• Radiation Oncology Journal
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• v.18 no.3
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• pp.167-176
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• 2000

The objective of recent radiation therapy is to improve the quality of treatment and the after treatment quality of life. In Korea, sharing the same objective, significant advancement was made due to the gradual increase of patient number and rapid increase of treatment facilities. The advancement includes generalization of three-dimensional conformal radiotherapy (3D-CRT), application of linac-based stereotactic radiosurgery (SRS), and furthermore, the introduction of intensity modulated radiation therapy (IMRT). Authors in this paper prospectively review the followings: the advancement of radiation oncology in Korea, the recent status of four-dimensional radiation therapy, IMRT, the concept of the treatment with biological conformity, the trend of combined chemoradiotherapy, the importance of internet and radiation oncology information management system as influenced by the revolution of information technology, and finally the global trend of telemedicine in radiation oncology. Additionally, we suggest the methods to improve radiotherapy treatment, which include improvement of quality assurance (QA) measures by developing Koreanized QA protocol and system, regional study about clinical protocol development for phase three clinical trial, suggestion of unified treatment protocol and guideline by academic or research societies, domestic generation of treatment equipment's or system, establishment of nationwide data base of radiation-oncology-related information, and finally patterns-of-care study about major cancers.

• Korean Journal of Head & Neck Oncology
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• v.17 no.1
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• pp.3-7
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• 2001

Objectives: New photosensitizer 9-hydroxypheophorbide-$\alpha$(9-HpbD-$\alpha$) was derived from chlorophyll in water with peak absorption at 660nm. 9-HpbD-$\alpha$ was tested with 660 nm diode laser for the anticancer effect of photodynamic therapy. Materials and Methods: Human SNU 1041 cells were seeded into 96 well plate at a density of $$ cells/well for 24 hours. Cells were washed with media containing various concentration of 9-HpbD-$\alpha$ ranging from $0{\mu}g/ml\;to\;3.75{\mu}g/ml$. Then, laser treatment was done with 660nm diode laser ($10mW/cm^2$) at various time setting (0, 30, 60, 90, 120 minutes) and with various time interval (0, 1, 4, 6, 18 hours). The treated cells were incubated 48 hours and MTT assay was done to measure the viability of cells. Results: The viability of cells was more than 90% after laser treatment in control group. The viability of cells was decreased with increasing concentration of 9-HpbD-$\alpha$ and laser treatment time in experimental groups. The viability of cells was decreased significantly as the interval time between addition of 9-HpbD-$\alpha$ and laser irradiation was increased. Conclusion: This study shows the anticancer effect of photodynamic therapy using 9-HpbD-$\alpha$ and 660nm Diode laser on carcinoma cell line. 9-HpbD-$\alpha$ is considerd as one of new photo sensitizers in the field of photodynamic therapy.

• Journal of Oriental Neuropsychiatry
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• v.30 no.3
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• pp.185-198
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• 2019

Objectives: The purpose of this study was to identify the effectiveness of Korean medicine treatment in mild cognitive impairment (MCI) among a group of community dwelling elderly. Methods: Two-hundred and twenty-nine elderly living in a community and diagnosed with MCI were recruited. Participants were evaluated with various instruments such as the Korean version of Mini-Mental State Examination for Dementia Screening (MMSE-DS) and the Korean version of Montreal Cognitive Assessment (MoCA-K). Korean medicine treatment consisted of herbal medicine, acupuncture, and pharmacoacupuncture. The change in cognitive ability was assessed by using the MMSE-DS and the MoCA-K. Data were analyzed by SPSS/WIN 22.0 using the paired t-test, and the ANOVA. Results: The MMSE-DS and the MoCA-K score generally increased after six months of Korean medicine treatment and the differences in both instruments were statistically significant. Additionally, some consecutive participants maintained long-term cognitive improvement. When analyzed specifically by herbal medicine group based on syndrome differentiation and pharmacoacupuncture group, most showed improvement in the MMSE-DS and the MoCA-K but not all data were statistically significant. The satisfaction score was mostly high and most participants were willing to re-participate in the program. Conclusions: Korean medicine treatment may contribute to the improvement and prevention of cognitive decline in the elderly. However, further systematic research based on large scale sample data and standardized protocols is needed to uplift the welfare and mental health of the elderly.

