• Imaging Science in Dentistry
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• 제50권3호
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• pp.183-192
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• 2020

Purpose: This study was performed to assess the accuracy of preoperative cone-beam computed tomography (CBCT), when justified for other reasons, in locating the apical foramen and establishing the working length. Materials and Methods: Six electronic databases were searched for studies on this subject. All studies, of any type, were included if they compared measurements of working length with preoperative CBCT to measurements using an electronic apex locator (EAL) or histological reference standard. Due to the high levels of heterogeneity, an inverse-variance random-effects model was chosen, and weighted mean differences were obtained with 95% confidence intervals and P values. Results: Nine studies were included. Compared to a histological reference standard, CBCT indicated that the apical foramen was on average 0.40 mm coronal of its histological position, with a mean absolute difference of 0.48 mm. Comparisons were also performed to an EAL reference standard, but the conclusions could not be considered robust due to high levels of heterogeneity in the results. Conclusion: A low level of evidence is produced suggesting that preoperative CBCT shows the apical foramen to be on average 0.40 mm coronal to its histological position, with a mean absolute difference of 0.48 mm.

• 한국임상약학회지
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• 제19권1호
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• pp.61-64
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• 2009

The study was designed to compare the rate and extent of absorption of two enalapril tablets (10 mg), which has been widely used for the treatment of hypertension. This bioequivalence study was conducted using a standard preparation as reference and a generic as test in 24 male healthy volunteers. After an overnight fast, a single dose of the test or reference drugs were given with a washout period of 7 days. Heparinized blood samples were serially collected up to 10 hr. Plasma enalapril concentrations were quantified using a validated LC-MS/MS method. The data obtained for each subject was evaluated for $C_{max}$ and $AUC_{10hr}$ with respect to 90% confidence interval for log-transformed data. The 90% confidence intervals were log(0.9384)~log(1.1160) for $AUC_{10hr}$ and log(0.9482)~log(1.1474) for $C_{max}$. Thus, we concluded that the test and reference formulation are bioequivalent in terms of rate and extent of absorption.

• 한국IT서비스학회지
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• 제5권1호
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• pp.111-128
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• 2006

It was on the rise importantly to provide the efficient management process of the organization for dealing with the change about information and business management quickly and consistently. It was suggested with the architectural model on information technology to provide it in theoretically. The Federal Government and budget organization of the USA used it on actual business and the terms of EA (Enterprise Architecture) and are raising the efficiency of management. NCA (National Computerization Agency) of Korea published the book - "The Research about establishing ITA (Information Technology Architecture) and appling the standards". After being applied the model on MOGAHA (Ministry of Government Administration and Home Affairs) and MIC(Minisstry of Information and Communication), the concrete case was made. MOMAF (Ministry of Maritime Affairs and Fisheries) drove the leading model. The report ascertained the basic contents of ITA and researched the case of USA, MOGAHA, MIC, and tried to analyze the contents of appling maritime and fisheries area. The report contained the definition of purpose through analyzing environment and establishing the vision and the principles based on them. The report also contained the contents of architecture based on the standard of NCA - "The Government Standard Meta Model version 2.0" - and researched the MOMAF's Reference model using Government Reference model. The report established the investment architecture and the process of information technology asset management. It ascertained the characteristic of maritime & fisheries area and the subject of developing the MOMAF's ITA sustainably.

• Journal of Magnetics
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• 제21권4호
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• pp.603-615
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• 2016

In this study, in order to determine the validity and accuracy of MR imaging of 3D gradient dual echo 2-point DIXON technique for measuring abdominal adipose tissue volume and distribution, the measurements obtained by CT were set as a reference for comparison and their correlations were evaluated. CT and MRI scans were performed on each subject (17 healthy male volunteers who were fully informed about this study) to measure abdominal adipose tissue volume. Two skilled investigators individually observed the images acquired by CT and MRI in an independent environment, and directly separated the total volume using region-based thresholding segmentation method, and based on this, the total adipose tissue volume, subcutaneous adipose tissue volume and visceral adipose tissue volume were respectively measured. The correlation of the adipose tissue volume measurements with respect to the observer was examined using the Spearman test and the inter-observer agreement was evaluated using the intra-class correlation test. The correlation of the adipose tissue volume measurements by CT and MRI imaging methods was examined by simple regression analysis. In addition, using the Bland-Altman plot, the degree of agreement between the two imaging methods was evaluated. All of the statistical analysis results showed highly statistically significant correlation (p<0.05) respectively from the results of each adipose tissue volume measurements. In conclusion, MR abdominal adipose volumetry using the technique of 3D gradient dual echo 2-point DIXON showed a very high level of concordance even when compared with the adipose tissue measuring method using CT as reference.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제13권5호
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• pp.2529-2543
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• 2019

Scanning electron microscopy (SEM) image can link with the microscopic world through reflecting interaction between electrons and materials. The SEM images are easily subject to blurring distortions during the imaging process. Inspired by the fact that dark channel prior captures the changes to blurred SEM images caused by the blur process, we propose a method to evaluate the SEM images sharpness based on the dark channel prior. A SEM image database is first established with mean opinion score collected as ground truth. For the quality assessment of the SEM image, the dark channel map is generated. Since blurring is typically characterized by the spread of edge, edge of dark channel map is extracted. Then noise is removed by an edge-preserving filter. Finally, the maximum gradient and the average gradient of image are combined to generate the final sharpness score. The experimental results on the SEM blurred image database show that the proposed algorithm outperforms both the existing state-of-the-art image sharpness metrics and the general-purpose no-reference quality metrics.

