• The Korean Journal of Community Living Science
• /
• v.28 no.1
• /
• pp.131-141
• /
• 2017

This study was carried out to perform genotoxicological safety evaluation of crude antifungal compounds produced by Bacillus subtilis SN7 (B. subtilis SN7) isolated from meju. Bacterial reverse mutation assay with Salmonella typhimurium TA98, TA100, TA1535, and TA1537 or Escherichia coli WP2uvrA in the presence and absence of the S9 metabolic activation system was carried out, and the crude antifungal compounds produced by B. subtilis SN7 showed no significant increase in the number of revertant colonies. In the chromosomal aberration tests using Chinese hamster lung (CHL) cells, sample treatment groups showed no increase in the frequency of chromosome aberrations compared to the negative control group. Furthermore, in the micronucleus formation test, the crude antifungal compounds showed no significance increase in the frequency of polychromatic erythrocytes with micronuclei. These results suggest that the crude antifungal compounds produced by B. subtilis SN7 isolated from meju showed no harmful genotoxic effects.

• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.12
• /
• pp.7355-7358
• /
• 2013

Several lines of evidence support the notion that MUC1 is often aberrantly expressed in gastric cancer, and it is a ligand for Helicobacter pylori. Genetic variation in MUC1 gene may confer susceptibility to H. pylori infection and gastric cancer. We assessed the association of common polymorphisms in MUC1 gene with H. pylori infection and non-cardia gastric cancer using an LD-based tag SNP approach in north-western Chinese Han population. A total of four SNPs were successfully genotyped among 288 patients with non-cardia gastric cancer and 281 age- and sex-matched controls. None of the tested SNPs was associated with H. pylori infection. SNP rs9426886 was associated with a decreased risk of non-cardia gastric cancer, but lost significance after adjustment for multiple testing. Overall, our data indicated that common genetic variations in MUC1 gene might not make a major contribution to the risk of H. pylori infection and non-cardia gastric cancer in our studied population.

• The Journal of Advanced Prosthodontics
• /
• v.5 no.4
• /
• pp.423-427
• /
• 2013

PURPOSE. This study evaluated the bond strength between porcelain denture teeth (Bioblend 43D) and four different polymerized denture resins (Lucitone 199, Palapress, Acron MC, Triad) with and without a bonding agent and after four different types of surface treatment (polished, HF etched, sandblasted, air-abraded). MATERIALS AND METHODS. Central incisor porcelain denture teeth were divided into 32 groups of 5 each. Tensile bond strength (MPa) was determined using a testing machine at crosshead speed of 0.5 mm/min. Mean and standard deviation are listed. Data were analyzed by two-way ANOVA. Means were compared by Tukey-Kramer intervals at 0.05 significance level. RESULTS. All surface treatment increased bond strength compared to polished surface and the highest bond strength was found with Palapress resin with etched porcelain surface (8.1 MPa). Bonding agent improved the bond strength of all denture resins to porcelain teeth. Superior bonding was found with Palapress and air-abraded porcelain (39 MPa). CONCLUSION. Resins with different curing methods affect the bond strength of porcelain teeth to denture bases. Superior bonding was found with auto-polymerized resin (Palapress). Application of ceramic primer and bonding agent to porcelain teeth with and without surface treatment will improve the bond strength of all denture resins to porcelain teeth.

• Journal of the Korean Home Economics Association
• /
• v.27 no.4
• /
• pp.139-150
• /
• 1989

