• 한국수산과학회지
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• 제53권4호
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• pp.530-537
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• 2020

This study compared the survival rates, growth, and fatty acid content of larval Pacific cod Gadus macrocephalus fed with rotifers raised on different enrichment diets. We used four commercial rotifer enrichment products (one domestic, ER1, and three imported, ER2, ER3 and ER4). Twelve 200-L tanks were used, with three replicates per treatment. Larvae were fed rotifers 3 times daily at a rate of 5 rotifers/ml/feeding from 7 to 21 days post-hatch. At the end of the feeding trial, the survival rate and total length of larvae fed ER3 were greater than those of larvae fed ER1, ER2, or ER4. ER3 had the highest proportions of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and polyunsaturated acid (PUFA). Partially reflecting this composition, larvae fed ER3 had the highest proportions of DHA and PUFA. These results show a positive effect of rotifer DHA and PUFA proportions on the survival and growth rates of Pacific cod larvae.

• 한국콘텐츠학회논문지
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• 제16권4호
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• pp.301-312
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• 2016

본 연구는 호텔기업에서 고객들이 경험하는 소비특성이 재방문의도와 전환의도에 어떤 영향을 미치는지 살펴보고, 또한 고객들의 방문횟수에 따라서 재방문의도와 전환의도에 미치는 영향력이 조절되는지 검증하여 마케팅 전략 측면에 실무적 시사점을 제공하고자한다. 이를 위해서 국내 특1, 2급 호텔을 이용한 고객 534명을 대상으로 실증분석 하였고, 그 결과는 다음과 같다. 첫째, 호텔의 경험적 소비특성 중에서 유희성, 상징성, 유익성, 심미성이 재방문의도에 정(+)의 영향을 미치는 것으로 나타났다. 둘째, 호텔의 경험적 소비특성 중에서 상징성, 유익성, 심미성만이 전환의도에 부(-)의 영향을 미치는 것으로 나타났다. 더불어 재방문의도와 전환의도에 가장 큰 영향을 미치는 경험적 소비특성은 상징성임을 알 수 있었다. 셋째, 호텔의 경험적 소비특성 중 유희성, 공유성과 재방문의도의 영향관계는 방문횟수에 따라 조절되며, 호텔의 경험적 소비특성 중 유희성, 상징성과 전환의도와의 관계역시 방문횟수에 따라 조절되는 결과를 보였다. 이런 결과를 바탕으로 호텔기업에서는 효율적인 마케팅 전략을 수립할 수 있을 것이다.

• 한국수학교육학회지시리즈E:수학교육논문집
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• 제30권4호
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• pp.435-452
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• 2016

본 연구는 기하학습에서 공학도구를 활용하였을 때 도구화가 어떻게 이루어지는지와 이 도구화가 교수법과는 어떤 관계인지를 살펴보고자 하였다. 이를 위하여 중학교 학생 두 명을 대상으로 공학환경에서의 van Hiele 교수학습 모델에 근거한 4차시 학습지도안이 구성되었고 2015년 5월 관찰과 면담을 통해 자료수집이 이루어졌다. 학생들의 도구화는 준비기, 적응기, 응용기의 과정을 거치는 것으로 파악되었는데 학습차시를 진행하면서 시각화에 의존하는 준비기와 적응기에는 실제 시행착오적 과정이 활발히 일어남을 알 수 있었다. 하지만 시각화가 덜 필요한 단계, 즉 응용기에서는 도구의 역할이 자신의 추측과 정당화를 확인하는 것으로 바뀌는 것을 알 수 있다. 따라서 교사는 학생들의 이해수준에 맞추어 도구화 과정에 따른 교수법을 구성하여야 하며, 공학 도구사용이 학생의 학습을 자기주도적 학습으로 변화되도록 도와야 한다. 교사는 교수법에서 학생들의 도구화 과정에 대해 전체적인 구조를 파악할 수 있는 심도있는 고찰이 요구된다.

