• The Journal of the Convergence on Culture Technology
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• v.9 no.5
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• pp.375-383
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• 2023

The purpose of the study was to analyze research trends of Korean articles on early childhood teachers' empowerment published in 2005 through 2022. For this purpose, 87 articles were selected and analyzed by years, research methods, and research themes. As results, Korean article on early childhood teachers' empowerment was first published in 2005 and then continuously conducted every year until 2022. In terms of research methods, 'quantitative research', 'survey questionnaire', and 'analysis of effects' were shown the most. In addition, 'early childhood teacher' and 'daycare center' showed more distribution and 'the scale developed by Short and Rinehart' was most used. As research themes, the most studies have investigated 'influence of empowerment'. Based on the results, we discuss and suggest on future research.

• Journal of Life Science
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• v.33 no.5
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• pp.429-435
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• 2023

Epidemiological studies suggest that maternal infection, maternal stress, and environmental risk factors during pregnancy increase the risk of brain development abnormalities associated with cognitive impairment in the offspring and increase susceptibility to schizophrenia and autism spectrum disorder. Several animal models have demonstrated that maternal immune activation (MIA) is sufficient to induce abnormal brain development and behavioral defects in the fetus. When polyinosine:polycytodylic acid (poly I:C) or lipopolysaccharide (LPS), which is commonly used in maternal immune activation animal models, was introduced into a pregnant dam, an increase in pro-inflammatory cytokines and microglial activity was observed in the offspring's brain. Microglia are brain-resident immune cells that play a mediating role in the central nervous system, and they are responsible for various functions, such as phagocytosis, synapse formation and branching, and angiogenesis. Several studies have reported that microglia are activated in MIA offspring and influence offspring behavior through interactions with various cytokines. In addition, it has been reported that they play an important role in brain circuits through interactions with neurons and astrocytes. However, there is controversy concerning whether microglia are essential to brain development or lead to behavioral defects, and the exact mechanism remains unknown. Therefore, for the potential diagnosis and treatment of brain developmental disorders, a functional study of microglia should be conducted using MIA animal models.

• Journal of Life Science
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• v.33 no.6
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• pp.455-462
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• 2023

During pregnancy, maternal immune activation (MIA) from infection increases the risk of neurodevelopmental diseases, including schizophrenia and autism spectrum disorders. MIA induced by polyinosinic-polycytidylic acid (poly (I:C)) and lipopolysaccharide (LPS) in animal experiments has led to offspring with abnormal behaviors and brain development. In addition, it has recently been reported that microglia, which reside in the brain and function as immune cells, play an important role in behavioral abnormalities and brain development in MIA-induced offspring. However, the underlying mechanism remains unclear. In this study, we investigated whether microglia-specific inhibition of GPR56, a member of the G protein-coupled receptor (GPCR) family, causes behavioral abnormalities in brain development. First, MIA induction did not affect the microglia population, but when examining the expression of microglial GRP56 in MIA-induced fetuses, GPR56 expression was inhibited between embryonic days 14.5 (E14.5) and E18.5 regardless of sex. Furthermore, microglial GPR56-suppressed mice showed abnormal behaviors in the MIA-induced offspring, including sociability deficits, repetitive behavioral patterns, and increased anxiety levels. Although abnormal cortical development such as that in the MIA-induced offspring were not observed in the microglial GPR56-suppressed mice, their brain activity was observed through c-fos staining. These results suggest that microglia-specific GPR56 deficiency may cause abnormal behaviors and could be used as a biomarker for the diagnosis and/or as a therapeutic target of behavioral deficits in MIA offspring.

• Applied Microscopy
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• v.36 no.2
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• pp.119-130
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• 2006

To investigate the role of myelin-associated glycoprotein (MAG) in the normal aging process, aging-related morphometric and ultrastructural analyses of the MAG-positive (MAG-(+)) oligodendrocytes were carried out in the cerebral cortex of the Sprague-Dawley rats. In the aged rats, the density of MAG-(+) oligodendrocytes was significantly decreased in the cortical layer (IV-VI) compared with that of the adult rats. However, the percentage of medium and dark types of oligodendrocytes was significantly increased by aging. In the aged rats, the mean nuclear area of the MAG-(-) oligodendrocytes was interestingly reduced compared with that of MAG-(+) oligodendrocytes. In addition, MAG immunoreactive products were markedly decreased in the medium-dark type of oligodendroglial cytoplasm and processes, and were scarcely localized in the dark type of oligodendrocytes of the aged rats. These results suggest that degeneration of oligodendrocytes-myelin system by aging is associated with down regulation of MAG, and that may contribute to further understanding of the biology of MAG in the oligodendrocytes-myelin system.

• The Journal of the Korea Contents Association
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• v.17 no.8
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• pp.263-273
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• 2017

Although this research puts the emphasis on the importance of the personality education, and lacks the understanding of the early childhood educator about the personality education, and essentially the content analysis of the direction of the operation of the personality education hasn't been performed. Therefore through the research study once again we collected the opinion of the early childhood educator about the personality education. As the object of the investigation, we questioned 208 teachers who work in the Daycare Center in the S city, and applied the SPSS 18.0 program. The result is as the following. First, there was a lot of concern in the understanding of the early childhood educator about the personality education, and that it was in need. The reason for emphasizing the personality education appears to be the "Individual Egoism", and the "Parental Value" as the factor of influence, and "Whole People Human Development and Health Promotion" as a factor of helping, and "Courage" as the inner information of the information of the personality education, and "Manner" as the outer information. Secondly, more than the majority was carrying out the personality education in the real state of the early childhood educator on the personality education and it happens to be that the instructional material is the "Material related to the personality education", "Conversation" as the teaching learning method, "Once per week" as number of times, "Within 30 minutes" as lead time, "Teacher in Charge" as the host, and "Uncooperative parents" as the difficulty. Lastly the accurate time of demanding the early childhood educator about the personality education happens to be from "Infancy", and the teaching method is "Teaching by making a connection with the family", and that "Leading by example of the teacher" is the factor of consideration.

