• 제목/요약/키워드: the bio current

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Island ecology on biological-cultural diversities and human adaptation in seascapes

  • Hong, Sun-Kee
    • Journal of Ecology and Environment
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    • 제33권2호
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    • pp.115-120
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    • 2010
  • The Asian cultural landscape is a mirrored ecosystem of great complexity, formed by the interaction of man and nature, coupled with a host of ecological processes. The human dependencies on and environmental adaptation of the bio-organisms and the surrounding landscape constitute the typical cultural landscape. Islands are a good example of a cultural landscape, and each mosaic pattern of marine and coastal ecosystems reflects bio-cultural diversity. Along with land-use patterns, wise use of biological organisms and indigenous knowledge has expanded to islands in the Asia-Pacific region in several ways (sea current and human impact, etc.). Loss in biodiversity and landscape diversity as well as cultural diversity owing to global warming and rapid urbanization are emerging issues for island ecosystems all over the world. In order to sustain the historical coexistence between man and natural systems, we ecologists must continue to search for a holistic solution for academic consilience. In this paper, I present the vision and practical characteristics of island ecology with a view toward the conservation of the traditional landscape and bio-cultural diversities in the seascape.

Biocreative Alveolar Molding Plate Treatment (BioAMP) for neonatal unilateral cleft lip and palate with excessively wide alveolar cleft and maxillary arch width

  • HyeRan Choo;HyoWon Ahn
    • 대한치과교정학회지
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    • 제54권1호
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    • pp.69-73
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    • 2024
  • Since its inception in Europe in the 1950s, alveolar molding treatment for neonates with complete cleft lip and palate has undergone significant evolution in both design and application methodology, demonstrating effectiveness in normalizing the alveolar cleft and nasal shape. However, excessively wide alveolar clefts accompanied by disproportionately wide total maxillary arch pose significant challenges when utilizing conventional alveolar molding methods involving cyclical adding and grinding of acrylic on molding plates. The current report introduces a novel alveolar molding method named Biocreative Alveolar Molding Plate Treatment (BioAMP), which can normalize the maxillary alveolar cleft and arch shape without laborious conventional acrylic procedures. BioAMP sets the target arch form and provides unrestricted space for natural growth of the maxillary alveolar bones while systematically reducing the total maxillary arch width in precise increments. Two exemplary cases are presented as proof-of-concept, showcasing the clinical innovation of BioAMP.

PubMine: An Ontology-Based Text Mining System for Deducing Relationships among Biological Entities

  • Kim, Tae-Kyung;Oh, Jeong-Su;Ko, Gun-Hwan;Cho, Wan-Sup;Hou, Bo-Kyeng;Lee, Sang-Hyuk
    • Interdisciplinary Bio Central
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    • 제3권2호
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    • pp.7.1-7.6
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    • 2011
  • Background: Published manuscripts are the main source of biological knowledge. Since the manual examination is almost impossible due to the huge volume of literature data (approximately 19 million abstracts in PubMed), intelligent text mining systems are of great utility for knowledge discovery. However, most of current text mining tools have limited applicability because of i) providing abstract-based search rather than sentence-based search, ii) improper use or lack of ontology terms, iii) the design to be used for specific subjects, or iv) slow response time that hampers web services and real time applications. Results: We introduce an advanced text mining system called PubMine that supports intelligent knowledge discovery based on diverse bio-ontologies. PubMine improves query accuracy and flexibility with advanced search capabilities of fuzzy search, wildcard search, proximity search, range search, and the Boolean combinations. Furthermore, PubMine allows users to extract multi-dimensional relationships between genes, diseases, and chemical compounds by using OLAP (On-Line Analytical Processing) techniques. The HUGO gene symbols and the MeSH ontology for diseases, chemical compounds, and anatomy have been included in the current version of PubMine, which is freely available at http://pubmine.kobic.re.kr. Conclusions: PubMine is a unique bio-text mining system that provides flexible searches and analysis of biological entity relationships. We believe that PubMine would serve as a key bioinformatics utility due to its rapid response to enable web services for community and to the flexibility to accommodate general ontology.

