• Title/Summary/Keyword: sport effect

Search Result 724, Processing Time 0.027 seconds

Gintonin facilitates catecholamine secretion from the perfused adrenal medulla

  • Na, Seung-Yeol;Kim, Ki-Hwan;Choi, Mi-Sung;Ha, Kang-Su;Lim, Dong-Yoon
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.20 no.6
    • /
    • pp.629-639
    • /
    • 2016
  • The present study was designed to investigate the characteristics of gintonin, one of components isolated from Korean Ginseng on secretion of catecholamines (CA) from the isolated perfused model of rat adrenal gland and to clarify its mechanism of action. Gintonin (1 to $30{\mu}g/ml$), perfused into an adrenal vein, markedly increased the CA secretion from the perfused rat adrenal medulla in a dose-dependent fashion. The gintonin-evoked CA secretion was greatly inhibited in the presence of chlorisondamine ($1{\mu}M$, an autonomic ganglionic bloker), pirenzepine ($2{\mu}M$, a muscarinic $M_1$ receptor antagonist), Ki14625 ($10{\mu}M$, an $LPA_{1/3}$ receptor antagonist), amiloride (1 mM, an inhibitor of $Na^+/Ca^{2+}$ exchanger), a nicardipine ($1{\mu}M$, a voltage-dependent $Ca^{2+}$ channel blocker), TMB-8 ($1{\mu}M$, an intracellular $Ca^{2+}$ antagonist), and perfusion of $Ca^{2+}$-free Krebs solution with 5mM EGTA (a $Ca^{2+}$chelater), while was not affected by sodium nitroprusside ($100{\mu}M$, a nitrosovasodialtor). Interestingly, LPA ($0.3{\sim}3{\mu}M$, an LPA receptor agonist) also dose-dependently enhanced the CA secretion from the adrenal medulla, but this facilitatory effect of LPA was greatly inhibited in the presence of Ki 14625 ($10{\mu}M$). Moreover, acetylcholine (AC)-evoked CA secretion was greatly potentiated during the perfusion of gintonin ($3{\mu}g/ml$). Taken together, these results demonstrate the first evidence that gintonin increases the CA secretion from the perfused rat adrenal medulla in a dose-dependent fashion. This facilitatory effect of gintonin seems to be associated with activation of LPA- and cholinergic-receptors, which are relevant to the cytoplasmic $Ca^{2+}$ increase by stimulation of the $Ca^{2+}$ influx as well as by the inhibition of $Ca^{2+}$ uptake into the cytoplasmic $Ca^{2+}$ stores, without the increased nitric oxide (NO). Based on these results, it is thought that gintonin, one of ginseng components, can elevate the CA secretion from adrenal medulla by regulating the $Ca^{2+}$ mobilization for exocytosis, suggesting facilitation of cardiovascular system. Also, these findings show that gintonin might be at least one of ginseng-induced hypertensive components.

A Review : On Exercise Performance Induction Gene Factors Change (운동이 유전자 조절물질에 미치는 영향에 관한 고찰)

  • Um, Ki-Mai;Yang, Yoon-Kwon;Kim, Tae-Woo
    • Journal of Korean Physical Therapy Science
    • /
    • v.8 no.1
    • /
    • pp.745-758
    • /
    • 2001
  • The purpose of study to phenomenological examine and the mechanism regarding the gene(DNA, RNA, Protein) and sports to studied, analyzed. and evaluated. This review considers the evidence for genetic effects in several determinants of endurance performance and resistance performance, namely: body measurements and physique, body fat pulmonary functions, cardiac and circulatory functions, muscle characteristics. substrate utilization, maximal aerobic power and other. Moreover, the response to aerobic training of indicators aerobic work metabolism and endurance performance is reviewed, with emphasis on the specificity of the response and the individual differences observed in training ability. This study indicate that improvement of 'Enhancer Action' in RNA genes changed by exercise or sports. Moreover exercise was effect on Central Dogma with DNA makes RNA makes Protein. and think that occurred with exercise influence on skeletal muscle into cell have to Myosin Heavy Chain (MHC) changed was after exercise performance, which accompanied into skeletal muscle that were exercise-induces gene-modulation that is, take gene mutations. This study known that existed hormone(epinephrine)-immune system with interaction. Exercise were altered insulin binding and MAP Kinase signaling increased into immune cells. This review suggested that the high rate of glutamine utilization by cells of the immune system serves to maintain a high intra cellular concentration of the intermediates of biosynthetic pathways such that optimal rates of DNA, RNA and protein synthesis can be maintained. In the absence of glutamine, lymphocytes do not proliferate in vitro: proliferation increase greatly as the glutamine concentration increase. Glutamine is synthesized in skeletal muscle. Skeletal muscle and plasma glutamine levels are lowered by sepsis, injury, bums, surgery and endurance exercise and in the overtrained athlete. The study of result show that production of ET-1 is markedly increased tissue specifically in the heart by exercise without appreciable changes in endothelin-converting enzyme and endothelial receptor expressions, suggest that myocardial ET-1 may participate in modulation of cardiac function during exercise. Conclusionally, this study indicate that improvement of 'Enhancer Action' in RNA genes changed by exercise or sports. Moreover exercise was effect on Central Dogma with DNA makes RNA makes Protein. This study is expected to contribute the area of sports science, medicine, hereafter more effort is required to establish the relation between gene alters and exercise amount.

