• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.25 no.3
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• pp.231-238
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• 2007

This paper describes the availability of the forthcoming integrated GNSS(Global Navigation Positioning System) positioning that includes GPS(Global Positioning System), Galileo, and QZSS(Quasi-Zenith Satellites System). We built a signal propagation model that identifies direct, multipath, and diffraction signals, using the principles of specular reflection and ray tracing technique. The signal propagation model was combined with 3D GIS(three-dimensional geographic information system) in order to measure the satellite visibility and positioning error factors, such as the number of visible satellites, average elevation of visible satellites, optimized DOP(dilution of position) values, and the portion of multipath-producing satellites. Since Galileo and QZSS will not be fully operational until 2010, we used a simulation in comparing GPS and GNSS positioning for a $1km{\times}1km$ developed area in Shinjuku, Tokyo. To account for local terrain variation. we divided the target area into 40,000 $5m{\times}5m$ grid cells. The number of visible satellites and that of multipath-free satellites will be greatly increased in the integrated GNSS environment while the average elevation of visible satellites will be higher in the GPS positioning. Much decreased PDOP(position dilution of precision) values indicate the appropriate satellite/user geometry of the integrated GNSS; however, in dense urban areas, multipath mitigation will be more important than the satellite/user geometry. Thus, the efforts for applying current technologies of multipath mitigation to the future GNSS environment will be necessary.

• Journal of Marine Bioscience and Biotechnology
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• v.8 no.1
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• pp.18-23
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• 2016

It is important to design photobioreactor by cheap material for economical microalgal biomass production. In this study, two types of marine photobioreactors (MPBR), made by either polyvinyl chloride (MPBR-PVC) or high density poly ethylene (MPBR-HDPE), are used and performance of these were compared. Tetraselmis sp. KCTC 12236BP is a green marine alga that isolated from Ganghwa Island, Korea, and the strain was used for marine cultivations using MPBR-PVC and MPBR-HDPE. The cultivations were performed three times in the spring season of 2012 using MPBR-PVC and of 2013 using MPBR-HDPE in the coastal area of Young Heung Island. As the results, MPBR-PVC shows higher biomass productivities than MPBR-HDPE, due to its high light transmittance. In the cultivations using MPBR-PVC, the average sea water temperature was $11.5^{\circ}C$ during the first experiment and $16.5^{\circ}C$ during the second and third experiments. Average light intensities during three times for experiments were 407.5, 268.1 and $273.0{\mu}{\cdot}E{\cdot}m^{-2}{\cdot}s^{-1}$, respectively. The maximum fresh cell weight and average biomass productivity were $1.2g{\cdot}L^{-1}$ and $0.12g{\cdot}L^{-1}{\cdot}day^{-1}$. These results showed that Tetraselmis sp. KCTC12236BP were adapted well with the environmental conditions from ocean, and grow in the MPBR-PVC and MPBR-HDPE.

• Journal of Life Science
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• v.21 no.1
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• pp.22-30
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• 2011

Apolipoprotein A-I (apoA-I) has anti-inflammatory and anti-oxidative properties. This study was designed to investigate whether apoA-I affects apoptosis and cytokine production of human blood neutrophils in an in vitro culture system. Spontaneous apoptosis of neutrophils was significantly delayed by apoA-I. In addition, high density lipoprotein containing apoA-I also delayed apoptosis of neutrophils. Apoptosis of neutrophils was inhibited by anti-scavenger receptor type B-I antibodies. The amounts of interleukin-8, interferon (IFN)-inducible protein 10 (IP-10), and tumor necrosis factor-$\alpha$ (TNF-$\alpha$) in the supernatants of cultured neutrophils treated with apoA-I were significantly increased. Combined treatment of neutrophils with IFN-$\gamma$ and apoA-I produced higher amounts of IP-10 and TNF-$\alpha$ than did treatment with IFN-$\gamma$ or apoA-I alone. The present study reveals that apoA-I activates neutrophils to produce cytokines and delays spontaneous apoptosis of neutrophils. These findings suggest that apoA-I, although a well-known negative acute-phase protein, has a pro-inflammatory effect in neutrophils.