• Korean Journal of Bronchoesophagology
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• v.15 no.1
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• pp.60-63
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• 2009

The photodynamic therapy (PDT) is a new treatment modality of destroying malignant tumors and pre-malignant lesions based on the use of photodynamical damage to tumor cells under the photochemical reactions. But the clinical reports of photodynamic application on the benign tumor of the internal organs were extremely rare. So we decribed our experience of one case of benign tracheal tumor successfully treated by PDT.

• Journal of Dental Rehabilitation and Applied Science
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• v.35 no.3
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• pp.160-169
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• 2019

Purpose: The purpose of this study was to evaluate the antimicrobial effects of a toothbrush with light-emitting diodes (LEDs) on periodontitis-associated dental biofilm attached to a zirconia surface by static and dynamic methods. Materials and Methods: Zirconia disks (12 mm diameter, 2.5 mm thickness) were inserted into a 24-well plate (static method) or inside a Center for Disease Control and Prevention (CDC) biofilm reactor (dynamic method) to form dental biofilms using Streptococcus gordonii and Fusobacterium nucleatum. The disks with biofilm were subdivided into five treatment groups-control, commercial photodynamic therapy (PDT), toothbrush alone (B), brush with LED (BL), and brush with LED+erythrosine (BLE). After treatment, the disks were agitated to detach the bacteria, and the resulting solutions were spread directly on selective agar. The number of viable bacteria and percentage of bacterial reduction were determined from colony counts. Scanning electron microscopy (SEM) was performed to visualize alterations in bacterial morphology. Results: No significant difference in biofilm formation was observed between dynamic and static methods. A significant difference was observed in the number of viable bacteria between the control and all experimental groups (P < 0.05). The percentage of bacterial reduction in the BLE group was significantly higher than in the other treated groups (P < 0.05). SEM revealed damaged bacterial cell walls in the PDT, BL, and BLE groups, but intact cell walls in the control and B groups. Conclusion: The findings suggest that an LED toothbrush with erythrosine is more effective than other treatments in reducing the viability of periodontitis-associated bacteria attached to zirconia in vitro.

• Journal of Society of Occupational Therapy for the Aged and Dementia
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• v.12 no.2
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• pp.67-74
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• 2018

Objective : The purpose of this study is to quantitatively analyze the role of occupational therapy in long - term care insurance for the elderly using text mining, one of the big data analysis techniques. Method : For the analysis of newspaper articles, "Long - Term Care Insurance for the Elderly + Occupational Therapy for the Elderly" was collected after the period from 2007 to 208. Naver, which has a high share of the domestic search engine, utilized the database of Naver News by utilizing Textom, a web crawling tool. After collecting the article title and original text of 510 news data from the collection of the elderly long term care insurance + occupational therapy search, we analyzed the article frequency and key words by year. Result : In terms of the frequency of articles published by year, the number of articles published in 2015 and 2017 was the highest with 70 articles (13.7%), and the top 10 terms of the key word analysis showed the highest frequency of 'dementia' (344) In terms of key words, dementia, treatment, hospital, health, service, rehabilitation, facilities, institution, grade, elderly, professional, salary, industrial complex and people are related. Conclusion : In this study, it is meaningful that the textual mining technique was used to more objectively confirm the social needs and the role of the occupational therapist for the dementia and rehabilitation in the related key keywords based on the media reporting trend of the elderly long - term care insurance for 11 years. Based on the results of this study, future research should expand research field and period and supplement the research methodology through various analysis methods according to the year.