  • PDF

Effect of Arousal Control Training Conjugated Heart Rate Biofeedback for National Substitute Archery Players (심박수 바이오피드백기법을 활용한 국가대표 후보 양궁선수의 각성조절훈련 효과 분석)

  • Hong, Seong-Taek
    • The Journal of the Korea Contents Association
    • /
    • v.11 no.9
    • /
    • pp.469-484
    • /
    • 2011
  • The purpose of this study was to examine the effect of arousal control training conjugated heart rate biofeedback for national substitute three archery players. The arousal control training programs was developed on previous researches and 3 archery experts and 1 sport psychologist had meetings. The training programs contained as orientation, breathing regulation, progressive relaxation technique, heart rate biofeedback, cognitive restructuring, routine and consisted of 24 weeks. XCOACH was utilized as heart rate biofeedback instrument. The effects was examined on competitive state anxiety inventory-2, archery score and ranking, observation, interviews and self assessment. As the results, the score of subfactor was improved on somatic state anxiety, cognitive state anxiety and self-confidence. As the results of observation, interviews and self assessment, the ability of arousal control was enhanced by using effective psychological skills conjugated heart rate biofeedback.

An Impact Assessment on Atmospheric Dispersion of Pesticide using AGDISP Model (AGDISP모델을 이용한 농약의 대기확산 영향평가)

  • Kim, Jeong-Hwan;Koo, Youn-Seo;Lee, Seung-Hoon
    • Journal of Environmental Impact Assessment
    • /
    • v.22 no.6
    • /
    • pp.547-556
    • /
    • 2013
  • Recently, golf courses have increased over the years because golf became popular leisure sport. Various environmental problems have been then issued by a golf course during constructing and running them. A problem of pesticide, which is serious among various environmental problems, from golf course has harmful effect on surrounding area and makes human suffer from acute and chronic diseases. Pesticides are used for the cost-effective managing of golf course and the amount of pesticides also increases as the number of golf course increase. Since the assessment of pesticides on near-by surrounding has been focused on water and soil media, studies related to atmospheric dispersion have been hardly attempted. The method to assess an impact of pesticide nearby agricultural production by the atmospheric dispersion using AGDISP(AGricultural DISPersal) model was developed and applied to the actual planned golf course located in Hongcheon, Gangwon. For implementing AGDISP, parameters were investigated from the golf course's land use planning map, pesticide spray device, Hong-Cheon weather station and etc. First of all, a kind of pesticide, a form of spraying pesticide, geographical features, weather data, and distance(golf course to plantation) were investigated to understand how to work these parameters in AGDISP. Restricted data(slope angle, droplet size distribution and solar insolation) sensitivity analysis of these parameters to estimate effect of pesticide nearby a plantation and a high relative contribution data of analyzed data was selected for input data. Ethoprophos was chosen as the pesticide used in the golf course and the amounts of pesticide deposition per annual agricultural productions were predicted. The results show that maximum amount of pesticide deposition through atmospheric dispersion was predicted $2.32{\mu}/m^2$ at 96 m where the nearest organic plantation exists. The residues of pesticide were also estimated based on the annul production of the organic and the deposition amount of the pesticide. Consequently, buckwheat, wheat and millet were likely to exceed maximum residue limits for pesticides in foods(MRL) and sorghum, corn and peanut were likely to exceed MRL by organic farming as well.

