• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.2
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• pp.370-376
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• 2022

Smart ships related studies are being conducted in various fields owing to the development of technology, and an engine room patrol robot that can patrol the unmanned engine room is one such study. A patrol robot moves around the engine room based on the information learned through artificial intelligence and checks the machine normality and occurrence of abnormalities such as water leakage, oil leakage, and fire. Study on engine room patrol robots is mainly conducted on machine detection using artificial intelligence, however study on movement and control is insufficient. This causes a problem in that even if a patrol robot detects an object, there is no way to move to the detected object. To secure maneuverability to quickly identify the presence of abnormality in the engine room, this study experimented with whether a patrol robot can determine the shortest path by applying the A* algorithm. Data were obtained by driving a small car equipped with LiDAR in the ship engine room and creating a map by mapping the obtained data with SLAM(Simultaneous Localization And Mapping). The starting point and arrival point of the patrol robot were set on the map, and the A* algorithm was applied to determine whether the shortest path from the starting point to the arrival point was found. Simulation confirmed that the shortest route was well searched while avoiding obstacles from the starting point to the arrival point on the map. Applying this to the engine room patrol robot is believed to help improve ship safety.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.39 no.6
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• pp.541-548
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• 2021

Recently, multispectral cameras are being actively utilized in various application fields such as agriculture, forest management, coastal environment monitoring, and so on, particularly onboard UAV's. Resultant multispectral images are typically georeferenced primarily based on the onboard GPS (Global Positioning System) and IMU (Inertial Measurement Unit)or accurate positional information of the pixels, or could be integrated with ground control points that are directly measured on the ground. However, due to the high cost of establishing GCP's prior to the georeferencing or for inaccessible areas, it is often required to derive the positions without such reference information. This study aims to provide a means to improve the georeferencing performance of a multispectral camera images without involving such ground reference points, but instead with the simultaneously onboard high resolution RGB camera. The exterior orientation parameters of the drone camera are first estimated through the bundle adjustment, and compared with the reference values derived with the GCP's. The results showed that the incorporation of the images from a high resolution RGB camera greatly improved both the exterior orientation estimation and the georeferencing of the multispectral camera. Additionally, an evaluation performed on the direction estimation from a ground point to the sensor showed that inclusion of RGB images can reduce the angle errors more by one order.

• Biomolecules & Therapeutics
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• v.30 no.3
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• pp.246-256
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• 2022

The present study focused on the potential mechanism of betulin (BT), a pentacyclic triterpenoid isolated from the bark of white birch (Betula pubescens), against chronic alcohol-induced lipid accumulation and metaflammation. AML-12 and RAW 264.7 cells were administered ethanol (EtOH), lipopolysaccharide (LPS) or BT. Male C57BL/6 mice were fed Lieber-DeCarli liquid diets containing 5% EtOH for 4 weeks, followed by single EtOH gavage on the last day and simultaneous treatment with BT (20 or 50 mg/kg) by oral gavage once per day. In vitro, MTT showed that 0-25 mM EtOH and 0-25 µM BT had no toxic effect on AML-12 cells. BT could regulate sterolregulatory-element-binding protein 1 (SREBP1), lipin1/2, P2X7 receptor (P2X7r) and NOD-like receptor family, pyrin domains-containing protein 3 (NLRP3) expressions again EtOH-stimulation. Oil Red O staining also indicated that BT significantly reduced lipid accumulation in EtOH-stimulated AML-12 cells. Lipin1/2 deficiency indicated that BT might mediate lipin1/2 to regulate SREBP1 and P2X7r expression and further alleviate lipid accumulation and inflammation. In vivo, BT significantly alleviated histopathological changes, reduced serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) and triglyceride (TG) levels, and regulated lipin1/2, SREBP1, peroxisome proliferator activated receptor α/γ (PPARα/γ) and PGC-1α expression compared with the EtOH group. BT reduced the secretion of inflammatory factors and blocked the P2X7r-NLRP3 signaling pathway. Collectively, BT attenuated lipid accumulation and metaflammation by regulating the lipin1/2-mediated P2X7r signaling pathway.

