• Title/Summary/Keyword: 신호효과

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Current Perspectives on the Effects of Plant Growth-promoting Rhizobacteria (식물생장촉진 근권미생물의 영향에 대한 연구 현황 및 전망)

  • Le, Thien Tu Huynh;Jun, Sang Eun;Kim, Gyung-Tae
    • Journal of Life Science
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    • v.29 no.11
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    • pp.1281-1293
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    • 2019
  • The rhizosphere is the active zone where plant roots communicate with the soil microbiome, each responding to the other's signals. The soil microbiome within the rhizosphere that is beneficial to plant growth and productivity is known as plant growth-promoting rhizobacteria (PGPR). PGPR take part in many pivotal plant processes, including plant growth, development, immunity, and productivity, by influencing acquisition and utilization of nutrient molecules, regulation of phytohormone biosynthesis, signaling, and response, and resistance to biotic- and abiotic-stresses. PGPR also produce secondary compounds and volatile organic compounds (VOCs) that elicit plant growth. Moreover, plant roots exude attractants that cause PGPR to aggregate in the rhizosphere zone for colonization, improving soil properties and protecting plants against pathogenic factors. The interactions between PGPR and plant roots in rhizosphere are essential and interdependent. Many studies have reported that PGPR function in multiple ways under the same or diverse conditions, directly and indirectly. This review focuses on the roles and strategies of PGPR in enhancing nutrient acquisition by nutrient fixation/solubilization/mineralization, inducing plant growth regulators/phytohormones, and promoting growth and development of root and shoot by affecting cell division, elongation, and differentiation. We also summarize the current knowledge of the effects of PGPR and the soil microbiota on plants.

New Approaches to the Control of Pathogenic Oral Bacteria (바이오필름을 생성하는 병원성 구강 세균을 제어하는 새로운 접근법)

  • Cho, Soo Jeong
    • Journal of Life Science
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    • v.31 no.1
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    • pp.100-108
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    • 2021
  • In the oral cavity, there are hundreds of microbial species that exist as planktonic cells or are incorporated into biofilms. The accumulation and proliferation of pathogenic bacteria in the oral biofilm can lead to caries and periodontitis, which are typical oral diseases. The oral bacteria in the biofilm not only can resist environmental stress inside the oral cavity, but also have a 1,000 times higher resistance to antibiotics than planktonic cells by genes exchange through the interaction between cells in the oral biofilm. Therefore, if the formation of oral biofilm is suppressed or removed, oral diseases caused by bacterial infection can be more effectively prevented or treated. In particular, since oral biofilms have the characteristic of forming a biofilm by gathering several bacteria, quorum sensing, a signaling system between cells, can be a target for controlling the oral biofilm. In addition, a method of inhibiting biofilm formation by using arginine, an alkali-producing substrate of oral bacteria, is used to convert the distribution of oral microorganisms into an environment similar to that of healthy teeth or inhibit the secretion of glucosyltransferase by S. mutans to inhibit the formation of non-soluble glucans. It can be a target to control oral biofilm. This method of inhibiting or removing the oral biofilm formation rather than inducing the death of pathogenic bacteria in the oral cavity will be a new strategy that can selectively prevent or therapeutic avenues for oral diseases including dental caries.

An Exploratory Study on Sales and Operations Planning as SCM Supporting Tool (공급망 관리 지원도구로서의 S&OP 운영에 관한 탐색적 연구)

  • Park, Seong Taek;Kim, Tae Ung;Kim, Mi Ryang
    • Journal of Digital Convergence
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    • v.19 no.2
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    • pp.93-103
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    • 2021
  • S&OP(Sales and Operations Planning) is an ongoing process of periodic planning, reviewing, and evaluation through the involvement of all key stakeholders. Within this process, performance is regularly reviewed and early warning signals are generated, so that the company can react quickly to changing market and operational environment. This paper presents a framework for effective S&OP for fair alignment, accountability, teamwork, visibility, and risk management. This framework focuses on supply chain information governance, level of information sharing through S&OP, role of S&OP as coordination mechanism, APS effectivesness as a planning tool and SCM performance. In addition, a brief case study on the operating characteristics of S&OP at three Korean firms is presented. Implications of the study finding are also provided. It will also make companies that are considering the introduction of S&OP aware of the importance of S&OP, which will provide practical guidelines for the introduction of S&OP.

