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Comparison of 99mTc-Tin colloid colloid and 99mTc-DISIDA Hepatoscintigraphy in Miniature Pigs (미니돼지에서 99mTc-Tin colloid와 99mTc-DISIDA를 사용한 간신티그라피의 비교 연구)

  • Shim, Kyung-Mi;Kim, Se-Eun;Lee, Won-Guk;Koong, Sung-Soo;Bae, Chun-Sik;Lee, Jae-Yeong;Choi, Seok-Hwa;Han, Ho-Jae;Kang, Seong-Soo;Park, Soo-Hyun
    • Journal of Life Science
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    • v.16 no.6
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    • pp.1060-1065
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    • 2006
  • Non-invasive evaluation of liver function in animal models remains a challenge. Hepatoscintigraphy provides information about changes in liver size and shape, and enables to understand general liver function. Futhermore it is readily used to diagnosis complications of liver transplantation like hepatitis, rejections and biliary complications. In this study, we investigated the usefulness of evaluating the liver function in miniature pigs with $^{99m}Tc-Tin$ colloid and $^{99m}Tc-DISIDA$ which are the most commonly used radiopharmaceuticals in human medicine. In result, $^{99m}Tc-Tin$ colloid was uptaked in lung, liver, gastric wall and kidney in miniature pigs. And $^{99m}Tc-DISIDA$ showed continuous uptake images of heart, lung, liver, gallbladder and duodenum, and it was similar to human's. Therefore we could conclude $^{99m}Tc-Tin$ colloid would not be suitable for evaluating hepatic function because of it's nonspecific affinity, however $^{99m}Tc-DISIDA$ scintigraphy would be an effective method for detecting hepatobiliary function in miniature pigs.

Quality Characteristics of Frozen Doraji (Platycodon grandiflorum) according to Various Blanching Treatment Conditions (블랜칭 처리 조건에 따른 동결 도라지의 품질 특성)

  • Lee, Young-Joo;Lee, Hye-Ok;Kim, Ji-Young;Kwon, Ki-Hyun;Cha, Hwan-Soo;Kim, Byeong-Sam
    • Food Science and Preservation
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    • v.18 no.5
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    • pp.661-668
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    • 2011
  • This study was conducted to devise appropriate blanching-process conditions as a means to convert Doraji, which is widely used in Korean food due to its unique fragrance and flavor, into frozen food materials for various uses. For the Hunter L values representing the brightness transformation among the surface color and gloss changes that were observed in Doraji before and after freezing, and after Doraji went through a blanching process, the specimen that went through a blanching process at $80^{\circ}C$ showed a significantly higher value compared to another specimen processed at a higher temperature, and the first specimen's value also rose after freezing. Meanwhile, for the hardness values, they declined more as the blanching temperature became higher and as the processing time became longer. For the number of total counts and the number of coliform groups, the number of total counts at $3.75{\times}10^5$ and $1.25{\times}10^5$ cfu/g before the blanching process was reduced into the approximately 2-3 log scale, and no coliform group was detected after the blanching process. As for the peroxidase activity, its activation was decreased by the blanching process, and more than 89% of the peroxidase became inactivated in all the specimens that went through the blanching process. The sensory characteristics of the frozen-thawed Doraji by test group showed the radish leaves blanched at $90^{\circ}C$ for 1 min to be the most highly evaluated in terms of the overall preference level (p<0.05).

Assessment Research Comparing the Environmental Value of Taebaeksan·NakSan·Kyeongpo Provincial Parks of Kangwon-do (태백산, 낙산, 경포도립공원의 환경가치비교 평가연구)

