• Journal of Sensor Science and Technology
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• v.32 no.1
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• pp.39-43
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• 2023

Microscale thermophysical property measurements of liquids have been developed considering the increasing interest in the thermal management of cooling systems and energy storage/transportation systems. To accurately predict the heat transfer performance, information on the thermal conductivity, heat capacity, and density is required. However, a simultaneous analysis of the thermophysical properties of small-volume liquids has rarely been considered. Recently, we proposed a new methodology to simultaneously analyze the aforementioned three intrinsic properties using heater-integrated fluidic resonators (HFRs) in an atmospheric pressure environment comprising a microchannel, resistive heater/thermometer, and mechanical resonator. Typically, the thermal conductivity and volumetric heat capacity are measured based on a temperature response resulting from heating using a resistive thermometer, and the specific heat capacity can be obtained from the volumetric heat capacity by using a resonance densitometer. In this study, we analyze methods to improve the thermophysical property measurement performance using HFRs, focusing on the effect of the ambience around the sensor. The analytical method is validated using a numerical analysis, whose results agree well with preliminary experimental results. In a vacuum environment, the thermal conductivity measurement performance is enhanced, except for the thermal conductivity range of most gases, and the sensitivity of the specific heat capacity measurement is enhanced owing to an increase in the time constant.

• Analytical Science and Technology
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• v.23 no.3
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• pp.255-260
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• 2010

The Ministry of Environment simultaneously revised testing methods and emission standards of adhesives product on the "Law of indoor air quality management" for the effective management of the building materials releasing pollutants in great quantities. Accordingly, it is impossible to compare original standards with revised standards directly. The influences of each factor of the revised testing methods of adhesive product on the emission rate of pollutants are reviewed through comparing with the original testing method. Through this study, revised pollutant emission control standards were assessed. With the result that it is found that emission rate of adhesives product is weakened two and half times by changing test period and the emission rate resulting from changing drying time has little difference. As a result of comparing TVOC emission standards with the original testing method considering the modification of testing methods, it is found that the emission standard through this revision is strengthened about 2.1 times more than that of present testing method.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.29 no.11 s.242
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• pp.1527-1533
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• 2005

Three methods for design sensitivity analysis such as finite difference method(FDM), direct differentiation method(DDM) and adjoint variable method(AVM) are well known. FDM and DDM for design sensitivity analysis cost too much when the number of design variables is too large. An AVM is required to compute adjoint variables from the simultaneous linear system equation, the so-called adjoint equation. Because the adjoint equation is independent of the number of design variables, an AVM is efficient for when number of design variables is too large. In this study, AVM has been extended to the eigenproblem of damped systems whose eigenvlaues and eigenvectors are complex numbers. Moreover, this method is implemented into a commercial finite element analysis program by means of the semi-analytical method to show applicability of the developed method into practical structural problems. The proposed_method is compared with FDM and verified its accuracy for analytical and practical cases.

• Natural Product Sciences
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• v.18 no.3
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• pp.171-176
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• 2012

We previously isolated cordycepin, guanosine and tryptophan from Cordyceps militaris as antiadipogenic constituents. For the quality control of C. militaris for anti-adipogenic activity, simultaneous analytical method using high-performance liquid chromatography (HPLC)-diode array detection (DAD) was developed and validated. Quantitation of these compounds in various Cordyceps samples from different sources and various extraction methods were conducted using developed method. Our study shows that natural Cordyceps and host insect possess higher content than cultured ones and fruiting bodies, respectively. The content of cordycepin showed great difference in different C. militaris samples whereas trytophan content was similar in tested samples. Addition of water to extraction solvent greatly increased the yield of guanosine and tryptophan. High temperature and longer extraction time increased yield of guanosine, whereas the content of trytophan was decreased in high temperature during extraction with water. Extraction using ultrasonic apparatus slightly increased extraction efficiency. Cordycepin, however, has little variation in different extraction method tested. Strong anti-adipogenic activity was observed in the samples that contain all the three constituents. Taken together, quantitation of these compounds using developed analytical method might provide basic requirement for the anti-adipogenic activity of C. militaris.

• Advances in nano research
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• v.16 no.1
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• pp.27-40
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• 2024

This work is the first of its kind to integrate Mindlin's theory with analytical methods in order to produce an exact solution to a specific vibration issue as well as a bending problem involving a nanoplate that is supported by a viscoelastic foundation. The plate is exposed to the simultaneous effects of a compressive load in the plate plane and a force operating perpendicular to the plane of the nanoplate. In addition, the flexoelecity effect is included into the plate. The strain gradient component is taken into consideration while calculating the plate equilibrium equation using the nonlocal theory and Hamilton's principle. The free vibration and static responses of the nanoplate seem to be both real and imaginary components because of the appearance of the viscoelastic drag coefficient of the viscoelastic foundation. This study also shows that when analyzing the mechanical response for nanostructure, taking into account the flexoelectricity effect and the influence of the nonlocal parameter, the results will be completely different from the case in which this parameter is ignored. This indicates that it is vital to take into consideration the effects of nonlocal parameters on the nanosheet structure while also taking into consideration the effect of flexoelectricity.

