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Effect of 'Sexiang Shuhuo Jing' for CPK, LDH Activities and Skeletal Muscle ${\alpha}-actin$ mRNA Expression after Skeletal Muscle in Rats  

Kim, Jin-Hang (College of Physical Education, Hanyang University)
Song, Je-Ho (Department of Beauty Design College of Human Enviornamental Science Wonkwang University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.20, no.4, 2006 , pp. 992-996 More about this Journal
Abstract
The study examined clinical effect of the 'Sexiang Shuhuo Jing' on serum CK and LDH activities and skeletal muscle ${\alpha}-actin$ mRNA expression concentration 140days after skeletal muscle injury in rats. The clinical research consisted of observing and measuring the serum CK, LDH activities and skeletal muscle ${\alpha}-actin$ mRNA expression, at the time of injury and during recovery. All experimental data were analyzed by repeated measurement with ANOVA on of SPSS(11.5v), accepting level for all significances was above ${\alpha}\;=.05.$ The results were as follows: That skeletal muscle injury in rats there existed a substantial increase serum CK, LDH activities and expression of skeletal muscle ${\alpha}-actin$ mRNA And Sexiang Shuhuo Jing treatment group's serum CK, LDH activities lower and faster recovery than control group. The 1 st day after skeletal muscle injury, Sexiang Shuhuo Jing treatment group's skeletal muscle ${\alpha}-actin$ mRNA expression was much more higher than control group, after 2 day's faster recovery normal level than control group. There existed a substantial increase again serum CK, LDH activities and skeletal muscle ${\alpha}-actin$ mRNA expression 3rd days after injury in control group. But in Sexiang Shuhuo Jing treatment group's can't be found that.
Keywords
Sexiang Shuhuo Jing treatment; serum CK; LDH activities; skeletal muscle injury; skeletal muscle ${\alpha}-actin$ mRNA;
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