• Journal of Nutrition and Health
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• 제21권5호
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• pp.324-332
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• 1988

Effects of a change in dietary Ca content and an alteration in dietary lipid type on lipid metabolism have been investigated in male Sprague-Dawley rats. The results obtained were summarized as follows ; 1) There was no comparable changes in food consumption and body weight gain among all 9 groups. 2) Serum total lipids and cholesterol were lowest when high Ca-corn all diet was fed, and highest when low Ca-butter diet was fed. 3) The contents of total lipids and cholesterol per g liver and total liver showed no consistent tendency with the dietary treatment. 4) Addition of Ca to the diet caused the significant increase in the dry fecal matter and fecal Ca. And fecal total lipids and fecal cholesterol were much greater if the high-Ca diet was fed than if control and low-Ca diet were fed. It is concluded that Ca and polyunsaturated acids have tendency of hypocholesterolemic effect.

• Asian-Australasian Journal of Animal Sciences
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• 제12권2호
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• pp.192-196
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• 1999

The purpose of this experiment was to study the effects of feeding egg yolk prepared from quail fed winged bean oil on plasma and liver cholesterol and fatty acids composition in rats. Eggs were collected from laying quails that had been fed diets containing 5% of either animal tallow, soybean oil, corn oil or winged bean oil. Yolk powders (referred to as winged bean yolk, soybean yolk, etc.) were prepared and fed at the 15% level to weanling female Wistar rats for 28 days. Rats fed winged bean yolk had significantly lower body weight gain than did rats fed soybean yolk or animal tallow yolk. There are no significant effects on plasma total cholesterol, liver cholesterol and triglyceride concentration due to feeding yolk powder containing different oil. However, LDL-cholesterol increased and HDL-cholesterol decreased in rats fed winged bean yolk. Liver lipid of rats fed with winged bean yolk had a higher linoleic but a lower linolenic content than did those fed animal tallow yolk. However, rats fed with winged bean yolk had a lower linoleic content than did rats fed soybean yolk or corn yolk. In conclusion, winged bean yolk seemed to have had an adverse effect on rats.

• 한국축산식품학회지
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• 제35권4호
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• pp.479-485
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• 2015

This experiment investigated whether yogurt containing fermented pepper juice (FPJY) affects cholesterol level in high fat and high cholesterol diet (HFCD) fed rat. Twenty five Sprague-Dawley male rats of 7 wk were divided into 5 groups, and fed following diets for 9 wk; CON (control diet), HFCD (HFCD), PY (HFCD supplemented with 2% of plain yogurt), LFY (HFCD supplemented with 2% of FPJY), and HFY (HFCD supplemented with 5% of FPJY). In the LFY group, hepatic total lipid level decreased significantly compared to the HFCD group (p<0.05). Serum HDL cholesterol level tended to increase and hepatic total cholesterol level decreased and were comparable to the CON group (p>0.05). In HFY group, body weight and hepatic total lipid level significantly decreased over the HFCD group (p<0.05). Serum and hepatic total cholesterol level, kidney, and body fat weights decreased, and were compared to the CON group (p>0.05). Liver weight decreased as FPJY content was increased. Results suggested FPJY would inhibit organ hypertrophy and accumulation of body fat, hepatic lipid, and cholesterol in HFCD fed rat.

• 생약학회지
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• 제37권4호
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• pp.324-330
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• 2006

The aim of this study was to evaluate the effects of Artemisia Princeps Var. Orientalis (AP) on serum lipids and the collagen content of the connective tissues in ovariectomized rats. From day 2 until day 37 after the ovariectomy, Sprague-Dawley female rats were randomly assigned to the following groups: sham-operated rats (Sham), ovariectomized control rats (OVX-control), and ovariectomized rats supplemented with the AP 50 mg/kg bw/day (OVX-AP). The AP ethanol extracts were orally administrated 1 mL per day. The OVX rats were significantly heavier than the sham-operated rats at all time points, but supplementation with the AP extracts tended to gain weight less than OVX-control. Although total-cholesterol was increased at OVX-control, supplementation with the AP extracts tended to result in less than OVX-control. Triglyceride was significantly decreased after supplemented with the AP extracts (p<0.05). HDL-cholesterol is appeared higher AP extracts group than OVX-control. According to the results, we could know the fact that AP extracts were effective on serum lipids content throughout decreasing total-cholesterol, triglyceride and increasing HDL-cholesterol in ovariectomized rats. Supplementation with the AP extracts prevented a decrease in the collagen level in bone and cartilage tissues. These results are consistent with the conclusions based on the estrogenic activities of AP. Therefore, it may be used to possibly improve the quality of life in menopausal women.

