• The Korean Journal of Applied Statistics
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• v.6 no.1
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• pp.125-143
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• 1993

The primary objective of the paper is to review the development of approximations of the null distribution of a scan statistic and to show how these approximations were improved. Let $X_1, \cdots, X_N$ be a sequence of independent uniform random variables on an interval (0, t]. A can statistic is defined to be the maximum number of observations in a subinterval of length t $\leq$ T, when we continuously (or discretely) move the subinterval from 0 to T. A scan statistic is used to test whether certain events occur in a cluster aganist a null hypothesis of the uniformity. It is difficult to calculate the exact null distribution of a scan statistic. Several authors have suggested approximations of the null distribution of a scan statistic since Naus(1966). We conceive that a scan statistic can be used for detecting a "hot region" is defined to be a region at which the frequencies of mutations are relatively high. A "hot region" may be regarded as a generalized version of a hot spot. We leave it for a further study the concrete formulation of deteciton a "hot region" in a mutational spectrum.uot; in a mutational spectrum.

• Journal of the Korean Data and Information Science Society
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• v.27 no.5
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• pp.1193-1201
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• 2016

In epidemiology or etiology, we are often interested in identifying areas of elevated risk, so called, hot spot or cluster. Many existing clustering methods only tend to a result if there exists any clustering pattern in study area. Recently, however, lots of newly introduced clustering methods can identify the location, size, and shape of clusters and test if the clusters are statistically significant as well. In this paper, one of most commonly used clustering methods, scan statistic, and its implementation SaTScan software, which is freely available, will be introduced. To exemplify the usage of SaTScan software, we used cancer data from the SEER program of National Cancer Institute of U.S.A.We aimed to help researchers and practitioners, who are interested in spatial cluster detection, using female lung cancer mortality data of the SEER program.

• Journal of Digital Convergence
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• v.20 no.3
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• pp.75-83
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• 2022

Korea, which has the highest pedestrian fatality rate among OECD countries, is making efforts to improve the safe walking environment by enacting laws focusing on pedestrian. Spatial clustering was conducted with scan statistics after examining the social network data related to traffic accidents for children and seniors. The word cloud was used to examine people's recognition Campaigns for children and literature survey for seniors were in main concern. Naedang and Yongsan are the regions with the highest relative risk of weak pedestrian for children and seniors. On the contrary, Bongmu and Beomeo are the lowest relative risk region. Naedang-dong and Yongsan-dong of Daegu Metropolitan City were identified as vulnerable areas for pedestrian safety due to the high risk of pedestrian accidents for children and the elderly. This means that the scan statistics are effective in searching for traffic accident risk areas.

• Proceedings of the Korean Statistical Society Conference
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• 2002.05a
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• pp.119-125
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• 2002

우리는 본 논문에서 디지털 영상에 대하여 Hash함수를 이용한 내용기반의 안전한 워터마킹 인증기술을 제시하려고 한다. 허가되지 않는 이미지의 내용변경을 막기 위해 안전한 워터마킹 시스템을 개발하기 위하여 비밀키를 가지고 있는 Hash 함수가 사용되었고, 각 블록의 워터마크신호는 Hash함수의 출력결과를 Seed로 사용하여 의사난수를 발생시킨 값에 따라 생성되어진다. 이미지 기술벡터들은 블록기반 에지 이미지로부터 측정되는데 이 값들은 해롭지 않는 조작 등에 대해서는 쉽게 변화하지 않지만 고의적인 내용변경 등의 조작에 대해서는 이들 값들이 바꾸어지는 성질을 갖고 있다. 워터마크신호의 삽입은 블록기반 스펙트럼 방법에 기초를 두고 있으며 워터마크신호의 크기는 인지성과 강인성이 조화를 이루도록 AC 부 밴드의 지그재그 스캔라인의 DCT 계수들의 지역적인 통계량에 따라 조정되어진다. 또한 저작권인증의 확인을 위한 경계 값의 선택은 통계학적으로 분석되어진다. 수치적인 실험의 결과는 제안된 기술이 강력한 저작권인증의 수행을 위해서 매우 효율적인 것을 보여주고 있다.

