• Title/Summary/Keyword: 지연 모델

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Effect of MK-801 on the Prevention and Treatment of Tardive Dyskinesia (지연성 운동장애의 예방과 치료에 대한 MK-801의 효과)

  • Seo, Jeong-Soo;Chung, Young-Chul;Park, Keun-Young;Eun, Hong-Bai;Kim, Young-Hyun
    • Korean Journal of Biological Psychiatry
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    • v.4 no.2
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    • pp.246-250
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    • 1997
  • Tardive dyskinesia(TD) is a serious side effect of long-term treatment with neuroleptic medications. To investigate if glutamatergic hyperfunction is associated with TD, effect of MK-801 on the prevention and treatment of TD was studied using a rat model, ie, vacuous chewing movements(VCM). When comparing VCM scores of GroupI(haldol decanoate+MK-801) with that of GroupII(haldol decanoate+phosphate buffer saline), late measured VCM scores of former were significantly lower than that of latter, meaning that MK-801 is effective in the prevention of VCM. Furthermore, when MK-801(0.1mg/kg, 0.3mg/kg) is administered to VCM(+) rats(VCM${\geq}$ 7/4min) of GroupII, VCM scores were significantly decreased, meaning that MK-801 is also effective in the treatment of VCM. From the above results, it is suggested that glutamatergic hyperfunction might be involved in the development of TD and MK-801 could be effective in the prevention and treatment of it.

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Study on the Combustion Characteristics of a Small-Scale Orimulsion Boiler (소형 오리멀젼 보일러의 연소특성 연구)

  • Kim, Hey-Suk;Shin, Mi-Soo;Jang, Dong-Soon;Choi, Young-Chan;Lee, Jae-Gu
    • Journal of Korean Society of Environmental Engineers
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    • v.27 no.10
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    • pp.1081-1089
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    • 2005
  • In order to examine the application feasibility of Orimulsion fuel in a commercial boiler using heavy fuel oil, a numerical and experimental research efforts have been made especially to figure out the fundamental combustion characteristics of this fuel in a small-scale boiler. One of the notable combustion features of Orimulsion fuel is the delayed appearance of flame location with the flame shape of rather broad distribution, which is found experimentally and confirmed by numerical calculation. This kind of flame characteristics is considered due to the high moisture content included inherently in the process of Orimulsion manufacture together with micro-explosion by the existence of fine water droplets. In order to investigate the effect on the combustion characteristics of Orimulsion, a series of parametric investigation have been made in terms of important design and operational variables such as injected amount of fuel, types of atomization fluid, and phonemenological radiation model employed in the calculation, etc. The delayed feature of peak flame can be alleviated by the adjustment of the flow rate of injected fuel and the generating features of CO, $SO_2$ and NO gases are also evaluated in the boiler. When the steam injection as atomizing fluid is used, the combustion process is stabilized with the reduced region of high flame temperature. In general, the calculation results are physically acceptable and consistent but some refinements of phenomenological models are necessary for the better resolution of pollutant formation. From the results of this small-scale Orimulsion boiler, it is believed that a number of useful information are obtained with the working computer program for the near future application of Orimulsion fuel to a conventional boiler.

Design of QDI Model Based Encoder/Decoder Circuits for Low Delay-Power Product Data Transfers in GALS Systems (GALS 시스템에서의 저비용 데이터 전송을 위한 QDI모델 기반 인코더/디코더 회로 설계)

  • Oh Myeong-Hoon
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.43 no.1 s.343
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    • pp.27-36
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    • 2006
  • Conventional delay-insensitive (DI) data encodings usually require 2N+1 wires for transferring N-bit. To reduce complexity and power dissipation of wires in designing a large scaled chip, an encoder and a decoder circuits, where N-bit data transfer can be peformed with only N+l wires, are proposed. These circuits are based on a quasi delay-insensitive (QDI) model and designed by using current-mode multiple valued logic (CMMVL). The effectiveness of the proposed data transfer mechanism is validated by comparisons with conventional data transfer mechanisms using dual-rail and 1-of-4 encodings through simulation at the 0.25 um CMOS technology. In general, simulation results with wire lengths of 4 mm or larger show that the CMMVL scheme significantly reduces delay-power product ($D{\ast}P$) values of the dual-rail encoding with data rate of 5 MHz or more and the 1-of-4 encoding with data rate of 18 MHz or more. In addition, simulation results using the buffer-inserted dual-rail and 1-of-4 encodings for high performance with the wire length of 10 mm and 32-bit data demonstrate that the proposed CMMVL scheme reduces the D*P values of the dual-rail encoding with data rate of 4 MHz or more and 1-of-4 encoding with data rate of 25 MHz or more by up to $57.7\%\;and\;17.9\%,$ respectively.

