• Pediatric Infection and Vaccine
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• v.23 no.1
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• pp.67-71
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• 2016

Erythema nodosum (EN) is a painful skin disease characterized by erythematous tender nodules located predominantly over the extensor aspects of the legs. Various etiological factors, including infection, drug administration, and systemic illness have been implicated as causes of EN. Mycoplasma pneumoniae is one of rare infectious agents to cause EN in children. We report a case of a 7-year-old boy with context of respiratory illness and skin lesions with arthralgia. From stepwise approaches, IgM antibody against M. pneumoniae was positive with titers of 12.18, consistent with respiratory infection of M. pneumoniae and histopathology showed findings of septal and lobular inflammation without vasculitis consistent with EN. In addition, we reviewed the pathogenesis of this disease based on our case and the previous reports.

• Korean Journal of Veterinary Research
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• v.41 no.4
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• pp.579-582
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• 2001

Twenty one Spontaneously Hypertensive Rats(SHR) that were 4- to 21-month-old were examined histopathologically and serologically during a routine health monitoring of the rat colony. The results of the enzyme linked immunosorbent assay(ELISA) for murine pathogens demonstrated that 14 of 21 SHR rats had antibodies to Mycoplasma pulmonis. Histopathologically, the mycoplasma positive SHR rats were observed to have the typical pulmonary lesions which are characterized by the hyperplasia of the lymphoid tissue around the bronchi, bronchioles and vessels. Based on the histopathological findings and serological results, this case was diagnosed as a murine mycoplasmosis of SHR rats.

• Journal of Veterinary Clinics
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• v.31 no.2
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• pp.117-120
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• 2014

An 11-year-old intact female Maltese was referred because of 1 week history of cluster seizure episodes. Based on brain CT scan, brain tumor was strongly suspected. The patient was euthanized according to client's request and we performed necropsy after euthanasia. The gross findings of the postmortem coronal sections of the brain showed that the mass was relatively well-demarcated, reddish in colored, and was present inside the left lateral ventricle and compressed adjacent tissues. The tumor mass had 2 distinct histopathological features: perivascular pseudorosette-like structures and a whirl-like arrangement of fibrillary cells. The immunohistochemical profile showed strong GFAP positivity and moderate S-100 expression, sparsely dotted staining with Ki-67. Based on the histopathological and immunohistochemical findings, the present case diagnosed to ependymoma.

• Journal of Veterinary Clinics
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• v.30 no.4
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• pp.296-300
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• 2013

A 7-year-old castrated male Yorkshire Terrier was presented with a palpable intra-abdominal mass. In radiography, a large radioopaque renal mass and small abdominal mass were found on dorsal area of the abdomen. Grossly, red to brown color mass and a cystic structure (hydronephrosis) were embedded in the right kidney. Histopathologically, the mass had many irregular shaped neovascular channels lined by polygonal or oval shaped endothelial cells. These vessels and neoplastic cells had great invasive tendency to adjacent connective or fat tissues. Small abdominal mass had identical morphologic features as in renal mass. According to immunohistochemistry, the neoplastic cells in renal mass demonstrated strong positive signals for vimentin and CD31, and weak positive for von Willbrand factor. However, there were no positive reactions for cytokeratin. Based on the gross, histopathology and immunohistochemistry, this mass was diagnosed as primary renal hemangiosarcoma in a Yorkshire Terrier dog.

• Journal of Veterinary Clinics
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• v.23 no.2
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• pp.102-104
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• 2006

The purpose of this study was to document the histology of canine acupoints. Acupunctural needles were inserted by 0.5 to 1 cm depth into acupoints Nei-guan (Inner pass, PC06), Gan-shu (Liver Association Point, BL18), Shen-shu (Kidney Association Point, BL23) and Pangguang-shu (Bladder Association Point, BL28) in 4 dogs, and the tissues around the acupoints were examined. Light microscopy was used to observe the surrounding structures of each point. Nerve fibres, small vessels and muscle spindles were found around the tip of the needle in every case, although they occurred not so often at nonacupoint in nearby region or nonacupoint in the areas, such as skin, subcutaneous tissue and muscle. Therefore, it is suggested that nerve fibres, small vessels and muscle spindles may be potential acupoint receptors.

