• Journal of Korea Spatial Information System Society
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• v.2 no.2 s.4
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• pp.59-74
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• 2000

Because efficiency of the 1st-phase NGIS investment(1995-2000) has not been clearly measured, the action taken in the 2nd-phase NGIS project requires NGIS budgets to be evaluated in terms of effectiveness. Especially, the effective investments in local governments are critical for the NGIS projects, because they execute the much larger amount of budgets in total than other GIS projects. As indicated, for the successful NGIS implementation, it is important to obtain continuous political and financial supports from decision makers. As a persuasion measure for the budget appropriation, CBA(Cost-Benefit Analysis) and CEA(Cost-Efficiency Analysis) can play an important role for the decision makers. The major concern of this paper is how to measure the costs and benefits of the GIS implementation by considering important characteristics of the GIS projects in local governments, and existing theories are reviewed for this concern. The GISs in local governments can have different stages in terms of its evolution and the effectiveness of the applications can be represented variously. To identify categories for measuring costs and benefits of the various GISs, case studies and success stories are reviewed from both the foreign and domestic research. The categories of costs and benefits are determined from the tangible and intangible aspects. The categories for the quantitative and qualitative measure are proposed to evaluate the GISs in local governments. After measuring costs and benefits, three key evaluation methods in cost-benefit analysis are suggested as follows: 1) the benefit: cost ratio (B/C), 2) Internal Rate of Return (IRR), and 3) the net present values (NPV) of the costs and benefits. The sensitivity and uncertainty analysis are also helpful to make a decision for the GIS budget appropriation in local governments. In conclusion, although cost-benefit analysis is not an easy undertaking, it is certain that it can play an important role in the future for the GIS funding decisions in local governments.

• Journal of Gifted/Talented Education
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• v.26 no.2
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• pp.235-255
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• 2016

This study examined whether there were differences in stakeholders' concerns regarding consulting in gifted education institutes. A total of 122 stakeholders in gifted and talented education responded to SoCQ(the Stage of Concerns Questionnaire, Hall & Hord, 2011). The SoCQ responses of these stakeholders to consulting for gifted education institutes were converted into relative intensities and SoCQ profiles, which were analyzed by the affiliated areas of institute, teaching years in gifted education, continuities of affairs in gifted education, and approaches to teacher training for gifted education with using t-test and one-way analysis of variance. Results indicated that stakeholders generally showed the highest concern for stage 1(information) and the lowest concerns for stage 4(consequence), which were the initial stage of change and innovation in consulting for gifted education institutes. In the meanwhile, skakeholders having training program for professionals showed the more concern for stage 6(refocusing), which was a kind of resistance for the present consulting for gifted education institutes. On the based on these results, this study suggested ways(or methods) for settlement and the diffusion of successful gifted education consulting.

• Korean Security Journal
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• no.45
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• pp.161-189
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• 2015

As the terrorist act inflicted on the American Ambassador to Korea, Mark Lippert on March 5, 2015, the hunting rifle case in Sejong-si in which 3 persons were killed on February 25, and the hunting rifle murder case in Hwaseong-si Namyang-dong on February 27 occurred in succession, there is growing concern that our country is no long safe from firearm violence. Internationally, there is growing concern that our country is no longer safe from international terrorist organizations such as Islamic State (IS), the Sunni Muslims fundamentalists' Islamic militia group, which an 18-year old Korean boy Kim voluntarily joined in January 2015. The police crisis negotiation of our country was established and operated to prepare for the 1988 Olympic Games mainly for counter-terrorism purposes, and due to the characteristics of the prohibition of the use of guns, not a counter-terrorism incident has occurred, so the skepticism about its existence and the development directions are actively being discussed. Our country still prefers the traditional use of force such as SWAT team to resolve crisis case, such as such as murder, terrorism, robbery, and is reinforcing tactical capabilities. However, to perform the primary mission of the police to protect the people's lives and properties, it is necessary to establish the system in which crisis negotiations are possible in the initial stages no matter what incidents may occur by expanding the education for crisis negotiations techniques which are emphasized in the advanced countries such as the United States. In this research, the police department's internal education materials and media are analyzed so that the new police officers who work hardest on the forefront can carry out the roles as basic negotiators of crisis negotiations, and the measures for the development directions of the police crisis negotiations are presented.

