• Title/Summary/Keyword: 시간 가역성

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Porous Glass Electroosmotic Pumps Reduced Bubble Generation Using Reversible Redox Solutions (가역적 산화환원반응 용액을 이용하여 기포 발생을 줄인 다공성 유리막 전기삼투 펌프)

  • Kwon, Kil-Sung;Kim, Dae-Joong
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.7
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    • pp.753-757
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    • 2012
  • This paper presents the performance of a porous glass electroosmotic pump using an iodide/triiodide aqueous solution. The porous glass electroosmotic pump is characterized in terms of the flow rate and voltage. The flow rate and voltage increases linearly with current. A point where the voltage significantly increases is observed owing to an excess in redox capacity. The transition time monotonously decreases with current. The normalized flow rate (flow rate per membrane surface area) is used to compare previous results with results obtained in this study. The normalized flow rate of porous glass frits is three times higher than that of Nafion 117.

Differentiation of Sorptive Bindings of Some Radionuclides with Sequential Chemical Extractions in Sandstones (순차적화학추출법을 사용한 방사성핵종의 사암에 대한 수착유형 평가)

  • Park, Chung-Kyun;Hahn, Pil-Soo;Park, Hun-Hwee
    • Nuclear Engineering and Technology
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    • v.26 no.4
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    • pp.461-470
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    • 1994
  • Sorption experiments of $^{60}$ Co, $^{85}$ Sr. and $^{137}$ Cs onto sandstone particles in a batch were carried out to investigate the migration mobility. Sorption kinetics and reversibility as well as sorption mechanisms were examined. Sorption reaction occurred mostly within 10 hours on the outer surface of the sandstone particle but diffusion into the inner surface of the mineral has still occurred after that time. In order to distinguish sorption types of radionuclides, a sequential chemical extraction was introduced. The sorbed radionuclides were then extracted by applying different solutions of synthetic groundwater, CaCl$_2$, KCl and KOX-HA Especially KCl is adopted to extract the ion-exchanged cesium. Sorption types considered are reversible sorption under groundwater condition, ion exchange, association with ferro-manganese oxides or oxyhydroxides, and irreversible fixation. Strontium sorbs onto the sandstone surface mainly by fast and reversible ion exchange reaction. However, cobalt and cesium do not sorb by simple process. The main sorptive binding of cobalt was the association with ferro-manganese oxides and the secondary one was irreversible fixation. Diffusion into the lattice of minerals controlled the sorption rate of cobalt The main sorptin type of cesium was irreversible fixation, while ion exchange reaction was the secondary importance. Hence the oreder of migration mobility for the three radionuclides was Sr$^{2+}$ > Co$^{2+}$ > Cs$^{+}$ in the sandstones.

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Role of Redistribution and 24 Hour Reinjection Images to assess Myocardial Viability in Patients with Acute Myocardial Infarction (급성심근경색환자의 심근생존능 평가에 있어서 T1-201 재분포영상과 24시간 재주사영상의 역할)