• The Journal of Korean Academy of Prosthodontics
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• v.58 no.4
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• pp.282-289
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• 2020

Purpose: The aim of this in vitro study was to evaluate the accuracy of three different intraoral scanners (IOSs) on digital impressions of different types of endocrown cavity preparations. Materials and methods: Two human mandibular molar teeth were prepared with different endocrown abutment designs: one with a buccal wall (Class 2) and the other without a buccal wall (Class 3). Both cavity designs were scanned using a reference desktop scanner (E3) and three different intraoral scanners: Trios3 (TRI group), Cerec Omnicam (CER group), and i500 (I5 group). The obtained Standard Tessellation Language (.stl) datasets were exported to metrology software. The precision was evaluated based on deviations among repeated scan models recorded by each IOS. The trueness was evaluated based on deviations between the reference data and repeated scans. For detecting interaction, data were statistically analyzed using a univariate analysis of variance (ANOVA) and for analyzing the comparison of the test groups data were analyzed by one-way ANOVA and post-hoc Tukey test at the significance level of .05. Results: The deviation values for both cavity designs in the I5 group were significantly lower than those in the other IOS groups in terms of trueness. For both cavity designs, the TRI group exhibited better precision than the other IOS groups. Conclusion: Different technologies of IOS device's and different endocrown prepration designs affected the accuracy of the digital scans.

• The Journal of Korean Academy of Prosthodontics
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• v.58 no.2
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• pp.86-94
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• 2020

Purpose: The purpose of this study is to compare the volume stability depending on the mixing methods and storage time for the conventional alginate and extended-pour alginate. Materials and methods: An arch-shaped metal model was fabricated, and one conventional alginate and two extended-pour alginates were used to take impressions using different mixing methods (hand and automatic). 120 impressions were taken (40 per each alginate) and stone models were made in accordance with the different storage times (immediate, 2 days, 5 days, and 6 days). The models were scanned with a 3D table scanner and dimensional change was measured by superimposing the scan data. Using SAS 9.4 (SAS Institute Inc., Cary, NC, USA), the general linear model and Tukey's post hoc test was conducted for statistical analysis (P<.001). Results: There was no statistically significant difference in the dimensional accuracy between two mixing methods, and the volume change was minimum when the stone was poured immediately in all groups. Dimensional accuracy showed a statistically significant difference between groups after 2 days of storage, and extended-pour alginate showed higher accuracy after 5 days of storage comparing to conventional one. Large amounts of volume change were showed at 2 - 5 days for conventional alginate and at 5 - 6 days for extended pour alginate. Conclusion: The mixing method of alginate does not affect volume stability. Although extended-pour alginate has better volume stability than conventional alginate for a long time, it is recommended to pour stone as soon as possible.

• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.1
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• pp.83-89
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• 2010

