• Title/Summary/Keyword: 과학확산

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Characteristics of Coagulase-negative Staphylococci Isolates from Dental Clinic Environments in Busan, Korea (부산지역 치과환경에서 분리된 coagulase-negative staphylococci의 특성)

  • Jung, Hye-In;Jung, So Young;Park, Indal;Bae, Il Kwon
    • Journal of Life Science
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    • v.26 no.2
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    • pp.220-225
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    • 2016
  • Coagulase-negative staphylococci (CNS) have recently become the bacteria most frequently found in clinical infections. The aim of this study was to investigate the prevalence, antimicrobial susceptibilities, and molecular characteristics of CNS isolates from dental clinic environments in Busan, Korea. One hundred and fifty-four samples were collected from 10 dental clinics and dental hospitals in Busan from December 2014 to January 2015. Species were identified by matrix-assisted laser desorption/ionization–time-of-flight. Antimicrobial susceptibility was determined by disk diffusion methods. A polymerase chain reaction was performed to detect mecA, mupA gene, and SCCmec types. Of the 154 samples, 10(6.5%) isolates were identified as CNS (5 Staphylococcus epidermidis, 2 Staphylococcus capitis, 2 Staphylococcus, and 1 Staphylococcus haemolyticus). Among the 10 isolates, 6 were resistant to penicillin, 5 were resistant to gentamicin, 3 were resistant to tetracycline, and 2 were resistant to cefoxitin and erythromycin. However, clindamycin, ciprofloxacin, teicoplanin, and trimethoprim-sulfamethoxazole resistant isolates were not present. Genes encoding mecA were detected in 4 (2 S. warneri and 2 S. haemolyticus) isolates, and mupA in 1 (S. epidermidis) isolate. One methicillin-resistant CNS (S. warneri) isolate was determined as being of the SCCmec type I. It is concluded that CNS resistant to various antimicrobial agents was widely distributed in dental clinic environments in Korea.

Toxins and Antibiotic Resistance of Methicillin-Resistant Staphylococcus aureus Isolated from Clinical Specimens (임상검체로부터 분리된 methicillin 내성 Staphylococcus aureus의 독소 및 항생제 내성)

  • Baik, Keun-Sik;Ki, Gwang-Seo;Choe, Han-Na;Park, Seong-Chan;Koh, Eun-Cho;Kim, Hyung-Rak;Seong, Chi-Nam
    • Journal of Life Science
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    • v.21 no.2
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    • pp.257-264
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    • 2011
  • Seventy five methicillin- resistant Staphylococcus aureus (MRSA) strains and 24 methicillin- susceptible S. aureus (MSSA) were isolated from clinical specimens obtained from a hospital in Suncheon, Jeonnam province, Korea, from July to December, 2009. Antibiotic resistance was determined using the disc diffusion method. Genes encoding enterotoxin (SE), toxic shock syndrome toxin-1 (TSST-1), exfoliative toxin (ET) and Panton-Valentine leukocidin (PVL) were detected by multiplex PCR-mediated amplification using specific primers. Sixty (80%) MRSA isolates possessed either one or more toxin genes and the most common pattern that coexisted in MRSA was seb, sec, seg, sei and tst (22.7%) followed by coexistence of sec, seg, sei and tst genes (18.7%). Gene pvl encoding leukocidin was not found. Significant correlation between the production of sec, seg, sei and tst genes was found. MRSAs were resistant to erythromycin (89% of the isolates), gentamicin (70.7%), ciprofloxacin (69.3%), clindamycin (61.3%) and tetracycline (58.7%), while MSSAs were susceptible to the antibiotics with the exception of erythromycin. Toxin genes seb, sec and tst were related to the tetracycline resistance of MRSA.

Construction of Component Repository for Supporting the CBD Process (CBD 프로세스 지원을 위한 컴포넌트 저장소의 구축)

  • Cha, Jung-Eun;Kim, Hang-Kon
    • Journal of KIISE:Software and Applications
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    • v.29 no.7
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    • pp.476-486
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    • 2002
  • CBD(Component Based Development) has become the best strategical method for the business application. Because CBD is a new development paradigm which makes it possible to assemble the software components for application, it copes with the rapid challenge of business process and meets the increasing requirements for productivity. Since the business process is rapidly changing, CBD technology is the promising way to solve the productivity. Especially, the repository is the most important part for the development, distribution and reuse of components. In component repository, we can store and manage the related work-products produced at each step of component development as well as component itself. In this paper, we suggested a practical approach for repository construction to support and realize the CBD process and developed the CRMS(Component Repository Management System) as implementation product of the proposed techniques. CRMS can manage a variety of component products based on component architecture, and help software developers to search a candidate component for their project and to understand a variety of information for the component. In the paper, a practical approach for component repository was suggested, and a supporting environment was constructed to make CBD to be working efficiently. We expect this work wall be valuable research for component repository and the entire supporting Component Based Development Process.

