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http://dx.doi.org/10.5392/JKCA.2010.10.5.259

Analysis of Clostridium Difficile Toxin Value in Diarrhea Patients  

Kwon, Se-Young (대구보건대학 임상병리과)
Yoon, In-Sook (대구보건대학 임상병리과)
Publication Information
The Journal of the Korea Contents Association / v.10, no.5, 2010 , pp. 259-266 More about this Journal
Abstract
Clostridium difficile-associated disease (CDAD) is an important nosocomial infectious diarrhea and is associated with antibiotic use. Recently, incidence of C. difficile has been increasing in hospitals. A total of 1,329 stool specimens were examined from January, 2005 to December, 2008. This study analyzed the incidence and clinical characteristics of C. difficile infections on them. Out of 1,329 stool specimens, 283 specimens showed toxin A/B positive, using EIA. The positive rate was 21.2%; with the highest incidence among and above the 70years old. On endoscopy, psedo membranous colitis was found in 57.7%, and 19.5% of patients were normal. Pathologic finding showed PMC in 26.8% of patients, AAC in 52.2%. C. difficile was associated with PMC, however, endoscopic and pathologic findings tests showed normal to PMC.
Keywords
Clostridium Difficile; Pseudomembranous Colitis(PMC); Clostridium Difficile Toxin Value;
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