• Title/Summary/Keyword: t-z method

Search Result 315, Processing Time 0.032 seconds

Anti-Toxoplasma Activities of Zea Mays and Eryngium Caucasicum Extracts, In Vitro and In Vivo

  • Ahmadpour, Ehsan;Ebrahimzadeh, Mohammad Ali;Sharif, Mehdi;Edalatian, Sara;Sarvi, Shahabeddin;Montazeri, Mahbobeh;Mehrzadi, Saeed;Akbari, Mohammad;Rahimi, Mohammad Taghi;Daryani, Ahmad
    • Journal of Pharmacopuncture
    • /
    • v.22 no.3
    • /
    • pp.154-159
    • /
    • 2019
  • Objectives: Toxoplasmosis is a worldwide health problem that caused by intracellular apicomplexan parasite, Toxoplasma gondii (T. gondii). Considering that the available drugs for toxoplasmosis have serious host toxicity, the aim of the current study was to survey the in vitro and in vivo anti-Toxoplasma activity of Zea mays (Z. mays) and Eryngium caucasicum (E. caucasicum) extracts. Methods: Four concentrations (5, 10, 25, and $50mg\;mL^{-1}$) of Z. mays and E. caucasicum methanolic extracts for 30, 60, 120, and 180 min were incubated with infected macrophages and then the viability of RH strain of T. gondii tachyzoites was evaluated by trypan blue staining method. Also, we evaluated the survival rate of acutely infected mice with the extracts (100 and $200mg\;kg^{-1}\;day^{-1}$) intraperitoneally for 5 days after infection with $2{\times}104$ tachyzoites of T. gondii. Results: The anti-Toxoplasma effect of the methanolic extracts were extremely significant compared to the negative control group in all exposure times (P < 0.05). The Z. mays (10, 25 and $50mg\;mL^{-1}$) killed 100% of the parasites after 180 and 120 min exposure, respectively. Also, high toxoplasmacidal activity was observed with E. caucasicum extract. Furthermore, treatment of experimentally infected mice with the Z. mays (100, $200mg\;kg^{-1}\;day^{-1}$) and E. caucasicum ($100mg\;kg^{-1}\;day^{-1}$) significantly increased their survival rate compared to untreated infected control (P < 0.05). Conclusion: These extracts are promising candidates for further medicine development on toxoplasmosis. However, further investigations are necessary to clarify effective fractions of the Z. mays and E. caucasicum extracts and the mechanisms of action.

Z-Source Inverter (Z-Source 인버터)

  • Choi H.L.;Jung T.U.;Jeon J.G.;Yu Tao;Lee D.H.;Kang P. S.;Choi J.H.;Park S.J.
    • Proceedings of the KIPE Conference
    • /
    • 2006.06a
    • /
    • pp.545-548
    • /
    • 2006
  • This paper presents control method of a Z-source inverter and their relationships of voltage boost versus modulation index. A maximum boost control is presented to produce the maximum voltage boost(or voltage gain)under a given modulation index. The control method, relationships of voltage gain versus modulation index, and voltage stress versus voltage gain are analyzed in detail and verified by experiment.

  • PDF

Thermoelectric Performance Enhancement of Sintered Bi-Te Pellets by Rotary-type Atomic Layer Deposition (로터리형 원자층 증착법을 이용한 Bi-Te계 소결체의 열전 성능 개선)

