blood MDA and SOD, GPx Activities in Elderly Women (유산소 운동을 병행한 근 저항성 운동이 노인 여성의 혈중 MDA 및 SOD, GPx 활성에 미치는 영향)

  • Nan, Sang-Nam;Kim, Jong-Hyuck;Ji, Min-Cheul
    • The Journal of the Korea Contents Association
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    • v.9 no.11
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    • pp.391-398
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    • 2009
  • The purpose of this study was to investigate the effects of aerobic exercise(folk dance) with resistance exercise(elastic band) for 12 weeks on blood MDA concentration and SOD GPx activities in the elderly women. The subjects consisted 12 elderly women between 65-75 years exercise were folk dance(HRmax 50-60% levels, 60min, two per a week) and elastic band(yellow band, 60min, two per a week) program for 12 weeks. SOD, GPx activities in the before combined exercise were significantly increased than that in after combined exercise. These results show that aerobic exercise with resistance exercise program in considered to contribute enforced of antioxidant enzyme system by increased SOD and GPx activities in elderly women.

Effects of Fermented Mulberry Leaves (Morus alba L.) on Oxidative Modification of Antioxidnat Enzymes (항산화 효소의 산화적 변형에 뽕잎 발효물이 미치는 영향)

  • Kang, Jung Hoon
    • Journal of the Korean Applied Science and Technology
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    • v.36 no.3
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    • pp.985-994
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    • 2019
  • Muberry (Morus alba L.) leaves fermented with Hericium erinaceum mycelium (MA-HE) were assessed for the protection against oxidative modification of antioxidant enzymes, Cu,Zn-superoxide dismutase(SOD) and ceruloplasmin(CP). MA-HE were shown to significantly inhibited oxidative modifications and inactivations of Cu,Zn-SOD and CP induced by peroxyl radical. Antioxidant activity of MA-HE evaluated using peroxyl radical scavenging assays. MA-HE showed 44.03% of peroxyl radical scavenging activity at $100{\mu}g/mL$. Thus, MA-HE protect the antioxidant enzymes from oxidative damage by the scavenging peroxyl radicals. The results suggested that MA-HE was effectively removed reactive oxygen species in cells, thereby protecting cytotoxicity caused by oxidative stress.

Thermal effects on antioxidant enzymes response in Tilapia, Oreochromis niloticus exposed Arsenic (Arsenic에 노출된 틸라피아, Oreochromis niloticus의 항산화 효소반응에 미치는 수온의 영향)

  • Min, EunYoung;Jeong, Ji Won;Kang, Ju-Chan
    • Journal of fish pathology
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    • v.27 no.2
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    • pp.115-125
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    • 2014
  • The effects of waterborne arsenic (As) exposure on antioxidant defense were studied in liver and gills of tilapia, Oreochromis niloticus under thermal stress. Tilapia were exposed to different As concentrations (0, 200 and $400{\mu}g/L$) at three water-temperatures (WT; 20, 25 and $30^{\circ}C$) for 10 days. In antioxidant response, glutathione (GSH) levels, glutathione reductase (GR), glutathione peroxidase (GPx) and glutathione S-treansferase (GST) activities were significantly decreased depend on WT in the gills after As exposure. Also, the range of fluctuation in these enzymes activities was most significantly increased at $30^{\circ}C$ in the liver of tilapia exposed to As. The present findings suggest that a simultaneous stress by temperature change and As exposure could accelerate the alteration in antioxidant enzymes activities of tilapia.

A Study on Enzyme Activity and Antioxidant Activity of Fermented Rice Bran of Saccharomycopsis fibuligera Isolated from Nuruk (누룩에서 분리한 Saccharomycopsis fibuligera 미강발효물의 효소활성 및 항산화능에 대한 연구)

