• Title/Summary/Keyword: 주가정

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Case report : The Bisphosphonate-associated Osteonecrosis of the Jaw(BONJ) (증례 보고: 악골에 발생한 비스포스포네이트 관련 골괴사증 (BONJ))

  • Kim, Kyun-Yo;Ko, Yu-Jung;Hur, Yun-Kyung;Choi, Jae-Kap
    • Journal of Oral Medicine and Pain
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    • v.34 no.3
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    • pp.295-301
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    • 2009
  • Recently, bisphosphonate-associated osteonecrosis of the jaw(BONJ) is added to the list of diseases of the oromaxillofacial region. BONJ is defined as exposed bone in the jaw that does not heal within 8 weeks after identification, in a patient who has been received to bisphosphonates and has not taken radiation therapy to the craniofacial region. Bisphosphonates binded to bone mineral are concentrated in highly active remodeling site, reside in the skeleton for a long time, and do a role as powerful inhibitors of bone resorption. As the patients receiving bisphosphonates therapy grow in number, the patients of BONJ would go on increasing in Korea. We would like to present two patients who were suspected to BONJ, describe the outline of BONJ, and mention importance of our understanding about BONJ. BONJ is rare disease, but once it develops, its prognosis is very poor. Our adequate understanding of BONJ is necessary to prevent it and cope with it properly.

Characterization and Outbreak Pattern of Isolated Influenzavirus in Busan, 2000-2002 Years. (최근 3년 부산지역에서 분리한 인플루엔자바이러스의 특성 및 발생 양상)

  • 정명주;조경순
    • Microbiology and Biotechnology Letters
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    • v.31 no.4
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    • pp.329-333
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    • 2003
  • Influenzavirus were isolated from patients with acute respiratory infections in Busan during 2000-2002 and characterized their antigenic properties. In 2000, 39 viruses were isolated and they were identified as Influenzavirus. Among the isolated influenzavirus, 23 were A type influenzavirus and 16 were B type influenzavirus. As a result of antigenic characterization, the influenzavirus were determined to A/Sydney/05/97 (H3N2)-like, A/Beijing/262/95 (H1N1)-like, and B/Harbin/07/94-like virus. In 2001, 56 viruses were isolated and all of the viruses were identified as influenzavirus. They were A/Panama/2007/99 (H3N2)-like and A/Newcaledonia/20/99 (H1N1)-like virus In 2002, 114 Influenzaviruses were isolated. Among the isolated influenzavirus, 83 were A type influenzaviruses, and 31 were B type influenzaviruses. They were A/Panama/2007/99 (H3N2)-like, A/Newcaledonia/20/99 (H1N1)-like and B/Beijing/243/97, B/Honkong/22/2001, B/Sichuam/379/99-like virus when determined their antigenic properties. These results may be useful for the establishment of reliable epidemic data.

Comprehensive Evaluation of Freeway Surface Conditions based on User's Satisfaction (이용자 만족도를 고려한 고속도로 노면상태 종합평가에 관한 연구)

  • Son, Young-Tae;Lee, Jin-Kak;Lee, Shin-Ra;Jung, Chul-Gie
    • International Journal of Highway Engineering
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    • v.12 no.3
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    • pp.37-47
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    • 2010
  • This research is aimed at comprehensively evaluating the condition of a road surface of a highway in satisfaction of its users. This research conducted an overall evaluation of a road surface condition by adding qualitative data, or a driver's satisfaction to the existing quantitative elements, whereas the existing research put its focus on a correlation analysis with quantitative factors and qualitative factors through a statistical method. As for an evaluation method, this research conducted an overall evaluation by using Grey System Theory which makes possible an integrated evaluation. The analyzed results make it possible to diagnose the current conditions of each section of object roads and to predict the potentially changeable conditions for the time to come. In addition, these analyzed results could hopefully be applied to the maintenance of freeways through diverse methods. It is hoped that the evaluation of a road surface condition of a highway in satisfaction of its user could be helpful to keeping up the satisfaction of a driver and passenger on the highway by more than a certain level. In addition, the analyzed data on the influence of data value observed by comprehensively evaluating a variety of elements could be used as a secondary means of the decision-making process in relation to road maintenance. On top of that, it could be used as a means of improving road maintenance system and offering the improved driving environment of the highway.

