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Antioxidative and Cellular Protective Effects of Dolwoe (Gynostemma pentaphyllum Makino) Extracts against Oxidative Stress (돌외(Gynostemma pentaphyllum Makino) 추출물의 산화적 스트레스에 대한 항산화 및 세포보호효과)

  • Kim, Kyoung Mi;Kim, A-Rang;Kim, A-Young;Ha, Ji Hun;Xuan, Song Hua;Jeong, Yoon Ju;Park, Young Min;Jeong, Hyo Jin;Hong, In Gi;Park, Soo Nam
    • Korean Journal of Pharmacognosy
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    • v.48 no.2
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    • pp.125-133
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    • 2017
  • In this study, we investigated the total phenolic and flavonoid contents, component analysis, antioxidative activity and cellular protective effects against oxidative stress on human skin cells in 50% ethanol extract, ethyl acetate fraction and aglycone fraction obtained from Gynostemma pentaphyllum (G. pentaphyllum) Makino. The DPPH (1,1-diphenyl-2-picrylhydrazyl) scavenging activites ($FSC_{50}$) of the 50% ethanol extracts, ethyl acetate fraction and aglycone fraction were 246.8, 147.2, $128.9{\mu}g/mL$, respectively. Reactive oxygen species (ROS) scavenging activities ($OSC_{50}$) of the 50% ethanol extract, ethyl acetate fraction and aglycone fraction on ROS generated in $Fe^{3+}-EDTA/H_2O_2$ system using the luminol-dependent chemiluminescence assay were 37.15, 10.74, $7.19{\mu}g/mL$, respectively. We investigated the cellular protective activity and the results showed that treatment of aglycone fraction ($0.05-0.39{\mu}g/mL$) protect human skin cells in a concentration-dependent manner when the skin cell damages were induced by treating them with $H_2O_2$. These results suggest that extract/fractions of G. pentaphyllum Makino may be applicable as natural antioxidants in cosmetics.

Higher Order Structure of 5S rRNA from Xanthomonas palargonii (Xanthomonas palargonii 5S rRNA의 고차원 구조)

  • Cho, Bongrae;Kim, Sang Bumn;Lee, Younghoon;Park, Inwon
    • Journal of the Korean Chemical Society
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    • v.39 no.9
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    • pp.734-740
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    • 1995
  • The primary and secondary structures of Xanthomonas palargonii 5S rRNA were determined. The higher order structure of the 5S rRNA was also analysed using several ribonucleases and chemical probes, such as ethylnitrourea, Pb2+, dimethylsulfate and diethyl pyrocarbonate. Ethylnitrourea was used for probing the phosphate groups involved in the tertiary interactions in the 5S rRNA. Nucleotides G72, A73, G75, A78, G98, G100 and A101 in unstable helical region d, nucleotides C36, C37, A39, and C41 in loop c, nucleotides A29 and G33 in stem C became resistant to ethylnitrourea modification in the presence of Mg2+. On the basis of findings from chemical and enzymatic studies, and also Pb2+-induced cleavages, it was concluded that region b-C and unstable helical region d may act as hinges in the folding of 5S rRNA.

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PAIR OF (GENERALIZED-)DERIVATIONS ON RINGS AND BANACH ALGEBRAS

  • Wei, Feng;Xiao, Zhankui
    • Bulletin of the Korean Mathematical Society
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    • v.46 no.5
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    • pp.857-866
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    • 2009
  • Let n be a fixed positive integer, R be a 2n!-torsion free prime ring and $\mu$, $\nu$ be a pair of generalized derivations on R. If < $\mu^2(x)+\nu(x),\;x^n$ > = 0 for all x $\in$ R, then $\mu$ and $\nu$ are either left multipliers or right multipliers. Let n be a fixed positive integer, R be a noncommutative 2n!-torsion free prime ring with the center $C_R$ and d, g be a pair of derivations on R. If < $d^2(x)+g(x)$, $x^n$ > $\in$ $C_R$ for all x $\in$ R, then d = g = 0. Then we apply these purely algebraic techniques to obtain several range inclusion results of pair of (generalized-)derivations on a Banach algebra.