Current Status of Microbial Phenylethanoid Biosynthesis

  • Kim, Song-Yi;Song, Min Kyung;Jeon, Ju Hyun;Ahn, Joong-Hoon
    • Journal of Microbiology and Biotechnology
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    • 제28권8호
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    • pp.1225-1232
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    • 2018
  • Phenylethanoids, including 2-phenylethanol, tyrosol, and salidroside are a group of phenolic compounds with a C6-C2 carbon skeleton synthesized by plants. Phenylethanoids display a variety of biological activities, including antibacterial, anticancer, anti-inflammatory, neuroprotective, and anti-asthmatic activities. Recently, successful microbial synthesis of phenylethanoids through metabolic engineering and synthetic biology approaches has been reported and could allow phenylethanoid production from alternative microbial sources. Here, we review the recent achievements in the synthesis of phenylethanoids by microorganisms. The work done so far will contribute to the production of diverse phenylethanoids using various microbial systems and facilitate exploration of further diverse biological activities of phenylethanoids.

Glass Slide-based Immunosensing for C-Reactive Protein Using Quantum Dot-Antibody Conjugate

  • Kim, Namsoo;Oh, Sun Mi;Kim, Chong-Tai;Cho, Yong Jin
    • 산업식품공학
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    • 제14권1호
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    • pp.21-26
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    • 2010
  • C-Reactive protein (CRP), which is an 118 kDa pentameric protein, was secreted by the liver is an important biomarker for coronary disease, hypertension and inflammation. In this study, a method for CRP detection exploiting quantum dot (Qdot)-antibody conjugate was developed according to an indirect-competitive immunosensing protocol. For this purpose, a streptavidin-bound $Qdot_{605}$ was linked with a separately prepared biotinylated monoclonal antirat CRP antibody to produce a Qdot-antibody conjugate. The immunosensing was performed at 0.1 and 20 nM of the coating antigen and conjugate, respectively. The current method was found very sensitive in CRP detection, judging from the concentration-dependent fluorescence emission.

Enhanced Electrochemifluorescence and Reduction Mechanism of Acetoxy Coumarin Derivatives in Acetonitrile Solution

  • Kim, Sung-Hyun;Jung, Eun-Joo;So, Eun-Mi;Shen, Chang-Zhe;Chun, Hyun-Ja;Kim, Young-Man;Kim, Il-Kwang
    • Bulletin of the Korean Chemical Society
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    • 제27권9호
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    • pp.1329-1334
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    • 2006
  • The electrochemical reduction of coumarin, 7-acetoxy-4-methyl coumarin (AMC), and 7-acetoxy-4-bromomethyl coumarin (ABMC), in 0.1 M tetraethyl ammonium perchlorate/acetonitrile solution was carried out by direct current, differential pulse polarography, cyclic voltammetry, and controlled potential coulometry. The electrochemical reduction of ABMC was proceeded through three steps of electron transfer coupled with the chemical reactions. The color of solution was changed to yellow when the carbonyl group was reduced during 2nd step (-1.8 volts) and independented with cleavage of bromo group. Highest fluorescence intensity showed when the electrochemical reduction of AMC was controlled at near the potential (-2.3 volts vs. Ag/AgCl).

태양전지를 이용한 원격조종 중경제초기 개발 (Development of a Remote Controlled Weeder Driven by Solar Battery Power)

  • 김태수;장익주
    • Journal of Biosystems Engineering
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    • 제32권2호
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    • pp.91-96
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    • 2007
  • In this study, a prototype remote controlled weeder using solar module was developed and the evaluations of weeding, side walking and weeding performance were conducted to see if actual application was feasible in the paddy field. When traveling, the loss electric current was 8 to 15 A depending on operating and soil conditions. The average traveling speed was 0.25 m/s and the average slippage was 18%. When it side walked row by row, electric current consumption was 7 A on the average. When wheel rotors line went initially up and last down, electric current consumption was 12 to 15 A due to soil resistance. Electric current consumption when shifting wheel rotors line was less than 5 A due to no resistance. Field efficiency was 105 min/10a based on the test field. Operation was able to be done for 4.16 hours continually by 52 AH battery based on 300 W average maximum power consumption and 4.6 hours under sunny day considering solar module.

Current Development in Bio-implantable Sensors

  • Swarup, Biswas;Yongju, Lee;Hyojeong, Choi;Hyeok, Kim
    • 센서학회지
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    • 제31권6호
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    • pp.403-410
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    • 2022
  • Flexible and wearable sensing technologies have emerged as a result of developments in interdisciplinary research across several fields, bringing together various subjects such as biology, physics, chemistry, and information technology. Moreover, various types of flexible wearable biocompatible devices, such customized medical equipment, soft robotics, bio-batteries, and electronic skin patches, have been developed over the last several years that are extensively employed to monitor biological signals. As a result, we present an updated overview of new bio-implantable sensor technologies for various applications and a brief review of the state-of-the-art technologies.