• Journal of Hospice and Palliative Care
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• v.8 no.2
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• pp.190-199
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• 2005

Purpose: Objectives of this study was to investigate the level of anxiety and depression according to the stages of autologous and allogeneic hematopoietic stem cell transplantation (HSCT). It would be provide the basis for effective psycho-emotional nursing intervention. Methods: We report on 52 patients, including 19 with autologous HSCT, and 33 with allogeneic HSCT from August 2002 to August 2003, at a university hospital. Spielberger's State-Trait Anxiety Inventory and Jung's Depression Inventory were used to measure levels of anxiety and depression, respectively, at admission time, the day before HSCT, and discharge time. Data was analyzed using SAS program that included Chi-square test, Fisher's exact test, repeated measures ANOVA and Stepwise multiple regression analysis. Results: In all stages of HSCT, the level of anxiety of patients who underwent allogeneic HSCT was significantly higher than that of autologous HSCT (P=0.047). The depression at the day before HSCT was significantly higher than that at admission. The major variable affecting anxiety in autologous HSCT was depression. Specially depression and gender were significant predictors to explain anxiety in allogeneic HSCT at admission time (61%). Experience of relapse and gender were significant predictors to explain anxiety in allogeneic HSCT at discharge time (36%). Conclusion: We recommend that the anxiety and depression be researched during the stages of allogeneic HSCT, specifically in the day before HSCT. It is necessary to develop an effective psycho-emotional nursing intervention according to the stages of HSCT.

• Restorative Dentistry and Endodontics
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• v.34 no.2
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• pp.113-119
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• 2009

The purpose of this study was to compare the tensile bond strength of several self-adhesive resin cements bonded to dentin surfaces with different wet conditions. Three self-adhesive resin cements: Rely-X Unicem (3M ESPE, St. Paul, MN. USA). Embrace Wetbond (Pulpdent. Oakland. MA. USA). Maxcem (Kerr. Orange. CA. USA) were used. Extracted sixty human molars were used. Each self-adhesive resin cement was adhered to the dentin specimens (two rectangular sticks from each molar) in different wet conditions. Tensile bond strength were measured using universal testing machine (EZ Test. Shimadzu corporation. Kyoto. Japan) at a crosshead speed of 1.0mm/min. After the testing. bonding failures of specimens were observed by Operative microscope (OPMI pro, Carl Zeiss. Oberkochen, Germany). T-test was used to evaluate the effect of dentin surface wetness. One-way ANOVA test was used to evaluate the tensile bond strength of self-adhesive resin cements in the same condition. Scheffe's test was used for statistical analyzing at the 95% level of confidence. The result showed that wetness of dentin surface didn't affect tensile bond strength of self-adhesive resin cements and Maxcem showed the lowest tensile bond strength.

• The Korean Journal of Mycology
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• v.12 no.4
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• pp.141-152
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• 1984

Aspergillus niger van Tieghem was cultured by the method of synchronous and submerged culture. Throughout the culture, sporulation was occured. Highly phosphorylated nucleotides in sporulating mycelia were detected to assure whether the eucaryotic Aspergillus niger produce these substances or not during the differentiation. Phosphorylated nucleotides were extracted from the conidiophore, bearing mycelia and spore forming body, these nucleotides were identified by TLC with P.E.I. cellulose. Guanosine tetraphosphate was found in both phialide forming mycelia and spore forming body. The contents of free amino acids were assayed and its level was found to increase at early stage of sporulation. The effects of 8-azaguanine examined, it was found to prevent spore formation and to made abnormal structure. The effects of inosinic monophosphate and guanosine monophosphate on spore formation were examined, spore formation was enhanced by these nucleotides.

• Proceedings of the KSAR Conference
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• 2001.03a
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• pp.14-14
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• 2001

