• 대한방사선기술학회지:방사선기술과학
• /
• 제46권3호
• /
• pp.207-217
• /
• 2023

Image noise reduction algorithm performs important functions in light microscopy. This study aims to systematically review the research trend of types and performance evaluation methods of noise reduction algorithm in light microscopic images. A systematic literature search of three databases of publications from January 1985 to May 2020 was conducted; of the 139 publications reviewed, 16 were included in this study. For each research result, the subjects were categorized into four major frameworks-1. noise reduction method, 2. imaging technique, 3. imaging type, and 4. evaluation method-and analyzed. Since 2003, related studies have been conducted and published, and the number of papers has increased over the years and begun to decrease since 2016. The most commonly used method of noise reduction algorithm for light microscopy images was wavelet-transform-based technology, which was mostly applied in basic systems. In addition, research on the real experimental image was performed more actively than on the simulation condition, with the main case being to use the comparison parameter as an evaluation method. This systematic review is expected to be extremely useful in the future method of numerically analyzing the noise reduction efficiency of light microscopy images.

• 치위생과학회지
• /
• 제24권2호
• /
• pp.84-96
• /
• 2024

Background: Recent studies have elucidated the quorum-sensing mechanisms, biofilm formation, inter-pathogen interactions, and genes related to oral pathogens. This review aims to explore the recent expansion of drug targets against oral pathogens and summarize the current research on novel antibiotic substances derived from marine organisms that target oral pathogens. Methods: A comprehensive literature review summarized the novel mechanisms pertaining to quorum-sensing signal transmission systems, biofilm formation, and metabolite exchange in oral pathogens. The amino acid sequences of the 16 proteins identified as potential drug targets were systematically classified and compared across various oral microorganisms. Results: Through a literature review, we identified nine studies researching quorum sensing signaling inhibitors targeting oral pathogens. A comparison of the amino acid sequences of 16 potential drug targets in oral microorganisms revealed significant differences between oral pathogens and beneficial oral symbiotic microorganisms. These findings imply that it is possible to design drugs that can bind more selectively to oral pathogens. Conclusion: By summarizing the results of recent research on the signaling mechanisms that cause pathogenicity, new drug targets against oral pathogens were proposed. Additionally, the current status of developing new antibiotics for oral pathogens using recently developed quorum sensing inhibitors and natural products derived from marine organisms was introduced. Consequently, marine natural products can be used to develop drugs targeting new proteins in oral pathogens.

• 한국정보시스템학회지:정보시스템연구
• /
• 제19권4호
• /
• pp.1-24
• /
• 2010

Over the past three decades, services have become the largest part of most industrialized nations' economies but it is the least-studied part of the economy. One approach is to develop a general theory of service with well-defined questions, tools, methods, and practical implications of society. The purpose of this study was to propose a service systems model to systematically approach a service research. For this purpose, we conducted literature review about business model and extant service systems researches. Based on a literature review, we propose a service systems model that comprises value proposition, participants, shared information/knowledge, organizational capability, value network, and technology. Implications for practice and recommendations for additional research were discussed.

• 정보관리학회지
• /
• 제13권2호
• /
• pp.39-71
• /
• 1996

도서관 환경에서 전자정보가 점차 중요한 위치를 차지하면서 정보의 성격과 그를 담아내는 정보매체의 기술적 요소들이 새롭게 조명되고 있다. 이 글에서는 디지털 도서관이 개발되고 하이퍼미디어 정보 환경의 특성을 이론적으로 정리하고, 멀티미디어 데이터의 응용에 필요한 관련 기술과 표준안들을 덱스트와 비텍스트 정보유형으로 나누어 구체적으로 살펴본다. 새로운 환경인 디지털 도서관의 도서관 실무자와 연구자 모두에게 시급히 요구되는 전문적 과정과 역할을 기술하고 있다.

• 보건행정학회지
• /
• 제23권4호
• /
• pp.397-414
• /
• 2013

There have been numerous attempts at finding factors associated with profitability among hospitals in the Republic of Korea. Factors that have been shown to be related to hospital profitability have not yet been systematically reviewed. The purpose of this study was to compile and summarize published works investigating the factors associated with hospital profitability in the Republic of Korea. We searched Research Information Sharing Service, Korea studies Information Service System, Database Periodical Information Academic, Korean Medical Database, KoreaMed, and Google Scholar from 1980 to November 2013. In addition, we manually searched reference lists from eligible studies. Review of 20 peer-reviewed articles revealed that very few of the variables employed in the eligible studies exerted consistent association with profitability, with the exception of personal cost (i.e., employee salaries). Future studies should take our findings into consideration before conducting research on hospital profitability.

