• Food Science and Industry
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• v.40 no.2
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• pp.46-58
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• 2007

제2형 당뇨병은 대사성 질환으로 간, 근육 그리고 지방 조직 세포에서 인슐린 작용의 장애로 나타나는 인슐린 저항성으로 혈당의 이용이 감소하여 혈당이 높아짐에도 불구하고 췌장의 베타세포에서 인슐린 분비가 충분하지 못할 때 유발된다. 서구에서는 비만 등으로 인해 인슐린 저항성이 증가하면 인슐린 분비가 높은 고인슐린혈증을 나타내어 당뇨병으로의 진전은 늦다. 하지만 우리나라를 비롯한 아시아의 사람들은 인슐린 저항성이 증가할 때 인슐린 분비가 충분치 못해 혈청 인슐린 농도가 정상인과 비슷하거나 더 낮은 상태에서 당뇨병으로 진전된다. 이러한 차이는 우리나라를 비롯한 아시아 사람들에게서 제2형 당뇨병의 발생이 급격하게 증가할 것이라는 보고되었다. 결국 당뇨병은 간, 근육 및 지방조직에서의 인슐린 작용의 장애와 췌장의 베타세포에서 인슐린 분비의 부족의 복합적인 장애에 의해서 나타나고 이것은 공통적으로 각 조직에서의 인슐린/insulin growth factor (IGF)-1 신호전달의 장애와 관련이 있다. 베타세포에서의 인슐린분비 자체는 인슐린/IGF-1 신호전달과 관계가 없지만 간접적으로 관련이 있다. 인슐린 분비능은 베타세포의 증식과 생존에 의한 베타세포의 양과 밀접한 관련이 있는데 인슐린/IGF-1 신호전달은 베타세포의 증식과 생존을 조절한다. 그러므로 혈당 조절에 관여하는 기능성 식품은 인슐린 작용을 향상시키는 인슐린 민감성 특성을 가지거나, 혈당이 높아질 때 인슐린 분비를 촉진시키는 insulinotropic 작용을 하는 성질을 가지고 있어야 하겠다. 전자의 대표적인 약은 1999년에 미국 FDA에서 승인 받은 peroxisome proliferator-activated receptor $(PPAR)-{\gamma}$ agonist 인 thiazolidinedione 계통의 약물인 troglitazone, pioglitazone, rosiglitazone 등이 있고, 후자는 2007년에 승인 받은 Exenatide는 glucagon like peptide (GLP)-1 agonist이다. 이 두 가지 약은 모두 자연계에 존재하는 동식물에서 유래된 것으로 식품에도 많이 다양한 종류의 인슐린 민감성 물질이나 insulinotropic 작용을 하는 물질이 함유되어 있을 것이다. 이러한 기능 이외에 혈당조절 약이나 식품으로 사용되는 것은 탄수화물의 소화를 방해하는 것으로 탄수화물 소화효소인 a-amylase 또는 maltase의 활성을 억제하여 식후 혈당의 급격한 상승을 방지하는 것이 있다. 우리나라 사람들은 탄수화물의 섭취가 너무 많아서 실제로 이러한 식품이나 약의 효능이 높지 않을 것이다. 혈당을 조절하는 기능성 식품은 이 세 가지 효능 중 일부를 가지고 있는 것이 될 수 있다. 이러한 기능을 스크리닝하기 위해서 3가지 단계를 거쳐야 한다. 먼저 시험관에서 또는 세포 실험을 통해서 앞서 언급한 3가지 기능을 가지고 있는 지 여부를 각각 조사한다. 이중에서 효과가 있는 것은 당뇨 동물 모델을 사용하여 in vivo에서 혈당 강하기능과 혈당 강하기전을 조사하는 실험을 한다. 효과가 있는 식품이 우리가 전통적으로 식품으로 섭취해 왔다면 독성 검사를 거쳐야 할 필요가 없지만 한약재이거나 특수 식품의 경우에는 in vivo 실험 전에 GLP 기관에서 반드시 독성 실험을 거쳐 독성 유무를 확인할 필요가 있다. 동물 실험에서 효과적인 것은 인체 실험을 거쳐 혈당 조절 기능성 식품으로 식약청에서 허가를 받을 수 있겠다. 결론적으로 식품에는 항당뇨 특성을 가진 물질들이 함유되어 있는 것들이 상당히 많다. 혈당 조절기능이 있는 기능성 식품으로 개발할 때 고려해야 할 것은 1) 그 양이 혈당 강하 기능성 식품으로 지정받을 수 있을 정도로 충분히 함유되어 있느냐, 2) 혈당을 강하시키는 기전이 단순히 당의 배설을 촉진시켜서 혈당을 저하시키는 것이 아니라, 인슐린 작용을 촉진시키거나, 포도당 자극에 의한 인슐린 분비를 촉진시키거나 탄수화물의 소화 흡수를 억제시킴으로 혈당을 강하시키는 지 등을 파악하는 것이다. 이러한 조건을 만족시키는 식품은 지속적으로 섭취할 때 당뇨병을 예방하거나 진전을 지연시킬 수 있는 혈당조절기능이 있는 기능성 식품으로 개발 가능성이 있겠다.