• Food Science and Industry
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• v.55 no.1
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• pp.58-73
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• 2022

Due to the recent demand for low-calorie foods, consumers are looking for alternative sweeteners that can control blood sugar, low risk of tooth decay and low calories. Regulations for permitted sweeteners in food vary from every country, and it is important for the government and the food industry to monitor products containing these sweeteners to ensure global compliance. Therefore, rapid, precise, and accurate analysis for food matrices should be applied to quality control, market surveillance, monitoring, and evaluation of food additive intake in the food industry. To analyze sweeteners simultaneously, it is essential to develop an efficient and rapid analytical method and to perform appropriate pretreatment steps such as solvent extraction and purification. This study presented the recent analysis trends about the suitable extraction method for food matrices focusing on non-nutritive sweeteners. Additionally, techniques for multi-compounds analysis using HPLC and LC-MS/MS and non-destructive analysis techniques using FT-IR were comprehensively described.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.35 no.3
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• pp.141-148
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• 2022

In this study, the structural behavior of reinforced concrete members under simultaneous axial and blast loads was analyzed. Nonlinear dynamic analysis verification was performed using the experimental data of panels under fundamental blast load as well as those of reinforced concrete columns subjected to axial and blast loads. Because Autodyn is a program designed only for dynamic analysis, an analysis process is devised to simulate the initial stress state of members under static loads, such as axial loads. A total of 80 nonlinear dynamic finite element analysis procedures were conducted by selecting parameters corresponding to axial load ratios and scaled distances ranging 0%~70% and 1.1~2.0 (depending on the equivalent of TNT), respectively. The structural behavior was compared and analyzed with the corresponding degree of damage and maximum lateral displacement through the changes in axial load ratio and scaled distance. The results show that the maximum lateral displacement decreases due to the increase in column stiffness under axial loads. In view of the foregoing, the formulated analysis process is anticipated to be used in developing blast-resistant design models where structural behavior can be classified into three areas considering axial load ratios of 10%~30%, 30%~50%, and more than 50%.

• Tunnel and Underground Space
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• v.31 no.6
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• pp.480-493
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• 2021

Since the generalized Hoek-Brown criterion (GHB) provides an efficient way of identifying its strength parameter values with the consideration of in-situ rock mass condition via Geological Strength Index (GSI), this criterion is recognized as one of the standard rock mass failure criteria in rock mechanics community. However, the nonlinear form of the GHB criterion makes its mathematical treatment inconvenient and limits the scope of its application. As an effort to overcome this disadvantage of the GHB criterion, the explicit approximate analytical equations for the minimum principal stress, which is associated with the maximum principal stress at failure, are formulated based on the Taylor polynomial approximation of the original GHB criterion. The accuracy of the derived approximate formula for the minimum principal stress is verified by comparing the resulting approximate minimum principal stress with the numerically calculated exact values. To provide an application example of the approximate formulation, the equivalent friction angle and cohesion for the expected plastic zone around a circular tunnel in a GHB rock mass are calculated by incorporating the formula for the approximate minimum principal stress. It is found that the simultaneous consideration of the values of mi, GSI and far-field stress is important for the accurate calculation of equivalent Mohr-Coulomb parameter values of the plastic zone.

• Journal of Navigation and Port Research
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• v.46 no.3
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• pp.203-208
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• 2022

Recently, various digital technology issues such as e-Navigation, Maritime Autonomous Surface Ship (MASS) and Smart ships have constantly emerged in the maritime industry, based on the fourth industrial revolution. The International Maritime Organization is gradually tightening regulations for marine safety and marine environmental protection, and these strengthened regulations are leading to new maritime industries. Thus, the purpose of this study was to design a suitable model to analyze the industrial competitiveness of domestic autonomous operation technology industry, based on the Porter's diamond model. Based on a total of five evaluation factors and 13 detailed factors, the industrial competitiveness of the domestic autonomous operation technology industry was evaluated qualitatively and quantitatively. This industry, which is in the early stage of industrial development, was evaluated as 16.9 points relative to indexing industrial competitiveness. Currently, it is characterized by the simultaneous development of related regulations and core technologies, from the establishment of the scope of the industry. The industrial competitiveness evaluation considering these industrial characteristics is expected to serve as the basis for strategic support and new industrial policy, and impact a wide range of related industries such as shipping, logistics, ports, and shipbuilding and equipment industries.