• Mass Spectrometry Letters
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• v.3 no.3
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• pp.68-73
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• 2012

Fat malabsorption is an important cause of poor growth in infancy and childhood. Steatorrhea tests have been developed using various methods. Traditional measurements of stool fat, however, require large samples and it often takes as a week to complete the analysis. In this paper, a liquid chromatography-electrospray ionization/mass spectrometry (LC-ESI/MS) method was developed for simultaneous quantitative analysis of triacylglycerols, triolein, diolein and monoolein, in mouse feces. Moreover, the procedure was rapid, simple as well as compatible with LC-ESI/MS. Chloroform-isopropyl alcohol solution was used for fat-soluble sample extraction. After centrifugation and filtration, an analytical solution was prepared. Triolein, diolein and monoolein were separated using non-aqueous reversed-phase column with the mobile phase consisting of A (methanol) and B (acetone-isopropyl alcohol). The precision (% CV) and accuracy (% bias) of the assay were 3.8-14.7% and 85.2-114.9%, respectively. This method has been successfully applied to simultaneous determination of triolein, diolein and monoolein in feces from 30 mice. This method can therefore be applied to measure triacylglycerols in mouse feces accurately and precisely by LC-ESI/MS, thereby helping to predictive biomarker in fat malabsorption and diagnostic research.

• Herbal Formula Science
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• v.20 no.2
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• pp.37-46
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• 2012

Objectives : Oyaksungi-san(Wuyaoshunqisan) has been used for treatment of stroke and rheumatoid arthritis in Korea. In this study, a simple and accurate high-performance liquid chromatography(HPLC) method was established for simultaneous determination of six main components, liquiritin, ferulic acid, naringin, hesperidin, neohesperidin, and glycyrrhizin in Oyaksungi-san, a traditional Korean herbal prescription. Methods : The analytical column for separation of six constituents was used a Gemini $C_{18}$ column maintained at $40^{\circ}C$. The mobile phase consisted of two solvent systems, 1.0% (v/v) acetic acid in $H_2O$ (A) and 1.0% (v/v) acetic acid in acetonitrile (B) by gradient flow. The flow rate was 1.0 mL/min and the detector was a photodiode array (PDA) set at 254 nm for glycyrrhizin, 280 nm for liquiritin, naringin, hesperidin, and neohesperidin, and 320 nm for ferulic acid. Results : Calibration curves were acquired with $r^2$ values ${\geq}0.9998$. The results of recovery test were 91.58%-105.90% with a relative standard deviations (RSDs, %) value less than 2.0%. The values of RSD for intra- and inter-day precision were 0.03%-1.72% and 0.03%-1.63%, respectively. The contents of the six compounds in Oyaksungi-san were 0.33-9.30 mg/g. Conclusions : The newly established HPLC method will be helpful to improve quality control of Oyaksungi-san.

• Proceedings of the Korea Electromagnetic Engineering Society Conference
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• 2002.11a
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• pp.324-327
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• 2002

For the characterization of arbitrary shaped printed circuit board, lossy transmission line grid model based on SPICE netlist and analytical plane model based on the segmentation method are proposed in this paper. Two methods are compared with an arbitrary shaped power/ground plane. Furthermore, design considerations for the complete power distribution network structure are discussed to ensure the maximum value of the PDN impedance is low enough across the desired frequency range and to guide decoupling capacitor selection.

• Journal of the Korea Concrete Institute
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• v.12 no.5
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• pp.101-110
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• 2000

A practical approach of calculating the ultimate strength of composite beams with unreinforced web opning is proposed through shear behavioral tests. In this method, the slab shear contribution at the opening is calculated as the smaller value of the pullout capacity of shear connector at the high moment end and the one way shear capacity of slab. A simple interaction equation is used to predict the ultimate strength under simultaneous bending moment and shear force. Strength prediction by the proposed method is compared with previous test results and the predictions by other analytical methods. The comparison shows that the proposed method predicts the ultimate capacity with resonable accuracy.

• Journal of Applied Biological Chemistry
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• v.64 no.1
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• pp.57-61
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• 2021

Saikosaponin derivatives such as saikosaponins A, B1, B2, B3, B4, C, and D present in Bupleurum falcatum were analyzed by a high performance liquid chromatograph equipped with an evaporative light scattering detector, using different extraction solvents (water and 70% ethanol). The samples were injected into a YMC Pack Pro C18 column and separated using a gradient elution system with a mobile phase composed of acetonitrile and water at a flow rate of 1.1 mL/min. The content of saikosaponin derivatives was higher in 70% ethanol extract than in water extract. This study provides an efficient analytical method for determining the optimal conditions for extraction of saikosaponin derivatives, which can be used as a basis for development of functional foods and pharmaceutical products from B. falcatum.