• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.3
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• pp.1311-1317
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• 2014

This is a descriptive study that attempts to provide basic information for easing job strain and enhancing the efficiency of cosmetology industry workers by examining the effects that the emotional labor and stress-coping of cosmetology workers have on their job strain. As a result of a multiple regression analysis of the factors affecting the subjects job strain, their surface acting and problem-focused coping, unconcern coping, social support were seen as factors that accounted for 30% of their job strain. Of the emotional labor of the subjects, the external behaviors displayed positive correlations with job strain; and they showed negative correlations with problem-focused coping and social support. Concerning emotional labor, sincere behavior was found to have positive correlations with problem-focused coping, hoping, social support, positive coping and strain relieving. Based on the results of this study, it is deemed that, along with interventions for emotional labor, education and intervention programs for a healthy and positive stress coping are needed in regards to interventions for cosmetology professionals.

• Journal of Pharmaceutical Investigation
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• v.38 no.1
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• pp.63-72
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• 2008

Meloxicam-loaded microspheres were prepared with poly(D,L-lactic acid)(PLA) by a solvent-emulsion evaporation method. The morphology, particle size, drug loading capacity, drug entrapment efficiency (EE) and release patterns of drug were investigated in vitro. Various batches of micro spheres with different size and drug content were obtained by changing the ratio of meloxicam to $PLA^{\circ}{\AE}s$ with different molecular weight, PLA concentration in the dispersed phase and stirring rate. Meloxicam crystals on microsphere surface, which were released rapidly and could act as a loading dose, were observed with increasing drug content. The release rate was increased with increase in drug contents and decrease in the molecular weight of PLA. Microspheres prepared with smaller molecular weight produced faster drug release rate. The release rate of meloxicam for long-acting injectable delivery system in vitro, which would aid in predicting in vivo release profile, could be controlled by properly optimizing various factors affecting characteristics of microspheres. Blood concentration-time profile of meloxicam after intramuscular injection of meloxicam-loaded microspheres in rabbits showed possibility of long term application of this system in clinical settings.

• Biomolecules & Therapeutics
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• v.19 no.1
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• pp.65-69
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• 2011

In this study, we investigated whether ambroxol significantly affects secretion, production and gene expression of mucin from cultured airway epithelial cells. Confluent primary rat tracheal surface epithelial (RTSE) cells were pretreated with adenosine triphosphate (ATP) for 5 min and then treated for 30 min with ambroxol to assess the effect on mucin secretion using ELISA. Additionally, confluent NCI-H292 cells were pretreated with ambroxol for 30 min and then stimulated with EGF or PMA for 24 h. The MUC5AC mucin gene expression and mucin protein production were measured by RT-PCR and ELISA. The results were as follows: (1) ambroxol did not significantly affect ATP-induced mucin secretion from cultured RTSE cells; (2) ambroxol inhibited the production of MUC5AC mucin protein induced by EGF and PMA in NCI-H292 cells; (3) ambroxol also inhibited the expression of MUC5AC mucin gene induced by EGF and PMA in NCI-H292 cells. This result suggests that ambroxol can inhibit the production and gene expression of MUC5AC mucin, by directly acting on human airway epithelial cells.

• Membrane Journal
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• v.25 no.3
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• pp.276-286
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• 2015

The effects of relaxation and backwashing on fouling in ultrafiltration were investigated using full-scale membrane bioreactors (MBRs) which operated at a constant flux of 30 LMH. This paper also estimated the feasibility of using intermittent aeration strategies for minimizing the hydraulic resistance to filtration in comparison with the continuous aeration for running MBRs. Multiple cycles of filtration (14.5 min each) and relaxation (0.5 min each) were repeated. Similarly, a backwash was conducted by replacing a relaxation after each filtration cycle for the comparative performance test. The attached cake thickness on the membrane rapidly increased, caused by subsequent no aeration leading to easier combining with gel layer and the formation of heterogeneous layer on the membrane surface. During periodic backwashing, it is expected that gel and thin cake layer might sufficiently be removed by heterogeneous layer. After periodic backwashing, subsequent cake layer formation during time of no aeration was rapid than frequent no aeration, acting as a prefilter and preventing further irreversible fouling. Based on the Pearson correlation analysis, overall period fouling (dTMP/min) and average of all cycles (dTMP/min) were strongly correlated with the on-off period of aeration for operating MBRs.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.25 no.6
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• pp.405-411
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• 2013

A sediment transport calculation considering cohesive force is proposed to deal with the transport phenomena of cohesive sediment. In the proposed calculation, each sand particle is assumed to be surrounded by a thin layer of mud. The critical Shields parameter and bed-load sediment transport rate are modified to include the cohesive force acting on the sand particle. The proposed calculation is incorporated into a two-way coupled fluid-structure-sediment interaction model, and applied to wave-induced topographic change of artificial shallows. Numerical results show that an increase in the content ratio of the mud, cohesive resistance force per unit surface area and water content cause increases in the critical Shields parameter and decreases in the bed-load sediment transport rate, reducing the topographic change of the shallow without changing its trend. This suggests that mixing mud in the pores of the sand particles can reduce the topographic change of shallows.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.13 no.2
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• pp.257-270
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• 2000

The objective of this study is to develop a damage model based on damage mechanics that can be used to analyze the mechanical behavior of structures with defects and the global behavior of damaged structures. A modified second order damage tensor that can be applied to finite element analysis is used to reflect the effect of damage. The damage stress computed from the effective stress is considered as an additional loading term acting on nodes and can represent the effect of crack surface. The accuracy of the proposed algorithm is verified by comparing the analysis results with the experimental data from other studies and the analysis results based on transverse isotropic theory. The developed damage model is applied to the analyses of structures with cracks under linear elastic condition. The comparisons confirmed that the quantitative analysis of the structural behavior due to crack orientation and multiple sets of cracks is possible. Also, the damage caused by rock excavation and fault zone is analyzed. The results also showed that the developed model can effectively analyze the global behavior of damaged structures.

