• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.4
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• pp.1440-1446
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• 2012

This paper presents an experimental study of heat transfer and pressure drop characteristics of supercritical carbon dioxide with PAG inside a horizontal microfin tube. Heat transfer coefficient and pressure drop gradients were measured at 10 MPa in pressure and 520 kg/$m^2s$ in mass flux with variation of PAG mass concentration from 0.06% to 2.26%. The tendencies of both heat transfer and frictional pressure drop characteristics show the same as those of pure $CO_2$ up to 0.3% in PAG mass concentration. In case of 2.26% in PAG mass concentration, measured heat transfer coefficients showed 50% lower than those of pure $CO_2$ near the pseudocritical temperature and measured frictional pressure drop gradients show 1.6 times higher in comparison with those of pure $CO_2$ at $60^{\circ}C$ in $CO_2$ bulk temperature.

• Membrane Journal
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• v.12 no.4
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• pp.216-225
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• 2002

Experimental study on the crossflow electro-microfi1tation of simulated oil emulsion waste water was carried out with polypropylene microfiltration membrane to evaluate the applicability of electrofiltration process in the treatment of oily waste water generated from many industries including nuclear field. The effects of electric field strength transmembrane pressure, crossflow velocity, and oil emulsion concentration on the permeate flux were investigated. In electro-microfiltration process using the external electric field, significant enhancement of permeate flux was achieved by diminishing membrane fouling and it was shown that considerable permeate flux can be maintained for long-term operation compared with conventional membrane filtration process without an electric field.

• Microbiology and Biotechnology Letters
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• v.40 no.4
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• pp.396-402
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• 2012

The chemical composition, anti-porcine epidemic diarrhea virus (PEDV) activity and antimicrobial activity of Artemisia dubia essential oil were evaluated in this study. Fifty eight compounds from A. dubia essential oil were identified through analysis by gas chromatography-mass spectrometry (GC-MS). The major constituents of the oil were camphor (17.18 %), germacrene-D (15.70%), trans (${\beta}-$) racaryophyllene (6.79%), ene thujones (6.57%), 1, 8-cineole (5.94%) and camphene (5.08%). The essential oil was evaluated for antiviral activity against PEDV in Vero cells using a cytopathic effect (CPE) reduction method. The oils actively inhibited PEDV replication with a 50% inhibitory concentration ($IC_{50}$) of 43.7 ${\mu}^3/mL$. The 50% cytotoxicity concentration ($CC_{50}$) of the oils was over 100 ${\mu}/mL$ and the derived therapeutic index was >2.3. Similar analysis of the ribavirin revealed that they have a relatively weaker efficacy when compared to the oils. The antimicrobial activity of the essential oil against 5 microorganisms was evaluated by the disc diffusion method. The essential oil exhibited antimicrobial activity against 5 tested microorganisms with a clear zone of 8-22 mm. Among the tested microorganisms, Streptococcus pyogenes was the most sensitive and Candida albicans the least. Therefore, in can be concluded that essential oils of A. dubia may have interesting applications for microbial control or the control of PEDV-derived diseases.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.41 no.4
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• pp.383-389
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• 2015

In this study, we investigated the inhibitory effect on melanin synthesis of Ginkgo biloba seed oil. The results showed 9.96% inhibitory effect scavenging activity on DPPH and showed a value of 1.33 mM of $FeSO_4$ at a concentration of 0.06% in DMSO by using FRAP assay. G. biloba seed oil inhibited tyrosinase activity up tp 37.72% and suppressed the biosynthesis melanin up to 48.02% at 0.06% in B16/F10 mouse melanoma cell. In G. biloba seed oil treated group tyrosinase, TRP-1, TRP-2 and MITF gen expression levels significantly decreased compared to the contral group at a concentration of 0.04% and 0.06%. In conclusion, these results indicated that G. biloba seed oil extract have a good antimelanogenetic effects.

• Journal of the Institute of Convergence Signal Processing
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• v.24 no.3
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• pp.153-159
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• 2023

As research results showed that ozonated olive oil has excellent therapeutic effects on skin diseases, attempts were made to develop cosmetics manufacturing technology using ozone. Ozone is harmful to the human body, so a separate facility must be prepared to manufacture ozonated olive oil as a cosmetic raw material. The manufacturing device developed in this study was designed as an optimized process for manufacturing cosmetics while ensuring the safety of workers involved in production. To verify the ozonated olive oil produced from the implemented device, a toxicity test was conducted on animals. After applying ozonated oil (high concentration) to the rabbit's back for 24 hours, mortality, general symptoms and symptoms were measured. A skin irritation evaluation was performed. As a result of the experiment, as a result of evaluating the test substance treatment area after a certain period of time, it was confirmed that no skin irritation was observed in all animals, confirming the safety of the ozonated oil production process and the safety of the product.

• Journal of the Korean Applied Science and Technology
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• v.35 no.3
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• pp.744-756
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• 2018

The purpose of this study was to investigate the anti-inflammatory effect and the antimicrobial activity to skin flora of essential oil from rosemary that naturally grown in Jeju. rosemary essential oil was extracted by water distillation essential oil extraction method. In order to confirm the anti-inflammatory activity of rosemary essential oil, it was confirmed that the production of NO and $PGE_2$ induced by LPS in RAW 264.7 cells was inhibited in a concentration-dependent manner. Western blot analysis showed that the expression of iNOS and COX-2, which are biosynthetic enzymes, decreased in a concentration-dependent manner. In addition, production of $TNF-{\alpha}$ and IL-6 the pro-inflammatory cytokines were inhibited. Antimicrobial activities of three S. epidermidis and three P. acnes strains including two antibiotic resistant strains were observed in paper disc method and MIC and MBC tests showed inhibition of bacterial growth and death. From the results of the experiment, we confirmed that rosemary essential oil has the anti-inflammatory and antimicrobial efficacy and it could be used as a cosmetic and skin care material in the future.