The present study was designed to answer the following questions: 1) Is there and relationship between the adolescent's sex role identity and perceived parent behavious? 2) Is there any gender differences in perceived parent behavious? 3) Is there any interaction effect between sex role identity and gender in perceived parent behaviors? 109 male and 101 female undergraduates from the five universities in Seoul served as subjects in this investigation. Subjects were administered the Parent Behavior From (PBF) and the Bem Sex Role Inventory (BSRI) in counterbalanced order. A4 (sex-role identity)×2(gender) multivariate analysis of variance was performed for the perceived paternal and maternal behaviors separately. The simultaneous confidence intervals for pairwise comparison were followed when the MANOVA was significant. In testing all hypotheses, .05 was used as a significance level in this study. For the perceived paternal behavious, 1) The androgynous group, compared with the undifferentiated group, reported greater father warmth, active involvement, greater encouragement of cognitive independence, cognitive curiosity, cognitive competence, achievement control, and conformity. 2) The androgynous individuals showed higher father warmth, congitive independence, curiosity, and cognitive competence than the feminine individuals. 3) The androgynous individuals were found to have significantly higher father warmth than the masculine individuals. For the perceived maternal behaviors, there was a significant difference between gender groups in conformity. Daughters reported higher conformity than sons. The interaction effect between sex-role identity and gender, however, was not found to be significant.

• Journal of Korean Academy of Nursing
• /
• v.27 no.3
• /
• pp.705-714
• /
• 1997

This study was conducted to test validity of related factors and characteristics of 98 Nursing Diagnosis identified in a previous study by the Korean Nurses Association. Data for this study was collected from 892 nurses in eight teaching hospitals located in Seoul using a cross sectional survey method. Each participating hospital was asked to produce at least 10 cases for every nursing diagnosis. There were 7,422 responses out of a possible 7,840. Out of the 7,422 responses 26 were discarded due to incompleteness. Data were analyzed using SAS. The result of the study shows that most of the related factors and characteristics for each of the 98 nursing diagnosis were ranked at more than 3.5 point out of 5 point Likert scale in terms of significance. Through this study the related factors and characteristics of the 98 nursing diagnosis identificance. Through this study the related factors and characteristics of the 98 nursing diagnosis identified through literature review were validated by experts in nursing diagnosis. These validated related factors and characteristics will be utilized for computerization of the nursing diagnosis process.

• ETRI Journal
• /
• v.20 no.1
• /
• pp.55-73
• /
• 1998

In this paper we analyze the technological accumulation processes in the Korean semiconductor industry from the institutional approach. Institutional approach, which is closely connected with Neo-Schumpeterian tradition, has emerged as an alternative theoretical framework to neoclassical approach to understand the process of producing technological knowledge. Traditional wisdom of neoclassical approach revealed the limitation to explain the complex nature of knowledge creation and diffusion. US patent data are analyzed in terms of the increasing trend of numbers and its content to measure the rate and direction of technological capability accumulation. This analysis shows that semiconductor technologies are one of the fastest growing fields among Korean technological activities. Moreover, the analysis of patent content suggests that fabrication technologies are the most important area within the technological development of semiconductors, whilst circuit design and testing technologies are beginning to increase in significance. In addition, it is examined how private sectors and public institutions have contributed to generate technological capabilities, and the relationship between them has been changed during the development processes. It is found that Korean firms enhanced their technological capabilities from the learning and assimilation of imported technology to enhanced in-house R&D capabilities in the later stage. The support of public institution and government policy also played significant role to this successful transformation in conjunction with vigorous R&D investment of public sector.

• International Journal of Highway Engineering
• /
• v.19 no.1
• /
• pp.73-80
• /
• 2017

PURPOSES : This paper presents a comparison study between dynamic and static analyses of falling weight deflectometer (FWD) testing, which is a test used for evaluating layered material stiffness. METHODS: In this study, a forward model, based on nonlinear subgrade models, was developed via finite element analysis using ABAQUS. The subgrade material coefficients from granular and fine-grained soils were used to represent strong and weak subgrade stiffnesses, respectively. Furthermore, the nonlinearity in the analysis of multi-load FWD deflection measured from intact PCC slab was investigated using the deflection data obtained in this study. This pavement has a 14-inch-thick PCC slab over fine-grained soil. RESULTS: From case studies related to the nonlinearity of FWD analysis measured from intact PCC slab, a nonlinear subgrade model-based comparison study between the static and dynamic analyses of nondestructive FWD tests was shown to be effectively performed; this was achieved by investigating the primary difference in pavement responses between the static and dynamic analyses as based on the nonlinearity of soil model as well as the multi-load FWD deflection. CONCLUSIONS : In conclusion, a comparison between dynamic and static FEM analyses was conducted, as based on the FEM analysis performed on various pavement structures, in order to investigate the significance of the differences in pavement responses between the static and dynamic analyses.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.7
• /
• pp.3427-3430
• /
• 2012