  • Yoon, Seok-Nam;Pai, Moon-Sun;Park, Chan-H.;Yoo Myung-Ho;Choi, Byung-Il William
    • The Korean Journal of Nuclear Medicine
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    • v.32 no.4
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    • pp.325-331
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    • 1998
  • Purpose: We evaluated the importance of redistribution and 24 hour reinjection images in T1-201 SPECT assessment of myocardial viability after acute myocardial infarction (AMI). Materials and Methods: We performed dipyridamole stress-4 hour redistribution-24 hour reinjection T1-201 SPECT in 43 patients with recent AMI (4-16 days). The myocardium was divided into 16 segments and perfusion grade was measured visually with 4 point score from 0 to 3 (absent uptake to normal uptake). A perfusion defect with stress score 2 was considered moderate. A defect was considered severe if the stress score was 0 or 1 (absent uptake or severe perfusion decrease). Moderate defect on stress image were considered viable and segments with severe defect were considered viable if they showed improvement of 1 score or more on redistribution or reinjection images. We compared the results of viability assessment in stress-redistribution and stress-reinjection images. Results: On visual analysis, 344 of 688 segments (50%) had abnormal perfusion. Fifty two (15%) had moderate perfusion defects and 292 (85%) had severe perfusion defects on stress image. Of 292 severe stress defects, 53 were irreversible on redistribution and reversible on reinjection images, and 15 were reversible on redistribution and irreversible on reinjection images. Two hundred twenty four of 292 segments (76.7%) showed concordant results on stress-redistribution and stress-reinjection images. Therefore 24 hour reinjection image changed viability status from necrotic to viable in 53 segments of 292 severe stress defect (18%). However, myocardial viability was underestimated in only 5% (15/292) of severe defects by 24 hour reinjection. Conclusion: The 24 hour reinjection imaging is useful in the assessment of myocardial viability. It is more sensitive than 4 hour redistribution imaging. However, both redistribution and reinjection images are needed since they complement each other.

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A Case of Posterior Reversible Leukoencephalopathy Syndrome Following Poststreptococcal Glomerulonephritis (A군 사슬알균 감염 후 사구체신염 환아에서 발생한 가역적 후두부 뇌병증 증후군 1례)

  • Lee, Eun Kyoung;Kang, Jin Han;Ma, Sang Hyuk
    • Pediatric Infection and Vaccine
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    • v.22 no.2
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    • pp.113-116
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    • 2015
  • Posterior reversible leukoencephalopathy syndrome is a clinical radiographic syndrome of many causative factors. Sudden onset headache, vomiting, altered mental status, blurred vision and seizures are main symptoms shown in posterior reversible leukoencephalopathy syndrome. In addition, it typically shows radiological findings of edema in the white matter of posterior cerebrum, being in commonly bilateral but asymmetric. We report a case of poststreptococcal glomerulonephritis (PSGN) presenting as posterior reversible leukoencephalopathy syndrome. Immediate control of hypertension resulted in rapid and complete neurological recovery.

전기천공의 의학적 응용

  • Choe, Yun-Seok;Kim, Hong-Bae
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.02a
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    • pp.42-42
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    • 2010
  • 전기천공(electroporation)은 세포에 nanosecond-millisecond 정도의 폭을 가지는 전기 펄스를 0.4-1.5 kV/cm 의 세기로 인가하여 세포 막 표면에 나노미터 크기의 미세한 기공을 형성하는 기술로서, 1970년대 처음 발견된 이래 수십 년 동안 다양한 생명공학 분야에 적용되어 왔다. 적절한 전기 펄스 조건 하에서 생성된 세포 막 표면의 미세 기공은 일정 시간 후 다시 사라지는 가역적 특성을 가져 이를 가역적 전기천공(reversible electroporation)이라 부르며, 주로 친수성약물, 유전자, 효소, 항체 등의 물질을 세포 내로 주입시키는 데 사용한다. 반면 이보다 강한 전기 펄스 하에 생성된 미세 기공은 사라지지 않고 결국 세포의 생명력을 잃게 하는 기전으로 작용하며, 이를 비가역 전기천공(irreversible electroporation)이라 한다. 비가역 전기천공 기술은 가역적 전기천공 측면에서는 바람직하지 않은 현상으로 인식되기도 하였으나, 최근 들어 그 장점을 이용한 기술적 접근이 이루어지고 있다. 전기천공은 주로 식품산업에서 미생물을 죽이는 기술이나 세포의 체외(in vitro) 유전자 주입 기술에 응용되어 왔으나, 현재는 암을 치료하기 위한 의학적 기술로 큰 주목을 받으며 많은 연구들이 진행되고 있고, 일부 기술은 이미 상용화 단계에 와있다. 본 발표는 전기천공의 기술적 이론적 배경과 함께 다양한 의학적 응용 기술에 대한 정보를 제공하며, 국내외 기초 및 응용 연구 동향 파악을 통해 국내 저변 확대 및 추후 발전 전망에 대해 논의 할 것이다.