The Relationship of Participant Motivation, Physical Self-concept, University Life Satisfaction of the Leisure Sport on the University Students (대학생 여가스포츠의 참여동기, 신체적자기개념, 대학생활만족과의 관계)

  • Lee, Gun-Chur
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.20 no.12
    • /
    • pp.357-366
    • /
    • 2019
  • The purpose of this study is to analyze the relationship between students' motivation for participating in leisure sports, students' physical self-concept and the life satisfaction of university students. A total of 419 students were finally analyzed using the convenience sampling method of non-random sampling method after selecting those university students participating in leisure sports at a university located in J district. The results of analysis using SPSS version 21.0 program are as follows. First, there is a positive (+) correlation between the motives of participation of university students and their physical self-concept and satisfaction with university life. Second, the influence of the motive to participate in sports has a positive (+) effect on sports competence and this is affected by health fitness and social interaction, physical activity is affected by pleasure, health fitness, and conditioning, self-esteem, muscular strength is affected by pleasure, health fitness, condition, and society, flexibility is affected by pleasure, health fitness, and society. Third, the influence of participation motive had a positive (+) effect on school satisfaction is affected by pleasure, health fitness, physical condition, external display, socialization, and fellow satisfaction is effected by pleasure and condition.

The Effect of Different Triathlon on Weight, Sodium and Hematological Changes (다른 거리의 철인 3종 경기 시 체중, 나트륨 및 혈액 성분에 미치는 영향)

  • Park, Chan-Ho;Kim, Tae-Un
    • Journal of Life Science
    • /
    • v.19 no.1
    • /
    • pp.46-51
    • /
    • 2009
  • This study examined how differing triathlon durations effect weight, serum sodium concentration, and hematological levels, and investigated relationships between these variables and finishing time as well as between body weight changes and serum sodium following Ironman distance triathlons (IDT) and Olympic distance triathlons (ODT). All eight athletes successfully completed ODT and IOT. We found that the mean body weight decreased following both IDT and ODT and that serum sodium was significantly (p<0.05) increased immediately after IDT, RBC, Hb, Hct, and MCH were significantly (p<0.05) increased immediately after IDT. Hct was significantly (p<0.05) decreased immediately after ODT. MCHC was significantly (p<0.01) increased immediate1y after ODT. In IDT, the percentage of change in body weight correlated to the percentage of change in serum sodium concentrations (r=0.75, p=0.05). In conclusion, our srudy showed that serum sodium concentraion increased in IDT and maintained in ODT, despite significant body weight loss during the races. The percentage of change in body weight was related to serum sodium concentration but unrelated to performance in the triathlon. The changes of RBC, Hb, and Hct values from two different length triathlons were depending on race distance.

Effects of Different Type of Exercise on Blood Variables and Leptin Hormones in SD Rats (훈련방법의 차이가 흰쥐의 혈액성분과 랩틴농도에 미치는 영향)

  • Jin, Young-Wan
    • Journal of Life Science
    • /
    • v.16 no.6
    • /
    • pp.960-963
    • /
    • 2006
  • The purpose of this study is to evaluate the different type of exercise training on the changes of blood variables and leptin in SD rats. For this study, SD rats were divided into three groups: control group (CG: n=10), swim trained group (SG: n=10), and treadmill trained group (TG: n=10). The animals were housed in a pathogen-free animal facility ($22-24^{\circ}C$, 50-60% relative humidity, 08:00-20:00 lighting hours) at D university animal center, Pusan, Korea). Food and water were available ad libitum. The trained rats underwent a 8-wk endurance swim training (5 times/wk) in water at $26-29^{\circ}C$ (SG) and treadmill training (5 times/wk) in DAEJONG treadmill for 60 min. All data were expressed as mean and standard deviation by using SPSS package program (ver 10.0). The result through the statistical analysis of this data were summarized as follows: 1. In the weight changes, there were significant differences among CG, SG and TG(p<.05) after regular swim and treadmill training. TG showed the lowest weight than the other groups. 2. In the epididymal & perirenal adipose tissue levels, there were significant differences among CG, SG and TG(p<.05) after regular swim and treadmill training. TG showed the lowest adipose tissue levels than the other groups. 3. In the triglyceride changes, For the SG and TG, there were significantly decreased after regular swim and treadmill training. TG showed the lowest triglyceride levels than the other groups. 4. In the insulin hormone, For the SG and TG, there were significantly decreased after regular swim and treadmill training. TG showed the lowest insulin levels than the other groups. 5. In the leptin changes, For the SG and TG, there were significantly decreased after regular swim and treadmill training. TG was the lowest than the other groups. Based on the results, Regular swim and treadmill training decrease body weight, epididymal & perirenal adipose tissue levels significantly, this is caused but by decreased triglycerides, insulin, and leptin hormone levels not by the other factors. Regular treadmill training decreased insulin hormone levels compare to swim training, however there was no direct insulin effect on the weight changes. and it might be the direct effect of leptin hormones.

