• 대한치과교정학회지
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• 제35권3호
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• pp.238-249
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• 2005

악골부조화가 심할수록 기능향상을 위해 악골 및 치아 치조부에서의 보상반응이 현저해진다. 대표적인 현상으로 하악과두의 변위와 상악교합평면의 변화 등을 들 수 있다. 이러한 상하악골에서의 적응성 변화는 안모의 심미성과 교합의 기능 향상을 위해, 술후 안정성을 높이기 위해서 악교정수술을 통해 반드시 수정해야 할 요소이다 적절한 상악골 수술을 위해서 통상적으로 model surgery를 시행하여 왔으나 이의 단점을 보완하기 위해 Surgical Jaw Relator를 고안하였으며 이는 교합기의 mounting plate 대신에 부착함으로써 상하악 모형의 삼차원적 이동과 회전이 가능하도록 설계되어 있으며 기존의 모든 종류(Panadent. Sam, Denar, Hanau 등)의 교합기에 손쉽게 부착하여 수술용 스프린트의 제작 시간을 대폭 줄일 수 있는 장점이 있다 상악골 상방 이동이 필요한 하악전돌 증례와 상악골 하방 이동이 요구되는 하악후퇴 증례 등에 본 기구를 적용한 결과 양호한 수술 결과를 얻었으며, 이로써 정교한 상악 수술을 요하거나 명확한 수술 계획이 설정된 증례 등에서 본 기구를 적절하게 사용할 경우 수술용 스프린트를 효율적으로 제작하는데 다소 도움이 될 것으로 생각된다.

• Parasites, Hosts and Diseases
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• 제47권3호
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• pp.227-233
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• 2009

Local malaria transmission in the United Arab Emirates (UAE) came to an end in 1997. Nevertheless, UAE has been subjected to substantial importation of malaria cases from abroad, concerning both UAE nationals and immigrants from malarious countries with a total number of 2,119 cases in 2007. To evaluate a new DNA extraction technique using nested PCR, blood samples were collected from 132 individuals who presented to Infectious Diseases Department in Rashid Hospital, Dubai, and Central Department of Malaria Control with fever and persistent headache. Giemsa-stained blood films and ELISA test for malaria antibodies were carried out for detection of Plasmodium infection. Plasmodium infections were identified with the genus-specific primer set and species differentiation using nested PCR. A rapid procedure for diagnosis of malaria infections directly from dried blood spots using for the first time DNA extract from FTA Elute cards was evaluated in contrast to extraction techniques using FTA classic cards and rapid boiling technique. Our new simple technique for DNA extraction using FTA Elute cards was very sensitive giving a sensitivity of 100% compared to 94% using FTA classic cards and 62% in the rapid boiling technique. No complex preparation of blood samples was required prior to the amplification. The production cost of DNA isolation in our PCR assay was much less incomparable to that of other DNA extraction protocols. The nested PCR detected plasmodial infection and could differentiate P. falciparum from P. vivax, and also detected the mixed infection.

• 한국수자원학회논문집
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• 제41권7호
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• pp.693-700
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• 2008

저류지를 설계함에 있어서 주어진 저류지 제원과 방류시설 제원하에서 저류지 설계모의모형을 이용하여 저류추적 을 실시하는 방법을 대치하고자 저류지의 예비설계 단계에서 저류지 최적계획모형에 의해 산정된 저류용량을 초기 가정치로 사용하거나 개발전후의 첨두유량비인 ${\alpha}$를 사용하여 저류지를 간편설계하기 위한 관련변수 해석을 실시하 였다. 관련변수 해석을 통해 저류지의 유입첨두유량에 대한 저류지 첨두방류량의 비인 첨두유량비 ${\alpha}$와 저류지의 저류비 $S_r$, 저류지의 방류구조 크기 D와 저류지의 최대허용수심 $H_{max}$, 저류지의 구형바닥면적 A'과 저류지의 제형바닥면적 A 및 $A_c$의 관계를 이용하여 저류지를 간편하게 설계하는 간편설계기법의 절차를 제시하였다. 저류지의 간편 설계기법은 도시화로 인한 유출총량 및 첨두유량 증대에 대처하는 방안으로 도시유역에서 유출저감시설로서 신설되는 저류지를 설계함에 있어서 기존의 많은 제반사항과 저류지 추적을 시행하지 않고 간편한 설계를 할 수 있는 방법으로 활용가능하다.