• 한국식생활문화학회지
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• 제29권6호
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• pp.659-667
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• 2014

Fruits are good sources of vitamins, minerals, fiber, and phytochemicals, which are known to reduce serum lipids, oxidative damage, and blood pressure as well as improve blood glucose control. The purpose of this study was to estimate nutrient quality indices of fruits by carrying out a critical analysis of pre-existing methods according to their nutritional compositions. Four methods were used to assess the nutrient indices of 26 fruits, which are frequently consumed by Koreans based on the fourth Korean National Health and Nutrition Examination Survey (2009). Naturally nutrient rich score (NNR), nutrient rich food (NRF), nutrient adequacy score (NAS), and nutrient density score (NDS) were used to calculate nutrient quality indices. The Korean Nutrition Society Food Composition database of fruits based on 100 g edible portions was used. The algorithm of each method included the mean percentage of daily values (Dietary Reference Intakes for Koreans, 2010) for particular nutrients based on consumption of 1,900 kcal/day. The relative score indicated that strawberries, kumquat, and lemon had high nutrient quality indices. In addition, mango, lemon, persimmon, strawberry, apricot, and tangerine fruits are rich in antioxidant nutrients such as ${\beta}$-carotene, vitamin C, vitamin E, and selenium. However, scores of nutrient quality indices did not imply that higher scores of particular fruits are superior. We suggest moderate seasonable consumption a variety of fruits. Our results can be used as a reference for consumers when they choose fruits.

• 한국식생활문화학회지
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• 제32권5호
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• pp.453-464
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• 2017

Vegetable soup has been reported to have anti-inflammatory, anti-oxidative and anti-cancer effects. In this study, five kinds of vegetable soup were developed using a new manufacturing process and compositional changes in raw material, and anti-cancer and immuno-stimulatory activities were evaluated. Cytotoxicity tests based on MTT assay revealed that all vegetable soups had strong inhibitory effects against CT26 mouse colon cancer cells, with soups including Solomon's seal being most effective based on comparison of $IC_{50}$ values. Apoptosis in response to vegetable soup was occurred by 3-5 fold on cancer cells compared to normal cells. Mouse splenocytes increased by 266-541% in response to addition of vegetable soup in an in vitro proliferation experiment. In co-culture with splenocytes and CT26 cancer cells, splenocytes increased by more than 280% in every vegetable soup treatment, while cancer cells decreased by about 60% and cytokines such as $IFN- {\gamma}$ and IL-12 were secreted from splenocytes in high levels only in response to vegetable soup including Solomon's seal. In conclusion, all vegetable soups developed in this study had anti-cancer effects, and vegetable soup including Solomon's seal showed the strongest anti-cancer and immuno-stimulatory effects. These results suggest that functionality of vegetable soup could be increased by changes in manufacturing processes and raw materials composition.

• 한국식생활문화학회지
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• 제28권5호
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• pp.438-449
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• 2013

During the Joseon Dynasty, medicinal foods derived from herbs were often more effective than traditional medicines. In addition, the royal family of the Joseon Dynasty believed that foods could be used as various disease treatments. Grain-based foods, especially medicinal porridges (藥粥), were most frequently used for diet therapy. We investigated various types of diet-related diseases suffered by King Injo (仁祖) as well as how the diseases were treated using medicinal porridges based on information in the SeungjeongwonIlgi (承政院日記), which is the daily record of the Royal Secretariat of the Joseon Dynasty. This study examined the SeungjeongwonIlgi of King Injo from his1st year (1623) to 27th year (1649) on a website database maintained by the National Institute of Korean History. According to the records, King Injo suffered from severe diarrhea several times due mainly to febrile disease (煩熱症) as well as abdominal dropsy (脹滿) throughout his entire life. Major diseases affecting King Injo were due to his unhealthy eating habits and psychological factors. For treatment, royal doctors prescribed around 15 medicinal porridges, including nelumbo (seed) porridge (Yeonja-juk), milk porridge (Tarak-juk), Chinese dioscorea porridge (Sanyak-juk), mungbean porridge (Nokdu-juk), perilla seed porridge (Imja-juk), adzuki-bean porridge (Pat-juk), soybean porridge (Kong-juk), Korean-leek porridge (Buchu-juk), and so on, in addition to other medical treatments. Diet therapy using medicinal porridges has been used throughout history since the Joseon Dynasty period. However, knowledge of traditional diet therapy and medicinal porridges used by monarchs in the Joseon Dynasty is insufficient. Therefore, in-depth study is needed to understand the theory of traditional medicinal foods as well as explore their application to patients in the context of modern medicine.