  • Kang, Kee-Rae;Kim, Dong-Pil;Cho, Woo;Baek, Jae-Bong
    • Korean Journal of Environment and Ecology
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    • v.30 no.2
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    • pp.253-260
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    • 2016
  • This research aimed to quantitatively measure the environmental values of Taebaeksan, Naksan, and Gyeongpo provincial parks located in Gangwon-do. The research was based on the CVM technique which estimates the economic values for all kinds of ecosystem. Also, the estimated value of environment goods can suggest the magnitude of additional utility other than the cost people pay when they visit the provincial parks. Such result can be used as basic data in addition to information on natural ecology or cultural landscape to decide whether the park should be promoted as a national park. The questionnaires-collected from Taebaeksan(180 copies), Naksan(179 copies), and Gyeongpo(180 copies) provincial parks were used to measure the environmental value of each provincial park. Variables that affect the response of 'yes(Y)' or 'no(N)' to the cost suggestion for the economic valuation of environment are estimated under the catagories of environment conservation status (env.), degree of park management (manage.), environmental conservation effort, education (edu.), and income (inc.) of the respondents (execu.), pertaining to the 3 provincial parks in Gangwon-do. The value of natural environment to 1 visitor to the 3 Gangwon provincial parks was estimated by the Logit method that Hanemann proposed using the average of inserted variables. The results showed that the additional environmental value that 1 visitor can gain is 44,060 won for Taebaeksan Provincial Park, 41,191 won for Naksan, and 41,844 won for the Gyeongpo Provincial Park. Taebaeksan Provincial Park's environmental value is estimated at the highest as the respondents judge that its natural environment is well preserved and the facilities are managed well.

Present Status of Non-Native Amphibians and Reptiles Traded in Korean Online Pet Shop (한국 온라인 펫샵에서 거래되는 외래 양서파충류 현황)

  • Koo, Kyo Soung;Park, Hye Rin;Choi, Jae Hyeok;Sung, Ha Cheol
    • Korean Journal of Environment and Ecology
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    • v.34 no.2
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    • pp.106-114
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    • 2020
  • The development of transportation and the expansion of the pet market has become the main causes of the increase in the cross-border migration of non-native species. Moreover, recent sales over the Internet were a factor that has promoted pet trades. While the import of non-native species has been steadily increasing in the Republic of Korea, it is not clear how these imported species are traded and how large the trade is. Considering that most of the non-native species found in the wild are the results of release by humans understanding the present situation of pet trades can identify potential non-native species that can enter the wild. This study surveyed the number of species, frequency, and prices of non-native amphibians and reptiles sold in 25 online pet shops from January 22 to February 10, 2019. The results of the survey showed that a total of 677 species of non-native amphibians and reptiles were sold, and the Squamata group accounted for the largest part of them at 65.4% (443 species). The number of non-native amphibians and reptiles sold in online pet shops in 2019 was 2.1 times larger than the 325 species officially imported in 2015. The non-native amphibians and reptiles sold in most pet shops were Litoria caerulea (21 shops) and Correlophus ciliatus (24 shops). The lowest price for non-native amphibians and reptiles was 3,000 won, and the highest price was 100 million won for Rhacodactylus leachianus of Squamata. Among the non-native amphibians and reptiles sold in online pet shops, 11 species were found in the wild and were sold at relatively low prices. We confirmed that Mauremys reevesii, an endangered species class II and natural monument no. 453, and American bullfrogs (albino), an ecosystem disturbing species, were being sold in online pet shops. Moreover, 21.6% of the 677 non-native amphibians and reptiles sold in online pet shops were species designated as CITES. The results of this study can be the important reference data for understanding the status of non-native amphibians and reptiles that are imported and sold in Korea and evaluating and predicting the potential for them to enter the wild.

Research on the current conditions of cultural heritage management in North Korea - an example of the management of provincial sites - (북한의 문화유산 관리 현황 연구 - 지방의 유적 관리 사례를 중심으로 -)