• Clinical and Experimental Reproductive Medicine
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• 제23권1호
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• pp.81-86
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• 1996

The assessment of acrosomal status is important in evaluating the ability of sperm to fertilize the egg. The acrosomal status of sperm from 47 normal volunteers with proven fertility and 167 subfertile men with not to achieve pregnancy for at least 1 year were evaluated with Acrobeads test(FUSO Pharmaceutical Industries, Ltd, Japan) using immunobeads coated with MH61 monoclonal antibody, which is specific for acrosome-reacted sperm. The mean${\pm}$SD of acrobeads score in 47 volunteer group was $2.8{\pm}0.7$, of which 46(97.9%)cases were ${\geq}$ 2. The mean${\pm}$SD of acrobeads score in 167 subfertile group was $1.7{\pm}0.8$, of which 73(79.3%)cases were ${\leq}$ 1. The aerobe ads score in subfertile group were significantly lower(r=0.294, p<0.05) than those in volunteer group. In subfertile group, acrobeads score were well correlated with the sperm density and motility(r=0.275, r=0.281, p<0.01), but not with semen volume(r=0.16) and serum hormone level(FSH r=0.084, LH r=0.036, testosterone r=0.058, prolactin r=0.006 and estradiol r=0.060)(p>0.05). Of 63 subfertile cases with normozoospermia, 22(34.9%)cases showed 0 or 1 of acrobeads score, which means to accompany with a functional defect in spite of normal morphology. As a results, Acrobeads test is not only a technically simple sensitive procedure with good reproducibility in evaluating the sperm fertilizing capacity but also an useful in the evaluation of effectiveness in the treatment of infertility and the separation of acrosome-reacted sperm in the assisted reproductive technique.

• 대한두경부종양학회지
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• 제23권1호
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• pp.32-36
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• 2007

Background and Objective：A post-operative hypertrophic scar of the anterior neck is the leading complaint of the patients who underwent conventional thyroid surgery. In order to minimize the post-operative scar of the anterior neck, we performed thyroidectomy via axillary approach using operating microscope and a specialized retractor to determine technical feasibility. Patients and Methods：From January 2005 to December 2006, we performed thyroidectomy via axillary approach under operating microscope(f=400mm, ${\times}2.5$；OPMI $pico^{(R)}$；Zeiss, Germany) for benign unilateral nodule in 25 cases(all female, average age 34.5yrs). Under general anesthesia less than 7cm of skin incision was made in the axilla of ipsilateral side. A subcutaneous tunnel went over the pectoralis major muscle and the clavicle, and then through the sternocleidomastoid muscle and sternothyroid muscle was excised. The area around the thyroid was sufficiently dissected, and then a retractor designed for exposure via axillary approach was placed within the tunnel and under operating microscope thyroidectomy was performed. Results：There were 17 cases of thyroid nodulectomy and 8 cases of subtotal lobectomy. The mean average operative time was 102.64minutes. Postoperative complications included one case of postoperative bleeding, one case of temporary vocal cord paralysis, two cases of delayed wound healing, two cases of paresthesia of shoulder and arm, and two cases of hypertrophic scar of the axilla. Postoperative histopathology includes 17 cases of adenomatous hyperplasia, six cases of cyst, and two cases of follicular adenoma. For all cases hospitalization period was two days. Conclusion：Thyroidectomy via axillary approach under operating microscope has a good cosmetic advantage without a post-operative scar of the anterior neck. The procedure is simple due to direct vision using operating microscope, easy to identify important structures by magnifying them, and therefore surgical time can be reduced.

• 대한조선학회논문집
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• 제43권5호
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• pp.568-577
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• 2006

With the increase of ship size and speed, the loading on the propeller is increasing, which in turn increases the rotational speed in the propeller slipstream. The rudder placed in the propeller slip stream is therefore subject to severe cavitation with the increased angle of attack due to the increased rotational induction speed of the propeller. In the present paper the surface panel method, which has been proved useful in predicting the sheet cavitation on the propeller blade, is applied to solve the cavity boundary value problem on the rudder. The problem is then solved numerically by discretizing the rudder and cavity surface elements of the quadrilateral panels with constant strengths of sources and dipoles. The strengths of the singularities are determined satisfying the boundary conditions on the rudder and cavity surfaces. The extent of the cavity, which is unknown a priori, is determined by iterative procedure. Series of numerical experiments are performed increasing the degree of complexity of the rudder geometry and oncoming flows from the simple hydrofoil case to the real rudder in the circumferentially averaged propeller slipstream. Numerical results are presented with experimental results.

• 한국연초학회지
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• 제30권1호
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• pp.1-7
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• 2008

Bacterial wilt caused by Ralstonia solanacearum has become a severe problem on tobacco in Korea. No effective single control measure is available at present time. One of the most potential way for controlling the bacterial wilt on tobacco is growing tobacco cultivars resistant to the bacterial wilt. In this study, optimal conditions for screening tobacco cultivars resistant to the bacterial wilt were examined to provide reproducible and efficient methods in growth chamber testing and field experiments for evaluating plant disease resistance. For this, already-known inoculation methods, inoculum densities, and incubation temperature, and plant growth stages at the time of inoculation were compared using tobacco cultivars resistant (Nicotiana tabacum cv, NC95), moderately resistant (N. tabacum cv. SPG70), and susceptible (N. tabacum BY4) to the bacterial disease. It was determined that root-dipping of tobacco seedlings at six true leaf stage into the bacterial suspension with inoculum level of $10^8$ colony-forming units (CFU)/ml for 20 min before transplanting was simple and most efficient in testing for resistance to the bacterial wilt of tobacco caused by R. solanacearum, for which disease incidences and severities were examined at 2 weeks of plant growth after inoculation at $20{\sim}25^{\circ}C$ in a growth chamber. These experimental conditions could discriminate one tobacco cultivar from the others by disease severity better than any other experimental conditions. In field testing, the optimum time for examining the disease occurrence was late June through early July. These results can be applied to establishing a technical manual for the screening of resistant tobacco cultivars against the bacterial wilt caused by R. solanacearum.

