• 제목/요약/키워드: skin health

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Effects of Human Adipose-Derived Stem Cells on the Survival of Rabbit Ear Composite Grafts

  • Kim, Chae Min;Oh, Joo Hyun;Jeon, Yeo Reum;Kang, Eun Hye;Lew, Dae Hyun
    • Archives of Plastic Surgery
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    • v.44 no.5
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    • pp.370-377
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    • 2017
  • Background Composite grafts are frequently used for facial reconstruction. However, the unpredictability of the results and difficulties with large defects are disadvantages. Adipose-derived stem cells (ADSCs) express several cytokines, and increase the survival of random flaps and fat grafts owing to their angiogenic potential. Methods This study investigated composite graft survival after ADSC injection. Circular chondrocutaneous composite tissues, 2 cm in diameter, from 15 New Zealand white rabbits were used. Thirty ears were randomly divided into 3 groups. In the experimental groups (1 and 2), ADSCs were subcutaneously injected 7 days and immediately before the operation, respectively. Similarly, phosphate-buffered saline was injected in the control group just before surgery in the same manner as in group 2. In all groups, chondrocutaneous composite tissue was elevated, rotated 90 degrees, and repaired in its original position. Skin flow was assessed using laser Doppler 1, 3, 6, 9, and 12 days after surgery. At 1 and 12 days after surgery, the viable area was assessed using digital photography; the rabbits were euthanized, and immunohistochemical staining for CD31 was performed to assess neovascularization. Results The survival of composite grafts increased significantly with the injection of ADSCs (P<0.05). ADSC injection significantly improved neovascularization based on anti-CD31 immunohistochemical analysis and vascular endothelial growth factor expression (P<0.05) in both group 1 and group 2 compared to the control group. No statistically significant differences in graft survival, anti-CD31 neovascularization, or microcirculation were found between groups 1 and 2. Conclusions Treatment with ADSCs improved the composite graft survival, as confirmed by the survival area and histological evaluation. The differences according to the injection timing were not significant.

Contents Analysis on Medical Reports of High-Rise Condominium Residents (주상복합아파트 거주자의 질병자료 내용 분석)

  • Kang, In-Ho;Choi, Byung-Sook
    • Journal of the Korean housing association
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    • v.19 no.5
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    • pp.57-65
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    • 2008
  • The purpose of this study is to figure out the relationship between the residence stories in high-rise condominium and residents' disease patterns throughout the dweller's medical reports. Research basic data are obtained from medical fee request of National Health Insurance Corporation. Data are limited to 'A' high-rise condominium and a medical treatment time to 3 years (2004. 1-2006, 12). Data for analysis are composed of total 346,286 medical records, 43,159 disease records, and 8,999 personal records. Data are stored by sex, age, building story, residence story, visiting year and month, treatment days, main disease type (KCD-4). Treatment number, disease type and asthma in disease records and personal records are statistically analyzed by residence story considering age. Findings are as follows: 1) Women have more medical treatments than men, 40-50 age group is more treated, and the residents of 6-25 stories are more received medical treatments. According to KCD-4, diseases of the respiratory system and diseases of the eye and adnexa are relatively treated higher than other diseases. 2) The diseases of he respiratory system, the eye and adnexa, the skin and subcutaneous issue, the ear and mastoid process, and the asthma have not relation to the high-storied residence through the data of disease records and personal records. But the analysis on the data of children, age 7 and less, showed a significant relation. to conclude, there is no relationship between the residence of high-stories in the condominium and residents' disease patterns, but there is a little probable to the relationship in the pre-school child.

Cytomorphologic Patterns of Breast Lesions in Sudanese Patients: Lessons Learned from Fine Needle Aspiration Cytology