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The Time Responses of Spirometric Values in Response to Single Doses of Inhaled Salbutamol (기관지확장제 사용 후 시간에 따른 폐활량 측정치의 변화)

  • Park, Sun Hyo;Choi, Won-Il;Lee, Sang Won;Park, Hun Pyo;Seo, Yong Woo;Ku, Duk Hee;Lee, Mi Young;Lee, Choong Won;Jeon, Young June
    • Tuberculosis and Respiratory Diseases
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    • v.56 no.2
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    • pp.144-150
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    • 2004
  • Background : An assessment of the presence and the degree of reversibility of airflow obstruction is clinically important in patients with asthma or chronic obstructive pulmonary disease. However, the time responses of spirometric parameters in response to bronchodilator have not been well investigated. Methods: We studied 15 patients with asthma. Spirometric and mini-Wright peak expiratory flow measurements were performed at 15, 30, 45, and 60 minutes after using single dose($200{\mu}g$) of inhaled bronchodilator, salbutamol. Results : The mean values of forced expiratory volume in one second($FEV_1$) and forced vital capicaty(FVC) were significantly increased at 60 minutes after using bronchodilator in comparison to 15 minutes. And peak expiratory flow rate measured by either mass flow sensor or mini-Wright peak flow meter were significantly increased at 45 minutes after using bronchodilator in comparison to 15 minutes. Conclusions : To appropriate evaluation of the bronchodilator response in patients with reversible airflow limitation, it would be useful measuring either $FEV_1$ or PEF at the later time point 60 or 45 minutes in comparison to 15 minutes after using bronchodilator.

전기화학적 방법을 통한 spherically shaped CuO 합성 및 특성 연구

  • Cha, S;Nagaraju, Goli;Yu, J
    • Proceedings of the Korean Vacuum Society Conference
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    • 2016.02a
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    • pp.273.2-273.2
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    • 2016
  • 전기적인 장치를 필요로 하는 분야의 빠른 발전에 따라 그 기본이 되는 에너지 저장소자에 관한 연구가 많은 관심을 불러일으키고 있다. 특히, 다양한 에너지 저장 소자 중 기존의 배터리 보다 높은 에너지 밀도와 빠른 충전/방전 속도, 그리고 상대적으로 긴 수명을 가진 슈퍼커패시터에 관한 연구가 많이 이루어 지고 있다. 나노구조를 가진 슈도용량성 물질을 전극에 합성시키는 방법은 크게 두 가지로 나눌 수 있는데 수열합성법이나 전기화학적증착 방법 같이 인위적인 바인더를 사용하지 않고 직접 전극 표면에 합성시키는 방법이 있고, copecipitation이나 졸겔 방법으로 나노구조를 합성한 후 인위적인 바인더를 사용하여 전극 표면에 합성 시키는 방법이 있다. 본 연구에서는 짧은 시간에 물질을 합성시킬 수 있고 인위적인 바인더를 사용하지 않아 더욱 뛰어난 전기적인 특성을 보이는 전기화학적증착 방법을 이용하여 spherically shaped CuO를 전도성 직물에 직접 합성시켜 전기적인 특성을 연구하였다. 유연한 전도성 직물에 합성된 spherically shaped CuO 는 뛰어난 전기화학적 가역성, 상대적으로 높은 비정전용량, 그리고 많은 사이클 테스트에서도 높은 안정성을 보였다. 이처럼 손쉬운 방법으로 유연한 전도성 직물에 합성된 metal oxide 나노구조는 슈퍼커패시터 뿐만 아니라 염료감응형 태양전지, 다양한 종류의 센서 등 많은 분야에서 활용될 것으로 기대된다.

