• Title/Summary/Keyword: 임상군

Search Result 3,466, Processing Time 0.026 seconds

Research on the Bacillus-fermented Enzamin Administration on Human NK Cell Activity and Bone Density of Hamster: A Pilot Study (Bacillus 발효액 Enzamin의 투여가 인체의 NK세포 활성도와 Hamster의 골밀도에 미치는 탐색연구)

  • Won, Ryu Seo;Fujii, Tokio;Lee, Hyung H.
    • Journal of Naturopathy
    • /
    • v.7 no.2
    • /
    • pp.63-69
    • /
    • 2018
  • Purpose: The purpose of this study was to investigate the effects of Bacillus fermentation broth (ENM) on the human NK cell activity, and bone matrix density, matrix content and area of hamsters fed ENM. Methods: NK cell activity was tested, and bone mineral density were measured by x-ray. Results: NK cell activity was significantly higher in the control group (644.71 pg/ml) and in the test group (1796.37 pg/ml) (p<.004). Test groups were significantly increased by 1110.37 pg/ml in the pre-test and 1796.37 pg/ml in the post-test(p<.001). Behavioral observations after feeding ENM to hamsters showed normal behavior with no difference between control and test groups. The hamster body weight of the control was 106 g at the initial and final 27 days. In the test group, the initial weight was 96.6 g and the final 27 days was 114 g. No morphological changes were observed in the X-ray photographs of the hamster hind legs. The bone matrix density was 0.059 g/cm3 in control and 0.062 g/cm3 in the test, which was increased by 0.003 g/cm3. The bone matrix content was 0.175 g in the control and 0.196 g in the test. The bone area was 2.95 cm2 in the control and 3.19 cm2 in the test, which was increased by 0.19 cm2. In the autopsy, neither the control nor the test group showed any remarkable abnormality, and each organ was normal. Conclusions: It is thought that ingestion of ENM is useful for immunity enhancement.

  • PDF

Distribution of Beneficial Bacteria in the Intestines after Enzamin Ingestion of Bacillus subtilis AK Strain Fermentation (Bacillus subtilis AK균 발효액(Enzamin)의 섭취 후 장내 유익세균의 분포조사)

  • Ryu, Seo Won;Lee, Hyung H.
    • Journal of Naturopathy
    • /
    • v.7 no.2
    • /
    • pp.27-38
    • /
    • 2018
  • Purpose: The purpose of this study was to investigate whether intestinal proliferation is promoted in beneficial intestinal bacteria or decreased in harmful bacteria before and after ingesting Bacillus fermentation broth (ENM) for 8 weeks in the 16 subjects. Method: Intestinal bacteria were identified by PCR amplification using specific 16S rRNA primers. Results: The Bifidobacterium gene index(%)(gi%) increased to 58.92% in the control group and 69.53% in the test group after the ingestion of ENM, but there was no significant difference. Lactobacillus gi% increased significantly (49.37% in the control and 66.43% in the test) (p<.029). Clostridium gi% was significantly decreased after treatment (83.16% in the control and 67.76% in the test) (p<.077). Bacteroides gi% increased significantly (12.58% in the control and 20.87% in the test) after ingesting (p<.095). Prevotella gi% increased significantly (7.55% in the control and 17.28% in the test) after ingesting (p<.005). After ingesting, the median bacteria increased significantly in the control (20.06%) and the test (35.88%) (p<.001). Conclusions: After ingestion of the ENM, the number of beneficial bacteria increased and the number of harmful bacteria Clostridium tended to decrease. This suggests that ingestion of the Bacillus fermented beverage ENM has an effect on the proliferation of intestinal bacteria.