• Applied Chemistry for Engineering
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• v.26 no.3
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• pp.341-346
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• 2015

In this study, poly ${\varepsilon}$-caprolactone(PCL) microcapsules containing lemongrass oil was prepared by the solvent evaporation method. Effects of concentrations of PCL and poly vinyl alcohol (PVA) as well as stirring speeds when preparing microcapsules were investigated. Specific peaks of lemongrass oil in PCL microcapsules at 1600 and $2900cm^{-1}$ were observed by FT-IR. The particle size and shape of microcapsules were also measured by polarizing microscope and optical microscopy. The average particle size of microcapsules decreased with increasing the stirring rate. At the stirring speed of 1500 rpm, and 1 wt% of each PCL and PVA concentrations, the smallest particles were formed. Collection efficiencies of lemongrass oil of 77.5% and 69.5% were obtained when 1.5 wt% of PCL and 2 wt% of PVA were used, respectively. In addition, the release behavior and antioxidant activity of lemongrass oil from PCL microcapsules were examined using UV-Vis spectrophotometry. When 0.5 wt% PCL and 2.0 wt% PVA were used with the slow stirring rate, microcapsules showed a fast release rate. The characteristics of antioxidant activity exhibited similar to that of the release behavior.

• Korean Journal of Clinical Laboratory Science
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• v.49 no.3
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• pp.256-262
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• 2017

Essential oil from herb is known to exert pharmacological effects on the human body. In this study we investigated the antibacterial activity of 4 essential oils (teetree, rosemary, melisa, and lavender), as well as the blended mixture oil of teetree, rosemary, and melisa (TRM) on three bacteria, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. Antibacterial analysis was performed using the standard disk diffusion method, and minimum inhibition concentration was determined by the broth microdilution method with different concentrations of essential oils (0.5, 1, 2 and 3 mg/mL). After incubation at $37^{\circ}C$ for 24 h, the antibacterial activity was assessed by measuring the zone of growth inhibition surrounding the disks. Herb oil with the inhibition zones showed varied values ranging from6 to 25 mm. However, the components of herb oil of TRM are as highly active as the teetree oil against pathogens, generating large inhibition zones for both gram negative and positive bacteria (13~22 mm and 8 mm inhibition zones). In the analysis for MIC, TRM showed growth-inhibitory effects at 0.0625% for S. aureus and E. coli, and 1.25% for P. aeruginosa. This result demonstrated that the anti-microbial activity of TRM was greater than a single herb oil, including oxacillin, rosemary, and teetrea. As a single herb oil, both rosemary and teetrea also had an anti-microbial effect by itself, and we can expect that the blended oil mixture may exert a synergistic effect against multidrug resistant bacteria, suggesting its future application in natural preservative agents for health food and cosmetics.

• Asian Journal of Turfgrass Science
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• v.26 no.1
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• pp.35-43
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• 2012

These studies were carried out to ascertain the effects of paraffin oil on prolongation of the green leaf color period in Zoysiagrass. Fifty-fold diluted 98% paraffin oil treatment obtained the lowest reduction rate of green color. In early October we sprayed 50-fold, 100-fold and 200-fold diluted 98% paraffin oil in a Zoysia japonica field in Hapcheon of Gyeongnam and Sangju of Gyeongbuk and in a Z. matrella field in Gumjung of Busan and Anseong of Gyeonggii. Leaf color maintained for 60 days after treatment in Zoysia japonica. Leaf color remained for 60 days after treatment in Anseong, Hapcheon and Sangju when treated in the mid-October. Chlorophyll content was higher in paraffin oil treatment areas than in control areas in early October. Weight reduction rate was lower in the paraffin oil treated than in untreated leaves of Zoysiagrass when sprayed in Gumjung and Anseong in early October and mid-October, respectively. The chlorophyll content in leaves of Z. japonica was increased by increasing the spray volume of paraffin oil in the same dose treated in Lexington, Kentucky, USA. Paraffin oil can be used to prolongate of Zoysiagrass leaf color.

• Journal of Life Science
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• v.29 no.2
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• pp.223-230
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• 2019

Ozone is a gaseous molecule able to kill microorganisms, such as yeast, fungi, bacteria, and protozoa. However, ozone gas is unstable and cannot be used easily. In order to utilize ozone properly and efficiently, plant oil can be employed. Ozone reacts with C-C double bonds of fatty acids, converting to ozonized oil. In this reaction, ozonide is produced within fatty acids and the resulting ozonized oil has various biological functions. In this study, we showed that ozonized oil has antimicrobial activity against fungi and bacteria. To test the antimicrobial activity of ozonized oil, we produced ozonized olive oil. Ozonized olive oil was applied to Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans. Antimicrobial activity was assayed using the disk diffusion method following the National Committee for Clinical Laboratory Standards. Minimal inhibitory concentrations (MIC) were 0.25 mg for S. aureus, 0.5 mg for S. epidermidis, 3.0 mg for P. aeruginosa, and 1.0 mg for E. coli. Gram positive bacteria were more susceptible than Gram negative bacteria. We compared growth inhibition zones against S. aureus and MRSA, showing that the ozonized olive oil was more effective on MRSA than S. aureus. Furthermore, the ozonized olive oil killed C. albicans within an hour. These data suggested that ozonized olive oil could be an alternative drug for MRSA infection and could be utilized as a potent antimicrobial and antifungal substance.