• Journal of radiological science and technology
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• v.34 no.2
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• pp.131-140
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• 2011

This study is to investigate the satisfaction rate and relative factors from the students majored in Radiology, Clinical Pathology and Physical Therapy, which can provide basic knowledge of satisfaction and guide the university life and further careers. The survey was performed with respect to 107 students of Radiology, 97 of Clinical Pathology and 89 of Physical Therapy at three-year or four-year colleges(universities) located in Busan and Gyeongsangnam-do. The results show that the satisfaction rate through whole majors was $3.40{\pm}0.57$ point. The scores of each major are: $3.38{\pm}0.62$ for Radiology, $3.37{\pm}0.56$ for Clinical Pathology, and $3.45{\pm}0.50$ for Physical Therapy. The score of social status was highest and the environment of major was the lowest. The satisfaction of three-year colleges was higher than that of four-year universities. Academic system, social status and adaptation to major affected satisfaction on major. In addition job outlook affected on all majors. Thus, we propose that every major must be equipped with specialized environment different from general colleges (universities), and provide environment where students can cause self-motivation. In addition, we found the special way to improve social status and satisfaction by using career guidance, offering career information and performing university-industry collaborations. Especially, it is important to improve the satisfaction on major of students at four-year universities.

• The Journal of Korean society of community based occupational therapy
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• v.6 no.2
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• pp.31-38
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• 2016

Purpose : The purpose of this study was to know the relationship of stress and aggression of children with physical disability. The study also tried to search the factors affecting aggression and offer the information to the department of occupational therapy for intervention. Method : We distributed questionnaire to 105 children who have disability grades from hospitals in Gyeongsangbukdo, Gyeongsangnamdo, Daegu, and Busan and collected the data. We used descriptives for analysis of general characteristics, t-test and one-way ANOVA for stress and aggression according to characteristics, and Pearson correlation coefficient and stepwise regression for stress and aggression. Result : The first, stress score was 2.65, aggression was 2.53, and physical aggression was 3.01 that is the highest score in the items. The second, there was a significant difference of physical aggression(p=.021) in comparison of the grades. There was a significant difference of stress(p=.048), total aggression(p=.040), and physical aggression(p=.047) in comparison of gender. There was significant difference of stress(p=.035) and total aggression(p=.042) in satisfaction of school. The third, there was a significant correlation of total aggression(r=.475), physical aggression(r=.568), language aggression(r=.311), anger(r=.397), and hostility (r=.491) quantitatively in correlation of stress and aggression. The fourth, the factors affecting aggression of children with physical disability were stress, male, and satisfaction of school(F=61.187, p<.01). Conclusion : We knew that factors affecting aggression of children with physical disability were their stress and some of general characteristics.

• Tuberculosis and Respiratory Diseases
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• v.65 no.2
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• pp.137-141
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• 2008

We treated synchronous double primary lung cancers, where one site resulted from CIS disease, with lobectomy and argon plasma coagulation (APC) in a patient who couldn't tolerate pneumonectomy, which resulted in a reduction of the extent of surgery. APC could be a reasonable alternative for CIS disease of lung in inoperable patients.

• The Journal of Korean society of community based occupational therapy
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• v.10 no.2
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• pp.37-46
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• 2020

Objective : The purpose of this study is to examine the effect of cultural empathy, and personalities on cultural competence among university students of occupational therapy. Methods : One-hundred and fifty-five university students of occupational therapy in Jeollanamdo and Gwangju completed questionnaires consisting of a demographic questionnaire, the Scale of Ethnocultural Empathy(SEE), Big Fie Inventory(BFI), and (CCAI). To determine the relationships among demographic variables, cultural empathy, personalities, and cultural competence, descriptive statistics, Pearson correlation analysis, and regression analysis were analyzed by using SPSS 24.0 for Windows. Results : The results of the study showed the differences in neuroticism and conscientiousness by gender. Also, there were positive correlations between cultural empathy, personality, and cultural competence. Lastly, cultural empathy(β=.357), openness(β=.252), and school year(β=-.148)were significant predictors of cultural competence. Conclusion : The results of this study clarified the relationships among cultural empathy, personality, and cultural competence, and will provide data for the education program to enhance the cultural competence of undergraduates of occupational therapy.