  • Kim, Hyunwoo;Yi, Seonbok
    • Korean Journal of Heritage: History & Science
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    • v.52 no.4
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    • pp.4-17
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    • 2019
  • Both as a means of improving North-South relations, as well as a necessary component for carrying out research on the past of the Korean peninsula, interest in North Korean cultural resources has been growing in South Korean society. As a result, studies have begun to look beyond North Korean cultural resources themselves and attempt to determine how cultural resources are managed in North Korea. Such studies have tended to investigate laws related to the management of cultural heritage in North Korea, but information gleaned from laws alone is limited. To provide a more complete picture, research must also investigate how cultural resource management laws are applied and enforced and also take into consideration aspects of cultural resource management that are not directed or regulated by law. In this study, we refer to the current National Cultural Resources Protection Laws in order to investigate systems of cultural resource management in North Korea. Furthermore, we conducted interviews with a former North Korean national who had until recently worked as a director of historical sites in North Korea. Through comparisons of information relating to organization, labor power, responsibilities, budget, and other factors of cultural resource management gained through the interviews and the 'National Cultural Resources Protection Laws,' we hoped to gain a fuller understanding of the reality of cultural resource management in North Korea. As a result, we were able to gain a better understanding of the organization and tasks related to cultural resource management and, at the same time, clarify some of the provisions that were unclear in the laws. Throughout the process, we were also able to determine that the management of cultural resources in North Korea is currently inadequate. However, because this study focuses on a specific region and is limited only to historical sites, it is difficult to generalize our findings to the entirety of cultural resource management in North Korea. In order to gain an objective and more accurate understanding of the current state of cultural resource management in North Korea, information must be collected at many levels to be synthesized and compared.

Selection of RAPD marker to discriminate the bolting-resistant varieties and commercial dried medicinal materials of Angelica species (당귀 내추대성 품종 및 건재약재 판별을 위한 RAPD marker 선발)

  • Bang, Kyong-Hwan;Yu, Hong-Seob;Koo, Dal-Hoe;Cho, Joon-Hyeong;Park, Hee-Woon;Seong, Nak-Sul;Park, Sang-Il;Kim, Hong-Sig
    • Korean Journal of Medicinal Crop Science
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    • v.10 no.1
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    • pp.46-50
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    • 2002
  • In DNA level, genetic study of Angelica species was firstly conducted to discriminate the bolting-resistant or low bolting variety, so called as Manchu, from other Korea collected lines and also this technuque was applied to identify the origin of commercial dried materials obtained from current oriental medicinal market. By RAPD analysis with 72 primers including sixty of 10-mers and twelve of 20-mers, respectively, three primers, which were related to the bolting resistant traits of Angelica gigas, were identified. Comparing the RAPD bands, URP04 primer showed the 1.7 kb specific band, which seemed to be related to delaying bolting traits, since it was observed only in Jinbu elite lines but not in others. On the other hand, since 1.2 kb band amplified by OPD11 was observed in other collected lines but not in Manchu var. and Jinbu line, this primer also could be considered as a selection marker for identifying bolting resistant or delaying bolting traits. In the same manner, since OPP09 did not show 1 kb major band but produced 0.8 kb and 1.2 kb bands in Manchu var., these three bands amplified by the primer could be considered one of the important key specifying Manchu var. related with the trait of Angelica gigas. OPC02 primer showed the same band patterns in all Korean collected lines, but not in other foreign introduced lines, such as A. sinensis from China, and A. acutiloba from Japan. Since these four RAPD primers, OPD11, OPP09, URP04, and OPC02 showed the specific polymorphisms in Angelica species, thus, these were useful to discriminate the three Angelica species, A. gigas, A. sinensis, and A. acutiloba.

Determinants of Mobile Application Use: A Study Focused on the Correlation between Application Categories (모바일 앱 사용에 영향을 미치는 요인에 관한 연구: 앱 카테고리 간 상관관계를 중심으로)