  • PDF

Effects of the Lasater's Clinical Rubric of Debriefing in Advanced Cardiovascular Life Support Training (전문심폐소생술 교육에 Lasater의 임상판단 루브릭을 적용한 디브리핑의 효과)

  • Eun, Young;Bang, Sul-yeong
    • The Journal of the Korea Contents Association
    • /
    • v.16 no.4
    • /
    • pp.516-527
    • /
    • 2016
  • The purpose of this study was to test the effects of the Lasater's debriefing on critical thinking disposition, problem- solving skills and clinical judgement of nursing students. The study design was a nonequivalent control group non synchronized design. The subjects were 60 students for 12 groups. They were randomly assigned to the experimental group (n=30) or control group (n=30). Critical thinking and problem-solving skills were measured using a self-administered questionnaire. Clinical judgement was measured by a Lasater's clinical judgement rubric. The Results of the study was : After Lasater's debriefing, the level of students' critical thinking, problem-solving skills and clinical judgment in experimental group were higher than the level of control group. Through this experiment the rubric of Lasater debriefing is an effective tool for clinical judgment, therefore we know that the future of simulation training is needed to use the Lasater's clinical judgement rubric of debriefing in simulation training.

A STUDY ON THE DEFENSE MECHANISMS IN ADOLESCENT VICTIMS OF SCHOOL VIOLENCE (학교폭력 피해청소년의 방어기제에 관한 연구)

  • Park, Young-Sook;Shin, Jee-Yong;Jhin, Hea-Kyung
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
    • /
    • v.10 no.2
    • /
    • pp.158-168
    • /
    • 1999
  • This study was carried out to know the main defense mechanisms used by adolescent victims of school violence. Subjects of this study are composed of 41 adolescent victims(clinical group) and 40 normal adolescents(control group). Clinical group is divided into four subgroups of inpatient, outpatient, day hospital, and school groups. Used scales are Ewha Defense Mechanisms Test(EDMT) and Staittrait anger scale. Several important results are found. Adoescent victims use neurotic defense mechanisms of neurotic and mature level less frequently than normal adolescents. In clinical group day hospital adolescents use more mature defense mechanisms than outpatient adolescents. Displacement and acting out are correlated with trait and sate anger. Somatization is correlated with trait anger, and regression is correlated with state anger significantly.

  • PDF

A Clinical Effect of Electro-Acupuncture Stimulation Therapy on TMD Patients (측두하악장애환자에 대한 저주파 전자침 자극요법의 임상효과)

  • Park, Tae-Sik;Park, June-Sang;Ko, Myung-Yun
    • Journal of Oral Medicine and Pain
    • /
    • v.25 no.3
    • /
    • pp.315-323
    • /
    • 2000
  • 측두하악장애의 치료에 이용되는 저주파 전자침 자극요법의 임상적 효과를 평가하기 위하여 치료를 시행한 28명과 치료를 전혀 시행하지 않은 10명의 대조군을 대상으로 치료전과 치료 2주 후에 경혈점의 압력통각역치와 임상지수를 측정하여 다음과 같은 결론을 얻었다. 1. 환자군에서 저주파 전자침 자극요법을 시행하기 전과 후의 임상지수가 유의하게 변화하였다(P<0.001). 2. 환자군에서 저주파 전자침 자극요법을 시행하기 전과 후의 압력통각역치는 G2, G21, Li4, S2, S3, S8, Si19 및 T17에서 유의하게 증가하였다(P<0.05). 3. 대조군에서 임상지수와 압력통각역치는 실험 전후에 차이가 없었다. 4. 환자군의 임상지수가 대조군에 비하여 유의하게 변화하였다 (P<0.05). 본 연구는 저주파 전자침 자극요법의 주관적 뿐만 아니라 임상적인 효과를 보여줌으로써 측두하악장애환자의 치료에서 저주파 전자침 자극요법이 유용한 방법임을 제시하였다.