• Journal of the Korean earth science society
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• v.30 no.2
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• pp.247-256
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• 2009

Characteristics of hydrography and tidal currents were investigated in Hampyung Bay through in situ CTD data, tidal currents and elevations. According to the seasonal weather variability, hydrography showed the lower density with high temperature and low salinity in summer and the higher density with low temperature and high salinity in winter. In particular, the thermal structure like a tidal front was formed along the central channel at the neap tide of summer. The critical value of the parameter $SH(=log_{10}(H/U^3)$ where H is depth and U is $M_2$ tidal current amplitude) representing the formation position of tidal front was estimated from 2.4 to 3.5. In addition, the potential energy anomaly $({\phi})$ was ranged between 0.985 and 6.998 Joule/$m^3$, which gradually increased from the mouth into the inner bay. This front may be caused by the unique topography with wide tidal flat and the local difference of tidal current strength. The observed tidal currents at the mouth of bay showed that the ebb time was shorter than the flood time with the increase of depth. This asymmetric ebb-tide dominance is interpreted as a result of tidal distortion by the development of a shallow-water-constituent in Hampyung Bay with a wide macro-tidal flat.

• KSBB Journal
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• v.15 no.5
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• pp.482-488
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• 2000

The Fab fraction of PDC-E2 specific human monoclonal antibody was produced using recombinant E. coli, and the effects of glucose and acetate were investigated to develop an optimal strategy for recombinant human antibody production. Higher glucose concentration in the culture media resulted inn higher cell growth and glucose consumption rate, which in turn resulted in an increased acetate production rate. When glucose was depleted, cells began to consume acetate as an energy source, and this consumption rate depended on the glucose concentration. When the residual glucose concentration was high, the accumulation of acetate was accelerated due to an increase in the acetate production rate and a decrease in the acetate consumption rate. Futhermore, it was found that a high accumulation of acetate, accompanied by a high glucose concentration, inhibited human antibody formation; the critical acetate concentration was $0.6g/\ell$. During production, a high glucose concentration enhanced cell growth, but inhibited antibody formation due to catabolic repression. Therefore, it is important to keep the concentration of both glucose and acetate as low as possible to increase antibody production after induction. Accordingly, it is important to accurately control the concentration of glucose and acetate in the culture media to obtain high cell densities and high productivity levels of recombinant human antibody.

• Korean Chemical Engineering Research
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• v.45 no.3
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• pp.249-257
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• 2007

The periodic square wave (PSW) model was successfully applied to the optimal design of a batch-storage network. The network structure can cover any type of batch production, distribution and inventory system, including recycle streams. Here we extend the coverage of the PSW model to multitasking semi-continuous processes as well as pure continuous and batch processes. In previous solutions obtained using the PSW model, the feedstock composition and product yield were treated as known constants. This constraint is relaxed in the present work, which treats the feedstock composition and product yield as free variables to be optimized. This modification makes it possible to deal with the pooling problem commonly encountered in oil refinery processes. Despite the greater complexity that arises when the feedstock composition and product yield are free variables, the PSW model still gives analytic lot sizing equations. The ability of the proposed method to determine the optimal plant design is demonstrated through the example of a high density polyethylene (HDPE) plant. Based on the analytical optimality results, we propose a practical process optimality measure that can be used for any kind of process. This measure facilitates direct comparison of the performance of multiple processes, and hence is a useful tool for diagnosing the status of process systems. The result that the cost of a process is proportional to the square root of average flow rate is similar to the well-known six-tenths factor rule in plant design.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.4C
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• pp.413-423
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• 2003

The CMA algorithmis most widely investigated blind algorithm and the most widely used one in practice. But, since nonlinear CM cost function have not closed form solution about the optimum weight. There have been difficultiesto analyze the CMA equalizer's theoretical performance. Recently, Zeng presents the notable theoretical resultabout the MSE of CM-minimizing estimators for the FIR linear channel in the presence of AWGN. Through this method, It wouldbe possible to campare the theoretical performance between CMA and Wiener equalizer in terms of MSE. In this paper, based on Zeng's method, we first calculate the theoretical MSE bound of CMA equalizer in partial response channel which is widely used in HDD, digital VCR such as high-density digital recording.playback systems. We confirmedthis result withthe computer simulation. Except this, we also performedthe theoretical and simulation analysis about the modified CMA equalizer, which was proposed to improve the performance of CMA equalizer in partial response channel. Finally, we compare and evaluate the performance analysis results between CMA and Modified CMA equalizer.