Immunoblot analysis for serum antibodies to Pneumocystis carinii by age and intensity of infection in rats (흰쥐의 연령과 감염과정에 따른 폐포자충에 대한 항체형성 양상)

  • 홍성태;이미정
    • Parasites, Hosts and Diseases
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    • v.33 no.3
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    • pp.187-194
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    • 1995
  • The present study aims to observe changing patterns of serum antibody to hleumuvstis calinii in normal rats of different ages and in immunosuppressed rats. The serum IgG antibody was observed by immunoblotting with crude antigen of f carinii which were purified from the lungs of infected rats. The crude antigens separated in SDS-PAGE resolved more than 20 protein bands from 20 to 200 kDa. Of them,40-45, 50-55, 116 and 200 kDa bands were major antigens of R cori.nii. Most of the normal rats of up to 4 weeks had the antibodies reacting the 4 bands, but none of 8-week-old rats revealed the specific antibody. After the rats grew for 40 weeks, all were found to have the antibody in their serum. Same pattern of serum antibody level by age was found in ELISA. When immunosuppressed rats became heavily infected, the antibody in their serum decreased distinctively. The present results suggest that antibodies in normal newborn rats are transferred from their mother and lowered up to 8 weeks. Thereafter, the levels of the antibodies begin to increase by natural exposure to R cnrinii. It was also confirmed that the intensity of P cnrinii infection is inversely related with levels of serum antibodies.

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Relation of cyst counts with numbers of total nuclei of Pneumocystis carinii in rats (흰쥐 주폐포자충에 있어서 도말표본상 포낭의 수와 핵의 총 수와의 상관성)

  • Hong, Seong-Tae;Yu, Ji-Suk;Lee, Mi-Jeong
    • Parasites, Hosts and Diseases
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    • v.32 no.3
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    • pp.171-176
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    • 1994
  • Wistar rats were induced of Pneumowstis cayinii infection by injection with methyl-prednisolone to correlate the cyst counts and numbers of nuclei. Seven sections of the lungs were examined by impression smears and also whole lung homogenates were screened for nucleus counting for each rat. At the first week of the experiment, all of the Impression smears except one were cyst negative but trophic forms were counted around 106. At the third week, the cysts appeared one per 20 Immersion oil lens fields. The nuclei were on the order of 107 at this period, and this amount of Pc is regarded as the limit of cyst detection on Impression smears. When the nuclei were over 109 in the lungs, the cysts were counted about 50 in 20 microscopic fields. The organisms were distributed in the lungs without any predilection focus. The present data suggest that the trophic forms, proliferate first and the cysts appear later in the lungs.

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Physicochemical Quality Change of Enzyme-Treated Centella asiatica and Preparation of Jam using Enzyme-Treated Centella asiatica (효소처리 병풀(Centella asiatica)의 이화학적 품질 변화 및 이를 이용한 잼의 제조)

  • Lee, Kyung-Haeng;Joo, Ga-Young;Kim, Chae-Young;Han, Ki-Jung;Jang, Da-Bin;Yun, Ji-Hye;Yu, Kwang-Won;Bae, Yun-Jung
    • The Korean Journal of Food And Nutrition
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    • v.34 no.6
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    • pp.612-620
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    • 2021
  • To increase the utilization of Centella asiatica (CA), enzymes such as cellulase and pectinase were added and the physicochemical properties of the treated CA were analyzed. In addition, apple-CA jam was prepared using the enzyme-treated CA, which had the best antioxidant properties, and the physicochemical and sensory qualities of the jam were measured. There was a high content of ascorbic acid, polyphenols, flavonoids, reducing sugar, amino acid, minerals and DPPH radical scavenging activity in the enzyme-treated group. The antioxidant component and activity in the jam prepared by adding enzyme-treated CA increased with an increase in the amount of enzyme-treated CA. In the soluble solids, the higher the amount of enzyme-treated CA, the higher the value, but there was no significant difference in pH. The sensory evaluation of the jam, in particular the taste, showed that the highest preference was observed when the enzyme-treated CA was added in the range of 5.0~6.7%, and the control group showed the lowest preference. There was no significant difference in flavor and spreadability among the treatment groups, however, the control group showed the highest color preference. In the overall acceptability, when 5.0% of enzyme-treated CA was added, the highest acceptability was shown.