Analysis of Density Current in the Tidal River (감조하천(感潮河川)의 하구(河口) 밀도류해석(密度流解析))

  • Suh, Seung Duk;Park, Sung Bae
    • Current Research on Agriculture and Life Sciences
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    • v.4
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    • pp.70-76
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    • 1986
  • The purpose of this study is to offer the basic data of the tidal river development program by grasping the diffusion between the high density-sea water and the low density-fresh water in the tidal river. The tidal range of Hyungsan river which flows at Youngil bay in Pohang was selected to analysis the phenomenon of density current. The results obtained are as follows ; The tide of Youngil bay was one time a day, 0.104m in high tide difference and 0.085m in mean tidy difference. The change of sea level by tide was negligible. The volume of reserved water by sea water was $2,700,000m^3$ and available water of irrigation was $1,200,000m^3$ that salt density is below $750{\mu}{\mho}/cm$ out of total volume. Salt intrusion phenomenon by density current was a little water level change, however, it become a salt wedge type by the much salt invasion during the spring tide and it makes a well-mixed type by the retreating salt wedge during the neap tide. As long as there were some density differences between sea water and fresh water, net upstream flow was existed along the bottom of water way from the estuary to the upstream channel.

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Antioxidant Activities and Antimicrobial Effects of Extracts from Auricularia auricula-judae (목이버섯(Auricularia auricula-judae) 추출물의 항산화 활성 및 항균 효과)

  • Yu, Sang-Cheol;Oh, Tae-Jin
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.45 no.3
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    • pp.327-332
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    • 2016
  • This study investigated the antioxidant and antimicrobial activities of various solvents (acetone, ethyl acetate, and ethanol) for extraction of Auricularia auricula-judae. Antioxidant activity was evaluated by determining total polyphenol and flavonoid contents, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) cation radical scavenging activity. Total polyphenol and flavonoid contents were not significantly different among the extracts, whereas DPPH radical scavenging activity and ABTS cation radical scavenging activity were significantly higher in ethanol and acetone extracts. DPPH radical scavenging activities of ethanol and acetone extracts showed high values (58.7% and 46.7%, respectively). The antimicrobial properties of these extracts were determined against six bacterial pathogens (Bacillus subtilis, Staphylococcus aureus, Micrococcus luteus, Escherichia coli, Pseudomonas aeruginosa, and Enterobacter cloacae) by the disc diffusion method. The acetone extracts showed antimicrobial activities against all tested bacteria, and all extracts showed the highest antimicrobial activity against B. subtilis.

Focus Group Interview on Opinion about the Design and Management of Toothbrushing Facilities (양치시설 설계 및 운영에 대한 관련 실무자의 견해: 초점집단면접 연구)

  • Lee, Hyo-Jin;Paik, Dai-Il
    • Journal of dental hygiene science
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    • v.16 no.2
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    • pp.118-126
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    • 2016
  • This study collected opinions about the design and management of toothbrushing facilities from schoolteachers and the people in charge of public centers, through a focus group interview (FGI), for the development of guidelines. Four moderators conducted eight FGIs of 32 subjects in charge of toothbrushing facilities across all the regions. The qualitative data was analyzed by constant comparative analysis. The findings indicated that more students utilized the facility and brushed their teeth after the installation of toothbrushing facilities. To enhance students' accessibility and safety, guidelines for design and management guidelinesfor toothbrushing facilities need to be developed; the location, sink height and depth, drain size, etc. should be comprehensively considered in the development of the guidelines. This study can help to improve students' satisfaction by enhancing the accessibility, safety, and functionality of toothbrushing facilities, and by providing fundamental data for toothbrushing facilities' development. Finally, this study can maximize the effects of management of toothbrushing facilities management on the improvement of students' oral health and behaviors.