• 한국응용과학기술학회지
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• 제22권2호
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• pp.157-167
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• 2005

The extraction yield of Corni fructus was about 47.5% by extract apparatus. This study was done to investigate the antidiabetic and antioxidative effects of Corni fructus in Streptozotocin (STZ)-induced diabetic rats. The contents of serum glucose, total cholesterol and hepatic lipid peroxide, glutathione were significantly decreaed (p<0.05) in Corni fructus treated group compared to the those of STZ-control group, also content of triglyceride (TG), atherogenic index (AI) and activity of catalase were decreased, but not statistically significant. High density lipoprotein (HDL)-cholesterol and HDL-cholesterol/total cholesterol ratio (HTR) were increased in Corni fructus treated group compared to the those of STZ-control group. The activities of glutathione-S-transferase (GST) and superoxide dismutase (SOD) were significantly decreaed (p<0.05) in Corni fructus treated group compared to the those of STZ-control group. The content of hepatic glycogen and activities of glucose-phosphate dehydrogenase (G-6 PDH), glucokin-ase were significantly increased, but activity of glucose-Grphosphatase (G-6 Pase)was decreased in Corni fructus treated group compared to the those of STZ-control group. Therefore, these results indicated that ethanol extract of Corni fructus would have antidiabetic and antioxidative effects in STZ-induced diabetic rats.

• 한국응용과학기술학회지
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• 제25권1호
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• pp.73-82
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• 2008

This study was done to investigate the antidiabetic and antioxidant effects of Lycii fructus in Streptozotocin (STZ)-induced diabetic rats. Diabetes was induced by intravenous injection of STZ at a dose 45mg/kg.b.w. dissolved in citrate buffer(pH4.5). The ethanol extract of Lycii fructus was orally administrated once a day for 7 days. The contents of serum glucose, total cholesterol were significantly decreaed (p<0.05) in Lycii fructus treated group compared to the those of STZ-control group, also content of Triglyceride (TG), Altherogenic index (AI) were decreased, but not statistically significant. But high density lipoprotein (HDL)-cholesterol and HDL-cholesterol/total cholesterol ratio (HTR) were increased in Lycii fructus treated group compared to the those of STZ-control group. The content of hepatic glycogen and activities of glucose-6-phosphate dehydrogenase(G-6PDH), glutathione-s-transferase(GST), superoxide dismutase(SOD) were significantly increased(p<0.05), glucose-6-phos-phatase(G-6pase)was significantly decreased(p<0.05) and The glutathione(GSH), glucokinase(GK) were increased. But not statistically significant In Lycii fructus treated group compared to the those of STZ-control group These results indicated that ethanol extract of Lycii fructus would have antidiabetic and antioxidant effects in STZ-induced diabetic rats.

• Journal of Nutrition and Health
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• 제11권1호
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• pp.27-32
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• 1978

The purpose of this survey was to determine crude fat, crude protein, phospholipid, and total Cholesterol contents of Seolnong-Tang and Other 11 Samples which are traditional diet in Korea, The results obtained were summarized as folllows; 1) The content of crude protein was $7.34{\pm}1.08%$ in Chueo-Tang to $2.94{\pm}0.08%$ in Sundae-Gug, and the content of crude fat was $7.20{\pm}0.31%$ in Seonji-Gug to $2.64{\pm}0.31%$ in Jog-Tang 2) Triglyceride Content of fat was the highest value in Seolnong-Tang ($89.09{\pm}1.34%$) and the lowest one Samgae-Tang ($75.29{\pm}0.37%$). 3) Phospolipid content of fat showed the highest group in Yuqqae-Jang ($12.39{\pm}0.28%$) and Seonji-Gug ($12.18{\pm}0.31%$) the lowest group was Seolnong-Tang ($4.88{\pm}0.73%$) and Dogani-Tang ($4091{\pm}0.30%$). 4) In total cholesterol content of fat extracted, Bosin-fang ($1732.28{\pm}80.85mg%$) was the highest value and Dogani-Tang ($570.66{\pm}22.04mg%$) showed the lowest. 5) In total cholesterol contents of one diet, the highest group was Seonji-Gug ($667.40{\pm}35.73mg$) and Bosin-Tang ($652.96{\pm}22.27mg$) the lowest group was Jog-Tang ($147.64{\pm}17.33mg$) Daggom-Tang ($174.32{\pm}16.63mg$) and Dogani-Tang ($176.36{\pm}19.13mg$).