  • Myeong Jun Jung;Ji Young Park;Su Min Eun;Byung Joon Choi
    • Journal of Powder Materials
    • /
    • v.30 no.2
    • /
    • pp.130-139
    • /
    • 2023
  • Thermoelectric materials and devices are energy-harvesting devices that can effectively recycle waste heat into electricity. Thermoelectric power generation is widely used in factories, engines, and even in human bodies as they continuously generate heat. However, thermoelectric elements exhibit poor performance and low energy efficiency; research is being conducted to find new materials or improve the thermoelectric performance of existing materials, that is, by ensuring a high figure-of-merit (zT) value. For increasing zT, higher σ (electrical conductivity) and S (Seebeck coefficient) and a lower κ (thermal conductivity) are required. Here, interface engineering by atomic layer deposition (ALD) is used to increase zT of n-type BiTeSe (BTS) thermoelectric powders. ALD of the BTS powders is performed in a rotary-type ALD reactor, and 40 to 100 ALD cycles of ZnO thin films are conducted at 100℃. The physical and chemical properties and thermoelectric performance of the ALD-coated BTS powders and pellets are characterized. It is revealed that electrical conductivity and thermal conductivity are decoupled, and thus, zT of ALD-coated BTS pellets is increased by more than 60% compared to that of the uncoated BTS pellets. This result can be utilized in a novel method for improving the thermoelectric efficiency in materials processing.

Structure and Magnetic Properties on Synthesis Route of Co2Z-type Barium Hexaferrite (Co2Z-type Barium Hexaferrite의 합성방법에 따른 결정구조 및 자기적 특성)

  • Baek, In Seung;Nam, In Tak
    • Journal of the Korean Magnetics Society
    • /
    • v.24 no.1
    • /
    • pp.1-10
    • /
    • 2014
  • $Co_2Z$-type barium ferrites ($Ba_3Co_2Fe_{24}O_{41}$) were synthesized using variation method. First, M-type, $Co_2Y$-type and $Co_2Z$-type synthesized by hydrothermal method. Second, M- and Y-type precursors for synthesis of $Co_2Z$ hexaferrite by hydrothermal and ball milling method. the morphology, structure and magnetic properties of the barium ferrite particles were characterized using XRD, FESEM, VSM, impedance. As a result, Single phase of M-type and $Co_2Y$-type were obtained. Manufactured powders of M+Y ball milling, M+Y hydrothermal were similar to single phase of $Co_2Z$-type hexaferrite, all powders were obtained theoretical magnetization (50 emu/g). The largest initial permeability were obtained $Co_2Z$ hexaferrite synthesized by reagent precusor, With increasing calcination temperature was lowered the initial permeability. In another synthesis didn't almost that little change could be found.

A FIXED POINT APPROACH TO STABILITY OF ADDITIVE FUNCTIONAL INEQUALITIES IN FUZZY NORMED SPACES

  • Kim, Chang Il;Park, Se Won
    • Journal of the Chungcheong Mathematical Society
    • /
    • v.29 no.3
    • /
    • pp.453-464
    • /
    • 2016
  • In this paper, we investigate the solution of the following functional inequality $$N(f(x)+f(y)+f(z),t){\geq}N(f(x+y+z),mt)$$ for some fixed real number m with $\frac{1}{3}$ < m ${\leq}$ 1 and using the fixed point method, we prove the generalized Hyers-Ulam stability for it in fuzzy Banach spaces.

ESTIMATION OF THE SURVIVAL RATE IN FISH POPULATION FROM THE LENGTH COMPOSITION AND THE GROWTH EQUATION1 (체장조성과 성장곡선식에서 생잔율을 추정하는 방법)

  • SHIN Sang Taek
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.10 no.2
    • /
    • pp.137-143
    • /
    • 1977
  • A study has been made to find out a new method of calculating the survival rate of a fish population from length composition and growth equation. 1. In the steady state of the fish population, let the total mortality rate be z, the age of complete recruitment $\alpha$, and the number of $\chi$ year class $N_\chi$. Then ire obtain $$N\chi=N\alpha\;\exp\;{-z(\chi-\alpha)}$$ Let the oldest age in the catch be h, the average age between the age of complete recruitment and the oldest age in the catch $U\chi$. Then we have $$U\chi=\frac{a-b\;\exp\;(-z(b-a))}{1-\exp\;(-z(b-a))}+\frac{1}{z}....(1)$$ and then let be infinite. Then we obtain $$Z=\frac{1}{U\chi-\alpha....(2)$$ 2. Calculating numerical value of $U\chi$ from age composition table and growth equation and substitute in (1) or (2) for it, we may obtain the value of s and $\varrho^{-z}$. 3. This method is applied t a case of yellow croaker in the Yellow Sea and the East China Sea. The results are as follows: Total mortality rate 0.82595 Survival rate 0.43782 95 percent confidence interval 0.43767-0.43797.