  • Park, Sangkyu;Lee, Dongwon
    • Journal of Intelligence and Information Systems
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    • v.22 no.4
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    • pp.157-176
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    • 2016
  • For a long time, mobile phone had a sole function of communication. Recently however, abrupt innovations in technology allowed extension of the sphere in mobile phone activities. Development of technology enabled realization of almost computer-like environment even on a very small device. Such advancement yielded several forms of new high-tech devices such as smartphone and tablet PC, which quickly proliferated. Simultaneously with the diffusion of the mobile devices, mobile applications for those devices also prospered and soon became deeply penetrated in consumers' daily lives. Numerous mobile applications have been released in app stores yielding trillions of cumulative downloads. However, a big majority of the applications are disregarded from consumers. Even after the applications are purchased, they do not survive long in consumers' mobile devices and are soon abandoned. Nevertheless, it is imperative for both app developers and app-store operators to understand consumer behaviors and to develop marketing strategies aiming to make sustainable business by first increasing sales of mobile applications and by also designing surviving strategy for applications. Therefore, this research analyzes consumers' mobile application usage behavior in a frame of substitution/supplementary of application categories and several explanatory variables. Considering that consumers of mobile devices use multiple apps simultaneously, this research adopts multivariate probit models to explain mobile application usage behavior and to derive correlation between categories of applications for observing substitution/supplementary of application use. The research adopts several explanatory variables including sociodemographic data, user experiences of purchased applications that reflect future purchasing behavior of paid applications as well as consumer attitudes toward marketing efforts, variables representing consumer attitudes toward rating of the app and those representing consumer attitudes toward app-store promotion efforts (i.e., top developer badge and editor's choice badge). Results of this study can be explained in hedonic and utilitarian framework. Consumers who use hedonic applications, such as those of game and entertainment-related, are of young age with low education level. However, consumers who are old and have received higher education level prefer utilitarian application category such as life, information etc. There are disputable arguments over whether the users of SNS are hedonic or utilitarian. In our results, consumers who are younger and those with higher education level prefer using SNS category applications, which is in a middle of utilitarian and hedonic results. Also, applications that are directly related to tangible assets, such as banking, stock and mobile shopping, are only negatively related to experience of purchasing of paid app, meaning that consumers who put weights on tangible assets do not prefer buying paid application. Regarding categories, most correlations among categories are significantly positive. This is because someone who spend more time on mobile devices tends to use more applications. Game and entertainment category shows significant and positive correlation; however, there exists significantly negative correlation between game and information, as well as game and e-commerce categories of applications. Meanwhile, categories of game and SNS as well as game and finance have shown no significant correlations. This result clearly shows that mobile application usage behavior is quite clearly distinguishable - that the purpose of using mobile devices are polarized into utilitarian and hedonic purpose. This research proves several arguments that can only be explained by second-hand real data, not by survey data, and offers behavioral explanations of mobile application usage in consumers' perspectives. This research also shows substitution/supplementary patterns of consumer application usage, which then explain consumers' mobile application usage behaviors. However, this research has limitations in some points. Classification of categories itself is disputable, for classification is diverged among several studies. Therefore, there is a possibility of change in results depending on the classification. Lastly, although the data are collected in an individual application level, we reduce its observation into an individual level. Further research will be done to resolve these limitations.

Comparison of Digital Mammography and Digital Breast Tomosynthesis (디지털 유방촬영기기와 3차원 디지털 유방단층영상합성기기의 비교연구)

  • Kim, Ye-Seul;Park, Hye-Suk;Choi, Jae-Gu;Choi, Young-Wook;Park, Jun-Ho;Lee, Jae-Jun;Kwak, Su-Bin;Kim, Eun-Hye;Kim, Ju-Yeon;Jung, Hyun-Jung;Lee, Haeng-Hwa;Bae, Gyu-Won;Lee, Mi-Young;Kim, Hee-Joung
    • Progress in Medical Physics
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    • v.23 no.4
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    • pp.261-268
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    • 2012
  • Breast cancer is the second leading cause of women cancer death in Korea. The key for reducing disease mortality is early detection. Although digital mammography (DM) has been credited as one of the major reasons for the early detection to decrease in breast cancer mortality observed in the last 20 years, DM is far from perfect for several limitations. Digital breast tomosynthesis (DBT) is expected to overcome some inherent limitations of conventional mammography caused by overlapping of normal tissue and pathological tissue during the standard 2D projections for the improved lesion margin visibility and early breast cancer detection. In this study, we compared a DM system and DBT system acquired with different thickness of breast phantom. We acquired breast phantom data with same average glandular dose (AGD) from 1 mGy to 4 mGy under same experimental condition. The contrast, micro-calcification measurement accuracy and observer study were conducted with breast phantom images. As a result, the higher accuracy of lesion detection with DBT system compared to DM system was demonstrated in this study. Furthermore, the pain of patients caused by severe compression can be reduced with DBT system. In conclusion, the results indicated that DBT system play an important role in breast cancer detection.