  • Almobarak, Ahmed Omer;Elhassan, Taiseer Mohamed;Elhoweris, Mohamed Hassan;Awadalla, Heitham Mohammed;Elmadhoun, Wadie Mohamed Yasin;Ahmed, Mohamed Hassan
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3411-3413
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    • 2014
  • Background: Cytology for breast lesions is a safe, rapid and cost-effective with a high specificity and sensitivity. Objective: To determine the cytomorphologic patterns of breast lesions identified among a group of Sudanese patients. Materials and Methods: This study included 759 patients undergoing either a fine needle aspiration FNA, nipple discharge (ND) smears or breast skin scraping (SS) at a cytology clinic in Khartoum. Clinical and demographic data were reviewed. Stained smears were categorized into: inadequate sample, normal breast, benign lesion, suspicious, or malignant neoplasm. Results: Of the 759 cases, 734 (96.71%) were FNA, 18 (2.37%) ND and 7 cases (0.92%) SS. For 28 cases, FNA was done under ultrasound guidance. Females were 720 (94.86%). Benign lesions were 423 (55.75%) and 248 (32.67%) were malignant and 77 (10.14%) of smears were normal without any detected abnormality. Ten (1.31%) cases were suspicious for malignancy, and only one case (0.13%) was reported as inadequate. Most lesions were observed among the age group 30 years and above. Conclusions: Most patients investigated have benign lesions, one third of cytological smears were malignant. FNAC is a useful tool for investigating breast lesions in limited-resource settings.

Suitability of Setting Summer Indoor Temperature for Thermal Comfort (여름철 실내 쾌적온도 설정 기준의 적합성)

  • Shim, Huen Sup;Jeong, Woon Seon
    • The Korean Journal of Community Living Science
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    • v.24 no.4
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    • pp.583-589
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    • 2013
  • This study was to provide the information for optimum utilization of the air-conditioning system in the human health and energy saving perspective. Subjects were 17 male and female college students(7 males and 10 females) with normal weight. They wore a short sleeved shirt, knee length trousers, socks, and underwear(0.4clo). They were asked to choose the preferred temperature from different environmental temperatures($28^{\circ}C$, $25^{\circ}C$). The physiological responses were measured and the subjective sensation was voted during the step changes of environmental temperature, starting at $28^{\circ}C$ to $25^{\circ}C$ with $1^{\circ}C$ decrease every 20 minutes. The preferred temperature was $25.9{\pm}0.4^{\circ}C$ for males and $26.9{\pm}0.2^{\circ}C$ for females at $28^{\circ}C$ and $24.8{\pm}0.6^{\circ}C$ for males and $25.6{\pm}0.1^{\circ}C$ for females at $25^{\circ}C$. The preferred temperature decreased about $1.3^{\circ}C$ while the environmental temperature changed $3^{\circ}C$. During the environmental step changes, mean skin temperature decreased more in females while the oxygen uptake and rectal temperature were kept constant for both males and females. We found the preferred temperature was affected by the exposed temperature and the thermal sensation in the condition. Subjects preferred a lower environmental temperature when they were exposed to a lower temperature with cooler sensation. Therefore, in the perspective of human health and energy saving, it is recommended to start setting the air-conditioning temperature higher than the preferred temperature.

A Study for Farmers to Reduce Work Load on the Different Working Conditions (part II) - Cultivating Welsh Onion in the Summer Ground - (농민의 작업환경별 노동부담경감방안에 관한 연구(II) - 여름철 노지에서 대파재배 작업을 중심으로 -)

  • 김명주;최정화
    • Korean Journal of Rural Living Science
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    • v.8 no.2
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    • pp.119-124
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    • 1997
  • In this study we tried to give a decision on propriety of working conditions, to present ideas on reducing work loads, and to grope for efficiency of agricultural works. For this we examined the actual working conditions of cultivating welsh onion in the summer ground. And we improved harmful factors that affect farmer's health by considering results of previous study and farmer's subjective sensation. And we measured. compared, and analyzed the farmer's work loads before and after improvement. The results of this study are as follows ; 1. According to examine the actual working conditions of cultivating welsh onion in the summer ground, farmers have experienced physical and mental chronic fatigue on the basis of farmer's appel to eye - fatigue and sun - burned skin on hot working environment including excessive ultraviolet rays, the rough ground condition, inconsistent arrangement of working stand and sorter, heavy - weared habits, and unsuitable working posture. 2. When we improved harmful factors that affect farmer's health, conformed the effects on important work efficiency index such as heart rate, electromyovolume, body temperature, and microclimate inside clothing and work loads were decreased by eliminating the hillock and obstacles of ground, decreasing the clothing weight, using proper clothing appliances such as hat and sunglasses, controlling height of working stand and sorter suitably, improving the working postures and methods as using assistant appliances, alloting the working time and sequence effectively and presenting the light gymnastic exercises and rest for fatigue restoration.