Purpose: The Wide Beam Reconstruction (WBR) algorithms that UltraSPECT, Ltd. (U.S) has provides solutions which improved image resolution by eliminating the effect of the line spread function by collimator and suppression of the noise. It controls the resolution and noise level automatically and yields unsurpassed image quality. The aim of this study is WBR of whole body bone scan in usefulness of clinical application. Materials and Methods: The standard line source and single photon emission computed tomography (SPECT) reconstructed spatial resolution measurements were performed on an INFINA (GE, Milwaukee, WI) gamma camera, equipped with low energy high resolution (LEHR) collimators. The total counts of line source measurements with 200 kcps and 300 kcps. The SPECT phantoms analyzed spatial resolution by the changing matrix size. Also a clinical evaluation study was performed with forty three patients, referred for bone scans. First group altered scan speed with 20 and 30 cm/min and dosage of 740 MBq (20 mCi) of $^{99m}Tc$-HDP administered but second group altered dosage of $^{99m}Tc$-HDP with 740 and 1,110 MBq (20 mCi and 30 mCi) in same scan speed. The acquired data was reconstructed using the typical clinical protocol in use and the WBR protocol. The patient's information was removed and a blind reading was done on each reconstruction method. For each reading, a questionnaire was completed in which the reader was asked to evaluate, on a scale of 1-5 point. Results: The result of planar WBR data improved resolution more than 10%. The Full-Width at Half-Maximum (FWHM) of WBR data improved about 16% (Standard: 8.45, WBR: 7.09). SPECT WBR data improved resolution more than about 50% and evaluate FWHM of WBR data (Standard: 3.52, WBR: 1.65). A clinical evaluation study, there was no statistically significant difference between the two method, which includes improvement of the bone to soft tissue ratio and the image resolution (first group p=0.07, second group p=0.458). Conclusion: The WBR method allows to shorten the acquisition time of bone scans while simultaneously providing improved image quality and to reduce the dosage of radiopharmaceuticals reducing radiation dose. Therefore, the WBR method can be applied to a wide range of clinical applications to provide clinical values as well as image quality.

• The Korean Journal of Nuclear Medicine Technology
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• v.21 no.1
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• pp.76-82
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• 2017

Purpose Whole body bone scan is one of the most frequently performed in nuclear medicine. Basically, both the anterior and posterior views are acquired simultaneously. Occasionally, it is difficult to distinguish the lesion by only the anterior view and the posterior view. In this case, accurate location of the lesion through SPECT / CT or additional static scan images are important. Therefore, in this study, various improvement activities have been carried out in order to enhance the work capacity of technologists. In this study, we investigate the effect of technologist training and standardized work process processes on bone scan error reduction. Materials and Methods Several systems have been introduced in sequence for the application of new processes. The first is the implementation of education and testing with physicians, the second is the classification of patients who are expected to undergo further scanning, introducing a pre-filtration system that allows technologists to check in advance, and finally, The communication system called NMQA is applied. From January, 2014 to December, 2016, we examined the whole body bone scan patients who visited the Department of Nuclear Medicine, Asan Medical Center, Seoul, Korea Results We investigated errors based on the Bone Scan NMQA sent from January 2014 to December 2016. The number of tests in which NMQA was transmitted over the entire bone scan during the survey period was calculated as a percentage. The annual output is 141 cases in 2014, 88 cases in 2015, and 86 cases in 2016. The rate of NMQA has decreased to 0.88% in 2014, 0.53% in 2015 and 0.45% in 2016. Conclusion The incidence of NMQA has decreased since 2014 when the new process was applied. However, we believe that it will be necessary to accumulate data continuously in the future because of insufficient data until statistically confirming its usefulness. This study confirmed the necessity of standardized work and education to improve the quality of Bone Scan image, and it is thought that update is needed for continuous research and interest in the future.

• Journal of Chest Surgery
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• v.30 no.9
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• pp.914-919
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• 1997

We analyzed the changes of pulmonary function after decortication i 33 patients with chronic empyema thoracis. In 11 patients of them, scintigraphic lung perfusion scan were performed. The results are as follows; 1, Forced expiratory volume in one second(FEVI) increased from 2.30 L/sec to 2.65 L/sec after decorticati on (p = 0.008) . 2. In patients under 20 years-old, PEV 1 increased significantly(p=0.001). 3. In patients who had tuberculosis empyema thoracis, FEVI increased significantly(p=0.008). The post-operative FEVI increased significantly 24 months later(p=0.013). 4. Te post-operative FEV1 increased significantly 24 months later(p=0013). 5. Perfusion and FEV1 of diseased lung changed from 21.5% to 26.9%(p=0.046) and 0.56 L/sec to 0.78 L/sec(p=0.071) after decortication respectively and perfusion of non-diseased lung changed 78.4% to 72.9% after decortication(p=0.042).