Fucoidan Stimulates Glucose Uptake via the PI3K/AMPK Pathway and Increases Insulin Sensitivity in 3T3-L1 Adipocytes (후코이단의 3T3-L1 지방세포에서 PI3K/AMPK 경로를 통한 포도당 흡수 촉진 및 인슐린 민감성 증진 효과)

  • Lee, Ji Hee;Park, Jae Eun;Han, Ji Sook
    • Journal of Life Science
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    • v.31 no.1
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    • pp.1-9
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    • 2021
  • Brown seaweeds have been shown to decrease blood glucose levels and improve insulin sensitivity previously. In this study, we investigated the effect of fucoidan, a complex polysaccharide derived from brown seaweeds, on glucose uptake to improve insulin resistance, and examined its mechanism of action in 3T3-L1 adipocytes. We observed that fucoidan significantly increased glucose uptake and it was related to an increased expression of plasma membrane-glucose transporter 4 (PM-GLUT4) in 3T3-L1 adipocytes. Fucoidan treatment increased the activation of phosphatidylinositol-3-kinase (PI3K) and the phosphorylation of insulin receptor substrate 1 (IRS1tyr) compared with that of the control cells. Fucoidan also promoted the phosphorylation of Akt and protein kinase C (PKC)-λ/ζ compared to that of the control cells. Moreover, fucoidan significantly upregulated acetyl-CoA-carboxylase (ACC) and adenosine monophosphate - activated protein kinase (AMPK) phosphorylation. As a result, translocation of GLUT4 was significantly enhanced in 3T3-L1 adipocytes, which significantly promoted glucose uptake via the PI3K/AMPK pathways. The elevation of glucose uptake by fucoidan was blocked by inhibitor of PI3K and inhibitor of AMPK in 3T3-L1 adipocytes. These findings indicate that fucoidan might ameliorate glucose uptake through GLUT4 translocation to the plasma membrane by activating the PI3K/Akt and AMPK pathways in 3T3-L1 adipocytes. Fucoidan is thought to be of high material value to diabetes treatments and functional foods.

Analysis on Normal Ionospheric Trend and Detection of Ionospheric Disturbance by Earthquake (정상상황 전리층 경향 분석 및 지진에 의한 전리층 교란검출)

  • Kang, Seonho;Song, Junesol;Kim, O-jong;Kee, Changdon
    • Journal of Advanced Navigation Technology
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    • v.22 no.2
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    • pp.49-56
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    • 2018
  • As the energy generated by earthquake, tsunami, etc. propagates through the air and disturbs the electron density in the ionosphere, the perturbation can be detected by analyzing the ionospheric delay in satellite signal. The electron density in the ionosphere is affected by various factors such as solar activity, latitude, season, and local time. To distinguish from the anomaly, therefore, it is required to inspect the normal trend of the ionosphere. Also, as the perturbation magnitude diminishes by distance it is necessary to develop an appropriate algorithm to detect long-distance disturbances. In this paper, normal condition ionosphere trend is analyzed via IONEX data. We selected monitoring value that has no tendency and developed an algorithm to effectively detect the long-distance ionospheric disturbances by using the lasting characteristics of the disturbances. In the end, we concluded the $2^{nd}$ derivative of ionospheric delay would be proper monitoring value, and the false alarm with the developed algorithm turned out to be 1.4e-6 level. It was applied to 2011 Tohoku earthquake case and the ionospheric disturbance was successfully detected.

Improvement of LMS Algorithm Convergence Speed with Updating Adaptive Weight in Data-Recycling Scheme (데이터-재순환 구조에서 적응 가중치 갱신을 통한 LMS 알고리즘 수렴 속 도 개선)

  • Kim, Gwang-Jun;Jang, Hyok;Suk, Kyung-Hyu;Na, Sang-Dong
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.9 no.4
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    • pp.11-22
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    • 1999
  • Least-mean-square(LMS) adaptive filters have proven to be extremely useful in a number of signal processing tasks. However LMS adaptive filter suffer from a slow rate of convergence for a given steady-state mean square error as compared to the behavior of recursive least squares adaptive filter. In this paper an efficient signal interference control technique is introduced to improve the convergence speed of LMS algorithm with tap weighted vectors updating which were controled by reusing data which was abandoned data in the Adaptive transversal filter in the scheme with data recycling buffers. The computer simulation show that the character of convergence and the value of MSE of proposed algorithm are faster and lower than the existing LMS according to increasing the step-size parameter $\mu$ in the experimentally computed. learning curve. Also we find that convergence speed of proposed algorithm is increased by (B+1) time proportional to B which B is the number of recycled data buffer without complexity of computation. Adaptive transversal filter with proposed data recycling buffer algorithm could efficiently reject ISI of channel and increase speed of convergence in avoidance burden of computational complexity in reality when it was experimented having the same condition of LMS algorithm.