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A Study on the Cleaning Efficiency using the d-Limonene Oil Extracted in Wasted Mandarin Peels (폐감률피에서 추출한 limonene 오일의 세정성에 관한 연구)

  • Song, Min-Kyung;Oh, Eun-Ha;Im, Ho-Sub;Kim, Yoon-Shin
    • Journal of the Korean Applied Science and Technology
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    • v.27 no.2
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    • pp.107-113
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    • 2010
  • The object of this research is to conform of practicable possibility and recycling of producing junk after citrus fruits is processed. With extracting d-limonene oil that have 70~90% a component of oil out of junk citrus peel, making certain the about 12000ppm concentration of it. Limonene derived from citrus in jeju using conventional synthetic detergents can be replaced with the development of environmentally friendly natural detergent investigated the possibility. Mostly due to ocean dumping, disposal and cause environmental problems by recycling natural citrus cleaner alternative to the research conducted on the possibility. Cleaning efficiency with temperature did not affect the largest concentrations were able to identify the difference between cleaning efficiency. At least 10% of the d-limonene oil could be from the cleaning performance, increasing the concentration of the cleaning efficiency was increased in size. Ultrasonic is very high removal efficiency under the conditions shown in the cause of pure self-generated ultrasonic cleaning power as co-effects of d-limonene oil appears to chemical cleaning effect of ultrasonic cavitation occurs in the physical cleaning effect due to a combination of synergistic stability is maximized by low concentrations of d-limonene oil in a short time showed an excellent cleaning ability. Having the ability of cleaning at the same time, considering the side recycling in the junk citrus peels reflects possibility of basic materials utility eco-friendly in the skin soap, bath soap, cosmetics etc, through ability of exclusion a contaminant in based cleaning effect(EC) it can prospect substitution effect environmentally in the pre existence synthetic detergents.

The Effect of Lactobacillus Mixture Culture Fluid Extracts on Atopic Dermatitis Chemokine Expression of in HaCaT Cells (HaCaT 세포에서 Lactobacillus 혼합배양액 추출물이 아토피관련 케모카인 발현에 미치는 효과)

  • Hong, Soo-Jeong;Lee, Won-Jae;Jo, Eul-Hwa;Ahn, Seong-Hun
    • Korean Journal of Acupuncture
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    • v.34 no.2
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    • pp.82-87
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    • 2017
  • Objectives : Recently the case of lactobacillus mixture culture fluid appliment was reported. In this study, anti-inflamation effects and anti-allergy effects were studied by stimulus of lactobacillus mixture culture fluid extracts in HaCaT cells. Methods : The atopic dermatitis were induced by TNF-${\alpha}$ and interferon-${\gamma}$ in HaCaT cells. TARC/CCL17, MDC/CCL22, RANTES/CCL5 and ROS production were investigated to explain anti-inflamation and allergy effects of lactobacillus mixture culture fluid with cell-enzyme-linked Immunosorbent assay in 450 nm, 485 nm, 535 nm with spectro-fluorometer. Results : The extracts of lactobacillus mixture culture fluid were decreased TARC/CCL17, MDC/CCL22, RANTES/CCL5 expressions and ROS production with a concentration dependent manner. Conclusions : The effects mechanism of Lactobacillus mixed culture fluid for atopic dermatitis symptoms were considered to be explain anti-inflamation and allergy effects via control of cytokine, chemokine and ROS production, and the fluid could be applied in skin cells directly. But classified AD symptom degrees reported in clinical case before as Reaction Period, Reduction Period, Effect Period, Reproduction Period and Rebound Period could not be explained. Further study will be expected.