A study on the effect of tax evasion controversy on corporate values in internet news portals through big data analysis (빅데이터 분석을 통한 인터넷 뉴스 포털에서의 탈세 논란이 기업 가치에 미치는 영향 연구)

  • Lee, Sang-Min;Park, Myung-Ho;Kim, Byung-Jun;Park, Dae-Keun
    • Journal of Internet Computing and Services
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    • v.22 no.6
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    • pp.51-57
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    • 2021
  • If a company's actions to save or avoid taxes are judged to be tax evasion rather than legal tax action by the tax authorities, the company will not only pay tax but also non-tax costs such as damage to corporate image and stock price decline due to a series of tax evasion-related news articles. Therefore, this study measures the frequency of occurrence of tax evasion controversial keywords in internet news portal as a factor to measure the severity of the case, and analyzes the effect of the frequency of occurrence on corporate value. In the Korean stock market, we crawl related articles from internet news portal by using keywords that are controversial for tax evasion targeting top companies based on market capitalization, and generate a time series of the frequency of occurrence of keywords about tax evasion by company and analyze the effect of frequency of appearance on book value versus market capitalization. Through panel regression and impulse response analysis, it is analyzed that the frequency of appearance has a negative effect on the market capitalization and the effect gradually decreases until 12 months. This study examines whether the tax evasion issue affects the corporate value of Korean companies and suggests that it is necessary to take these influences into account when entrepreneurs set up tax-planning schemes.

Effects of No-Tillage on Pepper Growing in the Greenhouse with Organic Soil (시설 고추 무경운 유기재배 효과)

  • Yang, Seung-Koo;Seo, Youn-Won;Kim, Hyun-Woo;Kim, Byeong-Ho;Kim, Yong-Sun;Im, Gyeong-Ho;Kim, Hong-Jae;Kim, Jeong-Geun
    • Proceedings of the Korean Society of Organic Agriculture Conference
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    • 2009.12a
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    • pp.287-287
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    • 2009
  • 우리나라의 시설재배면적은 51,237ha에 이르며 수경재배 면적을 제외하면 대부분 경운재배를 하고 있는 실정이다. 경운 작업은 대형 농기구를 이용하여 경운하기 때문에 시설내 토양 입자가 단립으로 잘게 부서지며 대형농기구로 인하여 토양이 답압되고 경운층 아래 경반층이 형성되어 뿌리 발육과 배수 불량의 원인을 제공하게 된다. 경운은 기존에 설치되어 있는 관수시설과 지주, 멀칭을 제거한 후 유기물을 투입하고 2~3회 경운작업 후 다시 소형농기구를 이용하여 이랑을 조성한다. 그리고 제거된 관수시설, 멀칭, 지주를 다시 설치하여야 하기 때문에 시설의 경운재배는 가장 고통스러운 악성노동을 수반하게 된다. 따라서 본 시험에서는 시설 고추 유기재배 시 무경운재배 효과에 대하여 검토하고자 전남 나주시 남평읍 평산리 "JD 중동통 미사질양토"에서 시험을 수행하였다. 2009년 3월 11일 "녹광" 고추 품종을 재식 거리 135${\times}$38cm로 정식하여 7월 27일까지 재배한 후, 시험포를 1/2로 나누어 트렉터를 이용하여 경운작업을 실시하고 2009년 8월 1일 억제작형으로 "녹광" 고추 품종을 정식하였다. 그리고 나머지 시험포 1/2은 전작물을 재배한 이랑에 경운작업을 생략하고 전작물 고추의 식물체는 지제부를 절단하여 분해되도록 고랑을 피복하였으며, 고추 포기와 포기 사이에 무경운으로 고추를 정식하여 시험을 수행하였다. 고추 정식 전 7월 30일에 경운 시험포에 10a당 29톤의 물을 관수하였으며, 무경운 시험포에는 10a당 48톤의 물을 관수하고, 관수 2일 후 시험포의 습도와 이랑에 발생되는 균열수를 조사하였다. 이랑의 수분함량은 표토 0.23%, 토양 30cm 깊이의 수분함량은 0.18%로 경운방법에 따라서 차이가 없었으나 토양 20cm 깊이의 수분함량은 경운은 0.25%, 무경운은 0.14%로 경운재배 토양에 비하여 뿌리의 주요 분포지역인 작토층의 수분함량이 44% 정도 낮았다. 그리고 경운재배 이랑에서는 7~35cm 정도 되는 균열이 m당 22개정도 발생되었으나 무경운에서는 관찰되지 않았다. 시설 토양의 생물다양성 지표가 되는 미소동물의 분포를 조사한(9월 16일) 결과 경운재배 토양에서는 보리톡톡기 등 8종 97개체가, 무경운 토양에서는 10종 101개체가 포획되었다. 경운 방법에 따른 시설 유기재배 고추의 수확과수는 주당 139~141과, 수량은 1,367~1,431g/주가 수확되고 10a당 수량은 경운재배가 2,790kg, 무경운재배는 2,666kg이 생산되어 경운방법에 따른 수량 차는 인정되지 않았다. 경운방법에 따른 경영비를 분석한 결과 무경운은 경운재배에 비하여 10a당 유기질 비료비 178천원, 대농구상각비 211천원, 노력비 261천원의 절감으로 경운재배 경영비 4,815천원/10a 대비 약 14%의 경영비가 절감되었다. 그리고 작기마다 반복되는 경운작업과 관수시설, 멀칭, 지주설치 작업을 1회 설치 작업으로 연속사용이 가능하여 시설재배에서 가장 고통스러운 악성노동의 회피가 가능하였다.

