• Title/Summary/Keyword: 'Special'

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Effects of processing method on the pharmacokinetics and tissue distribution of orally administered ginseng

  • Chen, Jianbo;Li, Meijia;Chen, Lixue;Wang, Yufang;Li, Shanshan;Zhang, Yuwei;Zhang, Lei;Song, Mingjie;Liu, Chang;Hua, Mei;Sun, Yinshi
    • Journal of Ginseng Research
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    • v.42 no.1
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    • pp.27-34
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    • 2018
  • Background: The use of different methods for the processing of ginseng can result in alterations in its medicinal properties and efficacy. White ginseng (WG), frozen ginseng (FG), and red ginseng (RG) are produced using different methods. WG, FG, and RG possess different pharmacological properties. Methods: WG, FG, and RG extracts and pure ginsenosides were administered to rats to study the pharmacokinetics and tissue distribution characteristics of the following ginsenosides-DRg1, Re, Rb1, and Rd. The concentrations of the ginsenosides in the plasma and tissues were determined using UPLC-MS/MS. Results: The rate and extent of absorption of Rg1, Re, Rb1, and Rd appeared to be affected by the different methods used in processing the ginseng samples. The areas under the plasma drug concentration-time curves (AUCs) of Rg1, Re, Rb1, and Rd were significantly higher than those of the pure ginsenosides. In addition, the AUCs of Rg1, Re, Rb1, and Rd were different for WG, FG, and RG. The amounts of Rg1, Re, Rd, and Rb1 were significantly (p < 0.05) higher in the tissues than those of the pure ginsenosides. The amounts of Re, Rb1, and Rd from the RG extract were significantly higher than those from the WG and FG extracts in the heart, lungs, and kidneys of the rats. Conclusion: Our results show that the use of different methods to process ginseng might affect the pharmacokinetics and oral bioavailability of ginseng as well as the tissue concentrations of Rg1, Re, Rd, and Rb1.

Discovering Research of Special Agency of National R&D Management by Analyzing the Current Management System of National R&D Program (연구관리 전문기관의 실태분석을 통한 유형화에 관한 탐색적 연구)

  • Lee, Gil-Woo;Chon, Se-Bong;Ko, Yun-Mi
    • Journal of Korea Technology Innovation Society
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    • v.12 no.1
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    • pp.1-35
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    • 2009
  • This study analyzes the current status of how to manage the national R&D program and the systematic problems of R&D planning, evaluation, and management, and then shows the strategy to support special agency of national R&D management for effective operation. Additionally, this study seeks to search for the macro methods to coordinate and to develop the roles and functions of special agency of national R&D management, and to promote efficiency and productivity of the National R&D investment. First of all, this study generally introduces the national R&D and surveys each special agency of national R&D management by analyzing the status of each agency charged by Ministry. Also, this study defines special agency of national R&D management by investigating each agency's status based on law and finds out the strategy to support special agency of national R&D management for effective operation. Each special agency of national R&D management is based on acts, administrative orders, or blanket contracts and takes whole charge of each National R&D program. The organization forms of special agency of national R&D management can be classified into two forms: One is a form to plan, to evaluate, and to manage the National R&D program and other is a form to research program together with the functions of planning, evaluation, and management. Therefore, this study defines special agency of national R&D management as "an organization, having a legal basis(acts, administrative orders), funded and charged by government for executing R&D planning, evaluation and management of R&D program." This study shows the strategy to operate special agency of national R&D management efficiently by analyzing each agency's current status and comparing each agency with each other. Moreover, every agency has a committee member pool, and the pool is classified well according to the fields of work and technology. Also, the special agency of national R&D management has its own organization to manage performances of program.

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Quality Characteristics of Yanggaeng Added with Paprika Powder (파프리카 분말을 첨가한 양갱의 품질 특성)

  • Park, Eun-Young;Kang, Seon-Gyeong;Jeong, Chang-Ho;Choi, Sang-Do;Shim, Ki-Hwan
    • Journal of agriculture & life science
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    • v.43 no.4
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    • pp.37-43
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    • 2009
  • This study investigated the quality characteristics of Yanggaeng with addition of paprika powders prepared by Special cultivar and Fiesta cultivar, respectively. The proximate composition, water activity, color, texture and sensory evaluation of Yanggaeng containing 1, 2, and 4% of each paprika powder were measured. A proximate composition of Yanggaeng with addition of paprika powders showed in the order of nitrogen free extract, moisture, crude protein, crude fat, and crude ash. The moisture of Special and Fiesta cultivar showed about 0.9. The lightness of Yanggaeng decreased with increasing addition levels of paprika powder and redness of Special cultivar increased with increasing addition levels of paprika powder. And yellowness of Yanggaeng increased with increasing addition levels of paprika powder. In the texture profile analysis, the hardness and adhesiveness of two Yanggaeng increased with increasing addition levels of paprika powder. Also the overall sensory evaluation showed best acceptability when paprika powder was added at 1% level into Yanggaeng.

