• Title/Summary/Keyword: search area analysis

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Screening for candidate genes related with histological microstructure, meat quality and carcass characteristic in pig based on RNA-seq data

  • Ropka-Molik, Katarzyna;Bereta, Anna;Zukowski, Kacper;Tyra, Miroslaw;Piorkowska, Katarzyna;Zak, Grzegorz;Oczkowicz, Maria
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.10
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    • pp.1565-1574
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    • 2018
  • Objective: The aim of the present study was to identify genetic variants based on RNA-seq data, obtained via transcriptome sequencing of muscle tissue of pigs differing in muscle histological structure, and to verify the variants' effect on histological microstructure and production traits in a larger pig population. Methods: RNA-seq data was used to identify the panel of single nucleotide polymorphisms (SNPs) significantly related with percentage and diameter of each fiber type (I, IIA, IIB). Detected polymorphisms were mapped to quantitative trait loci (QTLs) regions. Next, the association study was performed on 944 animals representing five breeds (Landrace, Large White, Pietrain, Duroc, and native Puławska breed) in order to evaluate the relationship of selected SNPs and histological characteristics, meat quality and carcasses traits. Results: Mapping of detected genetic variants to QTL regions showed that chromosome 14 was the most overrepresented with the identification of four QTLs related to percentage of fiber types I and IIA. The association study performed on a 293 longissimus muscle samples confirmed a significant positive effect of transforming acidic coiled-coil-containing protein 2 (TACC2) polymorphisms on fiber diameter, while SNP within forkhead box O1 (FOXO1) locus was associated with decrease of diameter of fiber types IIA and IIB. Moreover, subsequent general linear model analysis showed significant relationship of FOXO1, delta 4-desaturase, sphingolipid 1 (DEGS1), and troponin T2 (TNNT2) genes with loin 'eye' area, FOXO1 with loin weight, as well as FOXO1 and TACC2 with lean meat percentage. Furthermore, the intramuscular fat content was positively associated (p<0.01) with occurrence of polymorphisms within DEGS1, TNNT2 genes and negatively with occurrence of TACC2 polymorphism. Conclusion: This study's results indicate that the SNP calling analysis based on RNA-seq data can be used to search candidate genes and establish the genetic basis of phenotypic traits. The presented results can be used for future studies evaluating the use of selected SNPs as genetic markers related to muscle histological profile and production traits in pig breeding.

The Effects of Strength Note Program on Mental Health of University Students in Convergence Age (강점노트 프로그램이 융복합시대 대학생의 정신건강에 미치는 영향)

  • Lee, Ye-Jong;Park, Sung-Joo
    • Journal of Digital Convergence
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    • v.13 no.7
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    • pp.223-228
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    • 2015
  • This study aims to verify the effect of the strength note program by comparing and analyzing the effect of the strength note program on self-esteem and self-efficacy of university students in Convergence Age. This study targeted 70 male and female university students in G area and the subjects were asked to find their and other people's positive characteristics or strengths once a week and record them. For analysis of the collected data, frequency and percentage analysis and paired-t-test were conducted using SPSS WIN 20.0. As the result, the strength note program significantly influenced the improvement in self-esteem and self-efficacy of university students. This result demonstrates the necessity of the strength note program for improving self-esteem and self-efficacy of university students. Therefore, there is a need to provide a specific and systematic strength note program to help university students get over diverse problems. It is considered that this will help mental health, academic achievement and career search of university students and contribute to the enhancement in happiness and the quality of life. Also it will be the basis for future longitudinal studies through interdisciplinary convergency research.

A Survey Study on University Students' Recognition for The Disabled - Focusing on Universities in Chungcheong Province (대학생의 장애인에 대한 인식에 관한 조사연구 - 충청도 대학을 중심으로 -)

  • Jeon, Mi-Young;Lee, Han-Woo
    • Journal of Convergence for Information Technology
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    • v.7 no.5
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    • pp.1-13
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    • 2017
  • It is revealed that there are more registered disabled people in our country who have their disability because of acquired factors such as accidents than because of innate deformity. This phenomenon will continue and the incidence of acquired disability will increase more and more. Even though there is noticeable change, the social recognition toward the disabled is still negative. Particularly, university students are in the early adulthood according to the development of life-cycle, and this is the period that people have diverse social relationships, depart from unified frame and work in various fields, and set up their own thoughts and ideology with knowledge and skills acquired from university education. Therefore, in this study, we are going to search the recognition of the university students, who are in the previous period of entering into the society, toward the disabled, and if they have negative prejudice or attitude against the disabled, we are going to find the ways to improve on their awareness positively. The subjects of the survey were randomly selected among 230 out of total 250 students by visiting thirteen universities in Chungcheong Province, and were analyzed by using SPSS (ver. 18.0) program. T-test and One-way ANOVA were used as analytical methods to look into the difference of analysis of frequency, descriptive statistic, reliability analysis and attitudes for comprehending sociodemographic characteristics of the subjects of the survey. In conclusion, it has to be not a temporary or event-like training, but a training that makes people have positive recognition and attitude towards accurate information, knowledge, human rights, disability, and diversity. This thesis has a limitation to be generalized to the university students all over the country since the region is limited to a certain area.