A Study of the Narrative Structure and the Writer's Intent in the Hasaenggiwoojun(何生奇遇傳) (<하생기우전>의 서사구조와 작가적 의미 - 갈등양상을 중심으로 -)

  • Moon, Beom-doo
    • Journal of Korean Classical Literature and Education
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    • no.37
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    • pp.111-149
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    • 2018
  • This story is written by Shin Kwang-han who is a famous scholar and writer in Josun Dynasty. The most notable feature of this story is the love between a man and a dead woman. The protagonist has failed the test to be a national official for several years, because of the corruption and unfairness of the leaders of his society. He is very upset, but then changes his mind in order to become an officer. One day he meets a dead woman. He saves her life from death, and falls in love with her. Finally he marries her and attains a high position. Till now, all the aspects of this story have been extensively researched from a number of different perspectives. However the narrative structure of this story has not been discussed much. This story belongs to Jungi-novel, a kind of old story style which includes fantasy. The studies on this story have mostly been carried out to find the different features in comparison with other works of the same style. Further, we could not understand its own specific meaning structure. This study aims to find the narrative structure of this story. It was recognized by researchers that Shin's stories talk about his life and his perspective of the world. Further, I will try to show how he expresses his thoughts, emotion and life through this story. First, to obtain a satisfactory result through this study, I will find a way to resolve several problems that have become the center of the controversy. Afterward, the conflict and resolution the hero's relation to the world will be identified in every paragraph. Through these efforts, we will have a new point of the view about the narrative structure of this story and the intent expressed by the writer through its structure.

Treatment of Early Laryngeal Cancer - Indication and Technique of Conservative Partial Laryngectomy - (초기 후두암의 치료 - 보존적 후두절제술의 적용범위와 방법 -)

  • 서장수;송시연
    • Korean Journal of Bronchoesophagology
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    • v.3 no.1
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    • pp.27-36
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    • 1997
  • 초기후두암에 있어서 보존적 술식의 장점은 후두 전적출술시와 같은 국소치료효과를 얻을 수 있으면서도 후두의 생리적 기능을 최대한 보존하는데 있다. 성공적인 후두부분절제술을 위해서는 후두내에서 종양의 발생위치 및 그 확산에 대한 연부조직들의 해부학적 역할에 대한 이해가 필요하다. 과거에는 초기후두암환자에서 정상적인 목소리를 보존할 수 있다는 이점 때문에 방사선 치료가 일차적 치료요법으로 많이 시행되어 왔다. Wang 과 Wong은 성대 막양부에 국한된 병변에서 방사선치료에 대한 5년간 조절율(5-year control rate)이 92%, 전연합부를 침범한 경우가 81%, 그리고 후방으로 전파된 경우 76%로 감소된다고 보고하였다. Olofsson 등은 전연합부를 침범한 57례의 환자에서 방사선 치료를 시행하여 85.7%의 5년 생존율을 얻었으나, 57례중 15례에서 재발하여 구제수술(salvage surgery)을 시행하였고, Jesse 등$^{13)}$ 은 전연합부를 침범한 91례의 T1, T2 성문암을 방사선 치료를 시행하여 8.8%의 실패율을 보였으나 22례의 환자에서 재발하여 후에 salvage surgery를 시행하였다. 그러나 Ogura 등은 피열 연골을 침범한 79례의 환자에서 보존적 수술을 시행한 결과 6례의 환자에서 재발하여 90%의 3-years control rate를 얻을 수 있었다고 보고하였다. 이처럼 병변이 전연합부, 피열연골 혹은 후방성문하부로의 침범이 있는 경우는 방사선 치료 효과가 떨어지고, 따라서 방사선 치료에 실패할 가능성이 보다 높기 때문에 비록 방사선 치료 후 실패한 경우에서 구제 수술을 시행할 수는 있지만 후두기능을 보존하려는 궁극적인 목표를 생각할 때 보존적 수술을 우선적으로 시행하는 것이 바람직하다고 할 수 있다. Biller 등은 방사선 요법에서 실패한 성문부 종양에서는 대부분 전적출술을 시행하지만 일부는 보존적 수술을 시행할 수 있다고 보고하였다. 이들은 반대측 성문부에 종양의 침범이 없어야 하고, 전연 합으로의 파급은 있어도 가능하며 성대돌기를 제외한 피열연골이 정상이어야 하고, 종양의 성문하부로의 파급이 5mm 이내라야 하며, 연골에 침범이 없어야 하고, 성대고정이 없어야 하며, 재발 병소가 방사선요법 전의 원발병소와 상관관계가 있어야 하며, 원발병소가 후두부분적출술에 합당할 경우 보존적 술식을 시행할 수 있다고 하였다. 최근에는 다양한 후두 재건술의 발달로 보다 진행된 후두암에 대한 보존적 후두절제술들이 소개되고 있다. 단측 T3,T4 후두암 혹은 경성문암, 이상와에 위치한 암의 경우 음성만을 재건하는 후두근적출술 (near total laryngectomy)을 시행하기도 한다. 본원 이비인후과에서 1986년부터 초기성문암 51례 중 24례(47.1%)와 초기성문상암 17례 중 12례 (70.6%)에 대하여 보존적 술식을 시행하였다. 초기 성문암의 보존적 술식을 시행한 24례중, 2례(8.3%)에서 경부재발, 1례(4.2%)에서 경부재발과 동반된 폐의 원격전이가 있었으나 원발부위의 재발은 관찰되지 않았고, 술후 합병증으로 1례(4.2%)에서 후두협착, 3례(12.5%)에서 수술부위의 육아종형성, 그리고 1례(4.2%)에서 기관지염이 발생하였으나 오연으로 인한 폐렴은 발생하지 않았다. 초기성문 상암의 보존적 술식을 시행한 12례 중 1례(8.3%)에서 원발병소의 재발, 2례(16.7%)에서 경부재발이 있었으며, 술후 합병증으로 3례(16.7%)에서 오연으로 인한 폐렴의 발생이 있었지만 다른 합병증은 발생하지 않았다. 초기성문암 24례 중 재발이 나타난 3례의 환자를 제외한 21례(97.5%)와 초기성문상암 12례 중 재발이 나타난 3례의 환자를 제외한 9례 (75%)에서는 현재까지 재발소견을 보이지 않고 있다. 이러한 결과는 다른 보고자들과 유사한 결과를 보이고 있지만 아직까지 증례가 많지 않기 때문에 생존율을 얻기에는 미흡한 점이 있으며, 향후 지속적인 추적관찰이 필요할 것으로 사료된다.