A Comparative Study on the Revised Bills of the Regulatory Freedom Special Districts Act (focused on the Revised Bills by Proposed Kim Kyung-soo, Jung Sung-ho, Choo Kyung-ho, Hong Il-pyo) (규제자유특구법 개정안의 비교 고찰 (김경수, 정성호, 추경호, 홍일표, 개정안을 중심으로))

  • Kang, Min-Su;Choi, Ho-Sung;Cho, Han-Jin
    • Journal of the Korea Convergence Society
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    • v.10 no.3
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    • pp.203-209
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    • 2019
  • Special Act on Regulatory Freedom Zone and Regional Special Development Zonet" introduced a new type of 'Freedom Special Zone of Regulation' that is legally distinguished from the existing Special Districts for Regional and Regional Development to support the innovative and strategic growth of the areas, and even passed a number of legal grounds for providing innovative regulations for regional development projects or regional strategic industries within the Special Districts. Starting with the bill legislation proposed by The Parliament Members, Kim Kyung-soo on behalf of 33 suggestors, Choo Kyung-ho, Jung Sung-ho and Hong Il-pyo submitted the bill legislation on behalf of 10 to 12 proposers, respectively. As a major matter of issue, the purpose, designation, scope of application, promotion system, application of A Bill of Three kind on Regulatory Innovation, and Balanced National Development, many kind of regulation as like types of menu, special cases, punitive regulations, and so on have been argued until the end of the bill proposed from the beginning. In this study, the differences between the bill suggested by the Parliament members and bill approved already are to be compared and analyzed to confirm how the items on issue were reflected for the bill finally and to draw up measures for the correct operation of the special regulations.

A Study on the Operation of Curriculum for Students with Developmental Disabilities Perception of Special Class Teachers and Integrated Class Teachers (특수교육대상학생 교육과정 운영에 대한 특수학급 교사 및 통합학급 교사의 인식)

  • Jeon, Hae-In;Jeong, Hyo-Chul
    • The Journal of the Korea Contents Association
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    • v.21 no.5
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    • pp.268-275
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    • 2021
  • In special education, the operation of curriculum for students subject to special education is a role given to special teachers and integrated class teachers, and there are prior studies that many teachers experience difficulties in operating the curriculum. In this study, it was intended to find out the direction of special education courses and appropriate support measures for the operation of special education courses by exploring the experiences of special teachers and integrated class teachers, difficulties and suggestions in operating the curriculum. Participants in this study were special and integrated teachers with more than 15 years of experience, and all interviews were conducted in one-on-one in-depth interviews. After all the interviews have been prepared in full-length versions, the analysis has resulted in six major subjects and twelve subtopics; each teacher has different curriculum operations, difficulties in applying the curriculum, insufficient support systems, professional qualifications, and daily concerns of teachers in integrated classes. In the discussion, the direction of operation of special education courses for students and appropriate support measures for the operation of curriculum were discussed, and the limitations of research were presented and proposed.

An Exploratory Study on Decisions by foster Parents to care for Children with Special Needs : The Case of 'H' Foster Agency (특수욕구를 가진 아동에 대한 일반위탁부모의 위탁의사: 'H위탁보호기관'의 사례를 중심으로 한 탐색적 연구)

  • Kim, Bong-Sun;Jung, Hee-Young
    • Journal of Families and Better Life
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    • v.24 no.5 s.83
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    • pp.141-159
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    • 2006
  • It is generally blown that foster children often have special needs such as disability and psycho-behavioral problems. It is also known that foster parents will provide better care with those children when they are coping well with foster children with special needs. The purpose of the study was to explore the perceptions foster parents have and what factors affect their decisions to care for children with special needs. Literature review reveals that successful foster parent care is related to the foster parents' motivation, role perception, and social support systems. foster parents' motivation is related to 'altruism toward foster child', 'the egocentrism of the foster parent', 'previous experience with adoption' and 'the past experiences of the foster parent'. Role perceptions of the foster parent consist of 'supporting the internal system of the foster child' and 'supporting the external system of the foster child'. The social support system is characterized as the limited notions of a family oriented concept. In addition, a foster parent's decision to look after special-needs children is related to their motivation while the decision to foster disabled children is related to the levels of available social support systems as well as motivation. The results of the study implies that the motivation level and that of social support system are closely related to different aspects of the special-needs foster child; this factor should also be considered when recruiting foster parents or placing special needs children.