본 연구는 생명공학 관련 기술개발에 의하여 신소재 물질을 생산하고 사람에게 안전하고 생리활성이 높은 고가의 의료용 단백질 생산기술을 체계화하며 형질전환 가축을 이용한 유용물질 생산에 따른 산업화와 부가가치의 극대화에 그 목적이 있다. 유즙으로 사람의 빈혈치료제인 EPO(Erythropoietin)를 분비할 수 있는 형질전환돼지를 생산하기 위하여 WAP(Whey Acidic Protein) Promoter(2.6kb) 하류에 사람의 조혈촉진유전자(EPO: 2.6kb)를 연결시켜 미세주입용 재조합 벡터(WAP-EPO : 약 7.8kb)를 구축하였다. 구축된 재조합 벡터를 1세포기 수정란에 약 2ng/ul 농도로 미세주입한 다음 외과적 방법으로 이식하였다. 이식 후 분만 모돈으로부터 생산된 자돈의 꼬리조직을 이용 게놈DNA를 추출하고 PCR 검정을 한 결과, 유즙으로 사람의 빈혈치료제를 생산할 수 있는 유전자가 도입된 형질전환돼지 $\boxDr$새롬이$\boxUl$ (♂)를 확인하였다. 또한 이렇게 꼬리조직으로부터 확인된 새롬이의 혈액과 정액을 채취, 게놈 DNA를 추출하여 외래 유전자 삽입여부를 PCR 방법으로 검정한 결과 꼬리조직과 마찬가지로 혈액 및 정액에서도 외래유전자가 삽입되었음을 확인할 수 있었다. 이렇게 생산된 형질전환돼지 $\boxDr$새롬이$\boxUl$를 이용 계대번식을 통한 F$_1$ 산자의 생산과 유전자 전이율을 확인하기 위하여 $\boxDr$새롬이$\boxUl$정액을 이용한 인공수정을 실시하였다. 인공수정은 1999년 7월 1일부터 2000년 9월 8일 까지 총 78두의 모돈을 이용하였으며, 그 중 21두의 모돈이 분만하여 인공수정에 의한 분만율은 26.92%로 나타났다.(Table Omitted) Table 1에서와 같이 새롬이 정액을 이용한 인공수정에 의해 형질전환된 F$_1$ 자돈의 형질전환율은 17.98%로 나타났으며, 32두의 형질전환자돈 중 8두(암:4두, 수:4두)는 분만과 동시에 폐사하였거나 사육중 폐사하여 현재 24두(암:12두, 수:12두)가 생존하여 F$_1$ 간 교배계획에 의해 사육되고 있다. 이 중 암컷 4두는 현재 F$_2$ 자돈 생산과 함께 유즙내로 사람 빈혈치료제의 분비 유무를 검정중에 있으며, FISH 법에 의한 외래 유전자 삽입 검정을 확인 중에 있다.

• Journal of dental hygiene science
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• v.8 no.4
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• pp.323-329
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• 2008

The purpose of this study was to compare the oral health education effect and the satisfaction about the method between SDL and CCI on elementary school students. Method: The subjects of this study were 233 elementary school students in fourth grade (male: 56%, female: 44%) who attended two different elementary schools in Wonju Gangwon-do. They are divided into two groups and instructed by different method of the oral health education, SDL (Self-Directed Learning) and CCI (Conventional Classroom Instruction). The survey was conducted three times, preeducation, just after the education and one week after education. Collected data were analyzed into Chi-square test, Independent t-test and Repeated measure ANOVA using SPSS 12.0 K program. Result: 1. Changes of oral health knowledge: After the education, the average score of the oral health knowledge went up significantly in both groups. 2. Changes of oral health behavior: After the education, the average score of the oral health behavior rose up significantly in both groups and especially just after education, SDL group was recorded higher average score than CCI group. 3. Satisfaction: In both groups, the satisfaction rates about the education method were high (SDL: 88.9%, CCI: 99.1%). The main reason of satisfaction in SDL group was that the students were interested in the method of the education and the main reason of dissatisfaction was that they could not ask a question to the educator.

• Restorative Dentistry and Endodontics
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• v.36 no.2
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• pp.132-138
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• 2011

Objectives: The purpose of this study was to evaluate curing degree of three dual-cure resin cements with the elapsed time in self-cure and dual-cure mode by means of the repeated measure of micro-hardness. Materials and Methods: Two dual-cure self-adhesive resin cements studied were Maxcem Elite (Kerr), Rely-X Unicem (3M ESPE) and one conventional dual-cure resin cement was Rely-X ARC resin cement (3M ESPE). Twenty specimens for each cements were made in Teflon mould and divided equally by self-cure and dual-cure mode and left in dark, $36^{\circ}C$, 100% relative humidity conditional-micro-hardness was measured at 10 min, 30 min, 1 hr, 3 hr, 6 hr, 12 hr and 24 hr after baseline. The results of micro-hardness value were statistically analyzed using independent samples t-test and one-way ANOVA with multiple comparisons using Scheffe's test. Results: The micro-hardness values were increased with time in every test groups. Dual-cure mode obtained higher micro-hardness value than self-cure mode except after one hour of Maxcem. Self-cured Rely-X Unicem showed lowest value and dual-cured Rely-X Unicem showed highest value in every measuring time. Conclusions: Sufficient light curing to dual-cure resin cements should provided for achieve maximum curing.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.1
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• pp.111-120
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• 2019