  • PDF

Development and Effects of Simulation Educational Program for Nursing Students (간호대학생들을 위한 시뮬레이션 교육프로그램 개발 및 적용효과)

  • Im, Kyung Ja;Yang, Bok Sun;Kim, Yoon Lee
    • Journal of Digital Convergence
    • /
    • v.16 no.2
    • /
    • pp.203-213
    • /
    • 2018
  • Purpose. This study was conducted to identify effects of the high fidelity simulation for nursing students. Methods. A non-equivalent quasi-experimental design was used to experimental group (N=43) and control group (N=39) for 8 weeks, 5 times from September 26 to November 9, 2013. Clinical performance was measured by using standardized patients. Critical thinking was measured through the questionnaire and clinical judgement was measured through observation by Lasater's rubric. Results. Clinical performance (F=211.15, p<.001), critical thinking (t=3.00, p<.004) and clinical judgement (t=7.60, p<.001) were significantly higher in experimental group with simulation education program than control group. Conclusion. Simulation education program were effective to improve clinical performance, critical thinking disposition and clinical judgement for nursing students.

Acupuncture, an Adjunct Therapy for Asthma: a Pilot Study Protocol of Randomized Controlled Trial (본 임상시험을 대비한 천식 침치료 무작위 대조군 예비 임상시험 프로토콜)

  • Choi, Jun-Yong;Oh, Dal-Seok;Roh, Young-Lae;Jung, Hee-Jae;Jung, Sung-Ki;Choi, Sun-Mi
    • Korean Journal of Acupuncture
    • /
    • v.25 no.3
    • /
    • pp.43-51
    • /
    • 2008
  • 배경 : 최근까지 이루어진 천식의 침치료 무작위 대조군 연구들에 의한 결과는 뚜렷한 효과를 보여주지 못하고 있다. 이러한 요인의 하나로 적절한 피험자 수를 정하기 위한 예비 임상시험의 부재가 거론되고 있다. 따라서 천식에 대한 침치료의 본 임상시험에 앞서 이의 실행 가능성 및 규모를 예측하는 예비임상시험이 필요한 상황이다. 목적 : 예비임상시험을 통해 서양의학적 치료를 받고 있는 천식환자들에 대한 침치료의 부가적 효과를 검증하기 위한 본 임상시험의 실현 가능성을 예측하기 위함. 방법 : 본 시험은 무작위 단일 맹검 대조군 평행 설계 예비 임상시험이다. 1차 평가변수는 최대 호기량 검사기로 집에서 아침, 저녁으로 매일 측정한 수치로 구해진 최대 호기 유속 일중 변동률의 1주간 평균치 변화이며 2차 평가변수는 의료기관에서 시행하는 폐기능 검사, 기준시점 호흡곤란 지수, 호흡곤란 변화에 대한 지수, 천식환자들의 삶의 질 평가를 위한 설문 등이다. 피험자 수는 총 45명으로 선정 및 제외기준을 통해서 참여하게 되며 1주간의 최대 호기 유속 기저치 평가 기간을 거친 후 진짜침 처치 군, 가짜침 처치 군, 대기군 세 군에 각각 무작위로 15명씩 할당된다. 모든 피험자에게 기존의 천식관련 약물의 사용을 허용하며, 진짜침 처치군 및 가짜침 처치군은 주 3회 4주간 해당 처치를 받고 2주 후에 각 평가 항목에 대하여 추적, 관찰하게 된다. 대기군은 기존의 천식관리를 유지하면서 2주마다 방문하여 총 6주간 평가를 받고 진짜침 처치를 4주간 받게 된다. 고찰 : 본 연구는 국내에서 최초로 이루어지는 천식에 대한 침 무작위 대조군 예비 임상시험으로 향후 적절한 피험자 수와 실행가능성을 예측할 수 있으리라 기대된다.

  • PDF

Effect of Structured Debriefing on the Learning Outcomes of Nursing Students in Simulation-based Education (간호대학생의 시뮬레이션기반 교육 시 구조화된 디브리핑 유형이 학습성과에 미치는 효과)

  • Choi, So-Eun;Kim, Hyun-Ju
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.22 no.9
    • /
    • pp.1208-1213
    • /
    • 2018
  • The study investigates how the structured debriefing method affects the learning flow, critical thinking disposition, and clinical performance of nursing students, using the Lasater Clinical Judgment Rubric (LCJR). Nursing students in the 4th grade of P University were divided into three groups, each trying out a different structured debriefing method: the experimental group - structured video debriefing using the LCJR question, the comparative group - structured oral debriefing, and the control group - structured group discussion debriefing. There was no significant difference between the three groups in learning flow (p=.640), critical thinking disposition (p=.420) and clinical performance ability (p=.360). Planning and intervention among the areas of clinical performance were significantly improved in the experimental group compared to the other two groups (p=.005). Structured debriefing when used with LCJR improves the learning flow and critical thinking disposition of students, while structured video debriefing improves clinical performance.

