• Title/Summary/Keyword: 생체적합도

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Piezoelectric Polymer Ultrasound Transducers and Its Biomedical Applications (압전고분자 초음파 트랜스듀서와 생의학적 응용)

  • Ha, Kang-Lyeol;Cao, Yonggang
    • Journal of the Korean Society for Nondestructive Testing
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    • v.32 no.5
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    • pp.585-596
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    • 2012
  • PVDF(poly vinylidene fluoride) and P(VDF-TrFE)(poly vinylidene fluoride-tetrafluoroethylene) are the typical piezoelectric polymers with unique properties. Even they are inferior to conventional piezoelectric ceramics PZT in electromechanical conversion efficiency and interior loss, though they are superior in receiving sensitivity and frequency bandwidth. Their acoustic impedances are relatively close to water or biological tissue and it is easier to make thin film than other piezoelectric materials. Futhermore, the film is so flexible that it is easy to attach on a complex surface. Those properties are suitable for the ultrasound transducers which are useful for medical and biological application, so that various types of polymer transducers have been developed. In this paper, several important considerations for design and fabrication of piezoelectric polymer transducers were described and their effect on the transducer performance were demonstrated through the KLM model analysis. Then, it was briefly reviewed about the structures of the polymer transducers developed for obtaining images as well as the characteristics of the images in several important medical and biological application fields.

A Iris Recognition Using Zernike Moment and Wavelet (Zernike 모멘트와 Wavelet을 이용한 홍채인식)

  • Choi, Chang-Soo;Park, Jong-Cheon;Jun, Byoung-Min
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.11
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    • pp.4568-4575
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    • 2010
  • Iris recognition is a biometric technology that uses iris pattern information, which has features of stability, security etc. Because of this reason, it is especially appropriate under certain circumstances of requiring a high security. Recently, using the iris information has a variety uses in the fields of access control and information security. In extracting the iris feature, it is desirable to extract the feature which is invariant to size, lights, rotation. We have easy solutions to the problem of iris size and lights by previous processing but there is still problem of iris feature extract invariant to rotation. In this paper, To improve an awareness ratio and decline in speed for a revision of rotation, it is proposed that the iris recognition method using Zernike Moment and Daubechies Wavelet. At first step, the proposed method groups rotated iris into similar things by statistical feature of Zernike Moment invariant to a rotation, which shortens processing time of iris recognition and looks equal to an established method in the performance of recognition too. therefore, proposed method could confirm the possibility of effective application for large scale iris recognition system.

Effects of Cutting Condition on Rooting and Growth of Cut Flower in Plug Cutting of Dendranthema grandiflorum 'Iwanohakusen' (국화 '백선'의 플러그 삽목시 삽수조건이 발근 및 절화생육에 미치는 영향)

  • Yoo, Yong Kweon;Roh, Yong Seung
    • FLOWER RESEARCH JOURNAL
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    • v.17 no.4
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    • pp.256-261
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    • 2009
  • This study was carried out to examine the effects of cutting condition on the rooting and their subsequent growth of cut flower in plug cutting of summer-flowering chrysanthemum 'Iwanohakusen'. The more leaves were attached to the cutting, the higher shoot growth and rooting were. Shoot growth of cuttings was not affected by cutting length, but rooting was better in over 5 cm long cutting. Shoot growth was enhanced by increasing thickness of cutting, and 5.5 mm thick cutting was favored in rooting. When the many leaves were attached on the cutting, the length and weight of cut flower increased. Over 7 cm long cutting showed higher values in growth of cut flower and ray flower number. Cutting of 5.5 mm diameter showed more favorable growth of cut flower than the other treatments. Therefore, it is concluded that rooting of cutting and consecutive growth of cut flower was improved when 7 cm long and 5.5 mm diameter cutting with 4 leaves was used in plug cutting of chrysanthemum 'Iwanohakusen'.

