• 제어로봇시스템학회:학술대회논문집
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• 2003.10a
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• pp.955-959
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• 2003

A technique for realizing linear phase IIR filters has been proposed by Powell-Chau which gives a real-time implementation of H(z-1).H(z), where H(z) is a causal nonlinear phase IIR filter. Powell-Chau system is linear but not timeinvariant system. Therefore, that system has group delay response that exhibits a minor sinusoidal variation superimposed on a constant value. In the signal processing, this oscillation seriously degrade the signal quality. Unfortunately, that system has a large sample delay of 4L and also more computational complexity. Proposed system is present a reduced computational complexity technique by moved the numerator polynomial of H(1/z) out to cascade with causal filter H(z) and remain only all-pole of H(1/z), then applied truncated infinite impulse response to finite with truncated IIR filtel $H_L$(z) and L sample delay to subtract the output sequence from the top and bottom filter. Proposed system is linear time invariance and group delay response and total harmonic distortion are also improved.

• Journal of the Institute of Convergence Signal Processing
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• v.2 no.2
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• pp.95-102
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• 2001

Fuzzy system is capable of uniformly approximating any nonlinear function over compact input space. The applications of fuzzy system, however, have been primarily limited by the need for large number of fuzzy rules, in particular, for the high-order nonlinear system. In this paper, we propose the reconstruction methods of fuzzy systems, parallel type and cascade, based on the decomposition of some classes of high-order nonlinear functions. Using the both types appropriately, we can reduce the number of fuzzy rules geometrically. It can be applied to the fuzzy system that has an online adaptive structure. Two examples of adaptive fuzzy sliding mode control are shown in the computer simulations to verify the validity of the proposed algorithm.

• Molecules and Cells
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• v.20 no.2
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• pp.280-287
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• 2005

The insulin-mediated Ras/mitogen-activated protein (MAP) kinase cascade was examined in SK-N-BE(2) and PC12 cells, which can and cannot produce reactive oxygen species (ROS), respectively. Tyrosine phosphorylation of the insulin receptor and insulin receptor substrate 1 (IRS-1) was much lower in SK-N-BE(2) cells than in PC12 cells when the cells were treated with insulin. The insulin-mediated interaction of IRS-1 with Grb2 was observed in PC12 but not in SK-N-BE(2) cells. Moreover, the activity of extracellular-signal-related kinase (ERK) was much lower in SK-N-BE(2) than in PC12 cells when the cells were treated with insulin. Application of exogenous $H_2O_2$ caused increased tyrosine phosphorylation and Grb2 binding to IRS-1 in SK-N-BE(2) cells, while exposure to an $H_2O_2$ scavenger (N-acetylcysteine) or to a phophatidylinositol-3 kinase inhibitor (wortmannin), and expression of a dominant negative Rac1, decreased the activation of ERK in insulin-stimulated PC12 cells. These results indicate that the transient increase of ROS is needed to activate ERK in insulin-mediated signaling and that an inability to generate ROS is the reason for the insulin insensitivity of SK-N-BE(2) cells.

• Journal of Power Electronics
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• v.17 no.3
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• pp.704-715
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• 2017

For three-phase synchronization applications, the synchronous reference frame phase-locked loop (SRF-PLL) is probably the most widely used technique due to its ease of implementation and satisfactory phase tracking performance under ideal grid conditions. However, under unbalanced and distorted grid conditions, its performance tends to worsen. To deal with this problem, a variety of filtering stages have been proposed and used in SRF-PLLs for the rejection of disturbance components at the cost of degrading the dynamic performance. In this paper, to improve dynamic performance without compromising the filtering capability, an effective hybrid filtering stage is proposed and incorporated into the inner loop of a quasi-type-1 PLL (QT1-PLL). The proposed filtering stage is a combination of a moving average filter (MAF) and a modified delay signal cancellation (DSC) operator in cascade. The time delay caused by the proposed filtering stage is smaller than that in the conventional MAF-based and DSC-based PLLs. A small-signal model of the proposed PLL is derived. The stability is analyzed and parameters design guidelines are given. The effectiveness of the proposed PLL is confirmed through experimental results.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.18 no.6
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• pp.195-200
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• 2018

A W-band frequency octupler is implemented on 100-nm GaAs pHEMT process. The fabricated octupler can be used as a local oscillator or a signal source of W-band transceivers. Three common-source doublers are connected in cascade to multiply an input signal of 10.75 GHz to 83 GHz. A common-source amplifier is followed for each doubler to improve the conversion gain and suppress the unwanted harmonics. The fabricated octupler showes high output of more than 6 dBm in the 80 - 84 GHz band and achieved excellent spurious suppression performance over 20 dBc.