• Journal of the Microelectronics and Packaging Society
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• v.6 no.2
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• pp.37-43
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• 1999

Modules of the system that requires large capacity and high-speed information processing are implemented in the form of MCM that allows high-speed data processing, high density circuit integration and widely applied to such fields as ATM, GPS and PCS. Hence we developed the ATM switching module that is consisted of three chips and 2.48 Gbps data throughput, in the form of 10 multi-layer by Cu/Photo-BCB and 491pin PBGA which size is $48 \times 48 \textrm {mm}^2$. hnologies required for the development of the MCM includes extracting parameters for designing the substrate/package through the interconnect characterization to implement the high-speed characteristics, thermal management at the high-density MCM, and the generation of the testability that is one of the most difficult issues for developing the MCM. For the development of the ATM Switching MCM, we extracted signaling delay, via characteristics and crosstalk parameters through the interconnect characterization on the MCM-D. For the thermal management of 15.6 Watt under the high-density structure, we carried out the thermal analysis. formed 1.108 thermal vias through the substrate, and performed heat-proofing processing for the entire package so that it can keep the temperature less than $85^{\circ}C$. Lastly, in order to ensure the testability, we verified the substrate through fine pitch probing and applied the Boundary Scan Test (BST) for verifying the complex packaging/assembling processes, through which we developed an efficient and cost-effective product.

• Journal of the Microelectronics and Packaging Society
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• v.19 no.2
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• pp.67-72
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• 2012

In recent days, the wire width of IC is narrowed and the degree of integration of IC is increased to obtain the higher capacity of the devices in electronic industry. And then the surface quality of FCCL(Flexible Copper Clad Laminate) became increasingly important. Surface defects on FCCL are bump, scratch, dent and so on. In particular, bumps cause low reliability of the products. Even though there are bumps on the surface, if leveling characteristic of plating solution is good, it does not develop significant bump. In this study, the leveling characteristics of additives are investigated. The objective of study is to improve the leveling characteristic and reduce the surface step through additives and plating conditions. The additives in the electrodeposition bath are critical to obtain flat surface and free of defects. In order to form flat copper surface, accelerator, suppressor and leveler are added to the stock solution. The reason for the addition of leveler is planarization surface and inhibition of the formation of micro-bump. Levelers (SO(Safranin O), MV(Methylene Violet), AB(Alcian Blue), JGB(Janus Green B), DB(Diazine Black) and PVP(Polyvinyl Pyrrolidone) are used in copper plating solution to enhance the morphology of electroplated copper. In this study, the nucleation and growth behavior of copper with variation of additives are studied. The leveling characteristics are analyzed on artificially fabricated Ni bumps.

• Journal of Navigation and Port Research
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• v.30 no.5 s.111
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• pp.415-420
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• 2006

Urinalyses have been conducted for 28 crew's in H University's training ship and creatine and uric acid turned out to be higher in all ages, which can be inferred that board job has caused negative impact on kidney and/or malfunction In addition, TC and HDL-C, LDL-C ha; decreased, however, TG has increased after the navigation. All different positions including officer, crew, decker, engineer and radio part showed the similar pattern TC and HDL-C has decreased in 30s, 40s and TG has increased in 30s. A few of the 30's show extremely high TG rates so hyperlipidemia is suspected. 7 members turned out positive for UBG test and 5 positive for PRO test. Especially there was only one UBG positive before the navigation but, 7 members has become positive, which means the one-month long-tenn navigation has definite impact on the liver cell function.