  • Park, Yong-Won
    • Journal of the Korea Convergence Society
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    • v.12 no.11
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    • pp.403-410
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    • 2021
  • This paper aimed to increase the functionality and competitiveness of rice bran, which is used as an alternative food and cosmetic raw material, through fermentation. As a result of comparing the enzyme activity of 𝛼-amylase, CMCase, 𝛽-glucosidase, protease, etc. of fermented rice bran using standard strains with 6 strains with excellent enzyme activity among 50 strains of Saccharomycopsis fibuligera isolated from 5 types of Nuruk, A8 strain showed excellent enzyme activity of 13.7%, 21.1%, 50.3%, and 10.0% compared to the KCTC 7806 strain. As a result of the ABTS and DPPH tests as a result of fermentation, it was confirmed that rice bran fermented with A8 had 1.12 times and 1.28 times more antioxidant activity than rice bran fermented with KCTC 7806 strain. In this paper, it was possible to confirm the S. fibuligera A8 strain superior to the standard S. fibuligera strain KCTC 7806.

Differences in Body Weight, Dietary Efficiency, Brain Obesity Control Factor (AMPK), Reactive Oxygen Species (MDA), and Antioxidant Enzymes (SOD) in Young Mice According to the Intensity of Aerobic Exercise for 8 Weeks (8주간의 유산소 운동강도에 따른 어린 생쥐의 체중, 식이효율, 뇌의 비만조절 인자(AMPK), 활성산소(MDA), 항산화효소(SOD)의 차이)

  • Jeon, Mi Yang
    • Journal of Korean Biological Nursing Science
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    • v.23 no.3
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    • pp.247-255
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    • 2021
  • Purpose: The goal of this study was to see how different aerobic exercise intensities affected AMP-activated protein kinase (AMPK), reactive oxygen, and antioxidant enzymes in young mice during an 8-week period. Methods: Forty male C57BL/6 mice, aged seven weeks, were randomly assigned to one of four groups: control (n=10), low-intensity exercise (n=10), moderate-intensity exercise (n=10), and high-intensity exercise (n=10). For eight weeks, aerobic activity was performed once a day for 35-40 minutes, five days a week. The data were analyzed using descriptive statistics, analysis of variance (ANOVA), chi-squared tests, and the Tukey test in the SPSS/WIN 25.0 program. Results: Weight (p=.001) was substantially different between the moderate-intensity exercise group and the control group in AMPK (p<.001). In addition, there were no significant differences between the moderate-intensity exercise group and the control group in reactive oxygen malondialdehyde (MDA) levels (p=.136) and antioxidant enzyme superoxide dismutase (SOD) levels (p=.521). Conclusion: These findings suggest that moderate-intensity aerobic exercise increased AMPK activation and helped young mice shed weight.

The Oxidative Stress Induction and Response of Antioxidative Enzymes in the Large Patch-Infected Zoysiagrass II. Activity of antioxidative enzymes (라지 팻치에 감염된 잔디의 산화적 스트레스 발현과 항산화효소의 활력의 변화 II. 항산화효소의 활력)

  • Kim, Dae-Hyun;Lee, Bok-Rye;Li, Ming;Kim, Tae-Hwan
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.27 no.2
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    • pp.137-144
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    • 2007
  • To investigate the effect of large patch infection on oxidative stress induction, super-oxide dismutase (SOD), catalase (CAT) and peroxidase (POD) were compared between pathogen-infected and healthy (control) zoysiagrass. The sampling for leaves and roots were carried out every 2 days for a period of 6 days. The SOD activity was not significantly affected by pathogen-infection until day 2, but significant increase of both leaves (+48%) and roots (+49%) were observed at day 6 compared with control. The CAT activity was remarkedly increased by +25% in leaves and +101% in roots within the first 2 days and then rapidly decreased. The POD activity in pathogen-infected leaves was significantly increased by 74% at day 6. The increase of POD activity in pathogen-infected roots was 2-fold higher than that of the control at day 6. These results indicated that large patch-infection induce oxidative stress, and that SOD-CAT-POD antioxidant system of zoysiagrass was effectively operated.