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Effects of Fatty Acids and Vitamin E Supplementation on Antioxidant Systems in the Liver and Serum of the Second Generation Rat (지방산 및 비타민 E 보충 식이가 제2세대 흰쥐 간조직과 혈청의 항산화체계에 미치는 영향)

  • 황혜진;박정화;엄영숙;정은정;김수연;이양자
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.31 no.2
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    • pp.257-262
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    • 2002
  • Effects of dietary fatty acids and vitamin E on antioxidant system were studied in rat liver and serum. Sources of dietary fat (10 wt%) were safflower oil (SO) poor in $\omega$3 fatty acid and mixed oil (MO) with computer-adjusted fatty acid ratios (AA/DHA=1.4, $\omega$6/$\omega$3=6.3, P/M/S=1.0/l.5/1) with (ME) and without (MO) vitamin E (500 mg/kg diet). Rats were fed the three kinds of diet from 3~4 wks prior to the conception. At the age of 3 and 9 wks of the second generation rat, antioxidant vitamins and glutathione peroxidase (GSH-Px), superoxide dismutase (SOD) activities were measured in the liver and serum. The concentrations of $\beta$-carotene were lower in ME than in MO and SO in the liver at the age of 3 wks. It seemed that vitamin E has an inhibitory action on the uptake of $\beta$-carotene or acts as a preferred antioxidant to $\beta$-carotene. The concentrations of lycopene were lower in SO than in MO in the liver at the age of 3 wks. The concentrations of cryptoxanthin showed no significant changes within groups. The activities of GSH-Px tended to increase in ME compared to MO and the ratios of SOD/GSH-Px tended to decrease in ME compared to MO in the liver at the age of 3 weeks. The activities of antioxidant enzyme at the age of 3 weeks and 9 weeks were similar. This suggested that the activity level of antioxidant enzymes reached to the adult level at the age of 3 weeks which is the end point of lactation period.

An Implementation of Dynamic Gesture Recognizer Based on WPS and Data Glove (WPS와 장갑 장치 기반의 동적 제스처 인식기의 구현)

  • Kim, Jung-Hyun;Roh, Yong-Wan;Hong, Kwang-Seok
    • The KIPS Transactions:PartB
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    • v.13B no.5 s.108
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    • pp.561-568
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    • 2006
  • WPS(Wearable Personal Station) for next generation PC can define as a core terminal of 'Ubiquitous Computing' that include information processing and network function and overcome spatial limitation in acquisition of new information. As a way to acquire significant dynamic gesture data of user from haptic devices, traditional gesture recognizer based on desktop-PC using wire communication module has several restrictions such as conditionality on space, complexity between transmission mediums(cable elements), limitation of motion and incommodiousness on use. Accordingly, in this paper, in order to overcome these problems, we implement hand gesture recognition system using fuzzy algorithm and neural network for Post PC(the embedded-ubiquitous environment using blue-tooth module and WPS). Also, we propose most efficient and reasonable hand gesture recognition interface for Post PC through evaluation and analysis of performance about each gesture recognition system. The proposed gesture recognition system consists of three modules: 1) gesture input module that processes motion of dynamic hand to input data 2) Relational Database Management System(hereafter, RDBMS) module to segment significant gestures from input data and 3) 2 each different recognition modulo: fuzzy max-min and neural network recognition module to recognize significant gesture of continuous / dynamic gestures. Experimental result shows the average recognition rate of 98.8% in fuzzy min-nin module and 96.7% in neural network recognition module about significantly dynamic gestures.