STABILITY OF HAHN DIFFERENCE EQUATIONS IN BANACH ALGEBRAS

  • Abdelkhaliq, Marwa M.;Hamza, Alaa E.
    • Communications of the Korean Mathematical Society
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    • v.33 no.4
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    • pp.1141-1158
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    • 2018
  • Hahn difference operator $D_{q,{\omega}}$ which is defined by $$D_{q,{\omega}}g(t)=\{{\frac{g(gt+{\omega})-g(t)}{t(g-1)+{\omega}}},{\hfill{20}}\text{if }t{\neq}{\theta}:={\frac{\omega}{1-q}},\\g^{\prime}({\theta}),{\hfill{83}}\text{if }t={\theta}$$ received a lot of interest from many researchers due to its applications in constructing families of orthogonal polynomials and in some approximation problems. In this paper, we investigate sufficient conditions for stability of the abstract linear Hahn difference equations of the form $$D_{q,{\omega}}x(t)=A(t)x(t)+f(t),\;t{\in}I$$, and $$D^2{q,{\omega}}x(t)+A(t)D_{q,{\omega}}x(t)+R(t)x(t)=f(t),\;t{\in}I$$, where $A,R:I{\rightarrow}{\mathbb{X}}$, and $f:I{\rightarrow}{\mathbb{X}}$. Here ${\mathbb{X}}$ is a Banach algebra with a unit element e and I is an interval of ${\mathbb{R}}$ containing ${\theta}$.

Effect of ${\beta}$-Mannanase (CTCZYME$^{(R)}$) on the Growth of Young Calf (${\beta}$-Mannanase (CTCZYME$^{(R)}$) 첨가가 어린 송아지의 성장에 미치는 영향)

  • Lee, Se-Young;Lee, Sang-Moon;Kim, Jong-Hyeong;Ki, Kwang-Seok;Kim, Hyeon-Shup;Kam, Dong-Keun;Lee, Jae-Hwan;Lee, Jung-Jin;Bae, Gui-Seck;Seo, Seong-Won
    • Korean Journal of Agricultural Science
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    • v.37 no.2
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    • pp.239-243
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    • 2010
  • The objective of this study was to evaluate effects of supplementation of ${\beta}$-mannanase (CTCZYME$^{(R)}$, CTCBIO, Inc.) on feed intake, growth performance and fecal health of calves fed two levels (3% vs. 8%) of palm kernel meal (PKM). A total of nine Holstein calves were divided into three groups, and fed a conventional starter containing 3% PKM (CON), CON+0.1% CTCZYME$^{(R)}$ (TRT1), or a starter containing 8% PKM+0.1% CTCZYME$^{(R)}$ (TRT2). No clinical symptom of calves was observed through the trial. We did not find significant differences among the treatments on mean feed intake, growth performance, or fecal health during the four-week experimental period. Feed efficiency tended to be improved by adding CTCZYME$^{(R)}$ (0.46, 0.87 and 0.52 for CON, TRT1 and TRT2, respectively). Compared with CON (921 g/d and 786 g/d), TRT2 had lower feed intake (727 g/d) and average daily gain (ADG, 631 g/d) before weaning. However, feed intake (2300 g/d) and ADG (1012 g/d) were similar or even higher in TRT2 than CON (2269 g/d and 560 g/d) after weaning. This was probably due to the effect of a large amount of mannan-oligosaccharide released from PKM by ${\beta}$-mannanase. Salmonella was not detected any fecal samples. No significant difference was observed in the number of fecal E. coli or fecal properties including color, smell, and watery indexes among the treatments. We conclude that a calf starter containing 8% PKM with 0.1% CTCZYME$^{(R)}$ is comparable with a conventional starter in feed intake and growth performance of calf, which is beneficial in terms of reduction in feed cost.

Development of Printed Bow-tie Antenna with 3 ~ 5 GHz Broadband Characteristics for Testing the Electromagnetic Immunity of Automotive Electrical Components in the 5G Frequency Band (5G 주파수 대역의 자동차 전장품 전자기파 내성 평가를 위한 3 ~ 5 GHz 광대역 특성의 인쇄형 bow-tie 안테나 개발)

  • Ko, Ho-jin;Choi, Beom-jin;Park, Ki-hun;Woo, Jong-myung
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.19 no.3
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    • pp.137-147
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    • 2020
  • This paper proposes printed bow-tie antennas with 3 ~ 5 GHz broadband characteristics were proposed for testing the electromagnetic immunity of automotive electrical components in the 5G frequency band. The antenna get -10 dB bandwidth in the 2.75 ~ 6 GHz frequency band and the broadside radiation pattern with S11 characteristic of -16.2 dB at resonant frequency. In testing electromagnetic immunity in the 5G mobile communication frequency band, the VSWR characteristic remained below 2.1, forming a level of 1 W as proposed by international standards. As a result, it is confirmed that the proposed antenna can be applied to antenna testing for electromagnetic immunity verification in the 5G mobile communication frequency band.