  • PDF

Distribution of Magnetic Field Depending on the Current in the μ-turn Coil to Capture Red Blood Cells (적혈구 포획용 미크론 크기 코일에 흐르는 전류의 크기에 따른 자기장 분포 특성)

  • Lee, Won-Hyung;Chung, Hyun-Jun;Kim, Nu-Ri;Park, Ji-Soo;Lee, Sang-Suk;Rhee, Jang-Roh
    • Journal of the Korean Magnetics Society
    • /
    • v.25 no.5
    • /
    • pp.162-168
    • /
    • 2015
  • The ${\mu}$-turn coil having a width of ${\mu}m$ on the GMR-SV (giant magnetoresistance-spin valve) device based on the antiferromagnetic IrMn layer was fabricated by using the optical lithography process. In the case of GMR-SV film and GMR-SV device, the magnetoresistance ratios and the magnetic sensitivities are 4.4%, 2.0%/Oe and 1.6 %, 0.1%/Oe, respectively. In the y-z plane the distribution of magnetic field of GMR-SV device and $10{\mu}$-turns coil which put under the several magnetic bead(MB)s with a diameter of $1{\mu}m$ attached to RBC (red blood cell) was analyzed by the computer simulation using the finite element method. When the AC currents of 20 kHz from 0.1 mA to 10.0 mA flow to the 10 turns ${\mu}$-coil, the magnetic field at the position of $z=0{\mu}m$ at the center of coil was calculated from $30.1{\mu}T$ to $3060{\mu}T$ in proportion to the current. The magnetic field at the position of $z=10{\mu}m$ was decreased to one-sixth of that of $z=0{\mu}m$. It was confirmed that the $10{\mu}$-turn coil having enough magnitude of magnetic field for the capture of RBC is possible to use as a biosensor for the detection of magnetic beads attached to RBC.

Early and Mid-Term Results after Operations for Pulmonary Atresia with Intact Ventricular Septum (온전한 심실중격을 갖고 있는 폐동맥폐쇄증의 수술 후 조기 및 중기 성적)

  • 성시찬;전희재;조광조;우종수;이형두
    • Journal of Chest Surgery
    • /
    • v.33 no.6
    • /
    • pp.476-486
    • /
    • 2000
  • Background: Pulmonary atresia with intact ventricular septum(PA/IVS) is an anatomically heterogenous anomaly with a variety of surgical strategies possible. The purpose of the study is to evaluate the influence of right ventricular size on the early and midterm results of surgical repair of PA/IVS. Material and method: Medical records of 20 consecutive patients with PA/IVS operated on between January 1993 and August 1999 were retrospectively reviewed. There were 12 boys and 8 girls whose ages ranged from 2 days to 14.5 months (median 6 days). Their body weight ranged from 2.52kg to 9.35 kg(median 3.18kg). The preoperative Z-value of the diameter of the tricuspid valve(T-valve) was less than or -4 in 5 patients, between -4 and -2 in 1, between -2 and 0 in 7, between 0 and 2 in 6, and greater than or 2 in 1. All patients who had z-value of tricuspid valve greater than -2.05 were attempted biventricular repair(n=15) and all patients who had it smaller than -4.4 underwent systemic-pulmonary shunt operation only(n=3) or bidirectinal cavopulmonary shunt with right ventricular reconstruction(n=2). Result: Two early deaths(2/20, 10%) occurred. Both were infants who underwent transannular patch with shunt. One of these two had huge right ventricle(Z-value of tricuspid valve = 5). There were 2 late non-cardiac deaths 3 and 7 months after operations respectively. Follow-up was completed in all children at a mean of 35.3 months(range, 5 to 54 months). 10 of 11 survivors who underwent transannular patch or valvotomy with or without shunt procedure were in NYHA functional class I even though some of them had small interatrial communication or patent shunt. All three patients who had shunt procedure only at initial palliation completed Fontan procedures with no death. Two patients who underwent right ventricular outflow reconstruction with bidirectional cavopulmonary shunt were also in good condition. Conclusion: The transanular RVOT patch or valvotomy with or without systemic-pumonary shunt as an initial palliative procedure to achieve biventricular repair for the patients who had neither too small nor too large right ventricle(-2.05$\leq$Z-value of T-value of T-valve$\leq$2) could be performed at low operative risk(1/14 7.1%). Systemic-pulmonary shunt procedure and bidirectional cavopulmonary shunt procedure for the patients who had small right ventricle(Z-value of T-valve$\leq$4.4) could be also performed with low risk. But a patient with huge right atrium and ventricle(Z-value of t-valve=5) had poor operative result.

