• Title/Summary/Keyword: 생체지표

Search Result 341, Processing Time 0.027 seconds

The Measurements of Biomass Burning Aerosols from GLI Data (GLI 자료를 이용한 생체 소각 에어러솔 측정에 대한 연구)

  • Lee Hyun Jin;Fukushima Hajime;Ha Kyung-Ja;Kim Jae Hwan
    • Korean Journal of Remote Sensing
    • /
    • v.21 no.4
    • /
    • pp.273-285
    • /
    • 2005
  • This study has investigated the suitable wavelength for detecting biomass burning aerosols. We have performed the analysis of the wavelength at 380nm in near-UV, 400nm, 412nm, 460nm, and 490nm in visible, and 2100nm in shortwave infrared regions from the Global Imager measurements. It is well known that the UV bands have the advantage of the aerosols retrieval due to the low surface reflectance and a weak effect of Bidirectional Reflectivity Distribution Function. However, the pure surface reflectances of shortwave visible bands, except 412nm, are as low as that of 380nm in near-UV over northeast Asia. In order to detect the aerosol signal, we have retrieved the aerosol reflectance as a function of wavelength based on the surface reflectivity contrast method for the period of May 2003. It is interesting that the retrieved aerosol reflectance with 460nm is slightly more sensitive than that with 380nm. Additionally, we have applied the TOMS aerosol index method to determine the best pair for biomass burning aerosols and found that the pair of 380 and 460nm results in the best signal for retrieving aerosols.

Effects of Thermal and Salinity Stress on Expression of FK506BP in the Red Seabream (Pagrus major) (참돔(Pagrus major)에서 온도 및 염분 스트레스가 FK506BP 발현에 미치는 영향)

  • Min, Byung Hwa;Myeong, Jeong-In;Kang, Han Seung
    • Journal of Marine Life Science
    • /
    • v.2 no.1
    • /
    • pp.34-38
    • /
    • 2017
  • FK506BP (FK506 binding protein 12) is a small peptide with a single FK506BP domain. It is involved in suppression of immune response, oxidative stress and inflammation. The purpose of this study was to investigate the gene expression of FK506BP in red seabream (Pagrus major) exposure to low water temperature (8℃, 33 psu) and low salinity (20℃, 10 psu). Results showed that, the expression of FK506BP was significantly increased in the experiment groups, such as low water temperature (8℃, 33 psu), and low salinity (20℃, 10 psu). These results suggest that FK506BP was played roles in biomarker gene on the environmental stress such as water temperature and salinity.

Effects of Environmental Factors Such as Temperature and Salinity on Expression of Interleukin-1 Receptor Accessory Protein in the Red Seabream (Pagrus major) (온도 및 염분 등의 환경요인이 참돔(Pagrus major)의 Interleukin-1 Receptor Accessory Protein 발현에 미치는 영향)

  • Kang, Han Seung;Min, Byung Hwa
    • Journal of Marine Life Science
    • /
    • v.2 no.2
    • /
    • pp.70-74
    • /
    • 2017
  • Interleukin-1 (IL-1) is one of the proinflammatory cytokines, after IL-1 binds to IL-1RI, IL-1RacP (interleukin-1 receptor accessory protein) joins with IL-1/IL-1RI to form a complex, and leading to cell activation. IL-1RAcP is involved in immune response, stress and apoptosis. The purpose of this study was to investigate the gene expression of IL-1RAcP in red seabream (Pagrus major) exposure to low water temperature (8℃, 33 psu) and low salinity (20℃, 10 psu). Results showed that, the expression of IL-1RAcP was significantly increased in the experiment groups, such as low water temperature (8℃, 33 psu), and low salinity (20℃, 10 psu). These results suggest that IL-1RAcP was played roles in biomarker gene on the environmental stress such as low water temperature and low salinity.

