• 한국식품위생안전성학회지
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• 제27권4호
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• pp.339-348
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• 2012

본 연구에서는 향후 고령친화식품의 중심적인 상품군이 될 건강기능식품과 특수용도식품의 시장규모에 대한 예측을 시도하였다. 건강기능식품과 특수용도식품 중 고령친화와 관련된 시장의 범위를 설정하고 현황에 대해서 분석한 후 향후 전망에 대해서 예측하였는데, 경제성장과 민간소비지출의 변화 그리고 이에 따른 노령인구의 경제력 변화, 의료보험 및 연금저축의 변화 등을 반영하였다. 한편 관련기업들을 대상으로 한 설문조사 결과를 활용하는 한편, 노인인구의 변화 및 주요 만성질환의 발병률을 분석하여 예측에 반영하였다. 결과를 보면 2010년부터 2025년까지 건강기능식품과 특수용도식품 중 고령친화와 관련된 부문의 연평균 성장률은 최소 4.54%에서 최대 8.32%로 예측되었으며, 시장규모 예측치는 모형과 예측방식에 따라 2025년에 최소 7,073억원에서 최대 10,976억원으로 나타났다. 향후 고령친화제품의 수요는 고령인구의 증가와 보험급여 확대 등으로 크게 성장할 것으로 예상되는 반면에, 기업들은 수요의 변화를 관망하고 있는 상황으로 판단된다. 따라서 이는 자칫 수요에 비하여 부족한 공급 문제를 야기시킬 수 있다. 따라서 정부의 R&D에 대한 적극적인 지원, 고령친화식품에 대한 표준화 및 인증제 실시, 관련산업의 DB구축 등이 필요한 상황이다.

• 한국응용과학기술학회지
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• 제26권2호
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• pp.143-150
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• 2009

Today, wastes of much quantity by fast industrialization and increase in population, population concentration etc. of modem society are increasing. Much oyster shell is breeding by character and conduct of oyster-industry for a long time among them. Oyster shell which breed by-product in oyster cultivating industry that specific gravity of domestic seashore cultivating industry is high is causing environmental problem by problem and so on hindrance, nature spectacle's waste and health hygiene on administration if it is pollution of district along the coast fishing ground, number of public ownership being stored in open area in seashore. About new material just-in-time through recycling and he of oyster shell by these problem wide that study. Go forward more and investigate special quality that is oyster shell's physical chemistry red in this research and oyster shell oyster shell which cause several environmental problems developing ability agricultural chemicals that use this encapsulating micro by ability carrier that is environmentally application possibility examine wish to.

• Journal of Genetic Medicine
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• 제2권2호
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• pp.83-86
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• 1998

Though Fragile X syndrome is one of the most common inherited causes of mental retardation, it is not much detected yet in Korean population. One of the reason may be that the syndrome is not well known to the special education teachers as well as to the clinicians in this country. Thus, molecular test was undertaken to screen out fragile X syndrome in 122 children of two Korean schools for emotionally severely handicapped children. The subjects were all boys, previously known as having pervasive developmental disorder with or without mental retardation. Southern blot analysis of peripheral blood showed the abnormally enlarged (CGG)n repeat sequence associated with fragile X syndrome in two children. This finding suggests that the DNA testing for fragile X syndrome is warranted for Korean high risk population and that more concern about this syndrome is needed for the professionals who work for mentally handicapped children. The issues involved in genetic counseling for fragile X syndrome are discussed.

• Asian Pacific Journal of Cancer Prevention
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• 제15권20호
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• pp.8549-8556
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• 2014

Head and neck squamous cell carcinoma (HNSCC) is one of the world top ten most common cancers with its highest occurrence in the Indian subcontinent and different aggressive and etiological behavioural patterns. The scenario is only getting worst with the 5 year survival rates dropping to 50%, persistent treatment failures and frequent cases of relapse/recurrence. One of the major reasons for these failures is the presence of cancer stem cells (CSCs), a small population of cancer cells that are highly tumourigenic, capable of self-renewal and have the ability to differentiate into cells that constitute the bulk of tumours. Notably, recent evidence suggests that cancer stem cells are especially resistant to conventional therapy and are the "drivers" of local recurrence and metastatic spread. Specific markers for this population have been investigated in HNSCC in the hope of developing a deeper understanding of their role in oral cancer pathogenesis, elucidating novel biomarkers for early diagnosis and newer therapeutic strategies. This review covers the fundamental relevance of almost all the CSC biomarkers established to date with a special emphasis on their impact in the process of oral tumourigenesis and their potential role in improving the diagnosis, prognosis and treatment of OSCC patients.