• Journal of the Korean Applied Science and Technology
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• v.39 no.4
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• pp.552-559
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• 2022

Atopic dermatitis (AD) is a chronic inflammatory skin disease accompanied by severe itching, mainly before five. The aim of this study is to investigate the effects of 405 nm+850 nm LED light therapy on AD-like symptoms in NC/Nga mice. The mice were randomly placed in the normal (Vehicle), atopic dermatitis-induced (CON), and 405 nm + 850 nm LED light therapy (LED) groups. The LED experimental group conducted 405 nm+850 nm wavelength LED ray therapy for 10 minutes a day for seven days. LED light therapy research confirmed the improvement and improvement of Dermatics score and observed the reduction of epidermal tissue thickness caused by dermatitis. Based on the significant decrease of serum IL-1𝛽 and transdermal moisture loss and serum IgE concentration due to LED light therapy, LED light therapy can help restore normal skin conditions in mice that cause atopic dermatitis. This study showed the anti-atopic effect of infrared light and blue light. Light in mice with atopic dermatitis led to the simultaneous use of circular LEDs with two wavelengths.

• Journal of Korea Port Economic Association
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• v.38 no.3
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• pp.87-104
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• 2022

Considering the complex structure and high volatility in the shipping market, it is important to investigate the connectedness amongst influencing factors. This study explores the dynamic relationship between supply-demand factors and shipping freight indices. We choose Capesize and Panamax in the bulk carrier market and use quarterly data of GDP, world fleet, BCI, and BPI from 1999 to 2021. Applying the wavelet analysis and wavelet Granger causality test, the simultaneous examination of co-movement and causality between two factors and the shipping market in both the time and frequency domains is achieved. We find that co-movement and causality vary across time and frequencies, thereby existing dynamic relationships between variables. Second, compared to multiple coherencies using demand and supply factors together, partial coherencies indicate noticeable causalities. It implies that analyzing demand and supply factors separately is essential. Finally, shipping freight indices show a high correlation with the demand factor in a good market and with the supply factor in a bad market. Generally, GDP positively leads shipping freights in the recovery phase while the world fleet negatively leads shipping freights in the downturn. The research is meaningful in that the rarely-applied wavelet analysis is adopted in the shipping market and that it gives a reasonable ground to explain the role of supply and/or demand factors in different phases of the market cycle.

• Korean Journal of Clinical Laboratory Science
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• v.54 no.2
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• pp.103-109
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• 2022

In December 2019, the coronavirus disease 2019 (COVID-19) caused by the virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China and spread rapidly around the world, infecting millions of people. Cases of COVID-19 infection were observed to lead to viral pneumonia. Thirty-five patients admitted to the Gyeonggi Medical Center, South Korea, between November 2020 to January 2021, were found to have been infected with the influenza virus A and B, which cause symptoms similar to COVID-19. The records of these patients and those of COVID-19 patients who visited the hospital for medical examination were compared. The study patients included thirty patients with COVID-19 and/or influenza, five of those with influenza alone. A group of 121 patients without infection was used as control. Patients with COVID-19 and influenza had significantly higher lactate dehydrogenase levels than the patients with COVID-19 alone. The erythrocyte sedimentation rate (ESR) was higher in patients with COVID-19 alone than in other groups. Significant clinical outliers were observed in the COVID-19 and influenza infection group compared with the COVID-19 alone group. These results are expected to play an important role in the analysis of the hematological data of infected patients and the comparison of simultaneous and single infection data to determine clinical symptoms and other signs. These results may also assist in the development of vaccines and treatments for COVID-19.