Evaluation of Arousal Level to Prevent Drowsy Driving by Fuzzy Inference (졸음운전 방지를 위한 fuzzy 추론에 의한 각성도의 평가)

  • Kim, Y. H.;Ko, H. W.;Lyou, J.
    • Journal of Biomedical Engineering Research
    • /
    • v.18 no.4
    • /
    • pp.491-498
    • /
    • 1997
  • This paper describes the arousal measurement and control system using fuzzy logic to prevent drowsy driving. Sugeno's method was used for fuzzy inference in this study. Arousal evaluation and control criteria were modified from result of Nz-IRI analysis depending on arousal sate. Membership function and rule base of fuzzy inference were determined from the modified arousal level criteria When lRl (Inter-SIR Interval) was shorter than 60sec, outputs of both methods were changed from small to big, but output of three step warning method was same level until the next warning range. Since output of fuzzy inference tracked well the change of subject's arousal level, problems of three step warning method could be overcome by fuzzy inference method Furthermore, the output of the fuzzy inference was highly correlated with Nz(r = 0.99). Therefore, the fuzzy inference method for evaluation and the control of arousal will be more effective at real driving situation than three step warning method.

  • PDF

A Study on Measurements of Optical Absorption Coefficients of Biological tissue (생체조직의 광학적 흡수계수 측정에 관한 연구)

  • 임현수;김남중
    • Journal of Biomedical Engineering Research
    • /
    • v.20 no.2
    • /
    • pp.213-220
    • /
    • 1999
  • In this study, we measured the absorption coefficient of the tissues of mouse (brain, heart, liver, muscle and tumor) and human brain (normal and tumor) in the wavelength between 500nm~900nm. The optical coefficient is a representative of the characteristics of the materials. So, we can characterize the biological tissue with the optical coefficients. Using the spectrograph monometer and PDA(Photo Diode Array), we experimented with quick-frozen sectioned specimens. Because the optical coefficient is concerned with the conformation and biochemical component of the biological tissue, we experimented as the wavelength between 500nm~900nm on the normal and tumor samples of the animal and human. For the mouse, there are distinctive differences of the absorption coefficients between normal tissues and tumor. The absorption coefficient of the normal tissue varies 0.1~0.2cm$^{-1}$ with wavelength. But, the absorption coefficient of the brain tumor is changed round about 0.4~0.5cm$^{-1}$ as the wavelength. The absorption coefficients we measured can be a useful implement to detect diseases.

  • PDF

녹용 물추출액이 흰쥐혈액중의 급성기 반응 단백질에 미치는 영향

  • 한용남;김경옥;황금희
    • Proceedings of the Korean Society of Applied Pharmacology
    • /
    • 1994.04a
    • /
    • pp.238-238
    • /
    • 1994
  • 녹용의 알려진 약리작용 중에서 녹용의 상용량 투여에 의해 나타나는 것은 강장작용과 창상치유작용이므로 이러한 작용이 진정한 녹용의 효능으로 간주될 수 있으나 이러한 작용을 생물활성 검색법으로 활용하여 녹용의 유효성분을 검색하기에는 재현성과 간편성이라는 면에서 어려운 점이 없지 않다. 녹용의 효능이 생체의 질소평형이 음의 방향으로 진행되었을 때 이를 정상 수준으로 복귀시키는 생물활성에 기인할 것이라는 가정하에서, 실험적으로 생체내 질소편형을 음의 방향으로 전환시킬 수 있는 급성기 반응 (acute-phase responce)을 야기시킨 다음 녹용의 효과를 연구하였다. 흰쥐의 급성기 반응물질 (acute-phase reactants, APR) 중에 서 positive ARP인 ceruloplasmin, $\alpha$-cysteine pretense inhibitor(= T-kininogen)는 비색정량법으로 간편하게 측정될수 있음에 착안하여 이 단백질을 지표로 삼아 turpentine oil로 급성 염증을 유발시킨 전후에 녹용 물추출액의 효과를 측정하였다. 그 결과 녹용의 상용량에서 괴소 4일 이상 경구투여한 흰쥐에서 급성 염증유발 후 4일에서 ceruloplasmin 의 혈중농도가 현저히 감소함을 알수 있었다. 급성 염증 유발후 녹용의 경구투여한 실험에서는 적어도 녹용 상용량의 3배 이상을 투여하여야 만 ceruloplasmin 혈중 농도를 감소시킬 수 있었다. 본 연구에서 수립된 생물활성을 이용하여 녹용의 유효 성분을 단리할 계획이다.