• Journal of the korean academy of Pediatric Dentistry
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• v.37 no.3
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• pp.308-316
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• 2010

Odontoblasts are anchorage dependent cells adhering to a substrate via cell adhesive molecules. Receptor ligands such as integrins bind to these proteins and are known to function as signal transduction molecules in a series of critical recognition events of cell-substratum. The aim of this study is to examine the interaction of odontoblast (MDPC-23 cell) with type I Col and the effect of TGF-${\beta}1$ and TNF-$\alpha$ on the expression of cell adhesion molecules. In this study, MDPC-23 cells adhered to type I Col dose-dependently. Immunofluorescence data demonstrated that integrin ${\alpha}1$, ${\alpha}2$ and CD44 were expressed on cell surface, and FAK and paxillin were localized in focal adhesion plaques in MDPC-23 cells adhesion to Col. Cytokine TGF-${\beta}1$ increased the adhesion of MDPC-23 cells to Col and the expression level of integrin ${\alpha}1$, 4{\alpha}2$ and chondroitin sulfate on MDPC-23 cells. RT-PCR data demonstrated that cytokine TGF-${\beta}1$ increased the amount of integrin ${\alpha}1$ mRNA in MDPC-23 cells. Therefore, MDPC-23 cells adhere to collagen type I Col and expressed a complex pattern of integrins and proteoglycans, including ${\alpha}1$, ${\alpha}2$, chondroitin sulfate and CD44 detected by immunoblotting and immunofluorescence assay. TGF-${\beta}1$ treatment enhanced the expression of adhesion molecules such as integrin ${\alpha}1$, ${\alpha}2$ and chondroitin sulfate.

• Journal of Conservation Science
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• v.37 no.5
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• pp.557-566
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• 2021

We investigated the properties of Korean traditional animal glue which are associated with the use of different parts of cattle hide and extraction conditions. Both average molecular weight(Mw, Mz) and polydispersity (PDI) of the animal glue increased with extraction time, whereas only PDI decreased after 48h. There were no differences in the average molecular weight and PDI for the different cattle hide parts used, although a individual difference was observed with regard to total molecular weight. Differences in extracts over time were compared by investigating the amide regions representing the gelatien component of the animal glue. The triple helix structure of the belly skin deteriorated in a manner proportional to the extraction time, and differences were observed for each cattle hide part. The yellowness increased with the extraction time; however, the viscosity was not proportional to the average change in molecular weight. This study has some limitations because of difficulties in the quality control of cases where small amounts of glue were extracted as small differences might impact the overall results considerably. Further research exploring various extraction conditions is required to ensure the prodiction of traditional animal glue with optimum qualities.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.12
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• pp.570-577
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• 2020

This study is aimed at figuring out the influence of early childhood teachers' playfulness and sensitivity on play teaching efficacy. The subjects of the study were 262 early childhood teachers working in kindergarten and day care centers located in J City. The instruments were the Adult Playfulness Scale, the Sensitivity Scale, and the Play Teaching Efficacy Scale. The collected data were analyzed by using SPSS. In order to find out the general background of the early childhood teachers, frequency and percentage were used. In addition, in order to assess the relationships among playfulness, sensitivity, and the play teaching efficacy of an early childhood teacher, Pearson's correlation analysis was carried out. Lastly, for examination of the effects and a relative explanation of the effects of playfulness and sensitivity on play teaching efficacy in early childhood teachers, a multiple regression analysis was conducted. The results of this study are as follows. First, there was positive correlation among playfulness, sensitivity, and play teaching efficacy in the early childhood teacher. Second, play teaching efficacy of early childhood teachers was influenced by their playfulness and sensitivity. In conclusion, the significance of this study is that there was a significant correlation among playfulness, sensitivity, and play teaching efficacy in early childhood teachers, and that both of the first two variables were factors influencing play teaching efficacy.

• Journal of Labour Economics
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• v.41 no.1
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• pp.1-38
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• 2018

The paper investigates the determinants of female, maternal, and male employment in a comparable setting using an unbalanced panel data of 29 OECD countries from 2000-2013. Our empirical results show that early childhood childcare and education (ECEC) is positively associated with female employment. Furthermore, we find that ECEC does not hurt male employment. We also find that tax rates on the second earner are negatively associated with male employment as well as female employment. The estimated coefficients of ECEC, social expenditure, tax rates, and tertiary education attainment rates in maternal employment regressions are much larger in the absolute value than those in female employment regressions. Policy implications of our analysis are that an expansion of ECEC, a lower tax on secondary earner, and education are key to promote the total employment as well as female employment.

• Korean Journal of Childcare and Education
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• v.12 no.1
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• pp.103-121
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• 2016

The purpose of this study was to examine the impact of the listening competence of early childhood teachers on their teacher-parent communication difficulties and teacher-child interaction in an attempt to provide some information on the development of the listening competence of early childhood teachers. Three hundred and twenty two early childhood teachers participated in the study and descriptive, correlation, multiple regression analysis were conducted. The results are as follows: First, listening competence had a statistically significant negative correlation with teacher-parent communication difficulties. Second, among the sub-factors of listening competence, comprehending and interpreting, and responding exerted a statistically significant negative influence on teacher-parent communication difficulties. Third, listening competence had a statistically significant positive correlation with teacher-child interaction. Fourth, among the sub-factors of listening competence, responding, comprehending and interpreting, analyzing and evaluating exerted a statistically significant positive influence on teacher-child interaction.