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http://dx.doi.org/10.5851/kosfa.2015.35.4.479

Effects of Yogurt Containing Fermented Pepper Juice on the Body Fat and Cholesterol Level in High Fat and High Cholesterol Diet Fed Rat  

Yeon, Su-Jung (Department of Food Science and Biotechnology of Animal Resources, Konkuk University)
Hong, Go-Eun (Department of Food Science and Biotechnology of Animal Resources, Konkuk University)
Kim, Chang-Kyu (Department of Animal Science and Biotechnology, Sangji University)
Park, Woo Joon (Department of Food Science and Biotechnology of Animal Resources, Konkuk University)
Kim, Soo-Ki (Department of Animal Science and Technology, Konkuk University)
Lee, Chi-Ho (Department of Food Science and Biotechnology of Animal Resources, Konkuk University)
Publication Information
Food Science of Animal Resources / v.35, no.4, 2015 , pp. 479-485 More about this Journal
Abstract
This experiment investigated whether yogurt containing fermented pepper juice (FPJY) affects cholesterol level in high fat and high cholesterol diet (HFCD) fed rat. Twenty five Sprague-Dawley male rats of 7 wk were divided into 5 groups, and fed following diets for 9 wk; CON (control diet), HFCD (HFCD), PY (HFCD supplemented with 2% of plain yogurt), LFY (HFCD supplemented with 2% of FPJY), and HFY (HFCD supplemented with 5% of FPJY). In the LFY group, hepatic total lipid level decreased significantly compared to the HFCD group (p<0.05). Serum HDL cholesterol level tended to increase and hepatic total cholesterol level decreased and were comparable to the CON group (p>0.05). In HFY group, body weight and hepatic total lipid level significantly decreased over the HFCD group (p<0.05). Serum and hepatic total cholesterol level, kidney, and body fat weights decreased, and were compared to the CON group (p>0.05). Liver weight decreased as FPJY content was increased. Results suggested FPJY would inhibit organ hypertrophy and accumulation of body fat, hepatic lipid, and cholesterol in HFCD fed rat.
Keywords
fermented pepper juice; yogurt; high fat and high cholesterol diet; Bacillus licheniformis; body fat accumulation;
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1 Shin, K. O. and Moritani, T. (2007) Alterations of autonomic nervous activity and energy metabolism by capsaicin ingestion during aerobic exercise in healthy men. J. Nutr. Sci. Vitaminol. Tokyo 53, 124-132.   DOI
2 Srinivasan, M. R. and Satyanarayana, M. N. (1987) Influence of capsaicin, curcumin and ferulic acid in rats fed high fat diets. J. Biosci. 12, 143-152.   DOI
3 Kawada, T. and Iwai, K. (1985) In vivo and in vitro metabolism of dihydrocapsaicn, a pungent principle of hot pepper in rats. Agric. Biol. Chem. 49, 441-448.   DOI
4 Tang, Z., Ma, J., Zeng, Z., Wu, S., and Hou, M. (2014) Inhibition of atherosclerotic plaque formation in ApoE-deficient mice by dietary supplementation with Lactobacillus casei. Funct. Food Health Dis. 4, 147-158.
5 Tani, Y., Fujioka, T., Sumioka, M., Furuichi, Y., Hamada, H. and Watanabe, T. (2004) Effects of capsinoid on serum and liver lipids in hyperlipidemic rats. J. Nutr. Sci. Vitaminol. 50, 351-355.   DOI
6 Kapila, S. and Vibha, P. R. S. (2006) Antioxidative and hypocholesterolemic effect of Lactobacillus casei ssp casei (biodefensive properties of lactobacilli). Indian J. Med. Sci. 60, 361-370.   DOI
7 Kim, A. R., Lee, J. J., Lee, Y. M., Jung, H. O., and Lee, M. Y. (2010) Cholesterol-lowering and anti-obesity effects of Polymnia Sonchifolia Poepp. & Endl. powder in rats fed a high fat-high cholesterol diet. J. Korean Soc. Food Sci. Nutr. 39, 210-218.   DOI
8 Kim, S. K., Cho, S. B., Kim, S. O., Won, M. Y., Lee, C. H., and Moon, H. I. (2011) Isolation of capsaicin degrading bacteria and its cleavage. Proceed. 7th Asian Pacific Conference on Clinical Nutrition. Bangkok, Thailand, pp. 1198.
9 Lee, S. M., Kim, S. Y., Lee, J. S., Yu, K. W., Chang, I. S., and Suh, H. J. (2008) Nonpungent capsicum fermentation by Bacillus subtilis and the addition of rapidase. Appl. Microbiol. Biotechnol. 81, 257-262.   DOI
10 Luo, X. J., Peng, J., and Li, Y. J. (2011) Recent advances in the study on capsaicinoids and capsinoids. Eur. J. Pharmacol. 650, 1-7.   DOI