DERIVATIONS ON PRIME AND SEMI-PRIME RINGS

  • Lee, Eun-Hwi;Jung, Yong-Soo;Chang, Ick-Soon
    • Bulletin of the Korean Mathematical Society
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    • v.39 no.3
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    • pp.485-494
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    • 2002
  • In this paper we will show that if there exist derivations D, G on a n!-torsion free semi-prime ring R such that the mapping $D^2+G$ is n-commuting on R, then D and G are both commuting on R. And we shall give the algebraic conditions on a ring that a Jordan derivation is zero.

SOME RELATIONS BETWEEN FUNCTION SPACES ON R$^n$

  • Shin, Seung-Hyun
    • The Pure and Applied Mathematics
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    • v.2 no.1
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    • pp.31-34
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    • 1995
  • Let R$^n$be n-th Euclidean space. Let be the n-th spere embeded as a subspace in R$\^$n+1/ centered at the origin. In this paper, we are going to consider the function space F = {f│f : S$^n$\longrightarrow S$^n$} metrized by as follow D(f,g)=d(f($\chi$), g($\chi$)) where f, g $\in$ F and d is the metric in S$^n$. Finally we want to find certain relation these spaces.(omitted)

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LOCI OF RATIONAL CURVES OF SMALL DEGREE ON THE MODULI SPACE OF VECTOR BUNDLES

  • Choe, In-Song
    • Bulletin of the Korean Mathematical Society
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    • v.48 no.2
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    • pp.377-386
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    • 2011
  • For a smooth algebraic curve C of genus g $\geq$ 4, let $SU_C$(r, d) be the moduli space of semistable bundles of rank r $\geq$ 2 over C with fixed determinant of degree d. When (r,d) = 1, it is known that $SU_C$(r, d) is a smooth Fano variety of Picard number 1, whose rational curves passing through a general point have degree $\geq$ r with respect to the ampl generator of Pic($SU_C$(r, d)). In this paper, we study the locus swept out by the rational curves on $SU_C$(r, d) of degree < r. As a by-product, we present another proof of Torelli theorem on $SU_C$(r, d).

Effects of Temperature on the Pharmacokinetics of Ciprofloxacin in the Cultured Black Rockfish (Sebastes schlegeli) and Olive Flounders (Paralichthys olivaceus)

  • Kim Jin Woo;Jo Mira;Jung Sung Hee;Jee Bo Young;Choi Dong Lim;Jo QTae
    • Fisheries and Aquatic Sciences
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    • v.5 no.3
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    • pp.200-205
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    • 2002
  • Temperature-dependent pharmacokinetics of ciprofloxacin (CIP) was studied in the cultured olive flounders, Paralichthys olivaceus, and black rockfish, Sebastes schlegeli using high performance liquid chromatography (HPLC) originally developed for quinolone determination from livestock. Pharmacokinetics of CIP was apparently affected by ambient water temperature. In a two-compartment model for flounders after oral dosage of 20 mg/kg, $K_{01},\;at\;13^{\circ}C$ and $23^{\circ}C$ were 4.18 and 1.20/hr, respectively. The $K_{10},\;T_{max}\;and\;C_{max}\;at\;13^{\circ}C$ were 5.574/hr, l4.37${\mu}g/mL\;and\;3.15{\mu}g/mL,$ respectively. The corresponding values at $23^{\circ}C$ were l2.84/hr, 15.39${\mu}g/mL\;and\;6.38{\mu}g/mL$, respectively. The AUC, $T_{1/2} (\alpha)\;and\;T_{1/2}\;(\beta)$ were 278.23 ${\mu}g \cdot hr/mL$, 0.24hr and 47.02hr at $13^{\circ}C$ and 3l7.8l${\mu}g \cdot hr/mL$, 0.30 hrs and 60.78hrs at $23^{\circ}C$ for the flounder, respectively. Similar CIP pharmacokinetics were revealed in the black rockfish after oral dosage of 20 mg/kg under the two water temperature regimes. These pharmacokinetical results have some implication in the optimal usage of recently introduced antibacterials in the farmed fish, which were primarily adapted for poultry and mammalian species.