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Analysis of chaotic with lossless time-delayed chua's circuit (무손실 시간 지연을 갖는 Chua 회로에서의 카오스 해석)

  • 배영철;손영우;고윤석
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.22 no.2
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    • pp.318-324
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    • 1997
  • Chua's circuit is a simple electronic network which exhibits a variety of bifurcation and attractors. The circuit consists of two capacitors, a linear resistor, and a nonlinear resistor. In this papre we analyze a circuit obtained by replacing the parallel LC resonator in the Chua's circuit by lossless transmission line. By using the method of characteristics of this circuit we show that various periodic motions and chaotic motions can the attained according to parameter variations. From Chua's circuit with a lossless transmission line a variely of chaotic attractors which are similar to those of the normal Chua's circuit are observed.

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Study on the Urethane Restoration Filling Material and Adhesive for Stone Cultural Heritage (석조문화재 복원용 우레탄 메움제 및 접착제에 관한 연구)

  • Han, Won-Sik;Lee, Ho-Youn;Park, Gi-Jung;Hong, Tae-Kee;Wi, Koang-Chul
    • Journal of Conservation Science
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    • v.27 no.1
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    • pp.115-121
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    • 2011
  • A Urethane resin restoration material was made to be used in the restoration of stone cultural assets. The Urethane resin restoration material showed strong adhesive strength and tensile strength similar to epoxy recovery material, which had been mainly used for the recovery of stone cultural assets. The sealing property, anti-shrinking property and paint-ability of Urethane resin restoration material are also similar to existing epoxy system restoration materials. Especially, this Urethane resin restration material is expected to give permanence and continuous stability in the restoration of cultural assets made in stone by resolving the two big issues of existing epoxy recovery material, which are 'yellowing' and 'ir-reversibility'. This Urethane resin restration material had been directly applied as a filling material and adhesive and it was dissolved again. The Urethane resin, which had been used for the recovery, was able to be perfectly removed, which means that this Urethane resin recovery material has perfect reversibility. This Urethane resin restoration material also has enhanced convenience since user can adjust the working-life dependent on work environment. It is believed that this Urethane resin restoration material can also be used as a filling material or adhesive for other cultural assets made of ceramic or metal heritage, in addition to stone, since it has strong adhesive strength and tensile strength.

Effect of Heavy Metal Ions on the Oocyte Maturation of Frog, Rana dybowskii in vitro (중금속 이온이 산개구리 난자성숙에 미치는 영향에 관한 연구)

  • 고선근;이두표
    • Korean Journal of Environment and Ecology
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    • v.11 no.3
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    • pp.310-315
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    • 1997
  • In oreder to know the effect of the oocyte maturation with several heavy metal ions(Cd$^{2+}$, Hg$^{2+}$, Cu$^{2+}$, Pb$^{2+}$) on frog(Rana dybowskii) by FPH(Frog pituitary homogenate: 0.1 p.e./ml) in vitro, oocytes were cultured for 20 hours and exanimed the maturation rates with exposure of various comcentrations of those ions. The results showed that Cd$^{2+}$ at concentration of 0.1 ppm suppressed the maturation of the oocytes, while Hg$^{2+}$, Cu$^{2+}$ and Pb$^{2+}$ suppressed them significantly at 1 and 5 ppm respectively. To examine the reversibility of the inhibitory effects, the oocutes were exposed to the metal ions only for 3 hours and transferred to plain medium and cultured further for 17 hours. The oocytes were recovered from the toxic effect of the ions when they were exposed to 1 ppm of Cd$^{2+}$ for 3 hours and not available to 2.5 ppm. The effect of 2.5 ppm of Hg$^{2+}$, Cu$^{2+}$, Pb$^{2+}$ were also reversible and not available to 5 ppm for 3 hours exposure. From the abave results, it reveal that heavy metal ions in this study suppressed the maturation of oocytes at relatively low concentration. Therefore the oocyte culture system can be used as a useful tool to evaluate the toxicity of the pollutants in envirment.

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