• 한국식생활문화학회지
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• 제30권4호
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• pp.395-405
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• 2015

Insamsokmieum (人蔘粟米飮), which is a kind of water gruels made with millet, ginseng, glutinous rice, and some minor ingredients, was frequently used as a medicinal food for the royal family, and it appeared first at the 10th year of King Sukjong's reign. We investigated Insamsokmieum through a literature review and the "SeungjeongwonIlgi(承政院日記)" of King Sukjong (肅宗) from his 1st year (1674) to 46th year (1720). We analyzed the nutritional value and efficacy of Insamsokmieum. In Oriental medicine, Insamsokmieum is prescribed mainly to treat symptoms such as nausea, languidness, and exhaustion in King Sukjong and Queen Inhyun (仁顯王后). In nutritional terms, Insamsokmieum has higher nutrition density than that of rice porridges (白粥) and has relatively high vitamin and mineral contents. Some nutrients such as leucine and glutamic acid, which are contained in the millet, are also known to help alleviate these symptoms. Whereas there have been studies on the efficacy and types of diet during the Joseon Dynasty, studies regarding nutrition characteristics are lacking. This study will demonstrate the superiority of dietary treatments of the Joseon Dynasty and their potential for application to modern nutrition.

• 한국수산과학회지
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• 제47권6호
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• pp.853-859
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• 2014

The goal of this study was to evaluate the effects of cryoprotectants [dimethyl sulfoxide (DMSO), methanol, polyethylene glycol, and propylene glycol], cryoprotectant concentrations (10% and 20%), equilibration time (3, 10, and 30 min), cooling rate ($3^{\circ}$, $5^{\circ}$, $7^{\circ}$, and $10^{\circ}/min$), and straw size (0.25 and 0.5 mL) for sperm cryopreservation of tetraploid Pacific oysters. There was a significant difference among the four cryoprotectants, with 10% DMSO yielding the highest post-thaw survival and activity index of sperm. A significant relationship was observed between the cryoprotectant and its concentration. The sperm with equilibration times of 30 min yielded higher post-thaw survival and activity indices than those with 3 and 10 min equilibration times. The sperm cooled at a rate of $5^{\circ}/min$ yielded the highest post-thaw survival and activity index, and the results were significantly different from those observed for cooling at $7^{\circ}$ and $10^{\circ}/min$. Post-thaw survival and activity indices of sperm using a 0.25-mL straw were significantly higher than those using a 0.5-mL straw.

• 약학회지
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• 제55권2호
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• pp.81-90
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• 2011

Most antineoplastic agents are nonselective in their mechanism of action, affecting noncancerous as well as cancerous cells, and resulting in acute effects such as irritation of mucous membranes and chronic effects such as genotoxicity, teratogenicity, and carcinogenicity. Healthcare workers occupationally exposed to antineoplastic agents are at risk. The present study aimed to develop and apply methods to monitor occupational exposure to antineoplastic agents, using cyclophosphamide (CP) as the model compound. To monitor environmental and biological exposure, potentially contaminated surfaces were wiped and 24 hour urine samples were collected from workers. Liquid chromatography combined with tandem mass spectrometry was performed, with a limit of detection of 0.05 ng/ml. Measurable amounts of CP were detected on 92% of the sampled surfaces, with a geometric mean of 175.22 $ng/m^2$. Despite the environmental contamination of the model compound, CP was below the detection limit in all urine samples. If workplace contamination cannot be completely avoided, it is importance to reduce exposure to the lowest possible levels. To this aim, efforts to minimize occupational exposure along with biological and environmental monitoring are required. The standardized sampling techniques, and specific and sensitive analytical methods reported in this study may be helpful in assessing occupational exposure and devising strategies to reduce exposure.

• 정보교육학회논문지
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• 제22권1호
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• pp.141-149
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• 2018

초등 디지털교과서의 교육적 효과를 분석하기 위해 2014년에 초등학교 3~4학년을 패널로 선정하여 종단연구를 수행하였다. 2016년에 초등학교 5~6학년이 된 학생들을 대상으로 설문조사를 실시하여 인지적 영역, 정의적 영역, 사회적 영역, 심체적 영역, 학습 역량 등을 평가하여 그 효과를 검증하였다. 그 결과, 3년간 디지털교과서를 사용한 5학년 학생들이 2년간 사용한 6학년 학생들보다 교육적 효과가 모든 영역에서 높게 나타났다. 또한, 3년 동안 디지털교과서를 사용하면서 학생들의 심체적 영역을 제외한 모든 영역에서 교육적 효과가 향상된 것으로 분석되었다. 이러한 교육적 효과는 학생들의 성적이 높을수록, 디지털교과서를 더 많이 활용할수록, 교사의 스마트교육 역량이 높을수록 더 높게 나타났다.