• Journal of Pharmaceutical Investigation
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• 제3권4호
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• pp.5-15
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• 1973

An investigation was carried out on a basis of the bacteriological examination with a view to detecting the degree of bacterial contamination for the 77 samples collected from the locally-sold liquid specialties. It's test period was 50 days from July 10 to August 30, 1971. Specially, the survey has put emphasis on the population of general bacteria and the identification of coli-form group, staphylococcus species, streptococcus species, bacillus species, fungi, and yeast species from liquid samples. The results obtained are summarized as follows; (1) For the 77 samples tested, the contamination of general bacteria was found out as minimun 0, i,e., maximum, $12{\times}10^4$ and the total average $45{\times}10^2$ per milliliter. (2) Although streptococcus species could not be detected with the samples, the contamination of the coli-form and staphylococcus species means the strong suggestion of the possibility of pathogenic bacterial contamination. (3) Specially, the products which stay in the neutral pH range and use suspending agents need to care for the microbial contamination in the manufacturing crocess. (4) It is thought necessary to perform the microbiological quality control in the liquid preparations only at least. (5) As the microbial contamination degree in the liquid decreases according to the elapse of time, the microbiological quality control will have to be carried out immediately after the completion of the manufacturing process in order to know the accurate degree. (6) The author thinks that the main reason of the microbial contamination in the liquid is the contamination during the manufacturing process. (7) For the purpose of prevention of the microbial contamination in liquid, therefore, it is more important to make efforts for the rationalization of manufacturing process, the improvement of equipment and environment, the specific training of workers for hygienic knowledges, etc. rather than the use of preservatives for the preparations.

• 한국조경학회지
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• 제35권5호
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• pp.16-28
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• 2007

In this study, the implications for landscape architecture in the restoration Project of Cheonggyecheon will be shown through the analysis of factors for landscape architect scheme modification. The method of study consists of theoretical study, analysis of the plan and design of landscape architecture of the restoration project of Cheonggyecheon, and deduction of implications thereof. The controversial feints included the many difficulties in realizing the productive design of landscape architecture due to the selective collecting of public opinion and the problems of settling the complications, the design limit of the turnkey and MA systems, the lack of hydraulic knowledge and technology and the shortage of vegetation monitoring data and experimental materials. The alternative proposals are as follows: 1) there should be agreement between the government organization and the civil group, 2) in the turnkey bidding for the river restoration projects, the river restoration design based on the volume divided into some parts should be reconsidered in order to maintain consistency in the total design, 3) in order to maintain consistency in the planning policies, MA designs should also be introduced and applied from the first stage of the project through its completion, and 4) data such as the safe water level in case of flooding for the facilities and the vegetation and data in connection with the ecological restoration of river should be accumulated. If these controversies are not settled effectively, the river restoration project will be delayed due to complications with the citizens and wasted time and effort will result from the frequent design changes. In addition, landscape architecture in this kind of restoration project is bound to decrease in the future due to frequent changes in the hydraulic-centered design.

• 한국농공학회논문집
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• 제57권4호
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• pp.73-84
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• 2015

An embankment raising project on 113 agricultural reservoirs in Korea was implemented in 2009 to increase water supply capacity for agricultural water and instream uses. This study evaluated the future water supply capacity of the Imgo reservoir at which the agricultural reservoir embankment raising project was completed, considering climate change scenarios. The height of the embankment of the reservoir was increased by 4.5 m, thereby increasing its total storage from 1,657.0 thousand to 3,179.5 thousand cubic meters. To simulate the reservoir water storage with respect to climate changes, two climate change scenarios, namely, RCP 4.5 and RCP 8.5 (in which greenhouse gas reduction policy was executed and not executed, respectively) were applied with bias correction for reflecting the climate characteristics of the target basin. The analysis result of the agricultural water supply capacity in the future, after the agricultural reservoir embankment raising project is implemented, revealed that the water supply reliability and the agricultural water supply increased, regardless of the climate change scenarios. By simulating the reservoir water storage considering the instream flow post completion of the embankment raising project, it was found that water shortage in the reservoir in the future is not likely to occur when it is supplied with an appropriate instream flow. The range of instream flow tends to decrease over time under RCP 8.5, in which the greenhouse gas reduction policy was not executed, and the restoration of reservoir storage was lower in this scenario than in RCP 4.5, in which greenhouse gas reduction policy was executed.