• Bulletin of the Society of Naval Architects of Korea
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• v.26 no.3
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• pp.9-20
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• 1989

It is important to enhance the safety of ship structures as much as possible in order to prevent the disastrous collapse of structures. In fact, the strength problem of structures is closely related with the safety problem of structures. Recently, the direct calculation method using a rational approach based on the first principle is implemented into the structural design process instead of adopting empirical approach based on the rules. The structural designer have shown increased concern with the problem of adequacy of conventional design method based on the safety factor since it does not fully take into account some degree of variability of the applied loads on and the strength of ship structures. To deal with the analysis of structures effectively, it is necessary to have three stages being equally treated. The first one is load analysis, second one response analysis, third one safety analysis. For marine structures, most of research effort has been however put into the first and second stages. The third stage is normally done by simple procedures. Hence, the various probabilistic methods are compared in order to establish the reliability analysis techniques for ship structures. As a result, the advanced level 2 method is selected as a most effective and accurate reliability method. The validity of this method is further demonstrated by comparing the results with the conventional method for the problem of the longitudinal strength of hull girder of Ro-Ro ship.

• Journal of Korean Society of Environmental Engineers
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• v.39 no.9
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• pp.527-533
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• 2017

Environmental concern about smart phone is growing because it has short product life span while having intensive production technology and cost. In this study environmental impact of the smart phone is quantified using the LCA methodology based on the ISO 14040 series standards. The assessment considers potential environmental impacts across the whole life cycle of the smart phone including; pre-manufacturing; manufacturing; distribution; product use; and end-of-life stages. The pre-manufacturing stage is the most dominant life cycle stage causing the highest environmental impacts among all 10 impact categories assessed. The global warming impacts of the smart phone in the pre-manufacturing, distribution, use, manufacturing, and end-of-life stages were 52.6% 23.9%, 15.7%, 7.0%, and 0.8%, respectively. Sensitivity of the life cycle impact assessment results to the system boundary definition and assumptions made were quite high. Three components of the smart phone, PCB, battery, and display module were identified as the key components causing majority of the potential environmental impact in the pre-manufacturing stage. As such the slim and light-weight design and the use of environmental friendly materials are important design factors for reducing the environmental impact of the smart phone.

• Korean Journal of Clinical Laboratory Science
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• v.54 no.4
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• pp.249-255
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• 2022

Alzheimer's disease (AD) represents a major public health concern and has been identified as a research priority. Clinical research evidence supports that the core cerebrospinal fluid (CSF) biomarkers for AD, including amyloid-β (Aβ42), total tau (T-tau), and phosphorylated tau (P-tau), reflect key elements of AD pathophysiology. Nevertheless, advances in the clinical identification of new indicators will be critical not only for the discovery of sensitive, specific, and reliable biomarkers of preclinical AD pathology, but also for the development of tests that facilitate the early detection and differential diagnosis of dementia and disease progression monitoring. The early detection of AD in its presymptomatic stages would represent a great opportunity for earlier therapeutic intervention. The chance of successful treatment would be increased since interventions would be performed before extensive synaptic damage and neuronal loss would have occurred. In this study, the importance of developing an early diagnostic method using cognitive decline biomarkers that can discriminate between normal, mild cognitive impairment (MCI), and AD preclinical stages has been emphasized.

• Computers and Concrete
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• v.8 no.2
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• pp.193-206
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• 2011

The use of Carbon Fiber Reinforced Polymers (CFRP) to strengthen reinforced concrete beams under bending and shear has gained rapid growth in recent years. The performance of shear strengthened beams with externally bonded CFRP laminate or fabric strips is raising many concerns when the beam is loaded under cyclic loading. Such concerns warrant experimental, analytical and numerical investigation of such beams under cyclic loading. To date, limited investigations have been carried out to address this concern. This paper presents a numerical investigation by developing a nonlinear finite element (FE) model to study the response of a cantilever reinforced concrete T-beam strengthened in shear with side bonded CFRP fabric strips and subjected to cyclic loading. A detailed 3D nonlinear finite element model that takes into account the orthotropic nature of the polymer's fibers is developed. In order to simulate the bond between the CFRP sheets and concrete, a layer having the material properties of the adhesive epoxy resin is introduced in the model as an interface between the CFRP sheets and concrete surface. Appropriate numerical modeling strategies were used and the response envelope and the load-displacement hysteresis loops of the FE model were compared with the experimental response at all stages of the cyclic loading. It is observed that the responses of the FE beam model are in good agreement with those of the experimental test. A parametric study was conducted using the validated FE model to investigate the effect of spacing between CFRP sheets, number of CFRP layers, and fiber orientation on the overall performance of the T-beam. It is concluded that successful FE modeling provides a practical and economical tool to investigate the behavior of such strengthened beams when subjected to cyclic loading.