Fabrication of Porous Silk Fibroin Microparticles by Electrohydrodynamic Spraying (전기분사법에 의한 다공성 실크 피브로인 미세입자의 제조)

  • Kim, Moo Kon;Lee, Ki Hoon
    • Polymer(Korea)
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    • v.38 no.1
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    • pp.98-102
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    • 2014
  • Nowadays, silk fibroin receives a lot of attention as novel natural biomaterials due to its excellent biocompatibility and biodegradability. Electrohydrodynamic spraying (EHDS) is one of the method for the preparation of micro or nanoparticles by applying high voltage to the polymer solution. In this research, we fabricated silk fibroin porous microparticles by electrohydrodynamic spraying. Poly(ethylene glycol) (PEG) was added to the fibroin solution to give pores to silk fibroin microparticles. By the addition of PEG, the microparticle size was decreased despite of the decrease in conductivity and the increase of viscosity of the spraying solution. It seems that the immiscibility of silk fibroin and PEG affected much more to the microparticle size than the conductivity and viscosity. Immersing the as-sprayed microparticles into the water removed the phase-separated PEG, and finally, porous silk fibroin microparticles were prepared. The porous silk fibroin microparticles are expected to be applied as drug carriers in drug delivery or cell carriers in tissue engineering.

Preparation and Characterization of Tissue Engineered Scaffold Using Porcine Small Intestinal Submucosa and Hyaluronic Acid (돼지의 소장점막하 조직과 히알루론산을 이용한 조직공학적 담체의 제조 및 특성분석)

  • Lim, Ji-Ye;Kim, Soon-Hee;Kang, Gil-Son;Rhee, John M.
    • Polymer(Korea)
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    • v.32 no.5
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    • pp.415-420
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    • 2008
  • The porcine small intestinal submucosa (SIS) without immunorejection responses and hyalunonic acid (HA) can be used as biomaterials. In this study, we tried to design and characterize novel sponge. SIS- HA sponge was prepared by freeze-drying after addition 1wt% HA solution into fabricated SIS sponge. Sponge was crosslinked with 1-ethyl-(3-3-dimethyl aminopropyl) carbodiimide hydrochloride (EDC) solution with 100mM concentration for 24 hrs and lyophilized. SIS-HA sponge was characterized by scanning electron microscopy and fourier transform infrared spectrometer. And water absorption ability of sponge was evaluated. We seeded NIH/3T3 cells in SIS-HA sponge and cellular attachment was assayed by 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltertazolium-bromide (MTT) test. We demonstrated presence of HA in SIS-HA sponge from C-O functional group observed by the FT-IR analysis. Moreover, we confirmed low cytotoxicity and high cell viability of the SIS-HA sponges. Therefore, we could expect that SIS- HA scaffolds are applicable for the tissue regeneration.

Study of Superparamagnetic Microneedles containing Iron Oxide Nanoparticles (산화철 나노입자를 함유한 초상자성 마이크로니들에 관한 연구)

  • Lee, Seung-Jun
    • Applied Chemistry for Engineering
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    • v.32 no.5
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    • pp.556-561
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    • 2021
  • Recently, iron oxide nanoparticles have been used as the subject of many studies on drug delivery system (DDS) due to their excellent magnetic properties and biocompatibility in response to external magnetic fields. In this study, hyaluronic acid-superparamagnetic microneedles (HA-SMNs) and carboxy methyl cellulose-superparamagnetic microneedles (CMC-SMNs) containing superparamagnetic iron oxide nanoparticles (SIONs) were prepared with HA and CMC as a matrix materials of MNs (microneedles). Various properties of SMNs were then investigated with scanning electron microscopy (SEM), superconducting quantum interference device-vibrating sample magnetometer (SQUD-VSM), frequency mixing magnetic detection (FMMD), and polymer/bio membrane. The SQUID-VSM measurements showed superparamagnetism of HA-SMNs and CMC-SMNs containing SIONs. The FMMD results demonstrated that the signal intensity changed significantly as the concentration of SIONs increased. In addition, SMNs exhibited the average skin permeability intensities on the bio membrane for HA-SMNs and CMC-SMNs were 92.5 and 98.5%, respectively. These results suggested that SMNs could be utilized as deliver materials for a TDDS and MR molecular imaging.