A Study on the Traditional Korean Special Costumes in Accordance with Climatic Factors of the Korean Peninsula - Focusing on Costumes of the Commoners in the Joseon Dynasty Period - (한반도의 기후적 요인에 따른 한국 전통 특수의상연구 - 조선시대 기층민 복식을 중심으로 -)

  • Hong, Bo Ra;Kan, Ho Sup
    • Journal of the Korean Society of Costume
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    • v.66 no.3
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    • pp.107-120
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    • 2016
  • This study examines functions in traditional Korean special costumes in accordance with the climatic factors of the Korean peninsula. The study focused on clothes worn by commoners during the Joseon dynasty. Climate change has been a major global issue in recent times, and it has been a hot topic in social, cultural, scientific, economic, and industrial communities. Studies have been conducted regarding the rapidly changing climate, and finding ways to cope with unusual temperatures. This thesis studies the development of special costumes in preparation for unusual climates, and requirements of the costume in accordance with the climatic factors, as well as the direction of its development. Its biggest significance lies in collecting and organizing the research data on special costume studies, and on costumes of the commoners, which have been fairly insufficient up to this point. After the Little Ice Age, the Joseon Dynasty period faced poor external environment due to unusual temperatures. The results of studying the costumes of the commoners are as follows: The climate of the Korean peninsula displayed different characteristics depending on the season, so the form, material, and appearance of the seasonal clothing items showed clear differences, and the difference in the crops cultivated according to the climate led to difference in material and material preference shown in the costumes. This meant that costumes differed based on region. In addition, difference in social hierarchy, regulations on costume according to class, and farming oriented social background during the period of Joseon dynasty slowed the development of costumes of commoners, but appears to have had a positive effect on the development of special costumes. We anticipate more succeeding studies on costumes of the commoners and special costumes in the future. We hope more costumes that can wisely respond to the approaching changes in temperature in the Korean peninsula can be designed via modernization of traditional Korean special costumes.

A Study on Economic Valuation Model of Special Libraries (전문도서관 서비스의 경제적 가치평가를 위한 분석모형 개발)

  • Chung, Hye-Kyung
    • Journal of the Korean Society for information Management
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    • v.22 no.3 s.57
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    • pp.147-162
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    • 2005
  • This study aims to suggest a new approach to economic valuation of the special library, in response to the necessity of economic justification of the special library operated by firms and research institutes. Benefit measurement elements and analysis methods to be used in the study were derived through feasibility evaluation on models in previous studies, and objectivity and applicability were the criteria for feasibility evaluation. Depending on which type of resources are used in providing service, different benefit measurement elements and methods were applied. Based on this, calculation formula for service valuation of special library was presented. The development of analysis model for economic valuation of special library made it possible to objectively prove the value of the special library, and is considered to provide an opportunity to publicize the real value of the special library.

A Study on the Education for Teacher Librarians in Inclusive Educational Environment (통합교육환경에서의 사서교사 교육에 관한 연구)

  • Kang, Sook-Hee
    • Journal of Korean Library and Information Science Society
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    • v.43 no.1
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    • pp.1-25
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    • 2012
  • In recent years, inclusion of students with disabilities in regular classrooms and special classrooms in mainstream schools has been a major stream of special education. However education for teacher librarians in Korea has not been responsive to these trends. A few of departments of library & information science in Korea universities offer courses that include information about special needs students. This study addressed the implications of inclusive education, the roles of school library and the training needs of teacher librarians for service to special needs students. And it analyzed tendency and current states of teacher librarians education on inclusive education. As a result, it is recommended that departments of library & information science in Korean universities offer more courses concerning educational support for special needs students in their curriculum and include of special modules in their most of courses offered to enhance the skill of future teacher librarians to cater for special educational needs.

Exploring Various Factors on Special Teacher's Adoption Intention towards Robot-based Education (특수교사의 로봇활용교육에 대한 수용의도에 영향을 미치는 요인 탐색)

  • Kim, Tae-Jun;Lee, Tae-Su
    • The Journal of the Korea Contents Association
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    • v.18 no.7
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    • pp.38-48
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    • 2018
  • The purpose of this study was to identify various factors that could possibly influence special teachers' adoption intention towards robot-based education and to see how well those factors predict special teachers' adoption intention. To do this, questionnaire items were selected and reconstructed based on preceding research relating to Technology Acceptance Model(TAM). The survey participants consisted of 623 special school teachers, representing various types of special students and levels of their schools. Questionnaires with unfaithful responses were excluded, and a total of 590 questionnaires were analyzed. Data analysis was carried out through Exploratory factor analysis and stepwise multi-regression analysis. According to the results of study, factors that influence special teachers' acceptance intention towards robot-based education are perceived ease of use, perceived usefulness, personal innovation, and social influence. Also, the most decisive factors affecting special teacher's acceptance intention were perceived usefulness and perceived ease of use. These factors directly influenced special teachers' acceptance intention.