• 한국식품저장유통학회지
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• 제20권2호
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• pp.278-283
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• 2013

법제화된 유황이 육계사육에 미치는 영향을 알아보고자 유황사료를 급여한 닭의 폐사율, 무게 증가량을 측정 하였으며, 혈액의 항산화 활성과 혈액 내 글루타치온 및 콜레스테롤 함량, 그리고 계육의 단백질, 지방 분석과 닭유래 세포에서의 법제유황의 세포독성을 알아보았다. 먼저 일반사료에 비해 유황사료를 급여한 닭의 경우 폐사율이 감소하며, 닭의 무게가 증가하는 것을 알 수 있었다. 혈액 내 항산화활성을 FRAP 측정법을 이용하여 확인 한 결과 일반사료 급여군에 비해 유황사료 급여군에서 항산화 활성이 증가하였다. 혈액 내 전체 콜레스테롤 함량에는 큰 차이가 나지 않지만, 고밀도 콜레스테롤은 증가하는 반면, 저밀도 콜레스테롤은 감소하는 것을 확인하였다. 또한 계육에서의 총 아미노산과 단백질 함량은 변화가 없지만 지방 함량은 크게 감소시키는 것을 알 수 있었으므로 유황사료가 계육의 품질을 향상시켜 상품성을 높여줄 수 있을 것으로 사료되었다

• 한국식품과학회지
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• 제35권2호
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• pp.280-285
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• 2003

본 연구에서는 streptozotocin-유도 당뇨쥐를 이용하여 배양인삼의 첨가식이가 혈당강하 및 지질대사 등에 미치는 영향을 조사하기 위해 대조군과 당뇨대조군, 5% 및 10% 배야인삼첨가군 등 모두 4군으로 나누어 해당식이로 2주간 사육하였다. 배양인삼은 당뇨쥐의 체중증가와 혈당저하에 효과를 나타냈으며, 수분 및 사료 섭취량도 줄여 당뇨병 증세의 개선효과를 보였다. 또한 당뇨쥐의 지질대사를 개선하여 혈장중성지방, 총 콜레스테롤 및 동맥경화지수를 저하시키고 총 콜레스테롤에 대한 HDL-콜레스테롤의 비율을 증가시켰다. AST 및 ALT의 활성은 5% 첨가군에서만 당뇨대조군에 비해 낮은 값을 보였으며, 10% 첨가군에서는 오히려 높은 값을 보였다. Creatinine의 함량은 모든 첨가군에서 당뇨대조군에 비해 현저히 낮은 값을 보였다.

• Journal of Nutrition and Health
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• 제31권8호
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• pp.1217-1225
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• 1998

This study was conducted to investigate the effects of shellfish on lipid metabolism in rats fed high fat supplements. Male sprague-dawley rats weighting approximately 165g were fed a basal diet, a high fat diet, or a high fat diet plus shellfish for 4 weeks. The shellfishes on the were oyster, hard-shelled mussel, little neck clam, and march clam. Alfter 4 weeks high fat diet, supplementation of 20% lard significantly increased plasma. GOT, GPT, ${\gamma}$-GTP , and liver triglyceride (TG). Plasma GOT, GPT, ${\gamma}$-GTP , triglyceride, and total cholestrerol levels were significantly lower in shellfish groups than in basal and high-fat groups regardless of high-fat supplementation (p<0.05). The total lipid and cholesterol content in liver showed similar results(p<0.05). There were no differences in glucose, HDL-cholesterol in plasma and total cholesterol and total lipid in liver between basal and high-fat supplemented diets. Liong chain fatty acids, specific components of shellfishes group, were exclusively higher than in basal and high-fat diets, and were most well-reflected in liver and plasma. From the above results, the hypolipidemic effects of shellfish were detected in the process of inducing hyperlipidemia by high-fat supplement.