• Korean Journal of Veterinary Research
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• v.33 no.3
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• pp.465-469
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• 1993

This paper dealt with the histopathological findings on the natural cysticercosis in pigs. Three cases of porcine cysticercosis, which had been kept in the Department of Veterinary Medicine, Cheju. University more than ten years, were histopathologically examined in order to see the host reaction to the parasite. Capsules containing scolex were mainly found in the fascia of skeletal muscle, heart, and brains. Microscopically, cysticerci in the epicardium and the fascia of skeletal muscles were encapsulated with fibroblasts and collagen fibers. Around capsules, there was infiltration of eosinophils, lymphocytes and macrophages, although the degree and severity of inflammatory reaction varied case by case. Cerebral cortex also had the inflammatory exudate of lymphoid cells in the vicinity of the scolex. whereas perivascular lymphocytic cuffings were commonly seen around capsules. GFAP immunoreactive fibers formed a limiting membrane along the outer side of capsules. There was also proliferation of GFAP-positive astrocytes encirling infiltrating lymphocytes around vessels. In the central nervous system, astrocytes and lympoid cells play an important role in the demarcation of cysts and local immunity, respectively. In conclusion, host tissue reaction in porcine cysticercosis seemed to vary significantly according to the affected organs of pigs. It is assumed that capsules containing worms seemed to be formed at early stage of cysticercosis.

• Investigative Magnetic Resonance Imaging
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• v.3 no.2
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• pp.113-124
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• 1999

종래의 영상진단 방법은 골수의 이상을 검사하는데 상당한 제한점이 있는 상황에서 MR 영상은 골수를 칩습한 병변을 직접 묘출할 있는 우선적인 영상진단법으로 그 이용이 점차 증대되고 이다. 비록 골수 천자나 생검에 비해 조직학적 진단의 특이성은 떨어지나 환자의 임상증세와 혈액상을 연관지어 MR 영상 소견을 판독하면 골수의 병변을 진단하고 그 치료에 관한 반응을 해석하는데 유용한 정보를 줄 수 있으리라 기대된다.

• Korean Journal of Veterinary Pathology
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• v.6 no.2
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• pp.69-72
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• 2002

1. 본 질병에 대한 다른 이름; 모낭충증, demodecosis. 2.원인체; Demodex canis. 3. 병리기전; 모낭충의 감염-농포(papule)-결절(nodule)-탈모-2차 세균감염. 4. 임상증상; 탈모, 소양증. 5. 병리조직 소견; 모낭의 확대, 표피세포의 각화항진, 모낭주위, 모낭내, 혈관 주위에 림프구 침윤, 소수의 대식구, 호산구침윤. 6. 진단; Scratching, 병리조직학적 검사. 7. 감별진단; 진균감염. 8. 치료 및 예방대책; Ivermectin. (중략)

• Journal of the korean academy of Pediatric Dentistry
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• v.29 no.3
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• pp.463-468
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• 2002

The unicystic ameloblastoma deserves separate consideration on the basis of its clinical, radiologic, and pathologic features and its response to treatment. It refers to those cystic lesions that show clinical, radiographic, or gross features of a jaw cyst, but on histologic examination show a typical ameloblastomatous epithelium lining part of the cyst cavity. The lesion is most commonly found on the mandible posterior area, and often asymptomatic, although large lesions may cause a painless swelling of the jaws. The lesion typically appears as a circumscribed radiolucency that surrounds the crown of an unerupted molar. These are usually considered to be a dentigerous, residual cyst on the relationship of the lesion to teeth in the area. Three histopathologic variants of unicystic ameloblastoma may be seen. 1) Luminal type, 2) Intraluminal type, 3) Mural type. In this case, these tumor was treated as cysts by enucleation with iliac bone graft, and the diagnosis of ameloblastoma is made after microscopic examination of the presumed cyst.

• The Journal of the Korea Contents Association
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• v.10 no.5
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• pp.259-266
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• 2010

Clostridium difficile-associated disease (CDAD) is an important nosocomial infectious diarrhea and is associated with antibiotic use. Recently, incidence of C. difficile has been increasing in hospitals. A total of 1,329 stool specimens were examined from January, 2005 to December, 2008. This study analyzed the incidence and clinical characteristics of C. difficile infections on them. Out of 1,329 stool specimens, 283 specimens showed toxin A/B positive, using EIA. The positive rate was 21.2%; with the highest incidence among and above the 70years old. On endoscopy, psedo membranous colitis was found in 57.7%, and 19.5% of patients were normal. Pathologic finding showed PMC in 26.8% of patients, AAC in 52.2%. C. difficile was associated with PMC, however, endoscopic and pathologic findings tests showed normal to PMC.