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A Study on the Application of BIPV for the Spread of Zero Energy Building (제로에너지 건축물 확산을 위한 건물 일체형 태양광 적용방안 연구)

  • Park, Seung-Joon;Jeon, Hyun-Woo;Lee, Seung-Joon;Oh, Choong-Hyun
    • Journal of Digital Convergence
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    • v.19 no.9
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    • pp.189-199
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    • 2021
  • In order to increase the self-reliance rate of new and renewable energy in order to respond to the mandatory domestic zero-energy buildings, the taller the building, the more limited the site area, and installing PV modules on the roof is not enough. Therefore, BIPV (Building integrated photovoltaic, hereinafter BIPV) is the industry receiving the most attention as a core energy source that can realize zero-energy buildings. Therefore, this study conducted a survey on the problems of the BIPV industry in a self-discussing method for experts with more than 10 years of experience of designers, builders, product manufacturers, and maintainers in order to suggest the right direction and revitalize the BIPV industry. Industrial problems of BIPV adjustment are drawn extention range of standard and certification for products, range improvement for current small condition of various kind productions, need to revise standards for capable of accomodating roof-type, color-module and louver-module, necessary of barrier in flow of foreign modules into korea through domestic certification mandatory, difficulty in obtaining BIPV information, request to prevent confusion among participants by exact guidelime about architectural application part of BIPV, and lack of the BIPV definition clearness, support policy, etc. Based on the improvements needed for the elements, giving change and competitiveness impacts aims to present and propose counter measures and direction.

A Study on the Characteristics and Policy Demand of the Unmanned Vehicle Industry in Gyeonggi-do (경기도 무인이동체 산업 특성과 정책수요)

  • Kim, Myung Jin
    • Journal of the Economic Geographical Society of Korea
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    • v.24 no.3
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    • pp.283-299
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    • 2021
  • As the intelligent revolution triggered by digital technology, unmanned vehicles such as self-driving cars, robots, and drones appeared, which brought about innovative changes in the industry. Gyeonggi Local government has established both an ordinance and a basic plan regarding unmanned vehicles. It is time to prepare a data-based policy by understanding the current state of the unmanned vehicle industry in the province. As a result of the survey, the unmanned vehicle industry in Gyeonggi Province is 25% of the nationwide, and more than 88% is concentrated in the southern part of Gyeonggi Province. The land sector such as the robot and autonomous vehicles are focused on 71.4% and the aviation sector such as drones are 26.7%. However, unmanned vehicle companies in Gyeonggi-do are mostly small-sized businesses with less than 10 years of experience and are in the stage of introduction and growth level. They have a plan to improve technology through continuous R&D by hiring human resources. Therefore, Gyeonggi-do needs to consider policy support for sustainable growth of start-up and small enterprises and for fostering professional manpower and technical skills as well as for establishing an unmanned vehicle industry network to create, share, and spread knowledge.