• 동의생리병리학회지
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• 제20권4호
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• pp.992-996
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• 2006

The study examined clinical effect of the 'Sexiang Shuhuo Jing' on serum CK and LDH activities and skeletal muscle ${\alpha}-actin$ mRNA expression concentration 140days after skeletal muscle injury in rats. The clinical research consisted of observing and measuring the serum CK, LDH activities and skeletal muscle ${\alpha}-actin$ mRNA expression, at the time of injury and during recovery. All experimental data were analyzed by repeated measurement with ANOVA on of SPSS(11.5v), accepting level for all significances was above ${\alpha}\;=.05.$ The results were as follows: That skeletal muscle injury in rats there existed a substantial increase serum CK, LDH activities and expression of skeletal muscle ${\alpha}-actin$ mRNA And Sexiang Shuhuo Jing treatment group's serum CK, LDH activities lower and faster recovery than control group. The 1 st day after skeletal muscle injury, Sexiang Shuhuo Jing treatment group's skeletal muscle ${\alpha}-actin$ mRNA expression was much more higher than control group, after 2 day's faster recovery normal level than control group. There existed a substantial increase again serum CK, LDH activities and skeletal muscle ${\alpha}-actin$ mRNA expression 3rd days after injury in control group. But in Sexiang Shuhuo Jing treatment group's can't be found that.

• 복식문화연구
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• 제9권3호
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• pp.511-522
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• 2001

Various art trends of the 20th century that contributed to the creation and development of abstract art had showed the transition from the convention of mere representation of the object to the formative sensitivity emphasizing self-expression. Noticing that such trends had influenced the fashion industry to move toward a free and individualized style, this study attempts to express the formative way from the existing art to wear, especially, based on early 20th century paintings, 5 casual wears were made which applied korean materials and silhouettes that are functional, sample and show traditional korea beauty. The purpose of this study is to search for a solution to expand the world market by producing dresses utilizing our own tradition that can be distinguished in the global market and that derive inspiration from the formative of the sensitivity of the paintings during the first half of the 20th century. It also aims to let national economy as a high-added industry. The result of this study are as follows: First, the expression method and element of various styles of art such as Fauvism, Expressionism and Cubism, during the period of transition to abstract art, clearly presented the direction toward the artistic liberation and made possible a new formative artistic expression of dress in the early years of the 20th century. Their ideas inspired the dress designers of the time with a reformative and creative sense of fashion and have greatly contributed to the development of a new era of uniqueness and individuality. Second, the color and the simplicity of form of the early 20th century paintings are suitable fro utilizing a motive of functional dresses and express unique and concise modern beauty. Third, it was confirmed that utilizing our tradition in contemporary dress can be a significant method of creation in which the uniqueness and creativity of Korean dress can be expressed, distinguishing it on the global scene, as well as inspire the originality and pride of our culture. Fourth, a possibility has been discovered. It is the functionality and uniqueness of aesthetic expression technique of the contemporary arts that can contribute to the fashion of tomorrow, by searching a modern fashion which was affected by the past and also by taking a look at the trend of modern fashion as the same field as casula wear.

• Toxicological Research
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• 제34권1호
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• pp.31-39
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• 2018

The objective of this study was to evaluate the antioxidant and anti-aging effects of marigold methanol extract (MGME) in human dermal fibroblasts. Total polyphenolic and flavonoid contents in MGME were 74.8 mg TAE (tannic acid equivalent)/g and 85.6 mg RE (rutin equivalent)/g, respectively. MGME ($500{\mu}g/mL$) increased 1,1-diphenyl-2-picryl hydrazyl (DPPH) and 2,2'-azino-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical-scavenging, and superoxide dismutase (SOD)-like antioxidant activities by 36.5, 54.7, and 14.8%, respectively, compared with the control. At $1,000{\mu}g/mL$, these activities increased by 63.7, 70.6, and 20.6%, respectively. MGME ($100{\mu}g/mL$) significantly increased the synthesis of type 1 procollagen by 83.7% compared with control treatment. It also significantly decreased Matrix Metalloproteinase-2 (MMP-2) activity and MMP-1 mRNA expression by 36.5% and 69.5%, respectively; however, it significantly increased laminin-5 mRNA expression by 181.2%. These findings suggest that MGME could protect human skin against photo-aging by attenuating oxidative damage, suppressing MMP expression and/or activity as well as by stimulating collagen synthesis.