• Journal of Korea Port Economic Association
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• v.40 no.2
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• pp.205-219
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• 2024

This study assesses Incheon Metropolitan City's potential as a global logistics hub amid intensified competition since the 2000s. Utilizing Importance-Performance Analysis(IPA), it evaluates competitive factors for logistics hub cities and Incheon's current positioning. The research identifies world-class infrastructure development and global city connectivity as key competitiveness factors. While Incheon, with its international airport and port, currently functions as a logistics hub, areas for improvement emerge. Recommendations include developing specialized cargo infrastructure for cold-chain and e-commerce, expanding the global network through multimodal transportation, and addressing gaps in smart and eco-friendly logistics. These suggestions encompass professional training, information platform establishment, and sector-wide decarbonization initiatives. The study's significance lies in its IPA-driven evaluation of competitiveness factors and Incheon's status, providing actionable recommendations for strategic planning to enhance the city's position as a global logistics hub.

• The Journal of the Korea institute of electronic communication sciences
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• v.10 no.8
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• pp.953-958
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• 2015

Generally, Urban railway have special characteristics with short distance journey and minimum headway intercity transportation. These days, urban railway operators choose the driverless operation system without driver. On the contrary, Conventional & high speed railway utilize for long distance and high speed running. Because of special conditions of freight railway operation compared with urban railway, operation of conventional & high speed railway is showed very different characteristics. In this paper, We compares different operation scheme of urban railway and conventional & high speed railway and then present condition for train control system based on radio.

• Applied Chemistry for Engineering
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• v.32 no.6
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• pp.695-699
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• 2021

In this study, Selective Catalytic Reduction on Diesel Particulate Filter (SDPF) after-treatment system was introduced to simultaneously remove NO_x and Particulate Matters (PM) emitted from trucks and special cargo vehicles using old engine. First, in order to select an Selective Catalytic Reduction (SCR) catalyst for SDPF, the de-NO_x performance of V/TiO₂ and Cu-Zeolite catalysts were compared, and the SCR catalyst characteristics were analyzed through Brunauer Emmett Teller (BET), X-ray Diffraction (XRD) and NH3-TPD (Temperature Programmed Desorption). From the activity test results, the Cu-zeolite catalyst showed the best thermal stability. For optimal coating of SDPF, slurry was prepared according to the target particle size. From the coating stability and back pressure test results of SDPF according to the amount of SCR coating, As a result of comparing coating stability, back pressure, and de-NOx performance by producing A, B, and C samples for each loading amount of the SDPF catalyst, the best results were found in the B sample. The engine dynamometer test was conducted for the optimal SDPF after-treatment system, and the test results satisfied Eu-5 regulations.

• International Area Studies Review
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• v.12 no.3
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• pp.467-492
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• 2008

This paper analyzes the specific product-basis trade structure between Busan and Japan using the recent 2000-2007 trade statistical data. Several specific product-basis trade structure tests such as intra-industry trade index and market comparative advantage index show that there are considerable differences in intra-industry trade structure between Busan and Japan. Furthermore, this paper found that Busan has high quality vertical intra-industry trade and horizontal intra-industry trade as well as low quality vertical intra-industry trade in trading with Japan. While Busan has the market comparative disadvantage in automobile-part products in Japan. This paper also examines the contribution to trade balance of Busan's exports and the movement of Busan's comparative advantage patterns in Japan. The comparative advantage appears to have overall stability and convergence properties using symmetric indices.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.24 no.8
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• pp.1095-1101
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• 2020

Vessels or aircraft should be loaded with containers or cargo to maintain weight balance in order to be stable when navigating the route. The container loading algorithm is known as the NP problem and several heuristic methods have been studied. Containers can be characterized by the uniform volume and weight, which makes it easier to find an optimal loading method. In this paper, we propose an algorithm for weight balance when the volume and weight of an object are uniform. It is assumed that the loading space has a special structure of m * n mesh (where m and n are both odd). In this case, we designed a greedy algorithm and proved that the algorithm is optimal in that it can always find a loading position that maintains a weight balance regardless of the number of objects. Our algorithm can be used in many engineering problems, such as loading algorithms and load balancing problems.