• 논리연구
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• 제19권3호
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• pp.341-368
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• 2016

"p이지만 나는 p라고 믿지 않는다"와 같은 문장은 어떤 상황에서도 자연스럽게 발화될 수 있을 것 같지 않고, 심지어는 부조리하고 모순되게 들리기까지 한다. 무어의 역설이 제기하는 문제는 왜 이런 문장이 아무런 형식적인 모순이 없음에도 불구하고 이를 발화하는 것이 부조리하게 들리는지를 설명하는 것이다. 무어의 역설에 대한 기존의 견해는 주로 믿음이나 주장(assertion)의 성격에서 그 부조리성의 근원을 찾으려 한다. 필자는 본 논문에서 기존의 견해들이 무어의 역설을 만족스럽게 설명하지 못함을 주장하고, 이에 대한 새로운 설명을 제안한다. 이 제안에 따르면 무어의 역설의 근원은 "자기-지시"에 있다. 자기-지시는 주체가 어떤 특정한 방식으로 믿음을 형성하는 성향에 의해 부분적으로 구성되는데, 무어의 역설은 주체가 자신을 "나"로 지시하는 동시에 어떤 사람을 "나"로 지시하기 위해 만족시켜야할 조건을 만족시키지 못하는 데에서 발생한다.

• 한국비블리아학회지
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• 제21권2호
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• pp.81-96
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• 2010

본 연구에서는 이용자 인식조사를 기반으로 하여 온라인 참고정보원용 메타데이터 항목을 제안하고 있다. 설문을 통해 4 관종의 사서들에게 17개 메타데이터 각각의 항목에 대한 필요성에 대해서 물었다. 또한 지난 2년 동안 운영되어온 시스템에의 메타데이터 입력현황과 이용자 인식조사 결과를 비교하였다. 이용자 인식조사와 시스템 입력비율을 기반으로, 17개의 메타데이터 항목 중 정보원 제목, 설명, 주제분야, 출판사, 유형, 식별자, 언어, 범위, 소장위치, 태그 항목은 반드시 포함되어야 할 항목으로 최종적으로 제안할 수 있었다. 또한 제작자와 저작권의 데이터가 실제 시스템에 입력된 비율은 각각 20.20%, 18.30%였으나, 설문응답자들은 각각 82.15%, 82.77%로 이 항목이 필요하다고 응답하였다. 따라서 이 두 개의 항목도 포함시키는 것이 적합하다고 본다. 다만, 시스템에의 입력비율이 3% 이하였던 형태, 원정보원, 날짜, 관련정보원, 기여자 항목에 대해 설문응답자의 거의 70% 이상이 이 모든 항목이 필요하다고 응답하였으므로 이에 대해서는 추가적인 연구가 진행되어야 한다고 본다.

• 기술혁신연구
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• 제11권1호
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• pp.1-27
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• 2003

In the knowledge-based economy, technology valuation of patents, brand name, know-how is presented for as key subject of intangible assets management science. This paper reviews the methods of technology valuation that have been developed by valuation specialists. Also, is talking about the practical application by income approach (DCF) method. The function and role of technology valuation analysts such as the related organizations and the reference of foreign organization is appeared through the examples.

• 대한수학회논문집
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• 제28권1호
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• pp.177-181
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• 2013

In this note, we consider a curved tube with varying cross-section formed by rotating open bounded Euclidean domains with respect to a reference curve, and successfully give a lower bound to the threshold of the Laplacian on the tube, subject to Dirichlet boundary conditions on the surface and Neumann conditions at the ends of the tube. This generalizes the corresponding result in [1].

• Communications for Statistical Applications and Methods
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• 제6권2호
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• pp.601-610
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• 1999

Crossover design is officially except for special occasions recommended by KFDA and FDA for assessing Bioequivalence between two drugs one for reference and the other for innovator. Such design is regarded as a special case of latin square split-polt or repeated measurement design and its main difference with other designing methods is that each subject in an experiment is exposed two drugs in sequence. Therefore general statistical analysis is not suitable since the model for this experiment includes carryover effect in addition to period and sequence effect. in this paper analysis for crossover model with two drugs and its interpretation are mainly discussed and an example is given for illustration.