• 한방안이비인후피부과학회지
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• 제28권2호
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• pp.1-12
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• 2015

Objective : The goal of this study is to identify the effects of extract ofGentianae sino-ornata(GSO) on the anti-oxidative activity of skin.For this purpose, several functions of GSO were analyzed in terms of skin-lightening activity and wrinkle improvement. Methods : Cell viability was measured by neutral red (NR) assay, and GSO showed highly efficacy in DPPH radical scavenging activity. The level of tyrosinase and matrix metalloproteinase-1 (MMP-1) in media was analyzed by ELISA kit, and the expressions of p-JNK and p-ERK was measured by Western blot. To elucidate inhibitory effects of GSO on melanin synthesis, I determined the tyrosinase activity and melanin production in B16F10 cells. Results : MMP-1 production in UVB-stimulated HDF cells was inhibited by GSO treatments, and also GSO inhibited protein expression levels of p-JNK and p-ERK. GSO significantly reduced tyrosinase activity and melanin synthesis in B16F10 cells. Conclusions : From these results, GSO appears to be effective on skin elasticity increase, wrinkle improvement, whitening as anti-aging activity.

• 한국패션뷰티학회지
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• 제6권2호
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• pp.80-86
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• 2008

This study is to understand how fluidity and natural features of Art Nouveau style are reflected in hair style of Art Nouveau age and Modem age and be a help to the trend analysis of hair style in the future. The study is conducted with the research on Art Nouveau expression in hair style and analysis of hair-show, trend presentation, documents related with hair style, TV drama, theses, journals and internet etc through advance research for Art Nouveau and Hair. The result of the analysis on Art Nouveau pattern in hair design is presented as below. First, it shows rounded, winding, flowing and thick-waved style of Art Nouveau pattern in modem long and short hair style. It also shows the beauty of long, bending and flexible lines, waving liveness and thin and slim lines and this is the Art Nouveau pattern that is also applied to other fields. In terms of decoration, it does not use tree vines, leaves and petals that are expressed in paintings of Art Nouveau age. Second, it shows natural up-style by lifting hair up with waved long hair that is one pattern of Art Nouveau and expresses hair style with feathers of birds, tree vines, leaves and petals etc for more decoration in animal pattern to make cute, romantic and elegant style in hair style.

• 한국축산식품학회지
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• 제35권2호
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• pp.164-170
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• 2015

The objective of this study was to evaluated the photoprotective effects of porcine placenta extract (PPE) on ultraviolet B (UVB)-induced oxidative stress in human keratinocytes (HaCaT) to evaluate its functional activities as a skin food ingredient. PPE prepared by subcritical water extraction was termed SPE, and subsequently digested by enzymes to prepare E-SPE. Increased intracellular reactive oxygen species (ROS) levels (192.0%) induced by UVB were decreased by SPE and E-SPE. SPE had more effective ROS scavenging activity than E-SPE treatment. UVB treatment increased expression of tissue inhibitor of metalloproteinase 1 (TIMP-1), and this elevated expression was decreased by E-SPE treatment. High-dose treatment with E-SPE (50 and 100 µg/mL) reduced TIMP-1 expression levels of UVB-C (control) to 33.5 and 34.6%, respectively. In contrast, at low SPE doses (1 and 10 µg/mL), the treatment slightly decreased TIMP- 1 expression levels to 73.3% and 71.3% of UVB-C, respectively. In conclusion, the present study demonstrated the protective effect of SPE and E-SPE against UVB damage in keratinocytes via ROS scavenging, down-regulating MMP-2 expression and up-regulating TIMP- 1 expression. This highlights the potential for SPE as an ingredient in the preparation of functional food against photoaging.

• Toxicological Research
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• 제31권2호
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• pp.165-172
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• 2015

Cornus officinalis is widely distributed in Korea, and its fruit has been used to make as herbal drug for traditional medicine in Korea, Japan, and China because of its tonic, analgesic, and diuretic properties. However, the effects of C. officinalis methanol extract (COME) on melanogenesis remain poorly understood. We evaluated the melanogenic capability of COME in melan-a cells, which are immortalized mouse melanocytes. COME increased melanin synthesis in a dose-dependent manner. Treatment with $12.5{\mu}g/mL$ of COME significantly increased melanin content by 36.1% (p < 0.001) to a level even higher than that (31.6%) of 3-isobutyl-1-methyl-xanthine, a well-known pigmentation agent. COME also upregulated tyrosinase activity and its messenger RNA and protein expression. In addition, COME upregulated the expression of tyrosinase-related proteins 1 and 2 and microphthalmia-associated transcription factor-M messenger RNA expression. These results imply that COME may be appropriate for development as a natural product to treat hair graying.