Synthesis and Characterization of Amorphous Calcium Phosphate Nanoparticles (비정질 칼슘 포스페이트 나노 입자의 합성과 특성)

  • Han, Ji-Hoon;Chung, Sungwook
    • Applied Chemistry for Engineering
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    • v.29 no.6
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    • pp.740-745
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    • 2018
  • The synthesis and characterization of amorphous calcium phosphate (ACP) nanoparticles were reported in this work. We show that relatively monodisperse ACP nanoparticles with a size of sub-100 nm can be prepared by a hydrothermal reaction of calcium chloride ($CaCl_2$) and disodium adenosine triphosphate ($Na_2ATP$) in the presence of sodium phytate as an additive. Their compositions and structures were confirmed using a series of material characterization techniques. Our results exhibit that ACP nanoparticles synthesized using sodium phytate enhanced the stability of maintaining their amorphous nature and prevented from a conversion to crystalline hydroxyapatite (HAP). ACP nanoparticles with the improved stability have potential uses in biomaterial applications in regenerative medicine.

Overview of VR Media Technology and Methods to Reduce Cybersickness (가상현실 미디어 기술동향과 VR 멀미저감 방안)

  • Mun, Sungchul;Whang, Mincheol;Park, Sangin;Lee, Dong Won;Kim, Hong-Ik
    • Journal of Broadcast Engineering
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    • v.23 no.6
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    • pp.800-812
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    • 2018
  • In this study, we reviewed recent trends for enhancing human cognitive accessibility to social VR platform. We also proposed a practical method to predict VR sickness and improve the cognitive accessibility. In doing so, we investigated subtle changes in human body sway unconsciously made before, during, and after being exposed to extreme VR experience. The scientific assumption that VR sickness would be correlated with the subtle changes in body sway was validated. We found that participants who showed sensitive changes in the body sway before VR experience, felt more severe VR sickness than others. The findings can be practically applied in predicting susceptibility to VR sickness prior to VR experiences.

Application of Nanoparticles in Food Preservation and Food Processing

  • Prakash, J.;Vignesh, K.;Anusuya, T.;Kalaivani, T.;Ramachandran, C.;Sudha, Rani R.;Rubab, Momna;Khan, Imran;Elahi, Fazle;Oh, Deog-Hwan;DevanandVenkatasubbu, G.
    • Journal of Food Hygiene and Safety
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    • v.34 no.4
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    • pp.317-324
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    • 2019
  • This study focuses on the role of nanotechnology in the field of food industries. Bioactive components with antimicrobial activity against food pathogens are encapsulated into nanoparticles (NPs) to improve and extend their efficiency in food preservation. However, these NPs should be biocompatible and nontoxic for humans. Advancement in this field has resulted in the development of NPs for food packaging in some industries. The most commonly used group of NPs in the food industry is metal oxide. As metal oxide NPs such as zinc oxide and titanium dioxide exhibit antimicrobial activity in food materials, the NPs can be used for food preservation with enhanced functional properties. The application and effects of nanotechnology in correlation with the nutritional and sensory properties of foods were briefly discussed with a few insights into safety regulations on nano-based food formulation and preservation.

Elderly Speech Signal Processing: A Systematic Review for Analysis of Gender Innovation (노인음성신호처리: 젠더혁신 분석에 대한 체계적 문헌고찰)

  • Lee, JiYeoun
    • Journal of Convergence for Information Technology
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    • v.9 no.8
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    • pp.148-154
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    • 2019
  • The purpose of this study is to review systematically the literatures on the research of the elderly speech signal processing based on the domestic gender innovation and to introduce the utility and innovation of the gender analysis methods. From 2000 to present, among the 37 research papers published in the Korean Journal, 25 papers were selected according to the inclusion and exclusion criteria. And gender analysis methods were applied to gender research subject and design. Research results show diversity of research field and high gender recognition of R & D team are needed in research and development of engineering of gender innovation perspective. In addition, government-level regulation and research funding should be systematically applied to gender innovation research processes in the elderly voice signal processing and various gender innovation projects. In the future gender innovation in the elderly speech signal processing can contribute to the creation of a new market by developing a voice recognition system and service that reflects the needs of both men and women.