A Microgravity for Mapping and Monitoring the Subsurface Cavities (지하 공동의 탐지와 모니터링을 위한 고정밀 중력탐사)

  • Park, Yeong-Sue;Rim, Hyoung-Rae;Lim, Mu-Taek;Koo, Sung-Bon
    • Geophysics and Geophysical Exploration
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    • v.10 no.4
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    • pp.383-392
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    • 2007
  • Karstic features and mining-related cavities not only lead to severe restrictions in land utilizations, but also constitute serious concern about geohazard and groundwater contamination. A microgravity survey was applied for detecting, mapping and monitoring karstic cavities in the test site at Muan prepared by KIGAM. The gravity data were collected using an AutoGrav CG-3 gravimeter at about 800 stations by 5 m interval along paddy paths. The density distribution beneath the profiles was drawn by two dimensional inversion based on the minimum support stabilizing functional, which generated better focused images of density discontinuities. We also imaged three dimensional density distribution by growing body inversion with solution from Euler deconvolution as a priori information. The density image showed that the cavities were dissolved, enlarged and connected into a cavity network system, which was supported by drill hole logs. A time-lapse microgravity was executed on the road in the test site for monitoring the change of the subsurface density distribution before and after grouting. The data were adjusted for reducing the effects due to the different condition of each survey, and inverted to density distributions. They show the change of density structure during the lapsed time, which implies the effects of grouting. This case history at the Muan test site showed that the microgravity with accuracy and precision of ${\mu}Gal$ is an effective and practical tool for detecting, mapping and monitoring the subsurface cavities.

The Estimation of Gross Primary Productivity over North Korea Using MODIS FPAR and WRF Meteorological Data (MODIS 광합성유효복사흡수율과 WRF 기상자료를 이용한 북한지역의 총일차생산성 추정)

  • Do, Na-Young;Kang, Sin-Kyu;Myeong, Soo-Jeong;Chun, Tae-Hun;Lee, Ji-Hye;Lee, Chong-Bum
    • Korean Journal of Remote Sensing
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    • v.28 no.2
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    • pp.215-226
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    • 2012
  • NASA MODIS GPP provides a useful tool to monitor global terrestrial vegetation productivity. Two major problems of NASA GPP in regional applications are coarse spatial resolution ($1.25^{\circ}{\times}1^{\circ}$) of DAO meteorological data and cloud contamination of MODIS FPAR product. In this study, we improved the NASA GPP by using enhanced input data of high spatial resolution (3 km${\times}$3 km) WRF meteorological data and cloud-corrected FPAR over the North Korea. The improved GPP was utilized to investigate characteristics of GPP interannual variation and spatial patterns from 2000 to 2008. The GPP varied from 645 to 863 $gC\;m^{-2}\;y^{-1}$ in 2000 and 2008, respectively. Mixed forest showed the highest GPP (1,076 $gC\;m^{-2}\;y^{-1}$). Compared to NASA GPP (790 $gC\;m^{-2}\;y^{-1}$);FPAR enhancement increased GPP (861) but utilization of WRF data decreased GPP (710). Enhancements of both FPAR and meteorological input resulted in GPP increase (809) and the improvement was the greatest for mixed forest regions (+10.2%). The improved GPP showed better spatial heterogeneity reflecting local topography due to high resolution WRF data. It is remarkable that the improved and NASA GPPs showed distinctly different interannual variations with each other. Our study indicates improvement of NASA GPP by enhancing input variables is necessary to monitor region-scale terrestrial vegetation productivity.