• Journal of the Korea Society of Computer and Information
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• v.25 no.12
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• pp.261-270
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• 2020

In this study, we identify promising technologies for Piggyback transportation system by analyzing the relevant patent information. In order for this, we first develop the patent database by extracting relevant technology keywords from the pioneering research papers for the Piggyback flactcar system. We then employed textmining to identify the frequently referred words from the patent database, and using these words, we applied the LDA (Latent Dirichlet Allocation) algorithm in order to identify "topics" that are corresponding to "key" technologies for the Piggyback system. Finally, we employ the ARIMA model to forecast the trends of these "key" technologies for technology forecasting, and identify the promising technologies for the Piggyback system. with keyword search method the patent analysis. The results show that data-driven integrated management system, operation planning system and special cargo (especially fluid and gas) handling/storage technologies are identified to be the "key" promising technolgies for the future of the Piggyback system, and data reception/analysis techniques must be developed in order to improve the system performance. The proposed procedure and analysis method provides useful insights to develop the R&D strategy and the technology roadmap for the Piggyback system.

• Journal of Navigation and Port Research
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• v.44 no.6
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• pp.534-540
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• 2020

Like most developed countries, South Korea is experiencing a severe lack of seafarers. Because young people's demands for a high quality of life has led them to seek shore-based careers. The wage difference between seafaring and shore-based careers has been decreasing gradually, however South Korea's unique Boarding Service Reserve System Policy has helped recruit and retain young sailors and, since 2017, the government has focused on creating new jobs and stabilizing the status of irregular workers in both private and public sectors. It specifically established the Economic, Social & Labor Council to carefully analyze seafarers' employment stability, which previously had been overlooked in the country. This research used the Binary Logit Model (BLM) to analyze the determinants of seafarers' employment stability in both permanent and non-permanent positions. We found that seafarers' employment stability correlated highly with their education level. This means that seafarers who graduated from the above mentioned two maritime universities would have more job stablity than those who graduated from maritime high schools or general universities. Other independent variables, such as the shipping company, vessel, hip management companies, work assignment, rank, and license had no significant impact on employment stability.

• Smart Media Journal
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• v.13 no.1
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• pp.60-66
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• 2024

The Internet of Things, which began by connecting sensors through a network, is developing into an intelligent IoT by combining it with artificial intelligence technology. Elevators are essential for high-rise buildings in the city, and elevators move from floor to floor and perform the functions of transporting goods and moving users. It is necessary to provide safe and convenient services for elevator users in high-rise buildings or special environments (hospitals, etc.). In an environment where rapid patient transportation is important, such as large hospitals, there is a problem that hospital staff and the general public often use the elevator for patients. In particular, when moving patients where golden time is important, the waiting time to board the elevator is a major hindrance. In order to solve this problem, this study proposes an intelligent IoT system for elevator calling using smartphone Bluetooth. First, we experimented with the elevator calling IoT system using smartphone Bluetooth, and as a result of the experiment, it was confirmed that it can authenticate elevator users and reduce unnecessary waiting time for boarding. In addition, we propose an intelligent IoT system that connects with intelligent IoT.

• Korean Journal of Food Science and Technology
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• v.5 no.2
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• pp.113-118
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• 1973

In this study, the several chemical compositions, which include general components (moisture, fat, protein, sugar, fiber, ash, acid insoluble ash), minor components (sesamol, sesamolin, sesamin), the characteristics of oil (specific gravity, refractive index, iodine value, saponification value, unsaponificable matter, insoluble impurities), fatty acid components (analyzed by GLC), amino acid patterns (analyzed by autoanalyzer), of Korean whole white Sesamum indicum were investigated and were compared with decuticled sesame samples. The results were summarized as follows: 1) The crude fiber, total ash and acid insoluble ash contents of the decuticled sesame seed and it meal were significantly lower as compared to the whole sesame samples. 2) The specific gravity, refractive index, iodine value, unsaponificable matter and insoluble impurities contents of the whole sesame oil were greater than the decuticled samples. 3) The fatty acid contents of the whole and decuticled sesame oil were approximatly equal amounts. But unsaturated fatty acid contents of the decuticled sesame oil was significantly lower than the whole sesame oil. 4) The decuticled sasame meal was concentrated higher protein than the whole sasame meal. But amino acid contents of the protein in their was approximatly equal amounts and sesame proteins are found to be rich in methionine, cystine and tryptophan, they are deficient in lysine. 5) The sesamol, sesamolin and sesamin contents of the whole and decuticled sesame oil were approximatly equal amounts. 6) The oxalate and calcium contents of the decuticled sesame seed and its meal were also significantly lower as compared to the whole sesame samples.