• 융합정보논문지
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• 제12권1호
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• pp.144-152
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• 2022

본 연구에서는 생태교란종으로 지정되어 대량으로 방제되는 영국갯끈풀의 에탄올 추출물을 활용하여 여러가지 생리활성을 평가하고 화장품 원료로서의 활용 가능성을 확인하고자 하였다. 항산화 활성은 라디컬 소거법인 DPPH와 ABTS assay 및 환원력을 통한 FRAP과 같은 화학적 방법으로 조사한 결과, 영국갯끈풀 지상부 에탄올 추출물의 항산화 활성이 우수하였다. 각 추출물 농도 0.5 mg/mL 이하 조건에서 RAW264.7 cell과 NHDF cell에 대한 세포독성은 관찰되지 않았다. LPS로 활성화 된 RAW264.7 세포에서 증가된 염증매개물질 NO와 사이토카인 생성량은 지하부 에탄올 추출물에 의해 뚜렷하게 감소되었다. 또한 NHDF cell을 지상부와 지하부 두 추출물로 처리하여 collagen 합성과 피부 수분 유전자 발현을 조사한 결과 높은 항주름 및 보습 효능을 나타냈다. 이와 같은 결과를 통하여 영국갯끈풀 에탄올추출물은 기능성화장품의 생리활성 물질에 대한 유용한 바이오 자원으로서의 활용 가능성이 우수함을 확인하였다.

• 패션비즈니스
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• 제15권2호
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• pp.131-144
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• 2011

The purpose of this study is to propose 3D art make-up design process by reproducing real objects through preliminary digital drawing with Photoshop (Photo Shop CS4.0, Adobe, USA) and using special make-up that has never been done previously, and produce creative problem solving plan to make concrete expanding thoughts and ideas. As for this study method, this study was composed of preliminary study, literature study by book examination and positive study on design process that performed preparatory work and reproduced real objects. Real case study by art make-up design process can improve effective design expressing ability by utilizing special make-up, diversify techniques, extend expression areas by materials, and create unique design. In addition, preliminary work by digital drawing, a process to predict real object work in advance, could reduce time and cost while improving work skill for work production, raise design accuracy and make easy the modification of idea. This study is anticipated to activate digital make-up by various digital techniques including Photoshop.

• 조형예술학연구
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• 제10권
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• pp.51-72
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• 2006

민화가 갖는 조형적 특성이 현대 한국화 작품에서 재해석되고 있는데 이는 민화가 지니고 있는 조형적 특성에서 오늘날 현대 한국화가 나아가야 할 방법론을 찾아보는 것이다. 그 표현들을 보면 민화에서 나타나는 도상의 재현, 평면화와 다시점적 표현 방법의 재해석, 민화 도상들을 오브제화 하고 혼성모방을 하는 등 실험성을 나타내기도 한다. 이 모든 표현들이 '민화'를 통한 현대 한국화의 방법들을 제시하는 것들이다. 현대 한국화 표현에서 민화는 오래전부터 응용되었지만 관심이 더욱 높아진 것은 1980년대 들어서이다. 당시 리얼리즘 미술의 민족적 표현 방식과 채색화의 등장으로 인하여 민화에서 나타나는 전통적 오방색과 서민적 내용 그리고 도상들을 차용하면서 점차 작가들이 민화를 재해석하여 자신의 작품 속에 등장시키기 시작하였던 것이다. 특히 '한국의 미'에 대한 관심이 민화에 대한 관심으로 나타났고, 민화는 전통적 조형 표현 방법에 있어 중요한 '한국의 미'를 제공하였다. 본 연구에서는 조선조 민화에서 나타나는 도상을 재현하거나 재해석하여 오늘날 한국화의 새로운 표현으로 등장시킨 작가들의 작품들을 살펴보고 그 작품들에서 어떠한 특성들이 있는가 하는 것을 알아보는 것을 목적으로 한다. 이와 같은 목적을 해결하기 위하여 민화에서 나타나는 조형적인 특성을 변용하거나 재해석하여 현대적인 작품세계로 나아가는 작가들을 '민화 이미지의 재수용' '민화 특성의 재해석' '실험적 표현' 등으로 나누어 살펴보았다. 그 결과 민화가 고전적인 표현이며 조선시대에서만 사용된 조형적 방법이 아니라 오늘날 조형 방법론으로 재해석할 수 있는 민족적 표현임을 알 수 있다.