Effect of Strength Coaching Program for First Clinical Experience of Nursing Students (강점코칭 프로그램이 간호대학생의 첫 임상실습에 미치는 효과)

  • Hong, Ju-Young;Lee, So-Young
    • The Journal of the Convergence on Culture Technology
    • /
    • v.6 no.2
    • /
    • pp.139-143
    • /
    • 2020
  • Purpose: This study was conducted to examine the effects of a strength coaching program on nursing students' clinical competence, self esteem, and practice satisfaction. The study was designed using a nonequivalent control group pretest-post test design, and data were collected between January 7 and February 1, 2019. The participants consisted of 41, 3-year nursing students in G City who were assigned to an experimental group (n=21) or a control group (n=20). The data were analyzed using descriptive analysis, a t-test, χ2 test, and paired t-test with the SPSS/WIN 21.0 program. After receiving the strength coaching program, a difference was observed in self esteem(t=5.53, p<0.038), and practice satisfaction (t=7.66, p<0.019) of the experimental group. The results of this study indicate that the strength coaching program was effective at increasing self esteem and practice satisfaction in nursing students.

Surgical Therapy of Stanford Type A Acute Aortic Dissection -Dose intimal tear within replaced aortic segment make any difference in its clinical characteristics- (Stanford A형 급성 대동맥박리증의 외과적 치료 -내막 파열점 위치에 따른 임상경과의 차이-)

  • 조광조;우종수;성시찬
    • Journal of Chest Surgery
    • /
    • v.34 no.2
    • /
    • pp.125-132
    • /
    • 2001
  • 배경 및 목적: Stand A형 급성대동맥박리증의 박리 시발점이 수술치환부위 내에 있는 경우와 그렇지 않은 경우의 임상적 차이점을 분석하여 치료에 도움을 주고자 하였다. 방법: 1991년 3월부터 1999년 7월까지 본원에서 급성상행대동맥박리증으로 진단되어 상행대동맥치환술을 받은 40명의 환자를 대상으로 병력기록을 근거로 수술 소견 상 찢어진 부위를 발견한 환자 27명을 1군, 발견 못한 나머지 13명을 2군으로 나누고 환자의 술 전 상태와 수술소견 및 술후 경과의 임상적 차이점을 분석하였다. 결과: 1군에서 술전에 저혈압, 대동맥판막부전, 심허혈, 신부전 등이 더 많이 발생되었다. 수술 소견 상 대동맥근부 이상은 1군에서 많았다. 가성 내강 내 혈종은 2군에서 더 많이 관찰되었지만 통계적으로 유의하지는 않았다. 술후에 2군에서는 신부전이 더 많이 발생하였고 술후 출혈로 인한 재수술은 1군에서 더 많았다. 조기 수술사망은 1군에 6명으로 사망률은 22.2%이었고 2군에는 사망 례는 없었다. 결론: 본 연구를 통하여 상행대동맥에서 내막 파열이 발견된 1군에서는 2군에 비해 술전 상태가 불량하였고 대동맥판막 병변으로 수술이 복잡해져 사망률이 높다고 생각된다. 반면 원위부 하행대동맥에서 박리가 진행되어 상행대동맥으로 이어진 2군에서는 1군에 비해 순환 장애로 인해 술후에 신부전이 더 많이 발생되었다. 결론적으로 상행대동맥내막에 파열점이 없었던 군에서 수술 예후는 상행대동맥내막에 파열점이 있는 군보다 더 좋았다.

  • PDF