  • PDF

Gene Expression Profiling in the Nematode Caenorhabditis elegans, as a Potential Biomarker for Soil Ecotoxicology (잠재적 생체지표 발굴을 위한 토양선충 Caenorhabditis elegans에서의 유전자 발현 연구)

  • Roh, Ji-Yeon;Choi, Jin-Hee
    • Environmental Analysis Health and Toxicology
    • /
    • v.25 no.1
    • /
    • pp.1-10
    • /
    • 2010
  • Monitoring toxicity levels in specific biological compartments is necessary to evaluate the ecotoxicological risk associated with soil environmental pollution. Gene expression, as potential biomarker, is increasingly used as rapid early warning systems in environmental monitoring and ecological risk assessment procedures. Various representative species are currently used for the purpose of assessing soil toxicity, however, investigations on toxicological assessments using endpoint based on gene-level have been limited. In this review, we will present the current trends in organisms and endpoints used in soil toxicity study and report gene expression related to toxicity using soil organism, and C. elegans as promising organisms for this approach.

HMM-Based Human Gait Recognition (HMM을 이용한 보행자 인식)

  • Sin Bong-Kee;Suk Heung-Il
    • Journal of KIISE:Software and Applications
    • /
    • v.33 no.5
    • /
    • pp.499-507
    • /
    • 2006
  • Recently human gait has been considered as a useful biometric supporting high performance human identification systems. This paper proposes a view-based pedestrian identification method using the dynamic silhouettes of a human body modeled with the Hidden Markov Model(HMM). Two types of gait models have been developed both with an endless cycle architecture: one is a discrete HMM method using a self-organizing map-based VQ codebook and the other is a continuous HMM method using feature vectors transformed into a PCA space. Experimental results showed a consistent performance trend over a range of model parameters and the recognition rate up to 88.1%. Compared with other methods, the proposed models and techniques are believed to have a sufficient potential for a successful application to gait recognition.

Correlations between Cell Abundance, Bio-volume and Chlorophyll $a$ Concentration of Phytoplankton Communities in Coastal Waters of Incheon, Tongyeong and Ulsan of Korea (식물플랑크톤 군집의 개체수, 생체량, chlorophyll $a$의 상관성; 인천, 통영, 울산 해역을 중심으로)

  • Joo, Hyoung-Min;Lee, Jin-Hwan;Jung, Seung-Won
    • Korean Journal of Environmental Biology
    • /
    • v.29 no.4
    • /
    • pp.312-320
    • /
    • 2011
  • In order to estimate a better methodological factor to understand phytoplankton ecology between abundance and bio-volume of phytoplankton, each 1,160 phytoplankton data, including abundance, classification and chlorophyll $a$ concentration were collected in Korean coastal waters of Incheon (Yellow sea), Tongyeong (South sea), and Ulsan (East sea). Based on these data, phytoplankton bio-volume can be calculated through a geometric model. The correlation coefficient between abundance and chlorophyll $a$ concentration was higher than the coefficient between biovolume and chlorophyll $a$ concentration, because a small size phytoplankton has relatively dense chlorophyll contents compared with the proportion of chlorophyll in a large size phytoplankton. Thus, the interpretation using abundance to understand phytoplankton ecology in Korean coastal waters may be more effective than that using bio-volume.

