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  • Title/Summary/Keyword: triglyceride.

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Immunopotentiating Effect of Polysaccharide Produced from a Mutant of Acetobacter pasteurianus (I) (Acetobacter pasteurianus 변이주가 생산하는 다당류의 면역효과(I))

  • 김동석;정연봉조덕제류병호
    • KSBB Journal
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    • v.7 no.1
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    • pp.39-44
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    • 1992
  • Dose-dependent responses indicated by the increase of leukocyte, peritoneal exudate cell and weights of immunorgans revealed the improvement of immunity. In the effect of macrophage on phagocytes, there were not substantial differences in the phagocytic and corrected phagocytic index. The administered group being compared with the controlled group, there were no significant changes in SGOT, S-GPT, alaline phosphatase, total protein, albumin, globulin, cholesterol, triglyceride, blood urea nitrogen and glucose. Key words: dose-dependent responses, peritoneal exudate cell, phagocytic idex, corrected phagocytic index.

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Effects of Coptidis Rhizoma on Lowering Lipid and Oxidative Stress

  • Lee, Eun;Cho, Eun-Joo
    • Korean Journal of Plant Resources
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    • v.20 no.6
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    • pp.544-547
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    • 2007
  • The effects of hwangryun(Coptidis Rhizoma) on lowering lipid and oxidative stress in the induced obesity rat was observed. The concentration of plasma triglyceride in hwangryun treatment groups showed the low values compared to the control group, and as the increased hwangryun, the concentration of triglyceride decreased. The concentration of plasma total cholesterol decreased in all hwangryun treatment groups. However the concentration of plasma HDL-cholesterol and LDL-cholesterol showed no significantly difference in all the treatment groups. Thiobarbituric acid reactive substance(TBARS) concentration in plasma and liver showed low values in all hwangryun treatment groups compared to the control group. Glutathione peroxidase(GSH-Px) and superoxide dismutase(SOD) activities showed no significantly difference in all the treatment groups. However catalase(CAT) activity showed a tendence to increase in hwangryun groups, and in 200mg/kg hwangryun treatment group showed significantly a high value than the control group. Summarizing the results above, hwangryun has the functional materials that lowering lipid and works with oxidative stress.

The Preventive Effect of Fursulthiamine on Dietary Hypertension in Rats (Fursulthiamine이 흰쥐의 식이성 고혈압에 대한 예방효과)

  • 이은방;이영순;김옥경
    • YAKHAK HOEJI
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    • v.43 no.1
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    • pp.91-97
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    • 1999
  • Dietary hypertension induced by feeding cholesterol and vitamin D3 in rats for 7 weeks was prevented by the addition of fursulthiamine and diallyl disulfide in the diet. In the isolated preparation of the hypertentive rats, the contractile forces were potentiated by norepinephrine, serotonin and potassium chloride, as compared to that of the normotensive rats. However, the increased contractile forces of the hypertensive rats were inhibited in the aorta of the rats fed with fursulthiamine. Decreases in triglyceride contents were observed in the sera of the hypertensive rats fed with fursulthiamine. Therefore, it is suggested that dietary hypertension in rats may be prevented by supplement of fursulthiamine in the diet.

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Effect of Bread Added with Silkpeptide and Cholesterol on Lipid Metabolism of Rat (실크펩티드를 첨가한 빵이 Rat의 지질대사에 미치는 영향)

  • Kim, Young-Ho;Cho, Nam-Ji
    • Journal of the East Asian Society of Dietary Life
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    • v.17 no.2
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    • pp.198-204
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    • 2007
  • The aim of this study was to investigate the effect of bread supplemented with silkpeptide and cholesterol of on the lipid metabolism in rats. When a rats were fed bread supplemented with silkpeptide and cholesterol, their net weight tended to decrease compared with the control. Although the food intake was increased, this was not significant., but the feed efficiency ratio was substantially decreased. The total and LDL-cholesterols were decreased, but the DHL-cholesterol was increased. The HDL-cholesterol to total cholesterol ratio and level of triglyceride were substantially increased. The atherogenic index was decreased when rats are fed bread supplemented with silkpeptide and; thus, would show an improvement in the effect of high-cholesterol symptoms.

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Effects of Sulfur-Containing Amino Acids on Lipid Metabolism in Rats (함유황아미노산이 지질대사에 미치는 영향)

  • 박정로;최성희
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.24 no.6
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    • pp.978-983
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    • 1995
  • The effect of sulfur-containing amino acids on lipid metabolism was studied in rats fed casein as a protein source. Plasma cholesterol, HDL-cholesterol and atherosclerotic index decreased in the cysteine group compared to the methionine group. Plasma triglyceride and phospholipid level were not affected by the supplementation of the sulfur-containing amino acids. The levels of cholesterol and triglyceride in liver decreased by both methionine and cysteine. Cysteine increased the fecal excretion of coprostanol, total neutral steroid and bile acid. The results suggest that plasma cholesterol level is affected by dietary ratio of cysteine/methionine and that the hypocholesterolemic effects of cysteine is, at least in part, through reducing cholesterol absorption from small intestine and through enhancing fecal excretion of bile acids.

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EFFECTS OF PERSICAESEMEN ON THE HYPERLIPIDEMIA RATS INDUCED BY TRITON WR-1339 (도인(桃仁)이 Triton WR-1339로 유발(誘發)된 흰쥐의 고지혈증(高脂血症)에 미치는 영향(影響))

  • Yun Wang-Su;Soh Kyung-Sun;Jeong Chan-Gil
    • Journal of Society of Preventive Korean Medicine
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    • v.6 no.2
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    • pp.128-136
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    • 2002
  • In order to study effects of PersicaeSemen on the hyperlipidemia rats induced by Triton WR, we have made hyperlipidemia rats by administering Triton WR-1339 for 3 days, then have administered. The results were summerized as follows: 1. The total cholesterol, triglyceride and phospholipid by hypercholesteremic rats injected by Triton WR-1339 of the sample group were decreased as compared with those of the control group, 2. The HDL-cholesterol by hypercholesteremic rats injected by Trion WR -1339 were increased as compeared those of control group. According to the above results, Persicae Semen showed inhibition on increase of serum total cholesterol, triglyceride and phosholipid contents as well as inhibition on decrease of HDL-cholesterol contents in hyperlipidemia.