• 음성과학
• /
• 제7권4호
• /
• pp.149-167
• /
• 2000

The purpose of this paper is to review the contribution made by some phoneticians including Si-gyung Chu, Du-bong Kim, Hyun-bae Choi, and Geuk-ro Lee in the early 20th century. It is known that the period can be characterized as the coexistence of traditional phonetics and modem phonetics. Si-gyung Chu well recognized the physical nature of speech sounds from the physiological point of view. Although Du-bong Kim adapted Chu's approach in some ways, he made some more detailed modifications in explaining the vocal organs. Hyun-bae Choi tried to explain the consonants and vowels systematically based on Western theories of phonetics. Finally, Geuk-ro Lee made the most significant contribution by introducing the experimental phonetics.

• Genomics & Informatics
• /
• 제2권1호
• /
• pp.7-18
• /
• 2004

Integrated genomics refers to the use of large-scale, systematically collected data from various sources to address biological and biomedical problems. A critical ingredient to a successful research program in integrated genomics is the establishment of an effective computational infrastructure. In this review, we suggest that the computational infrastructure challenges include developing tools for heterogeneous data organization and access, innovating techniques for combining the results of different analyses, and establishing a theoretical framework for integrating biological and quantitative models. For each of the three areas - data integration, analyses integration, and model integration - we review some of the current progress and suggest new topics of research. We argue that the primary computational challenges lie in developing sound theoretical foundations for understanding the genome rather than simply the development of algorithms and programs.

• Biomaterials and Biomechanics in Bioengineering
• /
• 제2권3호
• /
• pp.185-196
• /
• 2015

Titanium (Ti) based alloys are widely used in biomedical implants due to their low density, excellent corrosion resistance and good biocompatibilities. In recent years, growing interest in sever plastic deformation (SPD) has stimulated research and development on the techniques to attain refining of the grain size to the submicrometer or even nanometer level. The mechanical and wear properties determining the application of Ti in medicine may be improved via SPD. High pressure torsion (HPT) technique is one of the approaches available for improving the mechanical and wear properties of biomedical Ti materials. Accordingly, this article is designed to examine most recent state of the art scientific works related to the developments in mechanical properties and wear resistance of biomedical Ti materials processed by HPT. A comprehensive review in this area is systematically presented.

• International Journal of Advanced Culture Technology
• /
• 제10권4호
• /
• pp.23-244
• /
• 2022

The Pulpose of this systematic review is aimed to establish the procedure of the injection with saftey and efficiency in the pre-hospital cardiac arrest patient performing the cardiopulmonary resuscitation (CPR), compared with traditional medication administration using Ampoule and medication administration with Prefilled Syringe. Databases were searched for CPR, heart arrest, resuscitation, Pre-filled Syringe, and Ampoule by the electronic data research including Pubmed, EMBASE and Cochran Library of Konyang University Library: 4 articles were selected by three co-authors using EndNote X20 and Covidence (Covidence.org) and were systematically reviewed. The Result of this study, the medication administration using Pre-fillled Syringe improves the safety of patients and Emergency medical workers by reducing the error in administration dose and administering the drug in safe than the medication adminisrtaion using Ampoule, also, contributes to the increment of survival rate of cardiac arrest and severe patients by decreasing the administration time that prevents the delay of medication administration.

• Nuclear Engineering and Technology
• /
• 제54권12호
• /
• pp.4393-4411
• /
• 2022

In recent years, beryllium oxide has been widely utilized in multiple compact nuclear reactors as the neutron moderator, the neutron reflector or the matrix material with dispersed nuclear fuels due to its prominent properties. In the past 70 years, beryllium oxide has been studied extensively, but rarely been systematically organized. This article provides a systematic review of the application history, thermal properties, mechanical properties, corrosion behavior and fabrication methods of beryllium oxide. Data from previous literature are extracted and sorted out, and all of these original data are attached as the supplementary material, so that subsequent researchers can utilize this paper as a database for beryllium oxide research in reactor design or simulation analysis, etc. In addition, this review article also attempts to point out the insufficiency of research on beryllium oxide, and the possible key research areas about beryllium oxide in the future.