• Korean Journal of Optics and Photonics
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• v.17 no.3
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• pp.290-295
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• 2006

The coupling between copper wire and a THz electromagnetic wave is one of the important factors to build up the magnitude and spectrum of a THz wave. We measured a I THz spectrum range THz pulse into a $480{\mu}m$ diameter and 23cm long copper wire waveguide. We measured THz pulses up to $275{\mu}m$ air gap between the end of the copper wire and transmitter or receiver chips. The coupling sensitivity of the transmitter is 3 times bigger than that of the receiver. The THz pulses propagated to air by the end of the receiver-side copper wire tip acting as a transmitter antenna. We confirmed that the THz field concentrates near the copper wire surface by opening the pin hole to the copper wire waveguide.

• Journal of Pharmaceutical Investigation
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• v.41 no.3
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• pp.173-178
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• 2011

Injectable chitosan hydrogels have attracted great potential due to sustained-release property and safety. Here, palmityl-acylated glycol chitosan (Pal-GC) was used to generate physically cross-linked hydrogels by virtue of hydrophobic attraction of linear fatty carbons. Glycol chitosan was chemically modified with N-hydroxysuccinimide-activated palmitic acid in dimethylsulfoxide (DMSO) containing dimethylaminopyridine. Through a series of preparation steps of (i) dialysis with DMSO, (ii) addition of palmityl-acylated exendin-4 (Ex4-C16), and (iii) dialysis with water, Pal-GC was self-assembled to form physically cross-linked hydrogels entrapped with Ex4-C16. The Pal-GC derivative was analyzed by using 1H NMR, and the surface morphology of Pal-GC hydrogels formed was examined by scanning electron microscopy. Also, the hypoglycemic effect induced by Pal-GC hydrogels containing Ex4-C16 (250 nmol/kg) was evaluated in non-fasted type 2 diabetic db/db mice and compared with GC hydrogels containing native Ex4 at the same dose. Results showed that palmityl group was successfully conjugated with the amines of glycol chitosan, and that Pal-GC efficiently generated the hydrogels formation. Moreover, Pal-GC hydrogels containing Ex4-C16 was found to greatly prolong the hypoglycemia duration (~ 4 days). This was due to the dual-functions of the palmityl groups present in both GC and exendin-4 such as hydrophobic attraction and plasma albumin-binding. We consider this new type of self-assembled GC hydrogels loaded with Ex4-C16 would be a promising long-acting sustained-release system with anti-diabetic property.

• Magazine of the Korean Society of Agricultural Engineers
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• v.18 no.4
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• pp.4218-4225
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• 1976

To insure the safety of the drainage sluice, topogrophical change due to erosion as well as capability of discharging the design flow in a very important factor. In consideration of the fact that the drainage sluice is built in the sea, its construction has many topographically restricted problems and naturally requires a completeness of research and experiment. This thesis is a comparative and analytic study of discharging flow acting on the erosion at the bottom of the structure on the basis of the measured velocity on the downstream channel of the drainage sluice. (1) The measured velocity shows a little higher values than the computed velocity, because the measured velocity was observed at the surface of the stream. There fore, it is reasonable that the compated velocity should be taken in this study. (2) The field observation was conducted to have the measurement of the flow velocity without surveying the area of flow. Therefore, the coefficient of discharge could not be computed. The survey of the area of flow is planned to be conducted along with the measurement of the flow velocity. (3) The apron of the drainage sluice is free discharging type and it was designed to be about 80m in length less than it should be. (4) The apron of free flow discharging type should have a solid foundation to protect the structure by preventing erosion damage to upstream and downstream channels against weathering of rock and strong torrent. Whether free flow discharging type or energy-dissipating type is best chosen depends on the topographical condition of the forage site, therefore, there would be a comparative study before the final decision was made about the protrection for the structure. (5) It is considered to be appropriate that the design and construction of the drainage sluice should have a complete study which is based on hydraulie model test before the type of protection is decided. (6) It is much requested that a variety of experiment equipments be installed and observed to study the protection for the drainage sluice.

• Journal of Ocean Engineering and Technology
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• v.25 no.5
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• pp.15-20
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• 2011

This study carried out a series of experiments involving impact tests (Drop Weight type & Charpy type with a standard specimen and newly designed I-type specimen), hardness tests, and fracture surface observations of French-made roll shell steel (F), abnormal roll shell steel (M), reheated roll shell steel (R), and S25C steel under heat treatment conditiAn experimental study was carried out to study the solid-liquid mixture upward hydraulic transport of solid particles in vertical and inclined annuli with a rotating inner cylinder. The lift forces acting on a fluidized particle play a central role in many important applications such as the removal of drill cuttings in horizontal drill holes, sand transport in fractured reservoirs, sediment transport, the cleaning of particles from surfaces, etc. In this study a clear acrylic pipe was used to observe the movement of solid particles. Annular velocities varied from 0.4 to 1.2 m/s. The effect of the annulus inclination and drill pipe rotation on the carrying capacity of a drilling fluid, particle rising velocity, and pressure drop in a slim hole annulus were measured for fully-developed flows of water and aqueous solutions of CMC (sodium carboxymethyl cellulose) and bentonite. The rotation of the inner cylinder was efficient at carrying particles to some degree. For a higher particle volume concentration, the hydraulic pressure loss of the mixture flow increased because of the friction between the wall and solids or between solids.