Kinetic Measurement of the Step Size of DNA Unwinding by Bacteriophage T7 DNA Helicase gp4 (T7 박테리오파지 gp4 DNA helicase에 의한 DNA unwinding에서 step size의 반응속도론적 측정)

  • Kim, Dong-Eun
    • Journal of Life Science
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    • v.14 no.1
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    • pp.131-140
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    • 2004
  • T7 bacteriophage gp4 is the replicative DNA helicase that unwinds double-stranded DNA by utilizing dTTP hydrolysis energy. The quaternary structure of the active form of T7 helicase is a hexameric ring with a central channel. Single-stranded DNA passes through the central channel of the hexameric ring as the helicase translocates $5'\rightarrow3'$ along the single-stranded DNA. The DNA unwinding was measured by rapid kinetic methods and showed a lag before the single-stranded DNA started to accumulate exponentially. This behavior was analyzed by a kinetic stepping model for the unwinding process. The observed lag phase increased as predicted by the model with increasing double-stranded DNA length. Trap DNA added in the reaction had no effect on the amplitudes of double-stranded DNA unwound, indicating that the $\tau7$ helicase is a highly processive helicase. Global fitting of the kinetic data to the stepping model provided a kinetic step size of 10-11 bp/step with a rate of $3.7 s^{-1}$ per step. Both the mechanism of DNA unwinding and dTTP hydrolysis and the coupling between the two are unaffected by temperature from $4∼37^{\circ}C$. Thus, the kinetic stepping for dsDNA unwinding is an inherent property of tile replicative DNA helicase.

A Multipath Delay Time Detection Method For $\frac{\pi}{4}$ Shift QPSK Modulation Under The Frequency Selective Fading Environment (주파수 선택성 페이딩 환경하에서 $\frac{\pi}{4}$ shift QPSK 변조방식에 대한 다중파의 시간지역 검출법 제안)

  • 조병진;김대영
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.16 no.10
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    • pp.941-950
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    • 1991
  • channel is severely degraded by multipath delay time spread. In this paper. We propose a simple multipath delay time detection method, which has a merit of in serviceable, yet simple H/W realizability for $\pi/4$ shift QPSK by detecting cross channel interference. A $\pi/4$ shift QPSK signal originally has quadrature channel(Q-ch) component. Thus in order to measure CCI between in-phase channel(I-ch) and quadrature channel(Q-ch), which closely related to multipath delay time, Frequency doubling scheme(frequency doubler) and differential detector is proposed, which makes $\pi/4$ shift QPSK signal look like BPSK and also makes it possible for CCI to be detected at I-ch detector output. To get an information from time varying I-ch output signal under the multipath lading environment, a method for obtaining the mean of the absolute value$(V_{MABS}(t))$ and another one for obtaining the root mean square value$(V_{RMS}(t))$ of CCI are proposed. Furthermore, a relationship between delay spread and CCI is also analyzed. In order to confirm theoretical results, computer simulation has been carried out under the quasi-static and Reyleigh distributed two ray multipath fading environments. A fairly good result was obtained. However it was also shown that this method is sensitive to bandwidth restriction to some extent. In addition, some idea for a simple hardware realization for the frequency doubler are given.

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Longitudinal Mediated Effects of Informal Labeling on the Relationship between Adolescent Abuse and Academic Achievement: Application of Labeling Theory with Autoregressive Cross-Lagged Modeling (청소년의 피학대경험이 학업성취에 미치는 영향에 대한 비공식낙인의 종단적 매개효과 검증: 낙인이론과 자기회귀교차지연 모델을 적용하여)

  • Taekho Lee ;Yoonsun Han
    • Korean Journal of Culture and Social Issue
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    • v.22 no.4
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    • pp.567-593
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    • 2016
  • This study examined longitudinal mediated effects of informal labeling on the relationship between adolescent abuse and academic achievement using autoregressive cross-lagged modeling. Data were obtained from the second, third, and fourth waves of the middle school student cohort (N=3,168) of the Korean Youth Panel Survey. The major longitudinal findings of this study are as follows: First, adolescent abuse was found to have a positive association with future informal labeling. Second, informal labeling was found to have a negative association with future academic achievement. Finally, the longitudinal relationship between adolescent abuse and academic achievement was partially mediated by informal labeling. Based on these results, this study suggests directions for adolescent abuse prevention. The need for education and prevention of informal labeling was discussed, as well as the direction of intervention programs for adolescents with experience of informal labeling. Furthermore, this study may provide empirical evidence for labeling theory and contribute to increasing awareness on the longitudinal influence of adolescent abuse and informal labeling.

