• Polymer(Korea)
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• v.32 no.3
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• pp.199-205
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• 2008

In this study, we fabricated poly (lactide-co-glycolide) (PLGA) scaffold modified with small intestinal submucosa (SIS) as a drug delivery matrix of bioactive molecules. SIS derived from the submucosa layer of porcine intestine has been widely used as biomaterial because of low immune response. PLGA scaffold was prepared by the method of solvent casting/salt leaching. Novel composite scaffolds of SIS/PLGA were manufactured by simple immersion method of PLGA scaffold in SIS solution under vacuum. SEM observation shows that PLGA and SIS/PLGA scaffolds have interconnective and open pores. Especially, SIS/PLGA scaffold showed that micro-sponge of SIS with interconnected pore structures were formed in the pores of PLGA scaffold. In order to assay release profile of proteins, we manufactured FITC conjugated BSA loaded PLGA and SIS/PLGA scaffold. And the release amount was identified by fluorescence intensity using the fluorescence spectrophotometer. The initial burst of BSA containing SIS/PLGA scaffolds was lower than that of PLGA scaffolds resulting in constant release. And release of BSA in SIS/PLGA scaffold was fast and incremental because of the increased content of BSA. In conclusion, we confirmed that penetrated SIS solution prevented the initial burst of BSA and PLGA modified with SIS scaffold is useful as protein carriers with controlled release pattern.

• Bulletin of the Korean Mathematical Society
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• v.44 no.4
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• pp.631-640
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• 2007

The purpose of this article is to deal with the multiple values and uniqueness of meromorphic functions with small functions in the whole complex plane. We obtain a more general theorem which improves and extends strongly the results of R. Nevanlinna, Li-Qiao, Yao, Yi, and Thai-Tan.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 1999.12a
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• pp.444-459
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• 1999

• Polymer(Korea)
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• v.32 no.1
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• pp.26-30
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• 2008

This study was designed to investigate the effect of hybridization of synthetic/natural materials for annulus fibrosus (AF) tissue regeneration in vitro and in vivo. The synthetic/natural hybrid scaffolds were prepared using PLGA (poly (lactic-co-glycolic) acid), SIS (small intestinal submucosa) and DBP (demineralized bone particles). PLGA, PLGA/SIS(20%), PLGA/DBP(20%) and PLGA/SIS (10%)/DBP (10%) scaffold were manufactured by solvent casting/salt leaching method. Compressive strength was measured. Rabbit AF cells were isolated, cultured and seeded into experimental groups. Hydroxyproline production and DNA quantity of AP cells on each scaffold was measured at 2, 4 and 6 weeks after in vitro culture. Cell-scaffold composites were implanted subcutaneously into athymic mice. After 1,4 and 6 weeks postoperatively, specimens were taken and H&E, Safranin-O and type I collagen staining were carried out concerning formation of cartilagenous tissue. In vitro PLGA/SIS scaffold was evaluated for total collagen content (bydroryproline/DNA content) and PLGA scaffold was evaluated for compressive strength.

• Asia-Pacific Journal of Atmospheric Sciences
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• v.54 no.4
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• pp.587-598
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• 2018

The impacts of aerosol loading on surface precipitation from mid-latitude deep convective systems are examined using a bin microphysics model. For this, a precipitation case over north central Mongolia, which is a high-altitude inland region, on 21 August 2014 is simulated with aerosol number concentrations of 150, 300, 600, 1200, 2400, and $4800cm^{-3}$. The surface precipitation amount slightly decreases with increasing aerosol number concentration in the range of $150-600cm^{-3}$, while it notably increases in the range of $600-4800cm^{-3}$ (22% increase with eightfold aerosol loading). We attempt to explain why the surface precipitation amount increases with increasing aerosol number concentration in the range of $600-4800cm^{-3}$. A higher aerosol number concentration results in more drops of small sizes. More drops of small sizes grow through condensation while being transported upward and some of them freeze, thus increasing the mass content of ice crystals. The increased ice crystal mass content leads to an increase in the mass content of small-sized snow particles largely through deposition, and the increased mass content of small-sized snow particles leads to an increase in the mass content of large-sized snow particles largely through riming. In addition, more drops of small sizes increase the mass content of supercooled drops, which also leads to an increase in the mass content of large-sized snow particles through riming. The increased mass content of large-sized snow particles resulting from these pathways contributes to a larger surface precipitation amount through melting and collision-coalescence.