A Convergence Study on the Reduction of Noise and Streak Artifacts in Shoulder Joint Computed Tomography (어깨관절 컴퓨터 단층 검사 시 발생하는 노이즈 및 줄무늬 인공물 감소에 대한 융합 연구)

  • Jang, Hyon-Chol;Cho, Pyong-Kon
    • Journal of Convergence for Information Technology
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    • v.11 no.7
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    • pp.189-194
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    • 2021
  • The purpose of this study was to investigate the effect of reducing noise and streaking artefacts by applying the Boost3D algorithm in the case of noise and streaking artifacts generated during computed tomography of the shoulder joint. A phantom study using a thoracic phantom including shoulder joint and clinical evaluation were conducted through shoulder joint images of 35 patients who underwent computed tomography of the shoulder joint from September 2020 to October 2020. The evaluation was divided into groups before and after the application of the Boost3D algorithm, and the noise values, signal to noise ratio, and mean to standard deviation ratio values were analyzed. Both noise values and mean to standard deviation ratio values analyzed in phantom image evaluation and clinical image evaluation were statistically significantly lower in the group after Boost3D was applied (p<0.05). Through this study, it was found that noise and streak artifacts were reduced through the application of Boost3D, and the mean to standard deviation ratio was high, which can be judged as an excellent image. If the Boost3D algorithm is used for computed tomography of the shoulder joint, it is thought that excellent images can be obtained with reduced noise and streaking artifacts that may occur in the shoulder joint area.

Anti-cancer effects of Salicornia herbacea extract in OVCAR-3 cells by induction of apoptosis pathway (함초 추출물의 세포사멸 유도에 의한 난소암세포에서 항암 효과)

  • La, Yu Ri;Lee, You Rim;Lee, Dong Seok;Kim, Soo Hwan;Lee, Hyeong Seon
    • Korean Journal of Food Science and Technology
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    • v.53 no.1
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    • pp.34-39
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    • 2021
  • This study investigated the anti-cancer effects of Salicornia herbacea L. fractions in human ovarian cancer cells (OVCAR-3). S. herbacea powder was extracted with 95% EtOH and sequentially fractionated with hexane, dichloromethane (DCM), ethyl acetate, butanol, and H2O. Further, the growth inhibitory effects of the six fractions were determined using the MTS assay. The DCM fraction dramatically decreased cell viability. Similarly, the cell cycle was arrested at the subG1 phase in DCM-treated cells. To confirm apoptosis, the cells were stained with annexin V/FITC-PI solution. Total, early, and late apoptotic cells were significantly increased in the DCM fraction. The mRNA expression of Bcl-2 was reduced, whereas the pro-apoptotic factors Bax and Bak were increased in DCM fraction-treated cells. These results indicated that the DCM fraction in S. herbacea exhibited strong apoptotic effects through the p53-dependent signaling pathway.

Does sports intelligence, the ability to read the game, exist? A systematic review of the relationship between sports performance and cognitive functions (게임을 읽는 머리, 스포츠 지능이 존재하는가? 스포츠 수행과 관련된 인지기능에 관한 문헌고찰)

  • Yongtawee, Atcharat;Park, Jin-Han;Woo, Min-Jung
    • Journal of the Korea Convergence Society
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    • v.12 no.3
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    • pp.325-339
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    • 2021
  • The purpose of the study is to examine sports-related cognitive functions through a systematic review and to suggest effective instruments to measure the cognitive functions. The present study was conducted based on the systematic review and meta-analysis protocol-the PRISMA. Of 429 articles searched through keywords from 2008 to 2020, 45 articles that met the selection criteria were analyzed. It was revealed that athletes had better cognitive functions than non-athletes, that the higher the sports expertise was, the higher the cognitive functions, and that there were differences in cognitive functions according to the sport types. The primary cognitive functions related to sports performance summarized as executive functions (inhibition ability, cognitive flexibility), information processing speed, spatial ability, and attention. As tasks for measuring each cognitive function, a stop signal task for inhibition ability, a design flexibility task for cognitive flexibility, a simple and choice reaction time test for information processing, a mental rotation task for spatial ability, and an attention network test for attention are appropriate.

Evaluation of the efficacy of modified Samultang in female menopausal animal models using ovarian resection rats (난소절제 랫드를 이용한 여성갱년기 동물모델에서 변형 사물탕의 효능평가)

  • Hwang, Seonghee;Park, Sunyoung;Shin, Yong Kook
    • Journal of the Korea Convergence Society
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    • v.13 no.4
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    • pp.573-582
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    • 2022
  • In order to develop samultang with reduced side effects, modified samultang using omija was oral administered to rats with ovarian resection, and changes in evaluation indicators of functional efficacy in women's menopause were measured. In weight gain, relative weight of uterus and vagina, blood lipid-related indicators, and changes in blood estradiol, there was no statistically significant improvement effect in modified Samultang compared to the control group. However, the expression of estrogen receptor alpha and beta in intrauterine tissue tended to increase, and the expression of phosphorylated ERK, which is known to be involved in estrogen receptor signaling, showed a significant increase in activation in ERK and AKT. The expression amount of phosphorylation AKT was not significant, but showed an increasing tendency. Even though the test substance was administered in a relatively small dose, it is judged that the test substance modified Samultang has the ability to activate estrogen receptor. In the future, it is expected that it can be used as a useful natural mixture to show the efficacy of samultang with fewer gastrointestinal disorders.