Aim: The significance of the mucinous adenocarcinoma in TNM staging and prognosis for colorectal tumor patients is still controversial. The aim was to provide a meta-analysis for TNM staging and prognostic features of colorectal tumors. Methods: 30 individual case-control studies were finally included into this meta-analysis, involving a total of 444,489 cancer cases and 45,050 mucinous adenocarcinomas, of relations with TNM staging and prognostic features. Results: Compared to non-mucinous adenocarcinoma patients, the TNM IV stage accounted for a larger percentage of mucinous adenocarcinomas (OR=1.48, 95%CI 1.28-1.71, POR<0.001) and the prognosis was significantly poor (HR=1.06, 95%CI 1.04-1.08, P<0.001). After heterogeneity testing, the results was similar to the holistic approach outcome (HR=1.48, 95%CI 1.35-1.62, P<0.001). Conclusion: Compared to patients with non-mucinous adenocarcinomas, mucinous adenocarcinoma patients with later TNM staging make up a big percentage, and mucinous adenocarcinoma is an independent risk factor for poor prognosis.

• The Journal of Asian Finance, Economics and Business
• /
• v.4 no.4
• /
• pp.51-60
• /
• 2017

India is the top recipient of workers' remittance flows; recent data indicate that the Remittances/GDP ratio has increased from 2.7% in 2000 to 3.36% in 2015. We apply a consumption behavior model, based on the "permanent income hypothesis", to estimate the consumption augmentation and the stability impact for the period of 1989-2014. The independent variables are: (i) real per capita income (exclusive of remittances) is the measure of "permanent income", (ii) remittances is the measure of "transitory income", and (iii) real interest rate as the indicator of consumers' ability for intertemporal consumption. The economic ramifications are important since current global risk factors could decrease flows in the future. The results indicate the significance of all three variables; there are: (i) evidence of significant consumption augmentation, (ii) consumption responds higher to remittances than to real income, the remittance elasticity is 0.571 and the income elasticity is 0.31, and (iii) evidence of pro-cyclical effect. The VAR model indicates some linkages and causality in the series that result in small response to the shocks. Policies to increase or stabilize remittance flows and to leverage remittances for economic development are important.

• Journal of Oral Medicine and Pain
• /
• v.24 no.2
• /
• pp.181-187
• /
• 1999

The most important progress in diagnostic sciences is the increased sensitivity and specificity in diagnostic procedures due to the development of newer micromethodologies and increasing availability of immunological and molecular biological reagents. The outcome of researches in this field has already provided DNA probes and antibodies which can be used for diagnosing various kinds of diseases including inherited ones. This development can be also applied to diagnose diseases in oral and maxillofacial regions. Technological advances have yielded highly sensitive test methodologies so that low analyte concentration and small sample volume are no longer limiting factors. Therefore, saliva can be useful test fluid for an array of analytes. Salivary constituents of diagnostic significance include steroid hormones, antibodies, drugs, and tumor markers. Of the proteins present in saliva, viral-specific immunoglobulins are of the greatest diagnostic interest. The development of conjugates and antigens by recombinant DNA technique and peptide synthesis is necessary for clinical application. Several kits developed for the purpose of blood testing should be modified to permit their application to saliva. The final practical outcome of researches in diagnostic sciences will be various diagnostic agents which can be used for detection of bacteria and viruses, screening and diagnosis of diseases, genetic screening for forensic individual identification. For these purposes, collaboration researches and development between institutions and companies are essential.