Development of Algorithms for the Home Care of Cancer Chemotherapy Patients (재가 항암화학요법을 받는 암환자의 가정간호중재 알고리즘 개발)

  • Park, Jung-Ho;Kim, Mae-Ja;Hong, Kyung-Ja;Han, Kyung-Ja;Park, Sung-Ae;Yun, Soon-Nyoung;Lee, In-Sook;Cho, Hyun;Shin, Gye-Young;Bang, Kyung-Sook
    • Journal of Home Health Care Nursing
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    • v.5
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    • pp.32-46
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    • 1998
  • Cancer is a leading cause of death, and the number of cancer patients is increasing in Korea. The needs for the home care of cancer patients are increasing recently, but the standardized home care protocols are not developed yet. This study was designed to develop nursing assessment -intervention algorithms for the cancer chemotherapy patients at home. These algorithms suggest guidelines when we assess the patient's condition, and find appropriate nursing interventions, so that standardization and quality control of home care can be attained. The algorithms were processed by yes-no tree. Eleven common problems of cancer chemotherapy patients were identified by the literature review and oncology nurses' experience. These were digestive dysfunction, pain, fatigue, infection, respiratory difficulties, activity intolerance, hemorrhage, sensory disorder, edema, skin problem, and mucosal problem. The algorithm needs to be validated and modified by using for the cancer chemotherapy patients at home.

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The Immediate Effects of Functional Taping on Pain, Muscle Strength, and Range of Motion of the Shoulder After Surgery in Patients With Rotator Cuff Tears (기능적 테이핑이 어깨둘레근 수술 후 환자의 어깨관절 통증과 근력, 관절가동범위에 미치는 즉각적 영향)

  • Mun, Yu-ri;Kim, Suhn-yeop
    • Physical Therapy Korea
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    • v.24 no.1
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    • pp.19-29
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    • 2017
  • Background: Patients after rotator cuff (RC) surgery experienced pain, weakness and limited of motion of the shoulder. Physical therapists have used heat therapy, electrotherapy, range of motion (ROM) exercise and other methods to treat patients after RC surgery. In addition, functional taping is also used to support joint movement and to increase shoulder joint stability. Objects: The purpose of this study was to determine the initial effects of functional taping using non-elastic tape on pain, strength and ROM of the shoulder following RC surgery. Methods: Forty-eight patients with who underwent RC surgery volunteered for this study. The subjects were randomly divided into an experimental group (EG, $n_1=25$) and a control group (CG, $n_2=23$). First, non-allergic tape was applied to the shoulder to prevent skin irritation. The EG applied functional taping using non-elastic tape and the CG applied sham taping using elastic tape. Assessment tools included the shoulder pain and disability index for functional activity score, visual analog scale for level of pain, shoulder muscle strength, hand grip strength and ROM testing. Results: Pain score in the both group significantly decreased (p<.05), and change in pain score of in the EG increased significantly than in the CG (p<.05). Shoulder strength and ROM in the both group significantly increased (p<.05). Especially external rotation and extension of the shoulder ROM in the EG increased significantly more than in the CG (p<.05), but the rate of change in the two groups showed no significant difference. Conclusion: These results suggest that functional taping using non-elastic tape was initially effective in decreasing pain score level in patients with RC surgery.

Inhibitory Effects of Gosambaeksunpibokhap-bang(GBBB) Extract in an Atopic Dermatitis Animal Model (아토피 동물모델에서 고삼백선피복합방(GBBB)의 아토피 억제효과)

  • Lee, Da-Yeong;Seung, Yun-Chel;Cheong, Kyu-Jin
    • Journal of Digital Convergence
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    • v.14 no.11
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    • pp.607-618
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    • 2016
  • In order to clarify the Gosambaeksunpibokhap-bang(GBBB)'s therapeutic possibility on atopic dermatitis (AD), influences of GBBB on the changes of various immune-related factors and histological changes in NC/Nga mice were evaluated. Experimental results are as follows. Sign of recovery from AD was observed in GBBB treated group with naked eye test. The ratio of white blood cells, neutrophil, lymphocytes, monocyte in blood were decreased to 54%, 63%, 57% and 86% respectively in the GBBB group. IL-4, IL-5, IL-13, Histamine and IgE were significantly decreased to 40%, 80%, 62%, 61% and 57% respectively in the GBBB group. H&E staining showed thickness of epidermis and dermis were decreased by GBBB and inhibited the infiltration of lymphocytes. On the basis of these results, GBBB was confirmed that the possibility as an AD treatment applied externally to the skin. In the further study, immune control mechanism of GBBB will be demonstrated through the additional molecular biological research.