항산화효소 유전자 도입형질전환 담배의 수분스트레스에 대한 반응

  • 박용목;곽상수
    • Proceedings of the Korean Environmental Sciences Society Conference
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    • 2003.11b
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    • pp.231-232
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    • 2003
  • 환경스트레스에 대한 내성식물의 개발의 일환으로 항산화 유전자를 도입한 형질전환 식물체를 이용하여 수분스트레스에 대한 반응성을 비형질전환 식물체와 비교하였다. 심한 수분스트레스를 유도하였을 때, 비형질전환 식물체에 비해 형질전환 식물체가 저하하는 수분포텐셜에 대해 높은 기공전도도와 광합성 능력을 가진 것으로 나타났다.

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Skin aging and Antioxidants (피부노화와 항산화제)

  • 박수남
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.23 no.1
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    • pp.75-132
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    • 1997
  • 피부는 항시 산소와 접촉하고 있고 자오선 조사에 크게 노출되어 있다. 따라서, 활성산소종으로 유도된 피부의 광산화적 손상 위험이 실질적으로 증가하고 있다. 활성산소종이란 한 무리로서 수퍼옥사이드 음이온과 히드록실 라디칼과 같은 산소 중심의 라디칼을 포함할 뿐만 아니라, 과산화수소나 싱글렛 옥시전과 같은 몇 종류의 비라디칼종들, 그 외의 다른 것으로, 활성산소종과 생체 성분과의 반응으로 유래된 과산화 라디칼, 알콕실 라디칼, 히드로과산화물 식세포에서 살균작용을 나타내는 HOCl등을 포함한다. 피부에는 복잡한 항산화 방어망이 발달되어 활성산소종에 대항하여 보호작용을 한다. SOD, 카탈라아제, 글루타치온퍼옥시다제 등의 항산화효소와 $\alpha$-토코페롤, 아스코르브산, 카로티노이드 등의 비효소적 항산화 물질들이 피부 항산화 방어망을 구축하고 있다. 그러나 계속된 자외선에의 노출로 생성된 과잉의 활성산소종은 실질직으로 피부의 효소적 그리고 비효소적 항산화 방어를 위태롭게 한다. 따라서 균형은 산화상태 쪽으로 유리하게 기울어진다 결과적으로 산화적 스트레스는 세포 성분들에 대한 손상을 야기시킨다. 지질 과산화, 단백질 산화, 탄력 섬유인 콜라겐과 엘라스틴의 사슬절단 밀 비장성적인 교차결합, 히아루론산 사슬의 절단, 멜라닌 생성반응 촉진, DNA 산화와 같은 생체 구성 성분들의 손상이 일어난다. 결국에는 탄력감소, 주름살 및 기미, 주근깨 등으로 특징 지워지는 피부노화가 가속화된다. 따라서 필요한 항상화제를 함유한 식품이나 화장품을 통한 계속적인 항산화제 보충으로 피부 항산화 방어망을 견고히 할 때 피부노화는 지연되고 억제될 것이다.주거를 구분하고 있는 것으로 조사되었으나, 아직까지 절반 가량(52.2%)의 상점들이 다른 사람 소유의 건물을 전 ·월세로 임대하여 사용하고 있음을 알 수 있었다. 이상에서 살펴본 바와 같이 고수동굴 주변의 상업적 특성은 90년대에 들어서면서 자기 고장에 있는 관광자원을 내 고향의 자랑거리로 생각하고 이를 지역발전의 밑거름으로 활용하고자 하는 인식이 늘어나고 있음을 알 수 있었다. 그러나, 관광지로서의 특성이라 할 수 있는 다른 관광동굴과의 차별성이 부족하다고 할 수 있다. 즉 다른 지역의 기념품점에서 구입할 수 없는 고수동굴만이 갖고 있는 특징적인 기념품을 판매함으로써 관광객의 구매욕구를 높인다거나 고수동굴의 일주관광 후 관광객을 좀 더 머무르게 할 수 있는 시설의 개발이 더 필요하다.유의한 차이를 나타내는 항목이 많았으며 12주에서 vehicle과 유의적인 차이를 나타내는 항목도 많으므로 3-APPA가 APSA 보다 광범위한 피부노화 억제 효과를 갖는 물질이라고 할 수 있다.주도적 역할을 수행해야 할 것이다. 넷째, 선박금융제도의 개선과 신금융상품의 개발이 요구된다. 내수 수요인 계획조선의 지원조건을 개선하고 연불수출자금을 BBC자금으로 활용토록하여 국내 선주들의 신조를 유도해야 할 것이다. 그 외에 향후 금융개방화에 맞추어 해외자금을 활용한 리스금융, 상사금융 등의 민간신용제도를 더욱 활성화하고 선진국의 선박금융기법에 대한 연구 및 도입 등 선주들에게 다양한 선박건조자금을 제공하여 내수기반 확충에도 노력해야 할 것 이다.있었다., 인삼이 성장될 때 부분적인 영양상태의 불충분이나 기후 등에 따른 영향을 받을 수 있기 때문에 앞으로 이에 대한 많은 연구가