• 대한한의학원전학회지
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• 제3권
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• pp.1-150
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• 1989

Oriental medicine thinks life and death as the following. 1. The universe seems to be a kind of organism which is divided into 3 branches, as Heaven, Earth and Man. Man is not created from nihil by the Creator. Heaven and Earth by their interaction operate to produce man. This is similiar that zygote is not created from nihil, and that sperm and ovum are transformed into zygote by their interaction. The symbolic meaning of sperm is Heaven, and that of ovum is Earth. Mind and body, as well as spirit and body, are not the real, but artificial words for the purpose of observing and expressing one man. So there is not spiritual substance as distinct from body. The expected life span of man is subjected to change, and is always becoming through life. Fate, the Creator and the world to come cannot be said to be. 2. After one's death, man is transformend into Heaven and Earth. Dying is this process of transformation. Although man comes into existence and closes one's life, the total life of the universe does not change. The criteria of determination of death is not in cell death, but in somatic death. Somatic death divided into 2 branches, one is heart-lung death, the other is brain death. For the standard of health changes ceaselessly as time goes by, aging and dying is not the process of losing health. Because of mind cannot be seperated from body, we'll feel at ease bodily and mentally in healthy dying. The completion of lifetimes is the value of healthy dying. 3. From the viewpoint of these, we must think to let a person die healthily is the right medical ethics. The way to let a person die healthily is divided into 3 branches, one is treatment, another is prevention and the other is promotion of health. We should treat and prevent death of sickness, but take care of healthy dying.

• Journal of Chest Surgery
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• 제53권2호
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• pp.58-63
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• 2020

Background: Despite progress in treatment, Stanford type A aortic dissection is still a life-threatening disease. In this study, we analyzed surgical outcomes in patients with Stanford type A aortic dissection according to the extent of surgery at Daegu Catholic University Medical Center. Methods: We retrospectively analyzed 98 patients with Stanford type A aortic dissection who underwent surgery at our institution between January 2008 and June 2018. Of these patients, 82 underwent limited replacement (hemi-arch or ascending aortic replacement), while 16 patients underwent total arch replacement (TAR). We analyzed in-hospital mortality, postoperative complications, the overall 5-year survival rate, and the 5-year aortic event-free survival rate. Results: The median follow-up time was 48 months (range, 1-128 months), with a completion rate of 85.7% (n=84). The overall in-hospital mortality rate was 8.2%: 6.1% in the limited replacement group and 18.8% in the TAR group (p=0.120). The overall 5-year survival rate was 78.8% in the limited replacement group and 81.3% in the TAR group (p=0.78). The overall 5-year aortic event-free survival rate was 85.3% in the limited replacement group and 88.9% in the TAR group (p=0.46). Conclusion: The extent of surgery was not related to the rates of in-hospital mortality, complications, aortic events, or survival. Although this study was conducted at a small-volume center, the in-hospital mortality and 5-year survival rates were satisfactory.

• 한국동물위생학회지
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• 제35권4호
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• pp.327-332
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• 2012

This study aimed to see if as companion animals living with human beings, dogs could provide emotional stability or play a therapeutic role for human beings. Of 12 middle school boys as victims of school violence, 6 were assigned to the experimental group that was provided with an animal-assisted therapy program over a total of 12 sections, one section per week, 60 minutes per section, between September and November 2011, followed by post-test 1 and, one month later, post-test 2. In the experimental composition, the remaining 6 boys were assigned to the comparison group that was allowed to read freely. Analysis was performed by using the scales of depression and self-esteem, and the results showed that the experimental group provided with the animal-assisted therapy program generated more significant therapeutic effects than the comparison group. The therapeutic effects were found to persist one month after the completion of the program. Therefore, it is believed that sensitive adolescents who suffer from depression or have lost self-esteem because of school violence can significantly benefit from an animal-assisted therapy program by reducing the recovery time or by getting lots of help with emotional stability. Further research on the basis of this study is expected to help adolescents with emotional therapy in other areas.

• 한국정보통신학회논문지
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• 제25권11호
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• pp.1655-1662
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• 2021

본 연구의 목적은 코로나-19로 인한 비대면 상황가운데 프로그래밍 과목을 프로젝트법으로 운영한 교수자의 교육과정 운영에 대한 사례연구를 통하여 시사점을 도출하는 데에 있다. 1학년 신입생 학생들을 대상으로 프로젝트 실시 전에 학생들의 학습상태를 판단하고자 설문을 실시하였다. 설문결과를 바탕으로 개인별 면담을 진행하여 교육에 대한 니즈를 파악 후, 프로젝트 구성을 위한 기본 문법과 프로젝트의 각 단계를 분절하는 강의를 구성하였다. 주간 퀴즈를 통한 반복학습을 유도하였으며 프로젝트 마감까지 시간을 미리 부여하여 피드백을 주었다. 23명(전체 학생 40명)은 프로젝트에 대한 수행을 완료하였고, 17명은 시험은 응시하였으나 프로젝트는 미완성하였다. 본 연구의 목적은 코로나-19로 인한 비대면 상황가운데 공대 실기과목을 프로젝트법으로 운영하면서 수업설계와 실행, 상호작용을 거쳐서 프로젝트를 수행할 수 있는가를 연구하였다는 점에서 의의가 있다.