• Proceedings of the Korean Information Science Society Conference
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• 2007.06c
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• pp.153-158
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• 2007

사용자들의 특성에 맞게 개인화되고 세분화된 위치 기반 서비스를 제공하기 위해서는 방대한 이동 객체의 위치 이력 데이터 집합으로부터 유용한 패턴을 추출하여 의미 있는 지식을 탐사하기 위한 시공간 패턴 탐사가 필요하다. 현재까지 다양한 패턴 탐사 기법들이 제안되었으나 이동 패턴들 중 단순히 시공간 제약이 없는 빈발 패턴만을 추출하기 때문에 한정된 시간 범위와 제한적인 영역 범위 내에서의 빈발 패턴을 탐사하는 문제에는 적용하기 어렵다. 또한 패턴 탐사 수행 시 데이터베이스를 반복 스캔하여 탐사 수행시간이 많이 소요되는 문제를 포함하거나 메모리상에 탐사 대상인 후보 패턴 트리를 생성하는 방법을 통해 탐사 시간을 줄일 수는 있으나 이동 객체 수나 최소지지도 등에 따라 트리를 구성하고 유지하는데 드는 비용이 커질 수 있다. 따라서 이러한 문제를 해결하기 위한 효율적인 패턴 탐사 기법의 개발이 요구됨으로써 선행 작업으로 본 논문에서는 상세 수준의 객체 이력 데이터들의 시간 및 공간 속성을 의미 있는 시간영역과 공간영역 정보로 변환하는 시공간 데이터 일반화 방법을 제안한다. 제안된 방법은 공간 개념 계층에 대한 영역 정보들을 영역 Grid 해쉬 테이블(AGHT:Area Grid Hash Table)로 생성하여 공간 인덱스트리인 R*-Tree의 검색 방법을 이용해 이동 객체의 위치 속성을 2차원 공간영역으로 일반화하고, 시간 개념 계층을 생성하여 이동 객체의 시간적인 속성을 시간 영역으로 일반화함으로써 일반화된 데이터 집합을 형성하여 효율적인 이동 객체의 시간 패턴 마이닝을 유도할 수 있다.의 성능을 기대할 수 있을 것이다.onium sulfate첨가배지(添加培地)에서 가장 저조(低調)하였다. vitamin중(中)에서는 niacin과 thiamine첨가배지(添加培地)에서 근소(僅少)한 증가(增加)를 나타내었다.소시켜 항이뇨 및 Na 배설 감소를 초래하는 작용과, 둘째는 신경 경로를 통하지 않고, 아마도 humoral factor를 통하여 신세뇨관에서 Na 재흡수를 억제하는 작용이 복합적으로 나타내는 것을 알 수 있었다.으로 초래되는 복합적인 기전으로 추정되었다., 소형과와 기형과는 S-3에서 많이 나왔다. 이상 연구결과에서 입도분포가 1.2-5mm인 것이 바람직한 것으로 나타났다.omopolysaccharides로 확인되었다. EPS 생성량이 가장 좋은 Leu. kimchii GJ2의 평균 분자량은 360,606 Da이었으며, 나머지 두 균주에 대해서는 생성 EPS 형태와 점도의 차이로 미루어 보아 생성 EPS의 분자구조와 분자량이 서로 다른 것으로 판단하였다.TEX>개로 통계학적으로 유의한 차이가 없었다. Heat shock protein-70 (HSP70)과 neuronal nitric oxide synthase (nNOS)에 대한 면역조직화학검사에서 실험군 Cs2군의 신경세포가 대조군 12군에 비해 HSP70과 nNOS의 과발현을 보였으며, 이는 통계학적으로 유의한 차이를 보였다(p<0.05). nNOS와 HSP70의 발현은 강한 연관성을 보였고(상관계수 0.91, p=0.000), nNOS를 발현하는 세포가 동시에 HSP70도 발현함을 확인할 수 있었다. 결론: 우리는