• Asian Pacific Journal of Cancer Prevention
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• 제13권3호
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• pp.1077-1079
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• 2012

The Kashmiri population is culturally distinct with special dietary features owing to the temperate climatic conditions of Kashmir valley. This has habituated the population to preserve food in smoked, pickled and sundried forms which include considerable amounts of $N$-nitroso compounds (NOCs). These are known to cause cytotoxicity, DNA damage, mutation, unscheduled DNA synthesis and DNA methylation. All of these changes at molecular level are known to contribute to the pathogenesis of cancer. One of the prominent NOCs found in Kashmiri food is $N$-Nitrosodimethylamine (NDMA). Here we review the occurrence of NDMA in sundried foods, dried fish, kehwa, traditional pickle, $Brassica$ $oleracia$ and $tobbaco$. We also discuss its possible role in the high prevalence of gastrointestinal cancers in Kashmir.

• Advances in aircraft and spacecraft science
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• 제6권5호
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• pp.349-369
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• 2019

In the design of flight control systems there are issues that deserve special consideration and attention such as external perturbations or systems failures. A Simple Adaptive Controller (SAC) that does not require a-priori knowledge of the faults is proposed in this paper with the aim of realizing a fault tolerant flight control system capable of leading the pitch motion of an aircraft. The main condition for obtaining a stable adaptive controller is the passivity of the plant; however, since real systems generally do not satisfy such requirement, a properly defined Parallel Feedforward Compensator (PFC) is used to let the augmented system meet the passivity condition. The design approach used in this paper to synthesize the PFC and to tune the invariant gains of the SAC is the Population Decline Swarm Optimization ($P_DSO$). It is a modification of the Particle Swarm Optimization (PSO) technique that takes into account a decline demographic model to speed up the optimization procedure. Tuning and flight mechanics results are presented to show both the effectiveness of the proposed $P_DSO$ and the fault tolerant capability of the proposed scheme to control the aircraft pitch motion even in presence of elevator failures.

• Journal of Information Technology Applications and Management
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• 제26권2호
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• pp.111-123
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• 2019

In this paper, software activity, software activity instance, and the quality of the activity instance are defined as the 'activity which is performed on the software product by a person or a group of persons,' the 'distinctive and individual performance of software activity,' and the 'performer's evaluation on how good or bad his/her own activity instance is,' respectively. The representative values of the instance quality population associated with a product and its sub-population are defined as the (software) activity quality and activity quality characteristic of the product, respectively. The activity quality model in this paper classifies activity quality characteristics according to the classification hierarchy of software activity by the goal. In the model, a quality characteristic can have two types of sub-characteristics : Special sub-characteristic and component sub-characteristic, where the former is its super-characteristic too simultaneously and the latter is not its super-characteristic but a part of its super-characteristic. The activity quality model is parsimonious, coherent, and easy to understand and use. The activity quality model can serve as a corner stone on which a software quality body of knowledge, which constituted with a set of models parsimonious, coherent, and easy to understand and use and the theories explaining the cause-and-relationships among the models, can be built. The body of knowledge can be called the (grand) activity-centric quality model of software.

• Childhood Kidney Diseases
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• 제23권2호
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• pp.77-85
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• 2019

Contrast-associated acute kidney injury (CA-AKI) is a major concern when iodinated contrast material is administered, especially in patients at risk. Efforts have been undertaken to understand the detrimental effects of contrast media (CM). With the use of low-osmolar or iso-osmolar CM the incidence of CA-AKI has steadily decreased within the past decade; however, especially in the pediatric population information is scarce. Incidence rates have been reported to range between 0% to 18.75%, particularly depending on indication, selection of population (i.e. preexisting co-morbidities), and definition of AKI. Different biomarkers have been proposed, but confirmatory studies are either lacking or have contributed to their lack of diagnostic power. Proteomic approaches have been employed and may pave the way to such discovery. Prevention strategies have been tested and proposed, but the recently published AMACING and PRESERVE trials have shown that commonly used strategies (such as systematic hydration or administration of N-acetylcysteine) have no role in the prevention of CA-AKI. We propose that thoughtful assessment of one's fluid state is the most appropriate approach and depending on the hydration status diuretics or fluid administration should be provided to achieve an euvolemic state ahead of contrast exposure.