• 대한조선학회논문집
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• 제35권2호
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• pp.20-28
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• 1998

몰수체의 운동을 정확하게 예측하기 위해서는 동적 모형의 비선형 구조를 선택하고, 이에 해당하는 조종계수를 모형 시험을 통해 추정하여야 한다. 모형 구조가 주어지면 조종계수들의 값만이 미지수가 되어 추정은 표준 최소 자승 문제로 정식화될 수 있다. 불행하게도 몰수체들의 비선형모형 구조는 거의 알려지지 않고 있다. 따라서, 모형 시험에서 측정된 자료들로부터 운동 방정식의 구조를 결정하는 방법을 개발하여 계수 추정 절차에 중요한 한 부분으로 포함시켜야 한다. 본 연구에서는 모형 시험 결과 해석을 위해 널리 사용되고 있는 최소 자승 알고리즘과 그 성능평가법에 대해 살펴보고, Gram-Schmidt에 의한 직교 분리법에 기초를 둔 계수 식별 알고리즘을 매우 단순하고 효과적으로 구조 선택법과 계수 추정법을 결합할 수 있도록 확장하였다. 마지막으로 시뮬레이션과 실제 몰수체에 대한 모형 시험 자료로의 적용을 통해 이 기법의 성능을 검증하였다. 결론적으로 본 연구의 방법은 모형 시험 결과로부터 효율적으로 운동 방정식의 구조를 식별하고 조종 계수를 추정함을 확인하였다.

• 한국임상수의학회지
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• 제10권2호
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• pp.237-242
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• 1993

Combined intramuscular administration of ketamine 8mg/kg. xylazine 2mg/kg were done to evaluate effect of anesthesia in Siberian tiger White tiger and Bengal tiger. Mean induction time(MIT), mean arousal time-(MAT). mean walking time(MWT) and clinical sign were evaluated. The results were as follows. MIT were taken 16.1$\pm$3.5 minutes for Siberian tiger. 15.5$\pm$2.4 minutes for White tiger and 12.3$\pm$2.5 minutes for Bengal tiger. MAT were taken 44.2$\pm$9.5 minutes for Siberian tiger, 48.3$\pm$8.6 minutes for White tiger and 58.7$\pm$5.8 minutes for Bengal tiger. MWT were taken 110.6$\pm$11.6 minutes for Siberian tiger, 106.7$\pm$13.1 minutes for White tiger and 99.6$\pm$10.2 minutes for Bengal tiger. Nausea. vomiting. salivation. severe convulsion. sudden decreased respiration and dyspnea were observed in Siberian tiger during sedation and anesthesia. Also, nausea, vomiting, salivation and convulsion were observed in White tiger and Bengal tiger but the clinical signs were more mild than Siberian tiger. The Bengal tiger which used combined ketamine 5mg/kg , xylazine 1mg/kg were shown reduced induction time compare with combined administration ketamine 8mg/kg, xylazine 2mg/kg in Bengal tiger as 10.8$\pm$32 minutes for MIT. 32.3$\pm$4.3 minutes for MAT and 78.5$\pm$7.3 minutes for MWT Vomiting and convulsion were observed during induction time but there were no nausea and salivation. The present results suggested that preventive methods against severe convulsion and dyspnea should be required in Siberian tiger when combined anesthesia of ketamine 8mg/kg, xylazine 2mg/kg used. Combined anesthesia of ketamine 5mg/kg, xylazine 1mg/kg in Bengal tiger might be very effective for simple surgical procedure and diagnosis.

• 한국수자원학회논문집
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• 제37권5호
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• pp.437-448
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• 2004

수문학 교과서를 통해 널리 알려진 기존의 유역중심 DAD 분석방법은 유역면적이 작거나 호우이동이 거의 없는 경우에 매우 유용한 방법으로 계산이 비교적 간단하다. 그러나, 태풍과 같이 호우이동이 뚜렷한 경우에는 DAD 관계를 명확히 표현하기 어려우며, 특히 유역면적이 증가함에 따라 평균면적강우량의 오차도 증가하므로, 분석자의 혼란을 야기시킬 수 있다. 이에 본 연구에서는 기존의 유역중심 DAD 분석방법의 단점을 보완코저 호우중실 DAD 분석방법을 개발하였고, 객관적인 DAD 분석결과를 얻기 위해 이를 프로그램화하였다. 관측강우량을 이용하여 기존의 방법과 비교ㆍ검토를 수행한 결과 제안된 방법이 평균면적강우량을 보다 적절하게 표현함을 알 수 있었다. 따라서 개발된 프로그램을 이용하여 우리나라의 전국단위 호우분석(1969년부터 1999년까지 약 130여개 호우)을 수행하였으며, 그 결과를 유역중심 DAD 분석결과와 비교ㆍ검토하였다.