• Proceedings of the Korean Society of Plant Pathology Conference
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• 2003.10a
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• pp.99.1-100
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• 2003

E. intermedium Blocontrol activity of a P. chlororaphis rhizobacteium O6, depends to the synthesis of extracellular secondary metabolites and exoenzymes, thought to antagonize the pathogenicity of a variety of phytopathogenic fungi. The production of secondary metabolites and exoenzymes in O6, depends essentially on the GacS-mediated signal transduction pathway, which activates largely unknown signal transduction pathway. To exploit the GacS-mediated signal transdcution pathway involved in activation of ph genes that are necessary for biosynthesis of phenazine from P. chlororaphis O6, we cloned and sequenced the phz operon, rpoS gene encoding stationary specific sigma factor, ppx gene encoding polyphosphatase, and lon gene encoding ion protease. Expression of each gene in wild type and GacS mutant were analyzed by RT-PCR. Transcripts from rpoS, phzI enconing acylhomoserine lactone (AHL) synthase, and ph structural genes in the GacS mutant were reduced in each of these growth phases compared to the wild type. The GacS or Lon mutant was found to be deficient in the production of phenzines, exoenzymes, and the acylhomoserine lactone. These mutants were not complemented by ph operon and addition of exogenous AHL. These results indicate that the GacS global regulatory systems controls phenazine production at multiple levels. Future research will focus to identifying the GacS-mediated regulatory cascade involving in production of phenazine in P. chlororaphis.

• Archives of Pharmacal Research
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• v.25 no.5
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• pp.561-571
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• 2002

The action mechanisms of several chemopreventive agents derived from herbal medicine and edible plants have become attractive issues in cancer research. Tea is the most widely consumed beverage worldwide. Recently, the cancer chemopreventive actions of tea have been intensively investigated. It have been demonstrated that the active principles of tea were attributed to their tea polyphenols. Recently, tremendous progress has been made in elucidating the molecular mechanisms of cancer chemoprevention by tea and tea polyphenols. The suppression of various tumor biomarkers including growth factor receptor tyrosine kinases, cytokine receptor kinases, P13K, phosphatases, ras, raf, MAPK cascades, NㆍFB, IㆍB kinase, PKA, PKB, PKC, c-jun, c-fos, c-myc, cdks, cyclins, and related transducing proteins by tea polyphenols has been studied in our laboratory and others. The IㆍB kinase (IKK) activity in LPS-activated murine macrophages (RAW 264.7 cells) was found to be inhibited by various tea polyphenols including (-) epigallocatechin-3-gallate (EGCG), theaflavin (TF-1), theaflavin-3-gal-late (TF-2) and theaflavin-3,3'-digallate (TF-3). TF-3 inhibited IKK activity in activated macrophages more strongly than did the other tea polyphenols. TF-3 inhibited both IKK1 and IKK2 activity and prevented the degradation of IㆍBㆍand IㆍBㆍin activated macrophage cells. The results suggested that the inhibition of IKK activity by TF-3 and other tea polyphenols could occur by a direct effect on IKKs or on upstream events in the signal transduction pathway. TF-3 and other tea polyphenols blocked phosphorylation of IB from the cytosolic fraction, inhibited NFB activity and inhibited increases in inducible nitric oxide synthase levels in activated macrophage. TF-3 and other tea polyphenols also inhibited strongly the activities of xanthine oxidase, cyclooxygenase, EGF-receptor tyrosine kinase and protein kinase C. These results suggest that TF-3 and other tea polyphenols may exert their cancer chemoprevention through suppressing tumor promotion and inflammation by blocking signal transduction. The mechanisms of this inhibition may be due to the blockade of the mitogenic and differentiating signals through modulating EGFR function, MAPK cascades, NFkB activation as wll as c-myc, c-jun and c-fos expression.

• 제어로봇시스템학회:학술대회논문집
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• 1997.10a
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• pp.593-596
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• 1997

This paper is concerned with the properties of zeros of discrete-time systems which are composed of a hold, a continuous-time plant and a sampler in cascade. Here the signal reconstruction is based on the fractional order hold. In order to overcome the implementing problem of the fractional order hold, the piecewise constant reconstruction method by use of the zero order hold is introduced. The properties of the zeros are explored in the limiting cases when the sampling period tends to zero. The stability conditions of the zeros for sufficiently small sampling periods are also presented.

• Proceedings of the IEEK Conference
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• 2005.11a
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• pp.861-864
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• 2005

Performing accurate and repeatable low frequency noise measurement is critical for modeling and simulation of flicker noise. Through the accurate and repeatable on-wafer measurement, low frequency noise characteristics of the 0.18 ${\mu}m$ n-MOSFETs are discussed. And on-wafer flicker noise measurement system is presented. The on-wafer measurement system consists of cascade probe station, low noise current amplifier (SR570), and dynamic signal analyzer (HP35670A).

• Proceedings of the IEEK Conference
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• 2001.09a
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• pp.553-556
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• 2001

본 논문은 불완전한 휘도/색신호 분리로 인해 복조된 NTSC 칼라 TV신호의 휘도와 색차신호의 경계(edge)에서 나타나는 dot 패턴을 제거하는 2차원 필터에 대한 것이다. 제안된 필터는 휘도와 색차신호의 천이영역 검출신호와 dot 패턴 검출신호에 따라 직렬(cascade)로 연결된 수평-수직방향 저역통과필터의 차단주파수를 조절함으로써 dot 패턴을 감소시킨다. 제안 방식의 성능을 검증하기 위하여 현재 가장 많이 사용되는 NTSC 디코더 칩인 BT835과 SAA7113H을 이용하여 복조된 휘도와 색차신호에 적용한 결과 영상신호가 변화를 갖는 경계 영역에서 발생한 dot 패턴과 불완전한 복조로 인해 발생하는 평탄영역에서의 dot 패턴이 제거되었음을 확인할 수 있었다.