Factors Influencing The Perception of Continuing Medical Education for Radiological Technologist (방사선사 보수교육 인식에 영향을 미치는 요인)

  • Yang, Sung-Hee;Lee, Dong-Yeon
    • The Journal of the Korea Contents Association
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    • v.21 no.7
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    • pp.629-636
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    • 2021
  • The study analyzes the relationship between demand, satisfaction, and perception for non-face-to-face continuing medical education(CME) conducted in 2020 for 225 radiological technologist license holders working in the Busan area, and the factors that influence the positive perception of CME. T-test and one way ANOVA were used, and stepwise multiple regression analysis was performed. As a result, there were high demands for mobile publicity, professional radiological technologist, educational expenses support from institution heads, and CME. Male radiological technologist, over 50 years of age, and the more experienced they had a job chance, the more they had a positive perception. In the correlation between variables, the perception of the education system and the need for education showed a positive correlation. The higher the satisfaction with the education system, the higher the perception of the need for education. About 53% of the content was satisfied. Therefore, in order to raise awareness of CME, it is considered that policy changes to the education system are necessary first of all. It is considered that the search for the development of education content and educational content is necessary above all.

Social Determinants of Health of Multicultural Adolescents in South Korea: An Integrated Literature Review (2018~2020) (국내 다문화 청소년의 사회적 건강결정요인: 통합적 문헌고찰(2018~2020))

  • Kim, Youlim;Lee, Hyeonkyeong;Lee, Hyeyeon;Lee, Mikyung;Kim, Sookyung;Kennedy, Diema Konlan
    • Research in Community and Public Health Nursing
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    • v.32 no.4
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    • pp.430-444
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    • 2021
  • Purpose: This study is an integrated literature review to analyze health problems and social determinants of multicultural adolescents in South Korea. Methods: An integrative review was conducted according to Whittemore & Knafl's guideline. An electronic search that included publications from 2018 to 2020 in the PubMed, EMBASE, Cochrane Library, CINAHL, RISS, and KISS databases was conducted. Of a total of 67 records that were identified, 13 finally met full inclusion criteria. Text network analysis was also conducted to identify keywords network trends using NetMiner program. Results: The health problems of multicultural adolescents were classified into mental health (depression, anxiety, suicide and acculturative stress) and health risk behaviors (smoking, risky drinking, smartphone dependence and sexual behavior). As social determinants affecting the health of multicultural adolescents, the biological factors such as gender, age, and visible minority, and the psychological factors such as acculturative stress, self-esteem, family support, and ego-resiliency were identified. The sociocultural factors were identified as family economic status, residential area, parental education level, and parents' country of birth. As a result of text network analysis, a total of 41 words were identified. Conclusion: Based on these results, mental health and health risk behaviors should be considered as interventions for health promotion of multicultural adolescents. Our findings suggest that further research should be conducted to broaden the scope of health determinants to account for the effects of the physical environment and health care system.

Transition Program for Youth With Disabilities: Research Trend Analysis and Systematic Review (장애청소년의 전환프로그램 : 연구 동향 분석과 체계적 고찰)

  • An, Su-bin;Park, Hae Yean
    • Therapeutic Science for Rehabilitation
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    • v.11 no.3
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    • pp.23-36
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    • 2022
  • Objectives : This study aimed to provide basic data on intervention strategies that occupational therapists can access by systematically analyzing the intervention and effectiveness for youth with disabilities. Methods : The RISS, PubMed, and Web of Science databases were used to search for papers published between 2006 and 2021. The keywords were "Disability AND Adolescents OR Young adult AND Transition education OR Transition program". Seven papers were selected for analysis, and the full text was reviewed. The keywords and national relations were analyzed and visualized using the WoS (Web of Science) and VOSviewer programs. Results : The participants were classified into five types (ASD or ADHD, ID, DD, and physical disability). The areas used for the intervention were mixed into three categories: occupation (academic), self-management (time), and interaction (personal relations and communication). Sociality and adaptation, quality of life, and at least one of the three categories of daily life activities showed significant improvement. Conclusions : This study can be used as basic data to expand the area where only OTs can contribute while grasping the research trend of the conversion program and presenting the direction of exchange with various experts by organizing the application and its effects.