Differences of central and autonomic responses between olfactory stimuli with Lavenar and Jasmin in human (Lavendar와 Jasmin으로 유발된 후각 강성에 대한 중추 및 자율신경계 반응)

  • 백은주;이윤영;하태환;임재중;이배환
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
    • /
    • 1998.11a
    • /
    • pp.158-162
    • /
    • 1998
  • 향에 의해 유발되는 감성에 대한 중추신경계 및 자율신경계의 반응의 변화를 측정하기 위해 안정시키는 향과 각성시키는 향을 사용하여 주관적 평가와 동시에 시행하였다. 안정시키는 향으로 1% Lavendar 향을 사용하였고, 각성시키는 향으로 0.8% Jasmin 향을 사용하였으며, 안정상태를 향자극 전후에 측정하여 대조군으로 사용하였다. 중추신경계의 지표로 뇌파측정을 하였고 뇌파의 전극은 international 10-20 system에서 4 채널을 사용하였으며, 자율신경계의 지표로는 심전도, heart rate, 피부저항, 피부온도를 기록하였다. 뇌파의 분석은 Fast Fourier Transform analysis의 power spectra로 하였고, 그 frequency bands는 theta(4-8Hz), alpha(8-l3Hz), beta(14-30Hz)로 하였다 또한 심전도를 이용하여 심전도 상의 연속적인 R-R peak간 시간간격을 시계열 데이터로 재구성한 Heart rate variability 분석도 하였다. HRV 분석을 보다 정확히 할 수 있도록 호흡이 심전도에 미치는 영향을 제거하기 위하여 호흡을 분당 20회로 일정하게 하였다 생체신호 측정과 동시에 실시한 주관적 검사에서 lavendar 향은 친숙하게, jasmin 향은 활기차고 상쾌하고 유쾌하게 평가되었다. 뇌파 분석에서 lavendar 향을 주었을 때 theta의 증가 양상을 보였으며, Jasmin 향을 주었을 때는 모든 채널에서 beta 파의 증가 양상을 보였다. 또한 HRV 분석 결과 부교삼신경의 활동성이 부각되는 HF/LF의 값이 lavendar에서는 대조 자극보다 높게 나타났으며, jasmin에서는 대조자극보다 낮은 값이 나타나는 경향을 보였다. 결론적으로 안정과 각성의 후각 자극으로 인한 감성의 변화를 뇌파와 자율신경계 등의 생체지표로 관찰할 수 있었다.정하는 감성요인의 차이를 알 수 있었으며 또한 essential oil에서는 성별 차이가 없는데 반해 페르몬 향의 경우 성별의 차이를 나타내었다.. 방법을 타액과 혈청내 testosterone 농도 측정에 응용하여 RIA의 결과와 비교하여 본 바 상관관계가 타액에서 r=0.969, 혈청에서 r=0.990으로 두 결과가 잘 일치하였다. 본 실험에서 측정된 한국인 여성의 타액내 testosterone농도는 107.7$\pm$12.0 pmol/l이었고, 남성의 타액내 농도는 274.2$\pm$22.1 pmol/l이었다. 이상의 결과로 보아 본 연구에서 정립된 EIA 방법은 RIA를 대신하여 소규모의 실험실에서도 활용할 수 있을 것으로 사려된다.또한 상실기 이후 배아에서 합성되며, 발생시기에 따라 그 영향이 다르고 팽창과 부화에 관여하는 것으로 사료된다. 더욱이, 조선의 ${\ulcorner}$구성교육${\lrcorner}$이 조선총독부의 관리하에서 실행되었다는 것을, 당시의 사범학교를 중심으로 한 교육조직을 기술한 문헌에 의해 규명시켰다.nd of letter design which represents -natural objects and was popular at the time of Yukjo Dynasty, and there are some documents of that period left both in Japan and Korea. "Hyojedo" in Korea is supposed to have been influenced by the letter design. Asite- is also considered to have been "Japanese Letter Jobcheso." Therefore, the purpose of this study is to loo

  • PDF