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Antioxidative Activity of Pine (Pinus densiflora) Needle Extracts in Rats Fed High-Cholesterol Diet (고콜레스테롤 식이 섭취 흰쥐에 대한 적송잎 추출물의 항산화 효과)

  • Kang, Sung-Rim;Shin, Mee-Ok;Kim, Sung-Gu;Lee, Sang-Hyeon;Kim, Mi-Hyang
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.4
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    • pp.423-429
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    • 2009
  • This study was conducted to investigate the effects of pine (Pinus densiflora) needle extracts on hepatic antioxidative system in rats fed high-cholesterol diet. Eight-week old Sprague Dawley rats were divided into four groups; normal diet group (CON), 0.5% cholesterol diet group (0.5% CHOL), 0.5% cholesterol diet and pine needle extracts prepared by using hot water group (HOT water), and 0.5% cholesterol diet and pine needle extracts prepared by using sub-supercritical $CO_2$ group (Sub-supercritical). The serum ALP, AST, and ALT activities were increased by 0.5% cholesterol diet supplementation, but treatment with pine needle extracts showed decrease compared with 0.5% CHOL group. The SOD activity in liver at 0.5% cholesterol diet group was more decreased than control group while Sub-supercritical group had significantly higher SOD activity than 0.5% CHOL group. Moreover, groups with pine needle extracts supplementation had higher level of GPx in liver than 0.5% cholesterol diet group. These results suggest that pine needle extracts increased antioxidative activities.

Enhancement of Photosynthetic Characteristics and Antioxidant Enzyme Activities on Chili Pepper Plants by Salicylic Acid Foliar Application under High Temperature and Drought Stress Conditions (고온 및 건조 스트레스 조건 하에서 살리실산 경엽처리에 의한 고추의 광합성 특성 및 항산화효소 활성 증대)

  • Lee, Jinhyoung;Lee, Heeju;Wi, Seunghwan;Lee, Hyejin;Choi, Haksoon;Nam, Chunwoo;Jang, Seonghoe
    • Journal of Bio-Environment Control
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    • v.31 no.4
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    • pp.311-318
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    • 2022
  • Salicylic acid (SA), a phenolic compound, plays a pivotal role in regulating a wide range of physiological and metabolic processes in plants such as antioxidant cellular defense, photosynthesis, and biotic and abiotic stress responses during the growth and development. We examined the effect of exogenous SA application (100 mg·L-1) on the growth, yield, photosynthetic characteristics, lipid peroxidation, and antioxidant enzyme activity of chili pepper plants under high temperature and drought stress conditions. SA treatment induced increases of net photosynthetic rate (Pn), stomatal conductance (Gs) and transpiration rate (Tr) under the stress condition with the highest level after the third treatment. The contents of malondialdehyde and H2O2 were significantly lower in the third treatment of SA compared to the control. The activity of ascorbate peroxidase, catalase, peroxidase and superoxide dismutase, increased in treated plants by up to 247, 318, 55 and 54%, respectively compared to the nontreated control. There was no significant difference in the growth characteristics between SA-treated and nontreated plants, while the SA treatment increased marketable yield (kg/10a) by about 15% compared to the nontreated control. Taken together, these results suggest that foliar application of SA alleviates physiological damages caused by the combination of drought and heat stress, and enhances the photosynthetic capacity and antioxidant enzyme activities, thereby improving tolerance to a combination of water deficit and heat stress in chili pepper plants.