11 Iwai, K. and Watanabe, T. (1999) Tougarashi-shinnminokagaku. Saiwaishobo, Tokyo, pp. 39.
12 Chen, L., Hwang, J. E., Choi, B. R., Gu, K. M., Park, Y. M., and Kang, Y. H. (2014) Antioxidant capacities and cytostatic effect of Korean red pepper (Capsicum annuum L): A screening and in vitro study. J. Korean Soc. Appl. Biol. Chem. 57, 43-52.   DOI
13 Iwasaki, Y., Tamura, Y., Inayoshi, K., Narukawa, M., Kobata, K., Chiba, H., Muraki, E., Tsunoda, N., and Watanabe, T. (2011) TRPV1 agonist monoacylglycerol increases UCP1 content in brown adipose tissue and suppresses accumulation of visceral fat in mice fed a high-fat and high-sucrose diet. Biosci. Biotechnol. Biochem. 75, 904-909.   DOI
14 Anderson, J. W. and Gilliland, S. E. (1999) Effect of fermented milk (yogurt) containing Lactobacillus acidophilus L1 on serum cholesterol in hypercholesterolemic humans. J. Am. Coll. Nutr. 18, 43-50.   DOI
15 Chatterjee, S., Asakura, M., Chowdhury, N., Neogi, S. B., Sugimoto, N., Haldar, S., Awasthi, S. P., Hinenoya, A., Aoki, S., and Yamasaki, S. (2010) Capsaicin, a potential inhibitor of cholera toxin production in Vibro cholera. FEMS Microbiol. Lett. 306, 54-60.   DOI
16 Cho, S. B., Moon, H. I., Hong, G. E., Lee, C. H., Kim, J. M., and Kim, S. K. (2014) Biodegradation of capsaicin by Bacillus licheniformis SK1230. J. Korean Soc. Appl. Biol. Chem. 57, 335-339.   DOI
17 Gerner, P., Binshtok, A. M., Wang, C. F., Hevelone, N. D., Bean, B. P., Woolf, C. J, and Wang, G. K. (2008) Capsaicin combined with local anesthetics preferentially prolongs sensory/nociceptive block in rat sciatic nerve. Anesthesiol. 109, 872-878.   DOI
18 Dou, D., Ahmad, A., Yang, H. J., and Sarkar, F. H. (2011) Tumor cell growth inhibition is correlated with levels of capsaicin present in hot peppers. Nutr. Cancer 63, 272-281.   DOI
19 Flagan, S. F. and Leadbetter, J. R. (2006) Utilization of capsaicin and vanillylamine as growth substrates by Capsicum (hot pepper)-associated bacteria. Environ. Microbiol. 8, 560-565.   DOI
20 Folch, J., Lees, M., and Sloane Stanley, G. H. (1956) A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226, 497-509.
21 Akalin, A. S., Gonc, S., and Duzel, S. (1997) Influence of yogurt and acidophilus yogurt on serum cholesterol levels in mice. J. Dairy Sci. 80, 2721-2725.   DOI
22 Akiyama, T., Tachibana, I., Shirohara, H., Watanabe, N., and Otsuki, M. (1996) High-fat hypercaloric diet induces obesity, glucose intolerance and hyperlipidemia in normal adult male Wistar rat. Diabetes Res. Clin. Pr. 31, 27-35.   DOI
23 Odamaki, T., Xiao, J. Z., Yonezawa, S., Yaeshima, T., and Iwatsuki, K. (2011) Improved viability of bifidobacteria in fermented milk by cocultivation with Lactococcus lactis subspecies lactis. J. Dairy Sci. 94, 1112-1121.   DOI
24 Tessari, P., Coracina, A., Cosma, A., and Tiengo, A. (2009) Hepatic lipid metabolism and non-alcoholic fatty liver disease. Nutr. Metab. Cardiovas. Dis. 19, 291-302.   DOI
25 Wardlaw, G. M., Hampl, J. S., and DiSilvestro, R. A. (2005) Perspectives in Nutrition. Lifescience, Seoul, pp. 34.
26 Wirth-Dzięciołowska, E., Karaszewska, J., Sadowski T., Pyśniak, K., and Gajewska M. (2009) Selected blood serum biochemical indicators in twelve inbred strains of laboratory mice. Anim. Sci. Pap. Rep. 27, 159-167.
27 Xiao, J. Z., Kondo, S., Takahashi, N., Miyaji, K., Oshida, K., Hiramatsu, A., Iwatsuki, K., Kokubo, S., and Hosono, A. (2003) Effects of milk products fermented by Bifidobacterium longum on blood lipids in rats and healthy adult male volunteers. J. Dairy Sci. 86, 2452-2461.   DOI
28 Yeon, S. J., Kim, S. K., Kim, J. M., Lee, S. K., and Lee, C. H. (2013) Effect of fermented pepper powder on body fat accumulation in mice fed a high-fat diet. Biosci. Biotechnol. Biochem. 77, 2294-2297.   DOI
29 Pereira, D. I. A., MeCartney, A. L., and Gibson, G. R. (2003) An in vitro study of the probiotic potential of a Bile-Salt-Hydrolyzing Lactobacillus fermentum strain, and determination of its cholesterol-lowering properties. Appl. Environ. Microb. 69, 4743-4752.   DOI
30 Rappaport, A. M. (1993) Diseases of the liver. In: Physioan-atomic consideration. 7th ed, Schiff L, Schiff ER, JB Lippincott Co., Philadelphia. pp. 18-22.
31 Reinbach, H. C., Smeets, A., Martinussen, T., Moller, P., and Westerterp-Plantenga, M. S. (2009) Effects of capsaicin, green tea and CH-19 sweet pepper on appetite and energy intake in humans in negative and positive energy balance. Clin. Nutr. 28, 260-265.   DOI