Use of Multimedia Technologies in Extra-Curricular Works in Order to Improve the Quality of Training of Future Specialists

  • Tverezovska, Nina;Kovbasa, Tetiana;Pryhalinska, Tetiana;Mykhniuk, Serhii;Lopushan, Tetiana;Radionova, Olena;Kuchai, Tetiana
    • International Journal of Computer Science & Network Security
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    • v.22 no.9
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    • pp.35-42
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    • 2022
  • The article deals with the role of extra-curricular work by means of multimedia technologies in order to improve the quality of training of future specialists. An important condition for achieving high results in training specialists is the optimal combination of classroom and independent extra-curricular work of students by means of multimedia technologies. Very significant is the development of student independence, the formation of skills of independent search activity, the ability to take responsibility, independently solve a problem, find constructive solutions, a way out of a crisis situation, and so on. Extra-curricular work forms students' ability to master the techniques of analysis, synthesis, generalization, comparison; develops flexibility of thinking; opens up opportunities for the development and stabilization of positive learning motives to activate the process of mastering knowledge by means of multimedia technologies as a means of forming the personality of a highly qualified specialist. The concept of multimedia as one of the priority areas of Information Technology, which plays a particularly important role in the process of informatization of education, is revealed, and its advantages in education are shown. The advent of multimedia systems optimizes transformations in education, in many areas of professional activity, science, art, etc. The necessity of distance learning to improve the quality of training of future specialists using multimedia technologies in extra-curricular work is justified. The effectiveness of pedagogical support in the process of distance learning is achieved by the following conditions, which is revealed in the article. Various forms and types of extra-curricular work of students that are used in the modern practice of the educational environment of a higher education institution are described. Scientific and informational activity is considered a key area of information activity. The analysis of scientific and information activities in the field of education allows us to identify its main functions, which emphasize the growing role of scientific information in the education system, in particular, extra-curricular work using multimedia technologies. Operational, complete, accurate, targeted information that meets objective and subjective needs becomes an important link between the field of management, science and practice.

Effectiveness of Acupotomy for Migraine: A Systematic Review (편두통의 침도 치료에 대한 체계적 문헌고찰)

  • Seok-Hee Jeon;Soo-Min Jeong;Jeong-Cheol Shin
    • Korean Journal of Acupuncture
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    • v.40 no.3
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    • pp.62-78
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    • 2023
  • Objectives : This study aims to assess the impact of acupotomy on migraine through an examination of clinical studies conducted since 2015. Methods : We conducted a comprehensive search for randomized controlled trials (RCTs) and non-randomized controlled trials (nRCTs) related to acupotomy treatment for migraine, utilizing five Korean online databases (OASIS, Science ON, DBPIA, KISS, RISS), as well as four foreign online databases (CNKI, PubMed, EMBASE, Cochrane Library). We identified a total of 10 relevant studies for analysis. Participants characteristics, treatment points, combination treatments, treatment cycles or frequencies, evaluation indices, efficacy, and adverse events were analyzed. The risk of bias in the 10 RCTs was assessed using the Revised Cochrane risk-of-bias tool for randomized trials (RoB 2.0). Results : A total of 931 participants were included in 10 studies. In the intervention group, the average duration of migraine morbidity ranged from 15.5±4.5 months to 15.9±4.2 years. Six studies based their diagnoses on the International Classification of Headache Disorders (ICHD), while five studies relied on Chinese diagnostic criteria. All studies specified the treatment area as the region exhibiting tenderness or induration on the head and neck. Treatment cycles ranged from a minimum of 2 days to a maximum of 1 week, with the number of days per treatment course varied from 5 days to 4 weeks. The diameter of acupuncture needles used varied between 0.3 mm and 1 mm. Of the eight studies specifying needle length, the shortest was 20 mm, and the longest was 40 mm. A total of eight evaluation indices were employed, with total efficacy rate (TER) and visual analogue scale (VAS) being the most frequently used. Statistically, all intervention groups showed more significant results compared to the control groups. Adverse events were reported in only two studies within the intervention group. Overall, the risk of bias assessment for the selected RCTs ranged from 'some concerns' to 'high risk of bias.' Conclusions : This study showed that acupotomy treatments for migraine were effective.