• 한국습지학회지
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• 제14권1호
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• pp.89-99
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• 2012

본 연구는 GIS을 활용하여 마산만 특별관리해역 통합관리시스템의 일환으로 마산만의 점 비점오염원 관리시스템을 개발하여 마산만 연안오염총량관리 체제를 보다 체계적이고 과학적으로 이용할 수 있도록 시스템을 구축하였다. 마산만 유역의 오염원 관리에 GIS를 이용한 결과 각 행정구역별 오염원 현황 및 발생 오염부하량의 비교가 가능하였고, 오염부하 산정프로그램을 구축함으로써 배출원별 인구현황, 생활계 물사용량, COD/TN/TP 발생부하량과 배출부하량 등의 오염원 부하량을 행정구역별, 연도별, 용도별로 산정할 수 있었다. 또한 대용량의 속성, 공간자료를 활용함에 있어 시간적, 경제적 노력을 최소화함은 물론 체계적이고 효과적인 마산만 연안오염총량 관리가 가능하여 정책 수립 시 신속한 의사결정에 대한 기여도가 높을 것으로 예상된다. 이 연구결과를 바탕으로 과학적이고 효율적인 점 비점오염원에 관련된 정보와 이에 대한 체계적 관리를 도모하고// 부하량 산정프로그램을 이용하여 오염부하량 변화에 따른 향후 오염원 예측이 가능하도록 유역관리 시스템을 보완해야 할 것이다.

• 한국인구학
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• 제31권3호
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• pp.159-178
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• 2008

이 연구의 목적은 그동안 인구이동 연구 자료의 한계로 인하여 분석되지 못하였던 이동의 선별성과 이동이유를 분석하여 이동의 동인을 밝히는 것이다. 최근 수도권의 인구집중 문제가 다시 부각되고 있기 때문에 분석은 수도권의 인구이동에 초점을 맞추었다. 이 연구에 사용된 자료는 1997년 통계청에서 시행한 인구이동 특별조사의 원자료이다. 분석의 대상은 조사시점 이전 5년간에 시.도간 이동을 경험한 가구주와 단독가구주이다. 선별성 분석은 수도권 이동자를 수도권 전입이동, 전출이동, 그리고 수도권내 이동으로 구분하여 비이동자의 특성과 비교하였다. 이동의 성향은 여성이 남성보다, 20대와 30대 초반 연령층이 다른 연령층에 비해서, 그리고 고학력자가 저학력자보다, 미혼자가 기혼자보다 더 높은 것으로 분석되었다. 수도권을 중심으로 이동의 방향별로 이동이유를 분석한 결과 수도권 전입이동에서는 직업요인이 압도적인 비중을 차지하고 있으며 수도권전출이동에서는 직업요인과 함께 가족요인이 중요하게 작용하고 있었다. 수도권내 이동에서는 직업요인과 함께 가족, 주택요인이 거의 같은 비중으로 이동에 영향을 미치고 있었다. 이동자의 특성과 이동이유를 교차분석해 보면 이동이유에 가장 영향을 많이 미치는 변수는 연령과 혼인상태와 같은 생애주기 변수였으며 이밖에도 학력수준과 거처의 점유형태등의 사회계층과 관련된 변수들도 영향을 미치고 있었다. 교육요인은 수도권 전입이동에 있어서도 그리 큰 비중을 차지하고 있지 않으며 전입과 전출 양방향에서 거의 비슷한 비중을 나타내었다. 결국 수도권 인구집중의 가장 큰 요인은 고학력, 젊은층의 취업관련 이동으로서 이들을 지방에서 정착시킬 수 있는 지방의 취업기회 확대가 수도권 인구집중 완화정책의 요체임을 확인하였다.