Effect of Participation in Regular Leisure Sports on Satisfaction with Family Relationship in Adolescents (청소년의 규칙적인 여가스포츠 참여가 가족관계 만족도에 미치는 영향)

  • Cho, Hyungsun;Hwang, Sunhwan;Bang, Shinwoong
    • The Journal of the Korea Contents Association
    • /
    • v.15 no.11
    • /
    • pp.591-602
    • /
    • 2015
  • The purpose of this study was to examine the effect of participation in regular leisure sports on satisfaction with family relationship in adolescents. To achieve this purpose, 650 students of elementary and middle schools in Seoul and Gyeonggi area were selected and surveyed using the purposive sampling method. 611 survey samples were used in final analysis and 39 survey samples were excluded because of untrustworthy response. Statistical program AMOS 18.0 was used to conduct the confirmatory factor analysis and goodness of fit test, and SPSS 21.0 Window program was used to conduct analysis of frequency, t-test, and ANOVA. Through the analysis, the main findings were as follows; First, it was found that the adolescents participating in regular leisure sports has significant difference in satisfaction with family relationships compared to non-participation group. Second, satisfaction with family relationship of parental participation group in regular leisure sport was high the most followed by lonely participation group and non-participation group. Finally, authors described the implications and future studies.

New Fact and Experience About The Tennis Lesson Using Tool (도구를 활용한 테니스 교수법이 가져다준 새로운 사실과 경험)

  • Shin, Myoung-Jin;Shim, Yun-Sik
    • The Journal of the Korea Contents Association
    • /
    • v.12 no.11
    • /
    • pp.388-397
    • /
    • 2012
  • The tennis was one of the most popular sport in the general physical education lesson. However there are many problems such as difficult of improvement tennis skill, lack of class days and so many students in a class. These reasons could ultimately damage the overall quality of class. The purpose of this research was to beginner students was fun and easy to learn. The tennis lesson using tools were 1.selective hitting ball, 2. high net hitting ball, 3. hitting orange ball. Scores of the experimental group(n=23) and the control group(n=21) were compared. In order to verify course content was the same 15 weeks, conducted a tennis teaching methods to take advantage of the tools. And tools to take advantage of the students who participated in a class analysis of the qualitative data (interviews, documents, questionnaires, observations, journals). As a result, the satisfaction scores of the experimental group were higher than those of the control group. The tennis lesson using tools to take positive effect(meaning, improved skill, easy, fun/curious/confident) and negative effect(difficulties of adaptation, a high challenge level) was induced. In summary of the quantitative/qualitative data 'Orange Ball' has a positive impact on the girls than boys and teaching methods using tools gave generally positive influence to students.

The effect of applying u-health system on metabolic syndrome management of elderly (U-health system 활용이 남녀노인의 대사증후군 관리에 미치는 영향)

  • Chung, Jin-Wook;Sung, Soon-Chang
    • Journal of Digital Convergence
    • /
    • v.11 no.11
    • /
    • pp.553-560
    • /
    • 2013
  • The purpose of this study was to examine the effect of u-health system on metabolic syndrome risk factor, body composition, and fitness in male and female elderly. Subjects were 46 elderly(24 men and 22 women) with metabolic syndrome. They were divided into u-health group and home exercise group. Blood pressure, blood profile, body composition, and fitness were measured before and after the intervention. As a results, blood glucose and waist circumference showed significant interaction in both men and women, respectively. In body composition, weight, muscle mass, fat mass, %body fat, BMI showed significant interaction whereas only muscle mass showed significant differences in women. In fitness, there were interaction shown in 3m up and go, functional reach, and gait speed in men. In women sit to stand, 6min walk, and grip strength showed significant interaction. In conclusion, u-health system seems to be the effective method in terms of checking regularly. However, easier and more simple system for elderly and specific direction for exercise should be added.