• The Journal of the Korean dental association
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• v.54 no.6
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• pp.429-437
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• 2016

Objectives: Photodynamic therapy has been proven to promote additional clinical and microbiological benefits in the treatment of chronic periodontitis and aggressive periodontitis. The purpose of this study is to assess the effectiveness of the photodynamic therapy for patient with periodontitis. Methods: We searched the eight Korean databases and Ovid-MEDLINE, Ovid-EMBASE, Cochrane Library. Total 300 studies were searched and 13 studies were included in the final assessment. Each of the stages from literature search and extraction of data were carried out independently by 2 researchers. We used tools of Scottish Intercollegiate Guidelines Networks for assessment of the quality of studies. Results: The safety of the photodynamic therapy was assessed by bleeding. The effectiveness of the photodynamic therapy was assessed by the reduction of Probing pocket depth (PPD) and the gain of Clinical attachment level (CAL). The mean difference of PPD was 0.46(95% CI 0.09~0.82), (p=.01).). The mean difference of CAL was ?0.49(95% CI ?1.12~0.14), (p=.13). Conclusion: The additional use of $^{\circ}{\infty}$Antimicrobial Photodynamic Therapy for Periodontitis$^{\circ}{\pm}$ caused hemorrhage to similar extents to conventional treatment modalities, where scaling and root planing are solely performed, in patients with periodontitis who are expected to have a lower degree of treatment response to non-surgical or surgical periodontal therapies (implant or refractory periodontitis) and those where there is a concern for the possible occurrence of antimicrobial side effects or resistance. This indicates that there are no problems with its safety. But there were no consistent reports about the effects of the additional use of photodynamic therapy. This led to a decision that the safety and efficacy of the current technology deserve further studies (Recommendation rating of A, Classification of technology II-a).

• IMMUNE NETWORK
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• v.22 no.6
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• pp.48.1-48.13
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• 2022

With the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, which are randomly mutated, the dominant strains in regions are changing globally. The development of preclinical animal models is imperative to validate vaccines and therapeutics against SARS-CoV-2 variants. The objective of this study was to develop a non-human primate (NHP) model for SARS-CoV-2 Delta variant infection. Cynomolgus macaques infected with Delta variants showed infectious viruses and viral RNA in the upper (nasal and throat) and lower respiratory (lung) tracts during the acute phase of infection. After 3 days of infection, lesions consistent with diffuse alveolar damage were observed in the lungs. For cellular immune responses, all macaques displayed transient lymphopenia and neutrophilia in the early stages of infection. SARS-CoV-2 Delta variant spike protein-specific IgM, IgG, and IgA levels were significantly increased in the plasma of these animals 14 days after infection. This new NHP Delta variant infection model can be used for comparative analysis of the difference in severity between SARS-CoV-2 variants of concern and may be useful in the efficacy evaluation of vaccines and universal therapeutic drugs for mutations.

• Journal of Korean Academy of Nursing
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• v.30 no.4
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• pp.1018-1034
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• 2000

The purpose of this study was to construct model of sexual adjustment in people with spinal cord injury and to determine factors that relate to sexual adjustment using methodological triangulation. A total of 134 persons who were registered members of spinal cord injury organization and admitted rehabilitation unit in the hospital were included in the study. Participants answered questionnaire concerning importance of life events, sexual concern, sexual adjustment. Qualitative data were collected through semi-structured indepth interviews from 10 individuals with spinal cord injury who were previously included in the quantitative study. Constant compatative method was used to analyze the data. The results were as follows : 1) With respect to eleven other areas of life, sex life ranked the sixth and economic status ranked the highest in terms of importance. However social life ranked the lowest among the 11areas. 2) Among seven topics related to sexuality were methods and techniques to achieve sexual satisfaction, and helping a partner cope emotionally with limitation on sexual dysfunction was the second greastest. 3) The mean score for sexual adjustment was 19.47 which can be considered. 4) A process on how individuals with spinal cord injury adjust to their changed sexual life immerged from the qualitative data. It includs 4 stages: 'stage of loss' 'stage of endeavoring' 'stage of effort' and 'stage of adjustment'. Categories showing context for the action/interaction strategies were 'steadiness' and 'rediscovery as a sexual being'. There were three factors which may stimulate the adjustment process while the others may interrupt it. Those factors included personal matters, family matters and social matters. The individuals may follow each stage step by step but may go back to the previous step depending on the outcomes of their adjustment. 5) There were three factors which may stimulate the adjustment process while the others may interrupt it. Those factors included personal matters, family matters and social matters.