  • PDF

Validation of Analytical Method for Male Sex Hormone Monitoring in Urine due to the Chemical Castration (성충동약물치료 시행에 따른 소변 중 남성호르몬의 분석법 확립)

  • Jeong, Sujin;Baeck, Seungkyung;Park, Sunhye;Son, Kkonnip;Park, Yonghoon;Lee, Sangki
    • YAKHAK HOEJI
    • /
    • v.57 no.5
    • /
    • pp.330-336
    • /
    • 2013
  • "The Act on Medication Treatment of Sexual Impulse of Sex Offenders" known as chemical castration has been effective since July 2011 in Korea. According to the law, monitoring of male sex hormone in urine is enforced to request National Forensic Service more than once a month after injection of medicine designed to reduce sex impulse. We established a rapid and sensitive method for the monitoring of testosterone (T) and epitestosterone (E) in human urine by liquid chromatography with tandem mass spectrometry (LC-MS/MS). Three mL of urine was pretreated by solid-phase extraction for purification and performed enzymatic hydrolysis. The pretreated samples were extracted twice with 2 ml of ethyl acetate and n-hexane (2 : 3). The separation was applied on Thermo Hypersil GOLD C18 column ($1.9{\mu}m$, $100{\times}2.1mm$). A gradient elution of methanol and water of 0.1% formic acid were used as mobile phase and the retention time was less than 10 min. LC-MS/MS system coupled with an electrospray ionization source was performed in multiple reaction monitoring mode. The transitions of the analytes executed as following: m/z $289{\rightarrow}97$, 109 for T and E, m/z $292{\rightarrow}109$ for $T-d_3$ and $E-d_3$ as internal standards. The validation results of the method were satisfactory. The limits of detection were 0.05 ng/ml and the limits of quantification were 0.1 ng/ml. This method was successfully applied to real human urine sample. The developed method will be useful for monitoring T/E ratio in urine of sex offenders.

Analysis of Pile Groups Considering Pile-Cap Interaction (말뚝-캡 강성을 고려한 군말뚝기초의 해석)

  • 정상섬;원진오;허정원
    • Proceedings of the Korean Geotechical Society Conference
    • /
    • 2001.03a
    • /
    • pp.363-370
    • /
    • 2001
  • A computationally efficient algorithm to analyze a group pile behavior is proposed by consideration of both soil-pile and pile-cap interactions. Using toad transfer method the nonlinear characteristics of the soil-pile interaction for a single pile is modeled by piecewise linear soil springs (p-y, t-z, and q-z curves). Beam-column method, one of the most practical approaches, is used for numerical modeling of the soil-pile system. In addition to the group effect resulting from the soil-pile-soil interaction, for a more realistic analysis it is essential to consider the effect of pile-cap interaction including geometric configuration of the piles in a group and conectivity conditions between piles and the cap. This paper mainly focuses on the pile-cap interaction and the development of a rational numerical procedure of its incorporation with the beam-column method.

  • PDF