This study is a quasi experimental study to investigate the effects of stroke prevention education program of Oriental Nursing on self-health perception, health behavior change, self-care and physiological index of adults over 55 years old and elderly people. The data were collected from August 12 to November 29, 2017. The 53 study subjects comprised 26 experimental subjects who agreed to participate in the education program and 27 control subjects. In the results, there was no statistically significant difference between the experimental group and the control group in general characteristics and research variables before the program; further, the two groups were homogenous. In the hypothesis test, the change in self-health perceptions of the experimental and control groups was t = -5.28 (p <.001), health behavior change was t = -4.24 (p <.001), self-care was t = -5.28 (p <.05), systolic blood pressure was t = 2.48 (p <.05), diastolic blood pressure was t = 2.78 (p <.05), and cholesterol was t = -3.94 (p <.001). There were statistically significant differences between the two groups and all four hypotheses were supported, which demonstrated the effectiveness of the program. These study results suggest that it is an effective program to change the self-perception of health and health behavior, improve self-care ability, and control the physiological index. It is expected that these findings will be useful in developing a future effective oriental nursing intervention. The education program should be continuously carried out, and the area needs to be expanded.

• Physical Therapy Korea
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• v.10 no.4
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• pp.23-31
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• 2003

본 연구는 상지운동 동안에 복부에 적용된 압력이 요부와 복부의 근피로도에 미치는 영향을 알아보았다. 연구대상자는 성인 남자 5명이었다. 연구대상자가 10 repetitions maximun (RM) 무게의 아령을 이용하여 1분 동안 상지운동을 수행 시 0 mmHg, 저압(30 mmHg), 중압(70 mmHg), 고압(100 mmHg)의 외부 압력이 복부에 적용되었고, 복직근, 외복사근, 내복사근, 척추기립근에서 근전도 자료가 수집되었다. 주파수 분석을 통하여 적용된 압력에 따라 각각의 근육에서 초기 10초 구간과 말기 10초 구간의 중앙주파수로 피로지수를 측정하였다. 통계학적 분석방법은 반복측정된 이요인 분산분석 ($4{\times}4$)과 사후검정을 이용하였다. 그 결과 압력의 차이에 의한 주효과가 나타났으며, 사후검정결과 0 mmHg 압력에 비해 30 mmHg, 100 mmHg에서 각각 피로지수가 유의하게 낮았다(p=.04, p=.015). 본 연구의 결과를 통하여 복부에 적용된 압력 (30 mmHg, 100 mmHg)이 근육의 피로도를 감소시킬 수 있음이 나타났다. 요부벨트를 이용하여 작업을 수행할 때, 고유수용성 감각 입력을 증가시키고 재손상을 방지하는 목적이외에도 근피로도를 감소시킬 수 있다는 가능성을 알 수 있었다.

• The Transactions of the Korea Information Processing Society
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• v.6 no.8
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• pp.2106-2112
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• 1999

In decision-making, information is the thing manufactured as the useful type for decision -making. We can improve the efficiency of decision-making by elimination of unnecessary information. Rough set is the theory that can classify and reduce the unnecessary. But the reduction process of rough set becomes more complex according to the number of attribute and tuple. After eliminating of the dispensable attributes using $\chi$2 and rough set, the indispensable attributes are used for the units of input layers in neural network. This rough-neural network can support more correct decision-making of neural network.

• Journal of Korea Port Economic Association
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• v.38 no.1
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• pp.49-71
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• 2022

The purpose of this paper is to study the effect of the corporate social responsibility by port operation organization on the brand asset, reputation and relationship performance perceived by interested parties. To achieve such a purpose, literature survey on various research papers and thesis, research report is carried out and also reliability analysis, validity test and multiple regression analysis using SPSS 18.0 are used. To verify a established research model for empirical analysis and hypotheses, questionnaires are distributed to the port operation organization, terminal operators, shipping companies and NGO. Total 414 copies of questionnaires were collected and used in this analysis. The main results of the study are summarized as below. First, it was confirmed that social responsibility of the port operation organization are classified into three categories; economic, legal, and charitable and ethical responsibility. Second, economic responsibility has a positive impact on the brand awareness and reputation. Third, legal responsibility has a positive impact on the trust and commitment. Fourth, charitable and ethical responsibility has a positive impact on brand image and awareness, reputation, trust and commitment. Further additional empirical research can be extended by distributing more questionnaires including several port operation organizations in Busan and Incheon.