5G Network Resource Allocation and Traffic Prediction based on DDPG and Federated Learning (DDPG 및 연합학습 기반 5G 네트워크 자원 할당과 트래픽 예측)

  • Seok-Woo Park;Oh-Sung Lee;In-Ho Ra
    • Smart Media Journal
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    • v.13 no.4
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    • pp.33-48
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    • 2024
  • With the advent of 5G, characterized by Enhanced Mobile Broadband (eMBB), Ultra-Reliable Low Latency Communications (URLLC), and Massive Machine Type Communications (mMTC), efficient network management and service provision are becoming increasingly critical. This paper proposes a novel approach to address key challenges of 5G networks, namely ultra-high speed, ultra-low latency, and ultra-reliability, while dynamically optimizing network slicing and resource allocation using machine learning (ML) and deep learning (DL) techniques. The proposed methodology utilizes prediction models for network traffic and resource allocation, and employs Federated Learning (FL) techniques to simultaneously optimize network bandwidth, latency, and enhance privacy and security. Specifically, this paper extensively covers the implementation methods of various algorithms and models such as Random Forest and LSTM, thereby presenting methodologies for the automation and intelligence of 5G network operations. Finally, the performance enhancement effects achievable by applying ML and DL to 5G networks are validated through performance evaluation and analysis, and solutions for network slicing and resource management optimization are proposed for various industrial applications.

Development of Algerian Weighted Mean Temperature Model for High Accurate Precipitable Water Vapor (고정확도 가강수량 획득을 위한 알제리 가중평균기온 모델 개발)

  • Sim, SeungHye;Song, DongSeob
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.33 no.1
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    • pp.53-62
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    • 2015
  • The water vapor including latent heat is the important component in an atmospheric circulation and in a monitoring of the Earth's climate changes, as well as in the weather forecast improvement. In this study, to establish the Algerian weighted mean temperature model, a linear regression method had been developed under 5 radiosonde observations for a total 24,694 profiles from 2004 to 2013. An weighted mean temperature is a key parameter in the processing of PWV from GNSS tropospheric delays. The result from the study has expected to provide an useful model to demonstrate the realization and utility of using the ground-based GNSS meteorology technique that will bring improvements in weather forecasting, climate monitoring in Algeria.

User Interface Experiment Model Design for Touch-Screen Based on Navigation System (터치스크린 기반 항해 시스템을 위한 사용자 인터페이스 실험 모델 설계)

  • Jeon, Hyun-Min;An, Jae-Yong;Oh, Seung-Yup;Park, Peom
    • KIPS Transactions on Software and Data Engineering
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    • v.3 no.11
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    • pp.503-510
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    • 2014
  • With the development of electronic communication technology, the ship's navigational equipment is being digitized, and it has being studied touch-screen-based navigation user interface. However, due to the influence of environmental factors such as waves, it has a potential problem hazardous marine accident occurs due to incorrect operation, the systematic research in consideration of this be done do not. In this paper, we provide a user interface experimental model to verify the stability that takes into account the external environment of the touch-screen input on. Further, we simulated to verify that the interface of the touch screen, the effect of applying the input delay time and the size of the button is obtained through the experimental model proposed. It will be able to greatly contribute to studies of the interface robust touch screen user errors that can be analyzed by the experimental model is proposed to improve the ship, the overall system stability.

Characteristics of the Simulated ENSO in CGCM (대기-해양 접합 모델에서 모사한 ENSO의 특징)

  • Moon, Byung-Kwon
    • Journal of the Korean earth science society
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    • v.28 no.3
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    • pp.343-356
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    • 2007
  • This paper explored the characteristics of the interannual sea surface temperature (SST) variability in the equatorial Pacific by analyzing the simulated data from a newly coupled general circulation model (CGCM). The CGCM simulates well the realistic ENSO variability as well as the mean climatologies including SST, seasonal cycle, precipitation, and subsurface structures. It is argued that the zonal gradient of SST in the equatorial Pacific is responsible for the over-energetic SST variability near the equatorial western boundary in the model. This variability could also be related to the strong westward propagation of SST anomalies which resulted from the enhanced the zonal advection feedback. The simple two-strip model supports this by sensitivity tests. Analysis of the relationship between zonal mean thermocline depth and NINO3 SST index suggested that the ENSO variability is controlled by the recharge-discharge oscillator of the model. The lead-lag regression result reveals that heat buildup process in the western equatorial Pacific associated with the increase of the barrier layer thickness (BLT) is a precedent condition for El $Ni\widetilde{n}o$ to develop.