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Gene Expression Profiling in the Nematode Caenorhabditis elegans, as a Potential Biomarker for Soil Ecotoxicology  

Roh, Ji-Yeon (Faculty of Environmental Engineering, College of Urban Science, University of Seoul)
Choi, Jin-Hee (Faculty of Environmental Engineering, College of Urban Science, University of Seoul)
Publication Information
Environmental Analysis Health and Toxicology / v.25, no.1, 2010 , pp. 1-10 More about this Journal
Abstract
Monitoring toxicity levels in specific biological compartments is necessary to evaluate the ecotoxicological risk associated with soil environmental pollution. Gene expression, as potential biomarker, is increasingly used as rapid early warning systems in environmental monitoring and ecological risk assessment procedures. Various representative species are currently used for the purpose of assessing soil toxicity, however, investigations on toxicological assessments using endpoint based on gene-level have been limited. In this review, we will present the current trends in organisms and endpoints used in soil toxicity study and report gene expression related to toxicity using soil organism, and C. elegans as promising organisms for this approach.
Keywords
gene expression profiling; Caenorhabditis elegans; soil ecotixicology;
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