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Experimental study on the effects of Luffae fasciculus vascularis(絲瓜絡) on hyperlipidemia (사과락(絲瓜絡)이 Triton Wr 투여로 유발되는 고지혈증(高脂血證) 예방에 미치는 영향에 대한 실험적 연구)

  • Lee Jeong-Seok;Soh Kyung-Sun;Jeong Chan-Gil
    • Journal of Society of Preventive Korean Medicine
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    • v.6 no.2
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    • pp.95-103
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    • 2002
  • In order to study the effect of Luffae fasciculus vascularis(絲瓜絡) on hyperlipidemia, experimental study was performed on Hyperlipidemia induced by Triton WR-1339. Also the level of Total cholesterol, Triglyceride, HDL-cholesterol, Phospholipid and LDL-cholesterol were measured. The results are summarized as follow: In the model of hyperlipidemia Rats induced by Triton WR-1339, luffae fasciculus vascularis(絲瓜絡) had significantly decreasing effects on total cholesterol, triglyceride, phospholipid, LDL-cholesterol in serum and increasing effects on HDL-cholesterol level in serum but were not significant. These results show that Luffae fasciculus vascularis(絲瓜絡) has significantly inhibitory effects on hyperlipidemia and that it could be clinically applied for hyperlipidemia.

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Protective Effect of Sachungwhan against CCl4-induced Hepatotoxicity

  • Koo, Ja-Young;Jung, Ki-Hwa
    • Biomolecules & Therapeutics
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    • v.14 no.4
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    • pp.207-215
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    • 2006
  • Sachungwhan reduced hepatotoxicity induced by carbon tetrachloride(CCl4). Improved liver function was observed by measuring the activities of aspartate aminotransferase(AST), alanine aminotransferase(ALT), alkaline phosphatase(ALP), blood urea nitrogen(BUN), creatinine(CRE), total cholesterol(TCHO), triglyceride(TG), low density lipoprotein cholesterol(LDL-CHO), high density lipoprotein cholesterol(HDL-CHO), total protein(TP), albumin(ALB) and total bilirubin(BIL) in serum. Hepatic parameters monitored were levels of cholesterol(CHO), triglyceride(TG), malondialdehyde(MDA), content of cytochrome P450(CYP), level of glutathione(GSH), and activities of NADPH-CYP reductase, superoxide dismutase(SOD), catalase(CAT), glutathione S-transferase(GST), glutathione reductase(GR), glutathione peroxidase(GPx). The histopathological examination showed that the treatment of Sachungwhan relieved the ballooning degeneration of hepatocytes which had been generated by CCl4. The results suggested that hepatoprotective effects of Sachungwhan possibly are due to their promising antioxidative activity.

Effect of Artemisia Princeps var Orientalis and Circium Japonicum var Ussuriense on Liver Function, Body Lipid , and Bile Acid of Hyperlipidemic Rat (쑥 및 엉겅퀴가 식이성 고지혈증 흰쥐의 간기능, 체지질 및 담즙산 농도에 미치는 영향)

  • 임상선
    • Journal of Nutrition and Health
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    • v.30 no.7
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    • pp.797-802
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    • 1997
  • The effect of Artemisia princeps var orientalis(mugwort) and Circium japonicum var ussuriense (Unggungqui) on lipid metabolism was examined . Thirty rats of 5 experimental groups were fed with a diet containing 1% cholesterol and 0.25% sodium cholate(control diet) and 5% plant powder or its water soluble extract(experimental diet) for 4 weeks. The activity of enzymes related to liver function, lipid components of liver and principle organs, and fecal steroids were assayed. The activity of enzymes was significantly lower in the unggungqui and mugwort powder diet group than in control. Liver total cholesterol , free cholesterol, and triglyceride levels were significantly lower in Unggungqui powder diet groups that in the control. The concentrations of total cholesterol , triglyceride and phospholipid in heart and kidney were comparatively low in the Unggungqui powder diet groups. In each plant powder diet group, the values of serum bile acid were significantly lowe ran the fecal steroid excretion was higher than in the control and the extract diet groups.

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Effectsof Garlic Vinegar Supplementation on Changes of Body Weight, Plasma Glucose, and Plasma Lipid Profile in High Cholesterol-fed Rats

  • Choi, Mi-Ja;Cho, Hyun-Ju;Choi, Myung-Sook;Choi, Yong-Hee
    • Preventive Nutrition and Food Science
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    • v.4 no.3
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    • pp.197-199
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    • 1999
  • This study was carried out to investigate the effects of garlic vinegar supplementation on changes in body weight, blood glucose and serum triglyceride and cholesterol. Rats were fed a cholesterol-diet with or without garlic vinegar (20% garlic juice )supplement for 28days. Body weights in rats fed a diet containing garlic vinegar were significantly lower than those of control rats. The concentration of plasma glucose, total cholesterol . LDL-cholesterol , and HDL-cholesterol were not significantly different between the two groups for a period of up to four weeks. However, the concentration of plasma triglyceride was slightly decreased in the garlic vinegar-supplemented group. Results suggest that the supplementation of garlic vinegar is beneficial for weight reduction in high-cholesterol fed rats.

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