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The Effects of Resistance Exercise on Muscle Function Parameters and Cytokine Concentration in Saliva in Breast Cancer Patients with Sarcopenia

저항성 운동형태가 근감소증 유방암 환자의 근기능 지표 및 타액 내 사이토카인에 미치는 영향

  • Received : 2021.10.19
  • Accepted : 2021.12.20
  • Published : 2021.12.28

Abstract

The purpose of this study was to find out the effects of isomatric and isotonic exercise on the muscle function and cytokine which will prevent recurrence of breast cancer patients. A subjects were thirteen breast cancer patients and they were randomly assigned either isometric exercise group(n=10), isotonic exercises group(n=10) or a daily base care control group(n=10). Resistance exercise group did a exercise program with 60~70%RM for 60min, 3days per week during 8week. There were significantly difference between groups which were showing a increasing flexion, abduction, external rotation, IL-6 and IL-10 in isotonic exercise.

본 연구의 목적은 근감소증이 있는 유방암 환자를 대상으로 서로 다른 근 수축형태의 저항성 운동을 실시하여 상지 근기능 및 타액 내 사이토카인에 미치는 효과를 규명함으로써 유방암 생존자의 재발 방지를 위한 효과적인 운동프로그램의 기초자료를 제공하는데 있다. 근감소증이 있는 유방암 환자(등척성 운동집단 10명, 등장성 운동집단 10명)를 대상으로 8주간 60~70%RM의 강도로 60분 동안 주 3회 실시하였으며, 비교집단(n=10)은 일상생활을 유지하도록 하였다. 8주 운동 전후의 차이를 분석한 결과 어깨관절의 굴곡(p=.001), 외전(p=.001), 외회전(p=.045) 및 사이토카인인 IL-6(p=.000) IL-10(p=.001)의 경우 등장성 운동을 실시하였을 때 더 긍정적인 효과가 있었다.

Keywords

Acknowledgement

This work was supported by the Ministry of Education of the Republic of Korea and the National Research Foundation of Korea (NRF-2019S1A5B5A07104261).

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