The Influence of Perceived Burdensomeness on Suicidal Ideation of Older Adults: Moderated Mediating Effects of Meaning in Life and Social Participation (인식된 짐스러움이 노인 자살사고에 미치는 영향: 삶의 의미와 사회참여의 조절된 매개효과)

  • Juan Hong;Hoin Kwon
    • Korean Journal of Culture and Social Issue
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    • v.24 no.3
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    • pp.411-428
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    • 2018
  • This study has attempted to identify whether or not the effects of perceived burdensomeness and thwarted belongingness of the elderly on a suicidal ideation is mediated by the meaning in life and, during this process, examined if social participation known as a protective factor against elderly suicide has a moderating effect. For this, a total of 403 elderly men and women residing in Honam area have been selected as the subjects of the study, among whom self-report surveys have been conducted as to perceived burdensomeness, thwarted belongingness, meaning in life (presence of meaning/search for meaning) and social participation. The mediating analysis with the use of the process macro has identified the path where the perceived burdensomeness encourages a suicidal ideation through the presence of the meaning in life. On the other hand, the thwarted belongingness has turned out to be significant only in a direct path to a suicidal ideation. The analysis results of moderated mediating effects, including social participation have found that social participation does mediate the path to a suicidal ideation caused by the perceived burdensomeness through the presence of the meaning in life, verifying its moderated mediating effects.

Analysis of Research Trends of 'Word of Mouth (WoM)' through Main Path and Word Co-occurrence Network (주경로 분석과 연관어 네트워크 분석을 통한 '구전(WoM)' 관련 연구동향 분석)

  • Shin, Hyunbo;Kim, Hea-Jin
    • Journal of Intelligence and Information Systems
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    • v.25 no.3
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    • pp.179-200
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    • 2019
  • Word-of-mouth (WoM) is defined by consumer activities that share information concerning consumption. WoM activities have long been recognized as important in corporate marketing processes and have received much attention, especially in the marketing field. Recently, according to the development of the Internet, the way in which people exchange information in online news and online communities has been expanded, and WoM is diversified in terms of word of mouth, score, rating, and liking. Social media makes online users easy access to information and online WoM is considered a key source of information. Although various studies on WoM have been preceded by this phenomenon, there is no meta-analysis study that comprehensively analyzes them. This study proposed a method to extract major researches by applying text mining techniques and to grasp the main issues of researches in order to find the trend of WoM research using scholarly big data. To this end, a total of 4389 documents were collected by the keyword 'Word-of-mouth' from 1941 to 2018 in Scopus (www.scopus.com), a citation database, and the data were refined through preprocessing such as English morphological analysis, stopwords removal, and noun extraction. To carry out this study, we adopted main path analysis (MPA) and word co-occurrence network analysis. MPA detects key researches and is used to track the development trajectory of academic field, and presents the research trend from a macro perspective. For this, we constructed a citation network based on the collected data. The node means a document and the link means a citation relation in citation network. We then detected the key-route main path by applying SPC (Search Path Count) weights. As a result, the main path composed of 30 documents extracted from a citation network. The main path was able to confirm the change of the academic area which was developing along with the change of the times reflecting the industrial change such as various industrial groups. The results of MPA revealed that WoM research was distinguished by five periods: (1) establishment of aspects and critical elements of WoM, (2) relationship analysis between WoM variables, (3) beginning of researches of online WoM, (4) relationship analysis between WoM and purchase, and (5) broadening of topics. It was found that changes within the industry was reflected in the results such as online development and social media. Very recent studies showed that the topics and approaches related WoM were being diversified to circumstantial changes. However, the results showed that even though WoM was used in diverse fields, the main stream of the researches of WoM from the start to the end, was related to marketing and figuring out the influential factors that proliferate WoM. By applying word co-occurrence network analysis, the research trend is presented from a microscopic point of view. Word co-occurrence network was constructed to analyze the relationship between keywords and social network analysis (SNA) was utilized. We divided the data into three periods to investigate the periodic changes and trends in discussion of WoM. SNA showed that Period 1 (1941~2008) consisted of clusters regarding relationship, source, and consumers. Period 2 (2009~2013) contained clusters of satisfaction, community, social networks, review, and internet. Clusters of period 3 (2014~2018) involved satisfaction, medium, review, and interview. The periodic changes of clusters showed transition from offline to online WoM. Media of WoM have become an important factor in spreading the words. This study conducted a quantitative meta-analysis based on scholarly big data regarding WoM. The main contribution of this study is that it provides a micro perspective on the research trend of WoM as well as the macro perspective. The limitation of this study is that the citation network constructed in this study is a network based on the direct citation relation of the collected documents for MPA.