• 한국지반신소재학회논문집
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• 제11권2호
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• pp.49-54
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• 2012

연약지반 개량공사에서 최종압밀침하량은 침하관리와 준공시기를 결정하는 데 중요하다. 설계 시 점토층의 최종압밀침하량의 산정은 압축지수를 이용하는 방법이 가장 많이 이용되고 있다. 압축지수는 압밀시험으로 얻어진 하중-침하 관계를 반대수좌표에 나타냈을 때 처녀압축곡선의 기울기이다. 종래에는 압밀층 전체를 한 개의 층으로 보고 최종압밀침하량을 산정해 왔으나, 압밀층을 여러 개의 층으로 분할했을 때 얻어지는 침하량의 차이를 알아보았다. 분할층 수와 상재하중의 크기가 압밀침하량에 미치는 영향에 대하여 분석한 결과는 다음과 같다. 분할층 수가 증가할수록 침하량은 증가하여 일정한 값에 수렴하며 이러한 양상은 상재하중의 크기와 무관하게 나타났다. 상재하중이 압밀층 두께에 비해 상대적으로 작을 때는 층분할효과가 매우 크게 나타났다. 보편적인 성토하중의 경우 층분할효과는 1.2-1.4 정도로 나타났으며 이 값은 최종압밀침하량 산정 시 안전율의 의미로 사용할 수 있을 것이다.

• Radiation Oncology Journal
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• 제32권3호
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• pp.156-162
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• 2014

Purpose: This study was designed to evaluate the efficacy and safety of topically applied recombinant human epidermal growth factor (rhEGF) for the prevention of radiation-induced dermatitis in cancer patients. Materials and Methods: From December 2010 to April 2012, a total of 1,172 cancer patients who received radiotherapy (RT) of more than 50 Gy were prospectively enrolled and treated with EGF-based cream. An acute skin reaction classified according to the Radiation Therapy Oncology Group 6-point rating scale was the primary end point and we also assessed the occurrence of edema, dry skin, or pruritus. Results: The percentage of radiation dermatitis with maximum grade 0 and grade 1 was 19% and 58% at the time of 50 Gy, and it became 29% and 47% after completion of planned RT. This increment was observed only in breast cancer patients (from 18%/62% to 32%/49%). Adverse events related to the EGF-based cream developed in 49 patients (4%) with mild erythema the most common. Skin toxicity grade >2 was observed in 5% of the patients. Edema, dry skin, and pruritus grade ${\geq}3$ developed in 9%, 9%, and 1% of the patients, respectively. Conclusion: Prophylactic use of an EGF-based cream is effective in preventing radiation dermatitis with tolerable toxicity. Further studies comparing EGF cream with other topical agents may be necessary.

• Radiation Oncology Journal
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• 제31권4호
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• pp.216-221
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• 2013

Purpose: The purpose of this retrospective study was to evaluate the efficacy and feasibility of short-course hypofractionated radiotherapy (RT) for the palliation of uterine cervical cancer. Materials and Methods: Seventeen patients with cancer of the uterine cervix, who underwent palliative hypofractionated 3-dimensional conformal radiotherapy between January 2002 and June 2012, were retrospectively analyzed. RT was delivered to symptomatic lesions (both the primary mass and/or metastatic regional lymph nodes). The total dose was 20 to 25 Gy (median, 25 Gy) in 5 Gy daily fractions. Results: The median follow-up duration was 12.2 months (range, 4 to 24 months). The median survival time was 7.8 months (range, 4 to 24 months). Vaginal bleeding was the most common presenting symptom followed by pelvic pain (9 patients). The overall response rates were 93.8% and 66.7% for vaginal bleeding control and pelvic pain, respectively. Nine patients did not have any acute side effects and 7 patients showed minor gastrointestinal toxicity. Only 1 patient had grade 3 diarrhea 1 week after completion of treatment, which was successfully treated conservatively. Late complications occurred in 4 patients; however, none of these were of grade 3 or higher severity. Conclusion: Short-course hypofractionated RT was effective and well tolerated as palliative treatment for uterine cervical cancer.