• Magazine of the Korean Society of Agricultural Engineers
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• v.35 no.2
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• pp.92-103
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• 1993

A sunday system with a horizontal bin-type composter was constructed and operated to evaluate its composting performance for four days for each test in October, 1992. A sundry system is one of popular systems for composting livestock manure, of which main benefit is to utilize unlimited, clean, and free solar radiation. A rectangular concrete bin(composter) with dimension of 300cm(length) X90cm(width) X60cm(height) was bedded alternatively with four lanes of aeration pipes and heating pipes, and was insulated at three walls with 50mm styrofoam. Each aeration pipe of a diameter of 25mm had 4mm perforated holes at every 15cm longitudinally, and supplied air of about 2m$^3$/min to the composter to maintain aerobic condition . A stirrer rotating at 1 rpm made one round trip every 20 minutes on the conveying chain along the the length of the composter. Five tests (Test 1~Test 5) were implemented to evaluate the composting effectiveness of a sundry system with a horizontal bin-type composter. Treatments of two levels of the mixture ratio of swine manure and paper sludge cakes(manure : paper sludge cakes= 1 : 4 and 1 : 2) and two levels of the water content(W/C ; 70% and 50%) were made to test the significance of the physicochemical properties for decomposition of the mixture materials. Temperature, C/N ratio, water content, microbial activity of the composting materials were taken measurements to evaluate its performance with the lapse of composting time for tests. A small-scale sundry system with a bin-type composter did not appear to be an appropriate system for composting livestock manure. Since heat generation by the composting materials could not overcome heat loss due to areation in a small-scale composter, a proper thermal enviroment could not be maintained to propagate massively thermopilic microorganism relatively in a short period of time. Different from the result of Chol et al.(1992) 6), a temperature variation of the composting materials did not show the peak clearly and C/N ratio didn't lower with time as expected. Mesophilic microoragnism seemed to play an important role for decomposition of the mixture materials. A sundry system with a bin-type composter may be good for a large-scale livestock farm household which may produce enough animal manure. Therefore a decision should be made very carefully to choose a system for composting livestock waste.

• Proceedings of the KIEE Conference
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• 2001.07d
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• pp.2390-2392
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• 2001

The small gear head noise is caused by gear accuracy, assembling errors, and gear backlash. This main study is an investigation on noise quality of the small gear head through the change of gear backlash. In this study included gear design parameters related the small gear head, the knowledge of rattle noise related gear backlash, and the experimentation results of the small head noise through change of gear backlash. At last, this study propose the least method of the small gear head noise that is caused by suitable existence of gear backlash.

• Journal of the Korean Society of Safety
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• v.28 no.2
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• pp.84-87
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• 2013

National industrial accidents, most recently occurred in the small to medium-sized industries. These companies' management for the prevention of industrial accidents, the role of the supervisor has emerged as an important issue. Small to medium-sized industries to enhance their effectiveness in the prevention of industrial accidents supervisors of work status survey and direct interviews were conducted. Proposal paper was based on the results of analysis for the role of supervisors by providing safety and health work systematically to participate.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.36 no.4
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• pp.9-17
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• 2013

The purpose of this study is to figure out the impacts of technological innovation and cost management on productivity in small shipping industries to come up with developmental implications. To achieve this, a survey was carried out to 150 workers in small shipbuilding industries through April 2 to April 20, 2012. As for findings stated above, technological innovation and cost management in the Korean small shipbuilding industries were key factors that elevate financial and non-financial productivity. In the light of low technological prowess and cost structure of small shipbuilding industries, their productivity can be improved when intensive cost management with production factor technology as know-how is realized through quality management, which product development technology is the top priority as an independent niche strategy. Consequently, the combination of infrastructures in small shipbuilding industries with continuous efforts for cost reduction by the link to the systematized structure can't only secure their independent competitiveness, but raise their productivity.

• Korean Journal of Environmental Agriculture
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• v.20 no.3
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• pp.135-142
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• 2001

Compostable household wastes(mainly food wastes), after waste papers and cardboard being removed, were daily fed into small bins and mixed thoroughly while the air was supplied into the bin. Three small bins were employed: in case I, only recycled compost was composted, after being once fed at the beginning of composting, in case II, compostable household wastes(less than 50 mm) torn roughly by the hands with recycled compost, and in case III, compostable household wastes(less than 2 mm) ground by a kitchen mixer for vegetables with recycled compost. The straight-line was maintained between the wet or the dry residual mass of composting mixture versus composting time date(the coefficient of determination $R^2{\geq}0.98$ for the wet and $R^2{\geq}0.90$ for the dry). The decomposition rate of each composted material was estimated during composting. The total weight reduction rate after 30 days was 67.86% and 66.14% for case II and III, respectively. For case II, the daily weight reduction 6.82% and the daily decomposition rate 8.81% with the composting mixture, but the daily weight reduction rate was 56.43% and the daily decomposition rate 19.26% with only compostable household wastes. For case III, the daily reduction rate was 6.93% and the daily decomposition rate 7.70% with the composting mixture, but the daily weight reduction rate was 53.30% and the daily decomposition rate 22.95% with only compostable household wastes. The physicochemical characteristics of composting mixture did not show much difference between case II and III as was expected.